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Jamie M. O'Sullivan
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Journal Articles

Targeted Inhibition of Phosphodiesterase (PDE) 4 As a Novel Therapy to Increase Endothelial Cell cAMP and Trigger Weibel Palade Body Exocytosis

Dearbhla Doherty, Ellie Karampini, Ciara Byrne, Ingmar Schoen, Roger J.S Preston, Jamie M O'Sullivan, Michelle Lavin, James O'Donnell
Journal: Blood
Blood (2023) 142 (Supplement 1): 3975.
https://doi.org/10.1182/blood-2023-178581
Published: 2023
Journal Articles

Primary Myeloma Cell Induced Von Willebrand Factor Release from the Endothelium Is Mediated By VEGF and Attenuated By Heparin

Claire Comerford, Sukhraj Pal Singh Dhami, Philip Murphy, Sean Patmore, Siobhan Glavey, John Quinn, Jamie M. O'Sullivan
Journal: Blood
Blood (2021) 138 (Supplement 1): 3141.
https://doi.org/10.1182/blood-2021-149134
Published: 2021
Journal Articles

The relationship between ABO blood group, von Willebrand factor, and primary hemostasis

Soracha E. Ward, Jamie M. O’Sullivan, James S. O’Donnell
Journal: Blood
Blood (2020) 136 (25): 2864–2874.
https://doi.org/10.1182/blood.2020005843
Published: 2020
Journal Articles

von Willebrand factor promotes wound healing

James S. O’Donnell, Jamie M. O’Sullivan
Journal: Blood
Blood (2019) 133 (24): 2553–2555.
https://doi.org/10.1182/blood.2019001175
Published: 2019
Journal Articles

Increased galactose expression and enhanced clearance in patients with low von Willebrand factor

Sonia Aguila, Michelle Lavin, Niall Dalton, Sean Patmore, Alain Chion, George D. Trahan, Kenneth L. Jones, Catriona Keenan, Teresa M. Brophy, Niamh M. O’Connell, Kevin Ryan, Mary Byrne, Margaret Nolan, Anjali Patel, Roger J. S. Preston, Paula James, Jorge Di Paola, Jamie M. O’Sullivan, James S. O’Donnell
Journal: Blood
Blood (2019) 133 (14): 1585–1596.
https://doi.org/10.1182/blood-2018-09-874636
Published: 2019
Includes: Supplemental data
Journal Articles

Blood group alters platelet binding kinetics to von Willebrand factor and consequently platelet function

Eimear Dunne, Qin M. Qi, Eric S. Shaqfeh, Jamie M. O’Sullivan, Ingmar Schoen, Antonio J. Ricco, James S. O’Donnell, Dermot Kenny
Journal: Blood
Blood (2019) 133 (12): 1371–1377.
https://doi.org/10.1182/blood-2018-06-855528
Published: 2019
Includes: Multimedia, Supplemental data
Journal Articles

Defining the Molecular Mechanisms through Which the Macrophage Galactose Lectin (MGL) Receptor Regulates Von Willebrand Factor Clearance

Soracha E Ward, BSc, Jamie M O'Sullivan, Sonia Aguila Martinez, BSc, PhD, Clive Drakeford, BSc, Thomas Anthony Jude McKinnon, BSc, PhD, Alain Chion, BSc, PhD, James S O'Donnell, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 980.
https://doi.org/10.1182/blood-2018-99-114775
Published: 2018
Journal Articles

Site-Directed Pegylation at Specific Sites Significantly Prolongs the Half-Life of A1A2A3-VWF By Markedly Attenuating LRP1-Mediated Clearance

Jamie M O'Sullivan, Judicael Fazavana, PhD, Alain Chan, PhD, Niamh Cooke, PhD, Virginie Terraube, Justin Cohen, PhD, Debra D Pittman, MS, Orla Cunningham, PhD, Matthew Lambert, James S O'Donnell, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1165.
https://doi.org/10.1182/blood-2018-99-114966
Published: 2018
Journal Articles

The Low Von Willebrand Factor in Ireland Cohort Study - Defining Optimal Management for Procedures in Patients with Low VWF (30-50 IU/dL)

Dearbhla Doherty, MB, MRCPI, Anjali Patel, Margaret Nolan, Mary Byrne, Sonia Aguila, PhD, Jamie M O'Sullivan, Kevin Ryan, MB, FRCPath, Niamh M O'Connell, MB, PhD FRCPath, Michelle Lavin, MB, PhD FRCPath, James S O'Donnell, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1178.
https://doi.org/10.1182/blood-2018-99-115946
Published: 2018
Journal Articles

Platelets in malaria pathogenesis

Jamie M. O’Sullivan, James S. O’Donnell
Journal: Blood
Blood (2018) 132 (12): 1222–1224.
https://doi.org/10.1182/blood-2018-08-865618
Published: 2018
Journal Articles

A novel role for the macrophage galactose-type lectin receptor in mediating von Willebrand factor clearance

Brief Report
Soracha E. Ward, Jamie M. O’Sullivan, Clive Drakeford, Sonia Aguila, Christopher N. Jondle, Jyotika Sharma, Padraic G. Fallon, Teresa M. Brophy, Roger J. S. Preston, Paul Smyth, Orla Sheils, Alain Chion, James S. O’Donnell
Journal: Blood
Blood (2018) 131 (8): 911–916.
https://doi.org/10.1182/blood-2017-06-787853
Published: 2018
Includes: Supplemental data
Journal Articles

Novel insights into the clinical phenotype and pathophysiology underlying low VWF levels

Clinical Trials & Observations
Michelle Lavin, Sonia Aguila, Sonja Schneppenheim, Niall Dalton, Kenneth L. Jones, Jamie M. O’Sullivan, Niamh M. O’Connell, Kevin Ryan, Barry White, Mary Byrne, Marie Rafferty, Mairead M. Doyle, Margaret Nolan, Roger J. S. Preston, Ulrich Budde, Paula James, Jorge Di Paola, James S. O’Donnell
Journal: Blood
Blood (2017) 130 (21): 2344–2353.
https://doi.org/10.1182/blood-2017-05-786699
Published: 2017
Includes: Supplemental data
Journal Articles

Novel Insights into the Clinical Phenotype and Pathophysiology Underlying Low VWF Levels: The Low Von Willebrand Factor in Ireland Cohort (LoVIC) Study

Michelle Lavin, MB FRCPath, Sonia Aguila, PhD, Sonja Schneppenheim, MD, Niall Dalton, BSc, Jamie M O'Sullivan, PhD, Niamh M O'Connell, MB, FRCPath, PhD, Kevin M. Ryan, MB, Mary Byrne, MSc, Margaret Nolan, BSc, Roger Preston, PhD, Ulrich Budde, MD, Paula D. James, MD, Jorge Di Paola, MD, James S O'Donnell, MD PhD
Journal: Blood
Blood (2016) 128 (22): 873.
https://doi.org/10.1182/blood.V128.22.873.873
Published: 2016
Journal Articles

N-linked glycans within the A2 domain of von Willebrand factor modulate macrophage-mediated clearance

Alain Chion, Jamie M. O’Sullivan, Clive Drakeford, Gudmundur Bergsson, Niall Dalton, Sonia Aguila, Soracha Ward, Padraic G. Fallon, Teresa M. Brophy, Roger J. S. Preston, Lauren Brady, Orla Sheils, Michael Laffan, Thomas A. J. McKinnon, James S. O’Donnell
Journal: Blood
Blood (2016) 128 (15): 1959–1968.
https://doi.org/10.1182/blood-2016-04-709436
Published: 2016
Includes: Supplemental data
Journal Articles

Emerging roles for hemostatic dysfunction in malaria pathogenesis

Jamie M. O’Sullivan, Roger J. S. Preston, Niamh O’Regan, James S. O’Donnell
Journal: Blood
Blood (2016) 127 (19): 2281–2288.
https://doi.org/10.1182/blood-2015-11-636464
Published: 2016
Journal Articles

A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria

Niamh O’Regan, Kristina Gegenbauer, Jamie M. O’Sullivan, Sanaz Maleki, Teresa M. Brophy, Niall Dalton, Alain Chion, Padraic G. Fallon, Georges E. Grau, Ulrich Budde, Owen P. Smith, Alister G. Craig, Roger J. S. Preston, James S. O’Donnell
Journal: Blood
Blood (2016) 127 (9): 1192–1201.
https://doi.org/10.1182/blood-2015-07-654921
Published: 2016
Includes: Supplemental data
Journal Articles

Altered glycosylation of platelet-derived von Willebrand factor confers resistance to ADAMTS13 proteolysis

Brief Report
Rachel T. McGrath, Maartje van den Biggelaar, Barry Byrne, Jamie M. O’Sullivan, Orla Rawley, Richard O’Kennedy, Jan Voorberg, Roger J. S. Preston, James S. O’Donnell
Journal: Blood
Blood (2013) 122 (25): 4107–4110.
https://doi.org/10.1182/blood-2013-04-496851
Published: 2013