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Linda E. Wellik
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Journal Articles

Pembrolizumab in patients with CLL and Richter transformation or with relapsed CLL

Clinical Trials & Observations
Wei Ding, Betsy R. LaPlant, Timothy G. Call, Sameer A. Parikh, Jose F. Leis, Rong He, Tait D. Shanafelt, Sutapa Sinha, Jennifer Le-Rademacher, Andrew L. Feldman, Thomas M. Habermann, Thomas E. Witzig, Gregory A. Wiseman, Yi Lin, Erik Asmus, Grzegorz S. Nowakowski, Michael J. Conte, Deborah A. Bowen, Casey N. Aitken, Daniel L. Van Dyke, Patricia T. Greipp, Xin Liu, Xiaosheng Wu, Henan Zhang, Charla R. Secreto, Shulan Tian, Esteban Braggio, Linda E. Wellik, Ivana Micallef, David S. Viswanatha, Huihuang Yan, Asher A. Chanan-Khan, Neil E. Kay, Haidong Dong, Stephen M. Ansell
Journal: Blood
Blood (2017) 129 (26): 3419–3427.
https://doi.org/10.1182/blood-2017-02-765685
Published: 2017
Includes: Supplemental data
Journal Articles

GATA-3 expression identifies a high-risk subset of PTCL, NOS with distinct molecular and clinical features

Tianjiao Wang, Andrew L. Feldman, David A. Wada, Ye Lu, Avery Polk, Robert Briski, Kay Ristow, Thomas M. Habermann, Dafydd Thomas, Steven C. Ziesmer, Linda E. Wellik, Thomas M. Lanigan, Thomas E. Witzig, Mark R. Pittelkow, Nathanael G. Bailey, Alexandra C. Hristov, Megan S. Lim, Stephen M. Ansell, Ryan A. Wilcox
Journal: Blood
Blood (2014) 123 (19): 3007–3015.
https://doi.org/10.1182/blood-2013-12-544809
Published: 2014
Includes: Supplemental data
Journal Articles

Elevated Soluble IL-2Ra Levels Are Associated With Inferior Outcome and Is Independent Of MIPI Score in Patients With Mantle Cell Lymphoma

Mohamad Bassam, M.D, Matthew J Maurer, MS, Mary Stenson, B.S, Linda E Wellik, Christine Allmer, Brian K Link, MD, James R Cerhan, MD, PhD, Thomas E Witzig, MD, Mamta Gupta, Ph.D
Journal: Blood
Blood (2013) 122 (21): 4256.
https://doi.org/10.1182/blood.V122.21.4256.4256
Published: 2013
Journal Articles

GATA-3 Expression Promotes IL-10 Production, Alternative Macrophage Polarization, and Identifies a Subset Of High-Risk PTCL, NOS

Tianjiao Wang, Ph.D., Andrew L. Feldman, David A Wada, MD, Ye Lu, MD, Avery Polk, BS, Robert Briski, BS, Kay M. Ristow, Thomas M Habermann, MD, Dafydd G Thomas, MD/Ph.D., Steven C. Ziesmer, Linda E Wellik, Thomas Lanigan, Ph.D., Thomas E Witzig, MD, Mark Pittelkow, MD, Nathanael G. Bailey, MD, Megan Lim, MD, PhD, Stephen M Ansell, M.D.Ph.D., Ryan A. Wilcox, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 841.
https://doi.org/10.1182/blood.V122.21.841.841
Published: 2013
Journal Articles

Repression Of Cap-Dependent Translation With a Next-Generation mTOR Inhibitor Attenuates c-Myc Transcription and Survival In Lymphoma Cells

Mamta Gupta, Ph.D, Jing Jing Han, Mary Stenson, B.S, Linda E Wellik, Thomas E Witzig, MD
Journal: Blood
Blood (2013) 122 (21): 636.
https://doi.org/10.1182/blood.V122.21.636.636
Published: 2013
Journal Articles

In-Vivo Activation Of STAT3 In Angioimmunoblastic T Cell Lymphoma, PTCL Not Otherwise Specified, and ALK Negative Anaplastic Large Cell Lymphoma: Implications For Therapy

Mamta Gupta, Ph.D, Matthew J. Maurer, MS, Mary Stenson, B.S, Linda E. Wellik, Jing Jing Han, Andrew L. Feldman, Thomas M. Habermann, MD, Thomas E. Witzig, MD
Journal: Blood
Blood (2013) 122 (21): 844.
https://doi.org/10.1182/blood.V122.21.844.844
Published: 2013
Journal Articles

SHP1 Suppression In Diffuse Large B Cell Lymphoma Is Regulated Through Promoter Hypermethylation At Novel CpG2 Island and H3K27 Trimethylation Histone Mark

Mamta Gupta, Ph.D, Guangzhen Hu, Linda E Wellik, Jing Jing Han, Mary Stenson, B.S, Ahmet Dogan, MD, PhD, Thomas E Witzig, MD
Journal: Blood
Blood (2013) 122 (21): 632.
https://doi.org/10.1182/blood.V122.21.632.632
Published: 2013
Journal Articles

Expression of Myc, but not pSTAT3, is an adverse prognostic factor for diffuse large B-cell lymphoma treated with epratuzumab/R-CHOP

Clinical Trials & Observations
Mamta Gupta, Matthew J. Maurer, Linda E. Wellik, Mark E. Law, Jing Jing Han, Nazan Ozsan, Ivana N. Micallef, Ahmet Dogan, Thomas E. Witzig
Journal: Blood
Blood (2012) 120 (22): 4400–4406.
https://doi.org/10.1182/blood-2012-05-428466
Published: 2012
Includes: Supplemental data
Journal Articles

Dual mTORC1/mTORC2 inhibition diminishes Akt activation and induces Puma-dependent apoptosis in lymphoid malignancies

Mamta Gupta, Andrea E. Wahner Hendrickson, Seong Seok Yun, Jing Jing Han, Paula A. Schneider, Brian D. Koh, Mary J. Stenson, Linda E. Wellik, Jennifer C. Shing, Kevin L. Peterson, Karen S. Flatten, Allan D. Hess, B. Douglas Smith, Judith E. Karp, Sharon Barr, Thomas E. Witzig, Scott H. Kaufmann
Journal: Blood
Blood (2012) 119 (2): 476–487.
https://doi.org/10.1182/blood-2011-04-346601
Published: 2012
Includes: Supplemental data
Journal Articles

Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells

Asish K. Ghosh, Tait D. Shanafelt, Amelia Cimmino, Cristian Taccioli, Stefano Volinia, Chang-gong Liu, George A. Calin, Carlo M. Croce, Denise A. Chan, Amato J. Giaccia, Charla Secreto, Linda E. Wellik, Yean K. Lee, Debabrata Mukhopadhyay, Neil E. Kay
Journal: Blood
Blood (2009) 113 (22): 5568–5574.
https://doi.org/10.1182/blood-2008-10-185686
Published: 2009
Journal Articles

Crosstalk between Chronic Lymphocytic Leukemia (CLL) B-Cells and Marrow Stromal Cells: Implication for CLL B-Cell Activation and Survival.

Wei Ding, MD, Grzegorz S. Nowakowski, MD, Jennifer L. Abrahamzon, Linda E. Wellik, Asish K. Ghosh, PhD, Charla R. Secreto, Kay L. Medina, PhD, Tait D. Shanafelt, MD, Clive S. Zent, MD, Neil E. Kay, MD
Journal: Blood
Blood (2007) 110 (11): 337.
https://doi.org/10.1182/blood.V110.11.337.337
Published: 2007
Journal Articles

Hypoxia Inducible Factor-1α Is over Expressed in CLL B Cells Because of an Impaired Proteasome Pathway Associated with Defective Interaction with von Hippel-Landau Protein.

Yean K. Lee, Ann K. Strege, Nancy D. Bone, Linda E. Wellik, D. A. Chan, A. J. Giaccia, Debabrata Mukhopadhyay, MD, PhD, Neil E. Kay, MD
Journal: Blood
Blood (2005) 106 (11): 2115.
https://doi.org/10.1182/blood.V106.11.2115.2115
Published: 2005