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Mamatha M Reddy
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Journal Articles

Small Molecule Activators Of AMPK Block The Glycogen Production Required For Transformation Of Myeloid Leukemia Cells

Haymanti Bhanot, PhD, Mamatha M. Reddy, PhD, Atsushi Nonami, MD, PhD, Ellen L. Weisberg, PhD, Kelly Xing, Sabrina K. Salgia, John M. Asara, PhD, Richard M. Stone, MD, James D. Griffin, MD, Martin Sattler, PhD
Journal: Blood
Blood (2013) 122 (21): 1479.
https://doi.org/10.1182/blood.V122.21.1479.1479
Published: 2013
Journal Articles

BCR-ABL Transformation Requires Glycogen Synthase 1 (GYS1) Expression for Cell Growth and Increased Glycogen Production

Mamatha M. Reddy, PhD, Anagha Deshpande, PhD, Atsushi Nonami, MD, PhD, Ellen L. Weisberg, PhD, Tirumala K. Chowdary, PhD, James D. Griffin, MD, Martin Sattler, PhD
Journal: Blood
Blood (2012) 120 (21): 1673.
https://doi.org/10.1182/blood.V120.21.1673.1673
Published: 2012
Journal Articles

Rac2-MRC-cIII–generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors

Margaret Nieborowska-Skorska, Piotr K. Kopinski, Regina Ray, Grazyna Hoser, Danielle Ngaba, Sylwia Flis, Kimberly Cramer, Mamatha M. Reddy, Mateusz Koptyra, Tyrone Penserga, Eliza Glodkowska-Mrowka, Elisabeth Bolton, Tessa L. Holyoake, Connie J. Eaves, Sabine Cerny-Reiterer, Peter Valent, Andreas Hochhaus, Timothy P. Hughes, Heiko van der Kuip, Martin Sattler, Wieslaw Wiktor-Jedrzejczak, Christine Richardson, Adrienne Dorrance, Tomasz Stoklosa, David A. Williams, Tomasz Skorski
Journal: Blood
Blood (2012) 119 (18): 4253–4263.
https://doi.org/10.1182/blood-2011-10-385658
Published: 2012
Includes: Supplemental data
Journal Articles

Targeting Rac2 - Mitochondrial Respiratory Chain Complex III Signaling to Prevent Genomic Instability in Leukemia Stem and Progenitor Cells

Margaret Nieborowska-Skorska, MD, PhD, Piotr Kopinski, Regina Ray, Grazyna Hoser, PhD, Danielle Ngaba, Sylwia Flis, Kimberly Cramer, Mamatha M. Reddy, PhD, Mateusz Koptyra, PhD, Tyrone Penserga, Eliza Glodkowska-Mrowka, MD, Magdalena Ambrozek, Ilona Seferynska, MD, PhD, Joanna Niesiobedzka-Krezel, MD, Elisabeth Bolton, Artur Slupianek, PhD, Tessa L. Holyoake, PhD, FRCP, FRCPath, Connie J. Eaves, PhD, Sabine Cerny-Reiterer, D.V.M., Peter Valent, M.D., Andreas Hochhaus, MD, Timothy P. Hughes, MD, MBBS, Heiko van der Kuip, Martin Sattler, PhD, Wieslaw Wiktor-Jedrzejczak, MD, PhD, Christine Richardson, PhD, Adrienne M. Dorrance, PhD, Tomasz Stoklosa, MD, PhD, David A. Williams, MD, Tomasz Skorski, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2736.
https://doi.org/10.1182/blood.V118.21.2736.2736
Published: 2011
Journal Articles

Kinase Domain Mutations in JAK2V617F Confer Resistance to the Novel JAK2 Inhibitor Ruxolitinib

Anagha Deshpande, PhD, Mamatha M. Reddy, PhD, Georg Schade, Arghya Ray, Ph.D, Tirumala K. Chowdary, PhD, James D. Griffin, MD, Martin Sattler, PhD
Journal: Blood
Blood (2011) 118 (21): 125.
https://doi.org/10.1182/blood.V118.21.125.125
Published: 2011
Journal Articles

The JAK2V617F Oncogene, Associated with Myeloproliferative Neoplasms, Requires Expression of Inducible Phosphofructokinase/Fructose Bisphosphatase 3 for Cell Growth and Increased Metabolic Activity

Mamatha M Reddy, Margret Fernandes, James D. Griffin, Martin Sattler
Journal: Blood
Blood (2010) 116 (21): 793.
https://doi.org/10.1182/blood.V116.21.793.793
Published: 2010
Journal Articles

NADPH Oxidases Are Important Regulators of Growth and Migration in Myeloid Neoplasms.

Mamatha M. Reddy, PhD, Margret Fernandes, PhD, Ravi Salgia, MD, PhD, Ross L. Levine, MD, James D Griffin, MD, Martin Sattler, PhD
Journal: Blood
Blood (2009) 114 (22): 2190.
https://doi.org/10.1182/blood.V114.22.2190.2190
Published: 2009
Journal Articles

BCR-ABL promotes the frequency of mutagenic single-strand annealing DNA repair

Margret S. Fernandes, Mamatha M. Reddy, Jeffrey R. Gonneville, Scott C. DeRoo, Klaus Podar, James D. Griffin, David M. Weinstock, Martin Sattler
Journal: Blood
Blood (2009) 114 (9): 1813–1819.
https://doi.org/10.1182/blood-2008-07-172148
Published: 2009
Includes: Supplemental data
Journal Articles

Novel Transforming Mutations of CBL in Human Acute Myeloid Leukemia

Margret S Rodrigues, PhD, Mamatha M Reddy, Christoph Walz, MD, Ravi Salgia, Klaus Podar, Hamid Band, Andreas Reiter, MD, James D Griffin, Martin Sattler
Journal: Blood
Blood (2008) 112 (11): 2948.
https://doi.org/10.1182/blood.V112.11.2948.2948
Published: 2008
Journal Articles

The Jak2 V617F oncogene associated with myeloproliferative diseases requires a functional FERM domain for transformation and for expression of the Myc and Pim proto-oncogenes

Gerlinde Wernig, Jeffrey R. Gonneville, Brian J. Crowley, Margret S. Rodrigues, Mamatha M. Reddy, Heidi E. Hudon, Christoph Walz, Andreas Reiter, Klaus Podar, Yohan Royer, Stefan N. Constantinescu, Michael H. Tomasson, James D. Griffin, D. Gary Gilliland, Martin Sattler
Journal: Blood
Blood (2008) 111 (7): 3751–3759.
https://doi.org/10.1182/blood-2007-07-102186
Published: 2008