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Journal Articles

Genetic Deletion or Pharmacologic Inhibition of PTPN11 Impedes the Development and Progression of Myeloproliferative Neoplasms Induced By JAK2V617F and MPLW515L Mutants

Golam Mohi, Yue Yang, Mohammad A. Sayem, Bao T. Le, Fahim Ather, Avik Dutta, Salar Abbas
Journal: Blood
Blood (2023) 142 (Supplement 1): 739.
https://doi.org/10.1182/blood-2023-190216
Published: 2023
Journal Articles

Development of the B-Cell Progenitor Niche Is Dependent on Cells Derived from the Migratory Neural Crest

Kristin Komnick, Phuong T Le, Jennifer May, Joseph Raasch, Clifford J Rosen, Karen-Sue B Carlson
Journal: Blood
Blood (2022) 140 (Supplement 1): 2898–2899.
https://doi.org/10.1182/blood-2022-167714
Published: 2022
Journal Articles

PTPN1 Deficiency Accelerates the Progression to Myelofibrosis in JAK2V617F-Driven Myeloproliferative Neoplasm

Bao T. Le, Yue Yang, Golam Mohi
Journal: Blood
Blood (2022) 140 (Supplement 1): 3855.
https://doi.org/10.1182/blood-2022-170621
Published: 2022
Journal Articles

Increased efficacy of dual proinflammatory cytokine blockade on acute GVHD while maintaining GVT effects

Brief Report
Lam T. Khuat, Logan V. Vick, Cordelia Dunai, Craig P. Collins, Shyam K. More, Catherine T. Le, Chien-Chun Steven Pai, Kevin M. Stoffel, Emanual Maverakis, Robert J. Canter, Arta M. Monjazeb, Dan L. Longo, Mehrdad Abedi, Eunju Choi, Bruce R. Blazar, Maneesh Dave, William J. Murphy
Journal: Blood
Blood (2021) 138 (24): 2583–2588.
https://doi.org/10.1182/blood.2021011216
Published: 2021
Includes: Supplemental data
Journal Articles

Inhibition of SHP2 Ameliorates JAK2V617F-Induced Myeloproliferative Neoplasms

Yue Yang, Bao T. Le, Avik Dutta, Golam Mohi
Journal: Blood
Blood (2021) 138 (Supplement 1): 1465.
https://doi.org/10.1182/blood-2021-152174
Published: 2021
Journal Articles

IL-1 Signaling Promotes Clonal Expansion and Progression of Bone Marrow Fibrosis in JAK2V617F-Induced Myeloproliferative Neoplasm

Mohammed Ferdous Ur Rahman, Yue Yang, Bao T. Le, Avik Dutta, Patrick Faughnan, Golam Mohi
Journal: Blood
Blood (2021) 138 (Supplement 1): 2540.
https://doi.org/10.1182/blood-2021-147517
Published: 2021
Journal Articles

Core-binding factor leukemia hijacks the T-cell–prone PU.1 antisense promoter

E. van der Kouwe, G. Heller, A. Czibere, J. A. Pulikkan, C. Agreiter, L. H. Castilla, R. Delwel, A. Di Ruscio, A. K. Ebralidze, M. Forte, F. Grebien, E. Heyes, L. Kazianka, J. Klinger, C. Kornauth, T. Le, K. Lind, I. A. M. Barbosa, T. Pemovska, A. Pichler, A.-S. Schmolke, C. M. Schweicker, H. Sill, W. R. Sperr, A. Spittler, S. Surapally, B. Q. Trinh, P. Valent, K. Vanura, R. S. Welner, J. Zuber, D. G. Tenen, P. B. Staber
Journal: Blood
Blood (2021) 138 (15): 1345–1358.
https://doi.org/10.1182/blood.2020008971
Published: 2021
Includes: Supplemental data
Journal Articles

Obesity-Induced Microbiome Alterations Result in Severe Gastrointestinal Graft-Versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation

Lam T. Khuat, PhD, Catherine T. Le, BS, Chien-Chun Pai, DVM, PhD, Robin Shields-Cutler, PhD, Shernan Holtan, MD, Armin Rashidi, MD PhD, Sarah Parker, MD, Dan Knights, PhD, Jesus I. Luna, PhD, Cordelia Dunai, MS, Ziming Wang, PhD, Ian R. Sturgill, MS, Kevin Stoffel, MS, Alexander A. Merleev, PhD, Emanual Maverakis, MD, Helen Raybould, PhD, Mingyi Chen, MD PhD, Robert J. Canter, MD, Arta M. Monjazeb, MD PhD, James L. M. Ferrara, MDDSc, John E. Levine, MDMS, Dan L. Longo, MD, Mehrdad Abedi, MD, Bruce R. Blazar, MD, William J. Murphy, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1922.
https://doi.org/10.1182/blood-2019-127743
Published: 2019
Journal Articles

CXCL1 regulates neutrophil homeostasis in pneumonia-derived sepsis caused by Streptococcus pneumoniae serotype 3

Sagar Paudel, Pankaj Baral, Laxman Ghimire, Scott Bergeron, Liliang Jin, Joseph A. DeCorte, John T. Le, Shanshan Cai, Samithamby Jeyaseelan
Journal: Blood
Blood (2019) 133 (12): 1335–1345.
https://doi.org/10.1182/blood-2018-10-878082
Published: 2019
Includes: Supplemental data
Journal Articles

Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma

Michelle M. McDonald, Michaela R. Reagan, Scott E. Youlten, Sindhu T. Mohanty, Anja Seckinger, Rachael L. Terry, Jessica A. Pettitt, Marija K. Simic, Tegan L. Cheng, Alyson Morse, Lawrence M. T. Le, David Abi-Hanna, Ina Kramer, Carolyne Falank, Heather Fairfield, Irene M. Ghobrial, Paul A. Baldock, David G. Little, Michaela Kneissel, Karin Vanderkerken, J. H. Duncan Bassett, Graham R. Williams, Babatunde O. Oyajobi, Dirk Hose, Tri G. Phan, Peter I. Croucher
Journal: Blood
Blood (2017) 129 (26): 3452–3464.
https://doi.org/10.1182/blood-2017-03-773341
Published: 2017
Includes: Supplemental data
Journal Articles

Sustained Elevation of Adenosine-ADORA2B Signaling Promotes Chronic Pain through Neuro-Immune Interaction in Sickle Cell Disease

Morayo G. Adebiyi, BS, Xia Hu, MD, Jialie Luo, PhD, Kaiqi Sun, BS, Thanh-Thuy T. Le, MD PhD, Yujin Zhang, MD, Hongyu Wu, PhD, Hong Liu, MD, Aji Huang, BS, MS, Rodney E. Kellems, PhD, Michael R. Blackburn, PhD, Edgar T. Walters, PhD, Hongzhen Hu, PhD, Yang Xia, MD PhD
Journal: Blood
Blood (2015) 126 (23): 974.
https://doi.org/10.1182/blood.V126.23.974.974
Published: 2015
Journal Articles

Overexpression of Foxn1 attenuates age-associated thymic involution and prevents the expansion of peripheral CD4 memory T cells

Erin C. Zook, Paulette A. Krishack, Shubin Zhang, Nancy J. Zeleznik-Le, Anthony B. Firulli, Pamela L. Witte, Phong T. Le
Journal: Blood
Blood (2011) 118 (22): 5723–5731.
https://doi.org/10.1182/blood-2011-03-342097
Published: 2011
Includes: Supplemental data
Journal Articles

In vitro requirement for periostin in B lymphopoiesis

Basile T. Siewe, Susan L. Kalis, Phong T. Le, Pamela L. Witte, Sangdun Choi, Simon J. Conway, Laurel Druschitz, Katherine L. Knight
Journal: Blood
Blood (2011) 117 (14): 3770–3779.
https://doi.org/10.1182/blood-2010-08-301119
Published: 2011
Includes: Supplemental data
Journal Articles

Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia

Clinical Trials & Observations
Sarah Cooley, Daniel J. Weisdorf, Lisbeth A. Guethlein, John P. Klein, Tao Wang, Chap T. Le, Steven G. E. Marsh, Daniel Geraghty, Stephen Spellman, Michael D. Haagenson, Martha Ladner, Elizabeth Trachtenberg, Peter Parham, Jeffrey S. Miller
Journal: Blood
Blood (2010) 116 (14): 2411–2419.
https://doi.org/10.1182/blood-2010-05-283051
Published: 2010
Journal Articles

Selection of Donors with Favorable KIR B Genotypes for Unrelated Hematopoietic Cell Transplantation Results in Superior Relapse Protection and Better Relapse-Free Survival for Patients with AML.

Sarah Cooley, Lisbeth Guethlein, PhD, Elizabeth Trachtenberg, PhD, Martha Ladner, Xianghua Luo, Chap T Le, Tao Wang, PhD, John P. Klein, PhD, Steven G.E. Marsh, PhD, Stephen Spellman, Michael D Haagenson, MS, Daniel J. Weisdorf, MD, Peter Parham, Jeffrey S. Miller
Journal: Blood
Blood (2009) 114 (22): 665.
https://doi.org/10.1182/blood.V114.22.665.665
Published: 2009
Journal Articles

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia

Sarah Cooley, Elizabeth Trachtenberg, Tracy L. Bergemann, Koy Saeteurn, John Klein, Chap T. Le, Steven G. E. Marsh, Lisbeth A. Guethlein, Peter Parham, Jeffrey S. Miller, Daniel J. Weisdorf
Journal: Blood
Blood (2009) 113 (3): 726–732.
https://doi.org/10.1182/blood-2008-07-171926
Published: 2009
Includes: Supplemental data
Journal Articles

Comparative Assessment of Weighting Comorbidities in the Hematopoietic Cell Transplantation (HCT) Specific Comorbidity Index (HCT-CI)

Todd E DeFor, MS, Navneet S. Majhail, MD, MS, Claudio Brunstein, MD, PhD, Daniel J. Weisdorf, MD, Chap T Le, PhD
Journal: Blood
Blood (2008) 112 (11): 798.
https://doi.org/10.1182/blood.V112.11.798.798
Published: 2008
Journal Articles

Mutations That Cooperate with Nf1 Inactivation in Leukemogenesis Influence Therapeutic Response to MEK Inhibition.

Jennifer O. Lauchle, MD, Doan T. Le, MD, Doris Kim, Keiko Akagi, PhD, Matthew F. Gorman, MD, Mary Tran, Judith Sebolt-Leopold, PhD, Linda Wolff, PhD, Luis F. Parada, PhD, Nancy Jenkins, PhD, Neal Copeland, PhD, Kevin M. Shannon, MD
Journal: Blood
Blood (2007) 110 (11): 594.
https://doi.org/10.1182/blood.V110.11.594.594
Published: 2007
Journal Articles

Inability of memory T cells to induce graft-versus-host disease is a result of an abortive alloresponse

Benny J. Chen, Divino Deoliveira, Xiuyu Cui, Ngocdiep T. Le, Jessica Son, John F. Whitesides, Nelson J. Chao
Journal: Blood
Blood (2006) 109 (7): 3115–3123.
https://doi.org/10.1182/blood-2006-04-016410
Published: 2006
Journal Articles

β common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice

Andrew Kim, Kelly Morgan, Diane E. Hasz, Stephen M. Wiesner, Jennifer O. Lauchle, Jennifer L. Geurts, Miechaleen D. Diers, Doan T. Le, Scott C. Kogan, Luis F. Parada, Kevin Shannon, David A. Largaespada
Journal: Blood
Blood (2006) 109 (4): 1687–1691.
https://doi.org/10.1182/blood-2006-05-025395
Published: 2006
Includes: Supplemental data