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Journal Articles

Crosstalk between NFAT and NFκB Signaling Regulates NK Cell Immunosurveillance

Melanie Märklin, Samuel Holzmayer, Martin R. Mueller, Helmut R. Salih

Blood (2023) 142 (Supplement 1): 1183.

https://doi.org/10.1182/blood-2023-184446

Published: 2023

Journal Articles

Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation

Blood (2022) 140 (10): 1167–1181.

https://doi.org/10.1182/blood.2022016082

Published: 2022

Includes: Supplemental data

Journal Articles

First-in-Human Phase I Dose Escalation and Expansion Study Evaluating the Fc Optimized FLT3 Antibody Flysyn in Acute Myeloid Leukemia Patients with Minimal Residual Disease

Jonas S. Heitmann, MD, Daniela Dörfel, MD, Sabine Kayser, MD, Michael Heuser, Felicitas Thol, Silke Kapp-Schwoerer, MD, Wolfgang Bethge, MD, Ludger Grosse-Hovest, Martin Steiner, Melanie Märklin, PhD, Juliane S. Walz, MD, Richard F. Schlenk, Gundram Jung, MD, Helmut R. Salih

Blood (2020) 136 (Supplement 1): 8–9.

https://doi.org/10.1182/blood-2020-139493

Published: 2020

Journal Articles

Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis

Blood (2019) 134 (21): 1847–1858.

https://doi.org/10.1182/blood.2019000185

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

Interim Results of a First in Man Study with the Fc-Optimized FLT3 Antibody Flysyn for Treatment of Acute Myeloid Leukemia with Minimal Residual Disease

Sabine Kayser, MD, Jonas S. Heitmann, MD, Daniela Dörfel, MD, Felicitas Thol, MD, Michael Heuser, MD, Melanie Märklin, PhD, Carsten Müller-Tidow, MD, Martin Steiner, Ludger Grosse-Hovest, Gundram Jung, MD, Richard F. Schlenk, MD, Helmut R. Salih, MD

Blood (2019) 134 (Supplement_1): 3928.

https://doi.org/10.1182/blood-2019-125327

Published: 2019

Journal Articles

The HLA ligandome landscape of chronic myeloid leukemia delineates novel T-cell epitopes for immunotherapy

Blood (2019) 133 (6): 550–565.

https://doi.org/10.1182/blood-2018-07-866830

Published: 2019

Includes: Supplemental data

Journal Articles

Immunocytokines with Target Cell-Restricted IL-15 Activity for Induction of NK Cell Reactivity Against Acute Myeloid Leukemia (AML)

Bastian J. Schmied, MSc, Latifa Zekri, PhD, Martin Pflügler, PhD, Melanie Märklin, PhD, Lothar Kanz, Gundram Jung, Prof., MD, Helmut R. Salih, MD

Blood (2018) 132 (Supplement 1): 731.

https://doi.org/10.1182/blood-2018-99-112485

Published: 2018

Journal Articles

The HLA Ligandome Landscape of Chronic Myeloid Leukemia Delineates Novel T-Cell Epitopes for Immunotherapy

Blood (2018) 132 (Supplement 1): 4243.

https://doi.org/10.1182/blood-2018-99-113376

Published: 2018

Journal Articles

CK2β regulates thrombopoiesis and Ca 2+ -triggered platelet activation in arterial thrombosis

Blood (2017) 130 (25): 2774–2785.

https://doi.org/10.1182/blood-2017-05-784413

Published: 2017

Includes: Multimedia, Supplemental data

Journal Articles

Lck Is a Crucial Anergy Regulator in CLL

Alexander Fuchs, Melanie Märklin, PhD, Jonas Heitmann, Felicia Truckenmüller, Sebastian Jonas Saur, MD, Manuela Ganser, Stefanie Bugl, Ursula Kohlhofer, Leticia Quintanilla-Martinez, MD, Hans-Georg Kopp, MD, Lothar Kanz, Anjana Rao, PhD, Stefan Wirths, MD, Martin R. Mueller, MD PhD

Blood (2017) 130 (Supplement 1): 3003.

https://doi.org/10.1182/blood.V130.Suppl_1.3003.3003

Published: 2017

Journal Articles

Knock-Down of the NFAT2 Long and Intermediate Isoforms Leads to CLL Acceleration

Jonas S Heitmann, MD, Melanie Märklin, PhD, Posdorowkin Anastasia, B.Sc, Alexander R Fuchs, M.Sc., Felicia M Truckenmüller, Hans-Georg Kopp, MD, Lothar Kanz, MD, Anjana Rao, PhD, Stefan Wirths, MD, Martin R Mueller, MD PhD

Blood (2016) 128 (22): 4371.

https://doi.org/10.1182/blood.V128.22.4371.4371

Published: 2016

Journal Articles

Involvement of NFAT Transcription Factors in NK Cell Reactivity

Kathrin Rothfelder, MSc, Melanie Märklin, PhD, Julia Wild, MSc, Daniela Dörfel, MD, Lothar Kanz, MD, Martin R Müller, MD PhD, Helmut R. Salih, MD

Blood (2016) 128 (22): 1344.

https://doi.org/10.1182/blood.V128.22.1344.1344

Published: 2016

Journal Articles

Loss of NFAT2 Leads to an Acceleration of Clonal Evolution in CLL

David J Müller, Melanie Märklin, PhD, Lothar Kanz, MD, Martin R Mueller, MD PhD, Stefan Wirths, MD

Blood (2016) 128 (22): 4369.

https://doi.org/10.1182/blood.V128.22.4369.4369

Published: 2016

Journal Articles

C-Cbl Regulates c-Mpl Receptor Trafficking and Its Internalization

Sebastian Jonas Saur, MD, Melanie Märklin, PhD, Manuela Ganser, Kyle Hoehn, James E David, PhD, Oliver Borst, MD, Lothar Kanz, MD, Hans-Georg Kopp, MD, Martin R Mueller, MD PhD

Blood (2015) 126 (23): 2388.

https://doi.org/10.1182/blood.V126.23.2388.2388

Published: 2015

Journal Articles

Genetic Loss of NFAT2 Leads to CLL Transformation

Melanie Märklin, PhD, Jonas Heitmann, Felicia Truckenmüller, Lothar Kanz, MD, Sebastian Jonas Saur, MD, Manuela Ganser, Bugl Stefanie, PhD, Hans-Georg Kopp, MD, Michael Haap, MD, Anjana Rao, PhD, Stefan Wirths, MD, Martin R Mueller, MD PhD

Blood (2015) 126 (23): 364.

https://doi.org/10.1182/blood.V126.23.364.364

Published: 2015

Journal Articles

NFAT2 Regulates Anergy Induction in CLL through Lck

Melanie Märklin, M. Sc., Jonas S. Heitmann, B. Sc., Alexandra Poljak, B. Sc., Stefanie Bugl, PhD, Hans-Georg Kopp, MD, Michael Haap, MD, Lothar Kanz, MD, Anjana Rao, PhD, Stefan Wirths, MD, Martin R. Müller, MD PhD

Blood (2014) 124 (21): 720.

https://doi.org/10.1182/blood.V124.21.720.720

Published: 2014

Journal Articles

Bone Marrow Derived Mesenchymal Cells Secrete Granulopoietic Cytokines upon Danger Signaling

Stefan Wirths, MD, Stefanie Bugl, PhD, Markus P. Radsak, MD, Melanie Märklin, PhD, Martin R. Müller, MD PhD, Lothar Kanz, MD, Hans-Georg Kopp, MD

Blood (2014) 124 (21): 4115.

https://doi.org/10.1182/blood.V124.21.4115.4115

Published: 2014

Journal Articles

C-CBL Is a Critical Negative Regulator of Megakaryopoesis

Sebastian J. Saur, MD, Melanie Märklin, M. Sc., Alexandra Poljak, B. Sc., Manuela Ganser, B. Sc., David E. James, PhD, Kyle Hoehn, PhD, Lothar Kanz, MD, Hans-Georg Kopp, MD, Martin R. Müller, MD PhD

Blood (2014) 124 (21): 1581.

https://doi.org/10.1182/blood.V124.21.1581.1581

Published: 2014

Journal Articles

BCR-ABL Tyrosine Kinase Inhibitors Interfere with the PI3K/Akt Signalling Pathway and Activate the Microphthalmia-Associated Transcription Factor (MITF) in Human Dendritic Cells

Daniela Doerfel, MD, Michael Gutknecht, Melanie Märklin, Lothar Kanz, MD, Helmut R. Salih, MD, Frank Gruenebach, Martin R Müller, MD PhD, Susanne M Rittig, MD

Blood (2014) 124 (21): 1416.

https://doi.org/10.1182/blood.V124.21.1416.1416

Published: 2014

Journal Articles

NFAT2 Is a Critical Regulator Of Anergy Induction In CLL

Melanie Märklin, M. Sc., Jonas S. Heitmann, B. Sc., David Worbs, B. Sc., Alexandra Poljak, B. Sc., Claude Evouna, MD, Hans-Georg Kopp, MD, Lothar Kanz, MD, Anjana Rao, PhD, Stefan Wirths, MD, Martin R Müller, MD, PhD

Blood (2013) 122 (21): 869.

https://doi.org/10.1182/blood.V122.21.869.869

Published: 2013

NARROW

Crosstalk between NFAT and NFκB Signaling Regulates NK Cell Immunosurveillance

Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation

First-in-Human Phase I Dose Escalation and Expansion Study Evaluating the Fc Optimized FLT3 Antibody Flysyn in Acute Myeloid Leukemia Patients with Minimal Residual Disease

Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis

Interim Results of a First in Man Study with the Fc-Optimized FLT3 Antibody Flysyn for Treatment of Acute Myeloid Leukemia with Minimal Residual Disease

The HLA ligandome landscape of chronic myeloid leukemia delineates novel T-cell epitopes for immunotherapy

Immunocytokines with Target Cell-Restricted IL-15 Activity for Induction of NK Cell Reactivity Against Acute Myeloid Leukemia (AML)

The HLA Ligandome Landscape of Chronic Myeloid Leukemia Delineates Novel T-Cell Epitopes for Immunotherapy

CK2β regulates thrombopoiesis and Ca 2+ -triggered platelet activation in arterial thrombosis

Lck Is a Crucial Anergy Regulator in CLL

Knock-Down of the NFAT2 Long and Intermediate Isoforms Leads to CLL Acceleration

Involvement of NFAT Transcription Factors in NK Cell Reactivity

Loss of NFAT2 Leads to an Acceleration of Clonal Evolution in CLL

C-Cbl Regulates c-Mpl Receptor Trafficking and Its Internalization

Genetic Loss of NFAT2 Leads to CLL Transformation

NFAT2 Regulates Anergy Induction in CLL through Lck

Bone Marrow Derived Mesenchymal Cells Secrete Granulopoietic Cytokines upon Danger Signaling

C-CBL Is a Critical Negative Regulator of Megakaryopoesis

BCR-ABL Tyrosine Kinase Inhibitors Interfere with the PI3K/Akt Signalling Pathway and Activate the Microphthalmia-Associated Transcription Factor (MITF) in Human Dendritic Cells

NFAT2 Is a Critical Regulator Of Anergy Induction In CLL

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American Society of Hematology

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ASH Publications

American Society of Hematology

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