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Wendy Béguelin
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Journal Articles

Inhibition of EZH2 Improves CART19 Immunotherapy By Reprogramming Lymphoma Tumor Cells and Enhancing T-Cell Functionality

Patrizia Porazzi, Yusuke Isshiki, Guido Ghilardi, Siena Nason, Ziqi Yang, Alberto Carturan, Linhui Chen, Yunlin Zhang, Ruchi P. Patel, Puneeth Guruprasad, Ositadimma Ugwuanyi, Ivan J Cohen, Stephen J Schuster, Ari M Melnick, Wendy Béguelin, Marco Ruella
Journal: Blood
Blood (2023) 142 (Supplement 1): 1018.
https://doi.org/10.1182/blood-2023-182440
Published: 2023
Journal Articles

Cooperative Super-Enhancer Inactivation through Loss of Crebbp and KMT2D Skews B Cell Fate Decisions and Yields T Cell-Depleted Lymphomas

Jie Li, Christopher Chin, Hsia-Yuan Ying, Cem Meydan, Matthew Teater, Min Xia, Pedro Farinha, Katsuyoshi Takata, Chi-Shuen Chu, Martin A Rivas, Amy Chadburn, Christian Steidl, David W. Scott, Robert G. Roeder, Christopher Mason, Wendy Béguelin, Ari M Melnick
Journal: Blood
Blood (2023) 142 (Supplement 1): 2776.
https://doi.org/10.1182/blood-2023-174501
Published: 2023
Journal Articles

EZH2 Inhibitors Enhance CART Cell Quality, Efficacy, In Vivo Homing, Tumor Cell Binding and Killing of Fully Syngeneic Primary B Cell Lymphomas, As Well As Reprogramming Lymphoma Cells to a Highly Immunogenic and T Cell Adherent Phenotype

Yusuke Isshiki, Patrizia Porazzi, Xi Chen, Matthew Teater, Ioannis Karagiannidis, Henna S. Nam, Ari M Melnick, Marco Ruella, Wendy Béguelin
Journal: Blood
Blood (2023) 142 (Supplement 1): 432.
https://doi.org/10.1182/blood-2023-190610
Published: 2023
Journal Articles

T-Cell Signaling Mediates the Epigenetic Priming of Germinal Center B-Cell Plasticity and Stem Functionality

Laurianne Scourzic, Franco Izzo, Lucretia Cucereavii, Matthew Teater, Alexander Polyzos, Christopher Chin, Coraline Mlynarczyk, Ioanna Tsialta, Robert M Myers, Wendy Béguelin, Matthias Stadtfeld, Zhengming Chen, Dan A. Landau, Ari M Melnick, Eftychia Apostolou
Journal: Blood
Blood (2023) 142 (Supplement 1): 2767.
https://doi.org/10.1182/blood-2023-190437
Published: 2023
Journal Articles

Development of Syngeneic Murine Cell Lines of Germinal Center-Derived B-Cell Lymphomas

Henna S. Nam, Yusuke Isshiki, Min Xia, Sanket Shah, Meng Li, Ioannis Karagiannidis, Matthew Teater, Ari M Melnick, Wendy Béguelin
Journal: Blood
Blood (2023) 142 (Supplement 1): 4365.
https://doi.org/10.1182/blood-2023-186686
Published: 2023
Journal Articles

Qpctl Inhibition, By Targeting the Inflammatory Tumor Microenvironment, Constitutes a Novel Therapeutic Approach for Diffuse Large B-Cell Lymphoma

Nicolas Di Siervi, Jasper Mullender, María Victoria Revuelta, Nahuel Zamponi, Eloisi Caldas-Lopes, Yusuke Isshiki, Wendy Béguelin, Marcel Scheepstra, Bastiaan Evers, Jens Wuerthner, Leandro Cerchietti
Journal: Blood
Blood (2023) 142 (Supplement 1): 49.
https://doi.org/10.1182/blood-2023-181264
Published: 2023