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Journal Articles

Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4 -r cases

Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Pablo Peña-Martínez, Ludvig Sjöström, Helena Ågerstam, Carl Sandén, Marianne Rissler, Anders Castor, Hanne Marquart, Signe Modvig, Kajsa Paulsson, Cornelis Jan Pronk, Kjeld Schmiegelow, Axel Hyrenius-Wittsten, Christina Orsmark-Pietras, Henrik Lilljebjörn, Thoas Fioretos

Blood (2024) 144 (13): 1399–1411.

https://doi.org/10.1182/blood.2023021705

Published: 2024

Includes: Supplemental data

Journal Articles

Single-Cell Transcriptomics Points to a Role of Stemness and Bone Marrow Niche Interactions in the Poor Response to Induction Therapy in T-Cell Acute Lymphoblastic Leukemia

Signe Modvig, Hanna Thorsson, Bodil Als-Nielsen, Claus Christensen, Nina Friesgaard Øbro, Hans O. Madsen, Henrik Lilljebjörn, Kjeld Schmiegelow, Thoas Fioretos, Hanne Vibeke Marquart

Blood (2023) 142 (Supplement 1): 4345.

https://doi.org/10.1182/blood-2023-188631

Published: 2023

Journal Articles

Single Cell Multi-Omic Profiling of Acute Lymphoblastic Leukemia Identifies Altered Cellular Pathways and Highlights Heterogeneity in the Maturation Block of DUX4 -Rearranged ALL

Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Carl Sandén, Signe Modvig, Marianne Rissler, Kajsa Paulsson, Anders Castor, Cornelis Jan Pronk, Hanne Vibeke Marquart, Kjeld Schmiegelow, Christina Orsmark-Pietras, Henrik Lilljebjörn, Thoas Fioretos

Blood (2022) 140 (Supplement 1): 3467–3468.

https://doi.org/10.1182/blood-2022-163031

Published: 2022

Journal Articles

Genome-Wide Analysis of Allele-Specific Expression Genes in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

Minjun Yang, Rebeqa Gunnarsson, Linda Olsson, Andrea Biloglav, Henrik Lilljebjörn, Eleanor L Woodward, Thoas Fioretos, Bertil Johansson, Kajsa Paulsson

Blood (2021) 138 (Supplement 1): 4315.

https://doi.org/10.1182/blood-2021-144808

Published: 2021

Journal Articles

AML Xenografts Undergo Extensive Clonal Competition and Unmask Rare Clones in Patient Samples

Carl Sandén, PhD, Henrik Lilljebjörn, PhD, Christina Orsmark-Pietras, PhD, Karim Saba, MSc, Carl Högberg, PhD, Marianne Rissler, MSc, Vladimir Lazarevic, MD PhD, Gunnar Juliusson, MD PhD, Helena Ågerstam, PhD, Thoas Fioretos, MD PhD

Blood (2018) 132 (Supplement 1): 2621.

https://doi.org/10.1182/blood-2018-99-110497

Published: 2018

Journal Articles

Isolated myelosarcoma is characterized by recurrent NFE2 mutations and concurrent preleukemic clones in the bone marrow

Vladimir Lazarevic, Christina Orsmark-Pietras, Henrik Lilljebjörn, Louise Pettersson, Marianne Rissler, Anna Lübking, Mats Ehinger, Gunnar Juliusson, Thoas Fioretos

Blood (2018) 131 (5): 577–581.

https://doi.org/10.1182/blood-2017-07-793620

Published: 2018

Includes: Supplemental data

Journal Articles

The Proteogenomic Landscape of High Hyperdiploid and ETV6/RUNX1-Positive Childhood Acute Lymphoblastic Leukemia

Minjun Yang, Mattias Vesterlund, Ioannis Siavelis, Eleanor Woodward, Naveen Ravi, Henrik Lilljebjörn, MSc, Thoas Fioretos, MD PhD, Janne Lehtiö, Kajsa Paulsson

Blood (2017) 130 (Supplement 1): 1433.

https://doi.org/10.1182/blood.V130.Suppl_1.1433.1433

Published: 2017

Journal Articles

Monitoring Leukemic Mutations Using Ultrasensitive IBSAFE Digital Droplet Analysis Predicts Relapse of Acute Myeloid Leukemia

Louise Pettersson, MD, Yilun Chen, MSc, Anthony M George, MSc, Christina Orsmark-Pietras, PhD, Henrik Lilljebjörn, MSc, Robert Rigo, MSc, Vladimir Lazarevic, MD PhD, Thoas Fioretos, MD PhD, Gunnar Juliusson, MD PhD, Mats Ehinger, MD PhD, Lao H Saal, MD PhD

Blood (2017) 130 (Supplement 1): 3951.

https://doi.org/10.1182/blood.V130.Suppl_1.3951.3951

Published: 2017

Journal Articles

New oncogenic subtypes in pediatric B-cell precursor acute lymphoblastic leukemia

Henrik Lilljebjörn, Thoas Fioretos

Blood (2017) 130 (12): 1395–1401.

https://doi.org/10.1182/blood-2017-05-742643

Published: 2017

Journal Articles

IL1RAP antibodies block IL-1–induced expansion of candidate CML stem cells and mediate cell killing in xenograft models

Helena Ågerstam, Nils Hansen, Sofia von Palffy, Carl Sandén, Kristian Reckzeh, Christine Karlsson, Henrik Lilljebjörn, Niklas Landberg, Maria Askmyr, Carl Högberg, Marianne Rissler, Kimmo Porkka, Hans Wadenvik, Satu Mustjoki, Johan Richter, Marcus Järås, Thoas Fioretos

Blood (2016) 128 (23): 2683–2693.

https://doi.org/10.1182/blood-2015-11-679985

Published: 2016

Includes: Supplemental data

Journal Articles

Monitoring Minimal Residual Disease in AML By Patient Specific Mutational Fingerprint Using Multiplex PCR and Deep Sequencing

Christina Orsmark Pietras, Henrik Lilljebjörn, Vladimir Lazarevic, MD, Marianne Rissler, Mats Ehinger, Gunnar Juliusson, MD PhD, Thoas Fioretos

Blood (2016) 128 (22): 1715.

https://doi.org/10.1182/blood.V128.22.1715.1715

Published: 2016

Journal Articles

Mutational and Clonal Dynamics in Patient-Derived Xenografts of Acute Myeloid Leukemia

Carl Sandén, Karim Saba, Christina Orsmark-Pietras, Henrik Lilljebjörn, Carl Högberg, Marianne Rissler, Vladimir Lazarevic, Gunnar Juliusson, Helena Ågerstam, Thoas Fioretos

Blood (2016) 128 (22): 1154.

https://doi.org/10.1182/blood.V128.22.1154.1154

Published: 2016

Journal Articles

IL1RAP Antibodies Block IL1-Induced Expansion of Primitive CML Cells and Display Therapeutic Effects in Xenograft Models

Helena Ågerstam, Nils Hansen, Sofia Von Palffy, Carl Sandén, Kristian Reckzeh, Christine Karlsson, Henrik Lilljebjörn, Niklas Landberg, Maria Askmyr, Carl Högberg, Marianne Rissler, Kimmo Porkka, Hans Wadenvik, Satu Mustjoki, Johan Richter, MD, Marcus Järås, Thoas Fioretos

Blood (2016) 128 (22): 1118.

https://doi.org/10.1182/blood.V128.22.1118.1118

Published: 2016

Journal Articles

Comprehensive Prospective Next Generation Sequencing of Acute Myeloid Leukemia

Christina Orsmark-Pietras, Henrik Lilljebjörn, Marianne Rissler, Vladimir Lazarevic, Alexandros Arvanitakis, Mats Ehinger, Gunnar Juliusson, MD PhD, Thoas Fioretos

Blood (2015) 126 (23): 3830.

https://doi.org/10.1182/blood.V126.23.3830.3830

Published: 2015

Journal Articles

Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency

Mahadesh A. J. Prasad, Jonas Ungerbäck, Josefine Åhsberg, Rajesh Somasundaram, Tobias Strid, Malin Larsson, Robert Månsson, Ayla De Paepe, Henrik Lilljebjörn, Thoas Fioretos, James Hagman, Mikael Sigvardsson

Blood (2015) 125 (26): 4052–4059.

https://doi.org/10.1182/blood-2014-12-617282

Published: 2015

Includes: Supplemental data

Journal Articles

Modeling Chronic Myeloid Leukemia in Immunodeficient Mice Reveals an Inflammatory State with Expansion of Aberrant Mast Cells and Accumulation of Pre B Cells

Maria Askmyr, PhD, Helena Agerstam, PhD, Henrik Lilljebjörn, PhD, Nils Hansen, PhD, Christine Karlsson, PhD, Niklas Landberg, Carl Hogberg, PhD, Carin Lassen, Msc, Marianne Rissler, Johan Richter, MD PhD, Mats Ehinger, MD PhD, Marcus Jaras, PhD, Thoas Fioretos, MD PhD

Blood (2014) 124 (21): 3132.

https://doi.org/10.1182/blood.V124.21.3132.3132

Published: 2014

NARROW

Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4 -r cases

Single-Cell Transcriptomics Points to a Role of Stemness and Bone Marrow Niche Interactions in the Poor Response to Induction Therapy in T-Cell Acute Lymphoblastic Leukemia

Single Cell Multi-Omic Profiling of Acute Lymphoblastic Leukemia Identifies Altered Cellular Pathways and Highlights Heterogeneity in the Maturation Block of DUX4 -Rearranged ALL

Genome-Wide Analysis of Allele-Specific Expression Genes in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

AML Xenografts Undergo Extensive Clonal Competition and Unmask Rare Clones in Patient Samples

Isolated myelosarcoma is characterized by recurrent NFE2 mutations and concurrent preleukemic clones in the bone marrow

The Proteogenomic Landscape of High Hyperdiploid and ETV6/RUNX1-Positive Childhood Acute Lymphoblastic Leukemia

Monitoring Leukemic Mutations Using Ultrasensitive IBSAFE Digital Droplet Analysis Predicts Relapse of Acute Myeloid Leukemia

New oncogenic subtypes in pediatric B-cell precursor acute lymphoblastic leukemia

IL1RAP antibodies block IL-1–induced expansion of candidate CML stem cells and mediate cell killing in xenograft models

Monitoring Minimal Residual Disease in AML By Patient Specific Mutational Fingerprint Using Multiplex PCR and Deep Sequencing

Mutational and Clonal Dynamics in Patient-Derived Xenografts of Acute Myeloid Leukemia

IL1RAP Antibodies Block IL1-Induced Expansion of Primitive CML Cells and Display Therapeutic Effects in Xenograft Models

Comprehensive Prospective Next Generation Sequencing of Acute Myeloid Leukemia

Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency

Modeling Chronic Myeloid Leukemia in Immunodeficient Mice Reveals an Inflammatory State with Expansion of Aberrant Mast Cells and Accumulation of Pre B Cells

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American Society of Hematology

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American Society of Hematology

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