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Lewis B Silverman
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Journal Articles

Venous Thromboembolism in Adolescents and Young Adults with Acute Lymphoblastic Leukemia Treated on a Pediatric-Inspired Regimen

Hari S. Raman, Shai Shimony, Yannis K. Valtis, Yael Flamand, Andrew E. Place, Lewis B. Silverman, Stephen E. Sallan, Lynda M. Vrooman, Andrew M. Brunner, Donna S. Neuberg, Ilene Galinsky, Jacqueline S. Garcia, Eric S. Winer, Martha Wadleigh, Richard M Stone, Jean M. Connors, Daniel J. DeAngelo, Marlise R. Luskin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1456.
https://doi.org/10.1182/blood-2023-178353
Published: 2023
Journal Articles

Oral Chemotherapy Adherence in Pediatric Acute Lymphoblastic Leukemia (ALL): A Report from the Dana-Farber Cancer Institute (DFCI) ALL Consortium Protocol 16-001

Justine M. Kahn, Hital Patel, Julia Keating, Yael Flamand, Victoria Koch, Peter D. Cole, Lisa M. Gennarini, Bruno Michon, Thai Hoa Tran, Jennifer J.G. Welch, Lewis B. Silverman, Elizabeth Bouchard, Kira Bona, Kara M. Kelly
Journal: Blood
Blood (2023) 142 (Supplement 1): 7375.
https://doi.org/10.1182/blood-2023-189447
Published: 2023
Journal Articles

Efficacy and Safety of Recombinant Erwinia Asparaginase (JZP458) in Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL): Complete Follow-up of the Children's Oncology Group (COG) AALL1931 Study

Luke Maese, Mignon L. Loh, Mi Rim Choi, Tong Lin, Etsuko Aoki, Shirali Agarwal, Vijayalakshmi Chandrasekaran, Yali Liang, Suzette Girgis, Cuiping Chen, Robert Iannone, Lewis B. Silverman, Elizabeth A. Raetz, Rachel E. Rau
Journal: Blood
Blood (2023) 142 (Supplement 1): 1498.
https://doi.org/10.1182/blood-2023-172577
Published: 2023
Journal Articles

Updated Results on a Multicenter Phase II Study of a Dose Intensified Pediatric Regimen in Adults with Acute Lymphoblastic Leukemia: The 06-254 DFCI ALL Consortium Trial

Yannis K. Valtis, Yael Flamand, Shai Shimony, Andrew E. Place, Lewis B. Silverman, Lynda M. Vrooman, Andrew M. Brunner, Stephen E. Sallan, Martha Wadleigh, Jacqueline S. Garcia, Eric S. Winer, Ilene Galinsky, Julie Bergeron, Julie Asch, Matthew D. Seftel, Richard M Stone, Marlise R. Luskin, Daniel J. DeAngelo
Journal: Blood
Blood (2023) 142 (Supplement 1): 4238.
https://doi.org/10.1182/blood-2023-181014
Published: 2023
Journal Articles

Immunogenicity of Recombinant Erwinia asparaginase (JZP458) for Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)

Luke Maese, Mignon L. Loh, Mi Rim Choi, Yali Liang, Etsuko Aoki, Shane Roller, Tong Lin, Shirali Agarwal, Vijayalakshmi Chandrasekaran, Robert Iannone, Lewis B. Silverman, Elizabeth A. Raetz, Rachel E. Rau
Journal: Blood
Blood (2023) 142 (Supplement 1): 5908.
https://doi.org/10.1182/blood-2023-179533
Published: 2023
Journal Articles

Recombinant Erwinia asparaginase (JZP458) in acute lymphoblastic leukemia: results from the phase 2/3 AALL1931 study

Clinical Trials & Observations
Luke Maese, Mignon L. Loh, Mi Rim Choi, Tong Lin, Etsuko Aoki, Michelle Zanette, Shirali Agarwal, Robert Iannone, Jeffrey A. Silverman, Lewis B. Silverman, Elizabeth A. Raetz, Rachel E. Rau
Journal: Blood
Blood (2023) 141 (7): 704–712.
https://doi.org/10.1182/blood.2022016923
Published: 2023
Includes: Supplemental data
Journal Articles

Children with Acute Lymphoblastic Leukemia and Early Thrombosis Have Dysregulated Coagulation-Related Genes and Pathways

Raoul Santiago, Marie-Claude Pelland-Marcotte, Arnaud Droit, Jeyani George Clement, Lara Herrmann, Meredith Michelle Rémy, Yan Ma, Virgile Raufaste-Cazavieille, Jessica Liu, Charles Joly-Beauparlant, Mickael Leclercq, Camille Jimenez-Cortes, Thomas Sontag, Maxime Caron, Pascal St-Onge, Sylvie Langlois, Victoria Koch, Daniel Sinnett, Lewis B. Silverman, Thai Hoa Tran
Journal: Blood
Blood (2022) 140 (Supplement 1): 1971–1973.
https://doi.org/10.1182/blood-2022-163334
Published: 2022
Journal Articles

Single-Cell Multi-Omics Reveals Immune Microenvironment Alterations in T-Cell Acute Lymphoblastic Leukemia

Caroline R.M. Wiggers, Eugene Y. Cho, Justin Hegel, Julia Frede, Hannah Stuart, Klothilda K. Lim, Yana Pikman, Marian H. Harris, Andrew E. Place, Lewis B. Silverman, Jens G. Lohr, Birgit Knoechel
Journal: Blood
Blood (2022) 140 (Supplement 1): 9192–9193.
https://doi.org/10.1182/blood-2022-166511
Published: 2022
Journal Articles

Adolescent and Young Adults with ALL Who Complete Therapy on DFCI Consortium ALL Trials Have Excellent Long-Term Overall Survival

Yannis K. Valtis, Yael Flamand, Shai Shimony, Andrew E. Place, Lewis B. Silverman, Lynda M. Vrooman, Andrew M. Brunner, Stephen E. Sallan, Martha Wadleigh, Richard M. Stone, Daniel J DeAngelo, Marlise R. Luskin
Journal: Blood
Blood (2022) 140 (Supplement 1): 8901–8903.
https://doi.org/10.1182/blood-2022-159286
Published: 2022
Journal Articles

Nelarabine Combination Therapy for Relapsed or Refractory T-Cell Acute Lymphoblastic Lymphoma/Leukemia

Shai Shimony, Yiwen Liu, Yannis K. Valtis, Jonathan D. Paolino, Andrew E. Place, Andrew M. Brunner, Lachelle D. Weeks, Lewis B. Silverman, Lynda M. Vrooman, Donna S. Neuberg, Richard M. Stone, Daniel J. DeAngelo, Marlise R. Luskin
Journal: Blood
Blood (2022) 140 (Supplement 1): 8989–8990.
https://doi.org/10.1182/blood-2022-157545
Published: 2022
Journal Articles

Body Mass Index Effect on Survival and Toxicities Differs between Age Groups Among Adolescents and Young Adults Treated on DFCI Consortium ALL Trials

Shai Shimony, Yael Flamand, Yannis K. Valtis, Andrew E. Place, Lewis B. Silverman, Lynda M. Vrooman, Andrew M. Brunner, Stephen E. Sallan, Richard M. Stone, Martha Wadleigh, Donna S. Neuberg, Daniel J DeAngelo, Marlise R. Luskin
Journal: Blood
Blood (2022) 140 (Supplement 1): 3164–3165.
https://doi.org/10.1182/blood-2022-158348
Published: 2022
Journal Articles

Efficacy, Safety, and Population Pharmacokinetic Modeling of Intravenous Recombinant Erwinia Asparaginase (JZP458) in Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma: Results from Study AALL1931

Luke Maese, Mignon L. Loh, Mi Rim Choi, Tong Lin, Etsuko Aoki, Shirali Agarwal, Xiaotian Wu, Robert Iannone, Jeffrey A. Silverman, Lewis B. Silverman, Elizabeth A. Raetz, Rachel E. Rau
Journal: Blood
Blood (2022) 140 (Supplement 1): 8969–8970.
https://doi.org/10.1182/blood-2022-160192
Published: 2022
Journal Articles

Remission, treatment failure, and relapse in pediatric ALL: an international consensus of the Ponte-di-Legno Consortium

Clinical Trials & Observations
Swantje Buchmann, Martin Schrappe, Andre Baruchel, Andrea Biondi, Michael Borowitz, Myriam Campbell, Gunnar Cario, Giovanni Cazzaniga, Gabriele Escherich, Christine J. Harrison, Mats Heyman, Stephen P. Hunger, Csongor Kiss, Hsi-Che Liu, Franco Locatelli, Mignon L. Loh, Atsushi Manabe, Georg Mann, Rob Pieters, Ching-Hon Pui, Susana Rives, Kjeld Schmiegelow, Lewis B. Silverman, Jan Stary, Ajay Vora, Patrick Brown
Journal: Blood
Blood (2022) 139 (12): 1785–1793.
https://doi.org/10.1182/blood.2021012328
Published: 2022
Includes: Supplemental data
Journal Articles

Vincristine Sulfate Liposome Injection (VSLI, Marqibo®) in Combination with UK ALL-R3 Induction Chemotherapy for Children, Adolescents and Young Adults with Relapsed Acute Lymphoblastic Leukemia (ALL): A Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) Consortium Trial

Nirali N. Shah, Eric S Schafer, Kenneth Matthew Heym, Andrew E. Place, Melissa A. Burns, Nathan Gossai, Peter Shaw, Michael J. Burke, Bill H. Chang, Michelle L. Hermiston, Reuven J Schore, Teresa Rushing, Paul F Jarosinski, Richard Sposto, Ellynore Florendo, Jemily Malvar, Yueh-Yun Chi, James A. Whitlock, Lewis B. Silverman, Deepa Bhojwani, Alan S. Wayne
Journal: Blood
Blood (2021) 138 (Supplement 1): 3402.
https://doi.org/10.1182/blood-2021-149365
Published: 2021
Journal Articles

Performance of Next Generation Sequencing for Minimal Residual Disease Detection for Pediatric Patients with Acute Lymphoblastic Leukemia: Results from the Prospective Clinical Trial DFCI 16-001

Jonathan D. Paolino, Marian H. Harris, Kristen E. Stevenson, Victoria Koch, Peter D. Cole, Lisa M. Gennarini, Justine M. Kahn, Kara M. Kelly, IIan Kirsch, Bruno Michon, Andrew E. Place, Thai Hoa Tran, Jennifer J.G. Welch, Lewis B. Silverman
Journal: Blood
Blood (2021) 138 (Supplement 1): 3485.
https://doi.org/10.1182/blood-2021-152369
Published: 2021
Journal Articles

Initial Results from a Phase 2/3 Study of Recombinant Erwinia Asparaginase (JZP458) in Patients with Acute Lymphoblastic Leukemia (ALL)/Lymphoblastic Lymphoma (LBL) Who Are Allergic/Hypersensitive to E. coli-Derived Asparaginases

Luke Maese, Mignon L. Loh, Tong Lin, Etsuko Aoki, Michelle Zanette, Shirali Agarwal, Jeffrey A. Silverman, Mi Rim Choi, Lewis B. Silverman, Elizabeth A. Raetz, Rachel E. Rau
Journal: Blood
Blood (2021) 138 (Supplement 1): 2307.
https://doi.org/10.1182/blood-2021-147023
Published: 2021
Journal Articles

Minimal Residual Disease and Outcome Characteristics in Infant KMT2A-Germline Acute Lymphoblastic Leukemia Treated on the Interfant-06 Protocol

Janine Stutterheim, Paola De Lorenzo, Inge M. Van Der Sluis, Julia Alten, Philip Ancliffe, Andishe Attarbaschi, Luis Alberto Aversa, Judith M. Boer, Andrea Biondi, Benoit Brethon, Paulina Diaz, Giovanni Gazzaniga, Gabriele Escherich, Alina Ferster, Rishi S Kotecha, Birgitte Lausen, Alex WK Leung, Franco Locatelli, Lewis B. Silverman, Jan Stary, Tomasz Szczepanski, Vincent H.J. Van Der Velden, Ajay Vora, Jan Zuna, Martin Schrappe, Maria Grazia Valsecchi, Rob Pieters
Journal: Blood
Blood (2021) 138 (Supplement 1): 2383.
https://doi.org/10.1182/blood-2021-145058
Published: 2021
Journal Articles

Low Rates of Venoocclusive Disease and Non-Relapse Mortality in Pediatric Patients Undergoing Allogeneic Hematopoietic Cell Transplantation Following Inotuzumab Ozogamicin Reinduction for Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia

Jonathan D. Paolino, Jiemin Yang, Andrew E. Place, Christine N. Duncan, Steven P. Margossian, Leslie E. Lehmann, John T. Horan, Malika Kapadia, Jennifer S. Whangbo, Francesca Alvarez Calderon, Melissa A. Burns, Leslie S. Kean, Lewis B. Silverman, Donna S. Neuberg, Susanne H.C. Baumeister
Journal: Blood
Blood (2021) 138 (Supplement 1): 2853.
https://doi.org/10.1182/blood-2021-152857
Published: 2021
Journal Articles

Impact of Age, Body Surface Area, and Body Mass Index on Pegaspargase Toxicity and Pharmacokinetics: A Report from the DFCI ALL Consortium

Jonathan D. Paolino, Yael Flamand, Kristen E. Stevenson, Victoria Koch, Uma H. Athale, Peter D. Cole, Lisa M. Gennarini, Justine M. Kahn, Kara M. Kelly, Caroline Laverdiere, Jean-Marie Leclerc, Bruno Michon, Andrew E. Place, Jeffrey G. Supko, Thai Hoa Tran, Jennifer J.G. Welch, Donna S. Neuberg, Stephen E. Sallan, Lewis B. Silverman, Lynda M. Vrooman
Journal: Blood
Blood (2021) 138 (Supplement 1): 3396.
https://doi.org/10.1182/blood-2021-151313
Published: 2021
Journal Articles

Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL

Praveen Anand, Amy Guillaumet-Adkins, Valeriya Dimitrova, Huiyoung Yun, Yotam Drier, Noori Sotudeh, Anna Rogers, Madhu M. Ouseph, Monica Nair, Sayalee Potdar, Randi Isenhart, Jake A. Kloeber, Tushara Vijaykumar, Leili Niu, Tiffaney Vincent, Guangwu Guo, Julia Frede, Marian H. Harris, Andrew E. Place, Lewis B. Silverman, David T. Teachey, Andrew A. Lane, Daniel J. DeAngelo, Jon C. Aster, Bradley E. Bernstein, Jens G. Lohr, Birgit Knoechel
Journal: Blood
Blood (2021) 137 (18): 2463–2480.
https://doi.org/10.1182/blood.2019004547
Published: 2021
Includes: Supplemental data