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Journal Articles

STAT1-mediated interferon signatures are associated with preclinical JAK inhibitor sensitivity in T-ALL

Blood (2025) 145 (23): 2793–2798.

https://doi.org/10.1182/blood.2025028566

Published: 2025

Includes: Supplemental data

Journal Articles

Cdc73 protects Notch-induced T-cell leukemia cells from DNA damage and mitochondrial stress

Blood (2023) 142 (25): 2159–2174.

https://doi.org/10.1182/blood.2023020144

Published: 2023

Includes: Supplemental data

Journal Articles

Polymerase-Associated Factor Complex (PAFc) Protects Notch-Induced Leukemia Cells from DNA Damage and Mitochondrial Stress

Ashley Melnick, Anna McCarter, Shannon Liang, Nicole Dean, Elizabeth Choe, Nicholas Kunnath, Brian Magnuson, Karena Lin, Qing Wang, Surinder Kumar, David Lombard, Russell J.H. Ryan, Mats Ljungman, Mark Y Chiang

Blood (2022) 140 (Supplement 1): 1005–1006.

https://doi.org/10.1182/blood-2022-157573

Published: 2022

Journal Articles

Native Stem Cell Transcriptional Circuits in Normal and Malignant Early-Stage T Cells

Mark Y Chiang, Qing Wang, Carea Mullin, Elizabeth Choe, Nicole Dean, Fatema Akter, Siyi Chen, Ashley Melnick, Anna McCarter, Rohan Kodgule, Raghu Vannam, Christopher J. Ott, Russell J.H. Ryan

Blood (2022) 140 (Supplement 1): 1003–1004.

https://doi.org/10.1182/blood-2022-156266

Published: 2022

Journal Articles

Firing up chromatin to forge T-ALL

Mark Y. Chiang

Blood (2022) 139 (16): 2418–2420.

https://doi.org/10.1182/blood.2021015364

Published: 2022

Journal Articles

Tearing ATL apart to find HTLV’s sinister plans

Mark Y. Chiang

Blood (2020) 135 (12): 887–889.

https://doi.org/10.1182/blood.2020004998

Published: 2020

Journal Articles

Finding ARIEL under the sea of T-ALL circuits

Mark Y. Chiang

Blood (2019) 134 (3): 219–221.

https://doi.org/10.1182/blood.2019001584

Published: 2019

Journal Articles

Ets1 Enhances Context-Dependent Notch1 Activity in T-Cell Leukemia

Anna McCarter, BS, Ran Yan, Amparo Serna Alarcon, Catherine Chang, Erin Kim, Cher Sha, Yiran Liu, Qing Wang, PhD, Luke F. Peterson, PhD, Rork Kuick, Russell Ryan, MD, Moshe Talpaz, MD, Linda Samuelson, PhD, Michael Ostrowski, PhD, Mark Y Chiang, MD PhD

Blood (2018) 132 (Supplement 1): 2595.

https://doi.org/10.1182/blood-2018-99-111376

Published: 2018

Journal Articles

Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development

Qing Wang, Ran Yan, Nancy Pinnell, Anna C. McCarter, Yeonjoo Oh, Yiran Liu, Cher Sha, Noah F. Garber, Yitong Chen, Qingqing Wu, Chia-Jui Ku, Ivy Tran, Amparo Serna Alarcon, Rork Kuick, James Douglas Engel, Ivan Maillard, Tomasz Cierpicki, Mark Y. Chiang

Blood (2018) 132 (12): 1279–1292.

https://doi.org/10.1182/blood-2018-02-835850

Published: 2018

Includes: Supplemental data

Journal Articles

High selective pressure for Notch1 mutations that induce Myc in T-cell acute lymphoblastic leukemia

Mark Y. Chiang, Qing Wang, Anna C. Gormley, Sarah J. Stein, Lanwei Xu, Olga Shestova, Jon C. Aster, Warren S. Pear

Blood (2016) 128 (18): 2229–2240.

https://doi.org/10.1182/blood-2016-01-692855

Published: 2016

Includes: Supplemental data

Journal Articles

Phase 2 Study of Monotherapy Galunisertib (LY2157299 Monohydrate) in Very Low-, Low-, and Intermediate-Risk Patients with Myelodysplastic Syndromes

David Valcarcel, MD PhD, Amit Verma, MD, Uwe Platzbecker, MD, Valeria Santini, MD, Aristoteles Giagounidis, MD, María Díez-Campelo, MD PhD, Jan Janssen, MD, Richard F. Schlenk, MD, Gianluca Gaidano, MD PhD, Jaime Perez de Oteyza, MD, Ann L Cleverly, MD, Alan Y Chiang, PhD, Michael Lahn, MD, Durisala Desiaih, PhD, Susan C. Guba, MD, Alan F. List, MD, Rami S. Komrokji, MD

Blood (2015) 126 (23): 1669.

https://doi.org/10.1182/blood.V126.23.1669.1669

Published: 2015

Journal Articles

Direct Coregulation of Notch1 By Zmiz1 in T-Cell Development and Leukemia

Nancy Pinnell, Ran Yan, Hyoje Cho, PhD, Paula Jeon, Theresa Keeley, Jordan McHugh, Yiran Liu, Kojo S.J. Elenitoba-Johnson, MD, Ivan Maillard, MD PhD, Linda C. Samuelson, PhD, Tomasz Cierpicki, PhD, Mark Y. Chiang, MD PhD

Blood (2014) 124 (21): 55.

https://doi.org/10.1182/blood.V124.21.55.55

Published: 2014

Journal Articles

Revascularization Strategies and In-Hospital Outcomes In Acute Coronary Syndromes (ACS) Complicated By Von Willebrand Disease (VWD)

Patrick F. Fogarty, M.D., William H. Matthai, Jr., M.D., Anne Boccuti, B.A., Rolando Vega, B.A., Elaine Y Chiang, M.D., Phyllis A. Gimotty, Ph.D.

Blood (2013) 122 (21): 2354.

https://doi.org/10.1182/blood.V122.21.2354.2354

Published: 2013

Journal Articles

Divergent effects of supraphysiologic Notch signals on leukemia stem cells and hematopoietic stem cells

Mark Y. Chiang, Olga Shestova, Lanwei Xu, Jon C. Aster, Warren S. Pear

Blood (2013) 121 (6): 905–917.

https://doi.org/10.1182/blood-2012-03-416503

Published: 2013

Includes: Supplemental data

Journal Articles

The Pias-Like Coactivator ZMIZ1 Drives C-MYC Induction in Collaboration with NOTCH1 in T-Cell Acute Lymphoblastic Leukemia.

Margaret Decker, Choi Li, Lesley A Rakowski, Tomasz Cierpicki, PhD, Mark Y. Chiang, MD, PhD

Blood (2012) 120 (21): 2380.

https://doi.org/10.1182/blood.V120.21.2380.2380

Published: 2012

Journal Articles

ZMIZ1 Collaborates with NOTCH1 During Induction and Maintenance of T-Cell Acute Lymphoblastic Leukemia

Lesley A Rakowski, Derek D Garagiola, Sarah C Caruso, Mark Y. Chiang, MD, PhD

Blood (2011) 118 (21): 75.

https://doi.org/10.1182/blood.V118.21.75.75

Published: 2011

Journal Articles

Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1

Todd D. Ashworth, Warren S. Pear, Mark Y. Chiang, Stephen C. Blacklow, Jérôme Mastio, Lanwei Xu, Michelle Kelliher, Philippe Kastner, Susan Chan, Jon C. Aster

Blood (2010) 116 (25): 5455–5464.

https://doi.org/10.1182/blood-2010-05-286328

Published: 2010

Includes: Supplemental data

Journal Articles

Transient Responses to Notch and Tlx1/Hox11 Inhibition In T-Cell Acute Lymphoblastic Leukemia/Lymphoma.

Erica A. Lehotzky, B.S., Mark Y. Chiang, MD, PhD

Blood (2010) 116 (21): 1026.

https://doi.org/10.1182/blood.V116.21.1026.1026

Published: 2010

Journal Articles

C-Myc, but Not Akt, Can Substitute for Notch in Lymphomagenesis.

Mark Y Chiang, MD, PhD, M. Eden Childs, B.A., Candice Romany, Olga Shestova, Ph.D., Jon Aster, MD, PhD, Warren S. Pear, MD, PhD

Blood (2009) 114 (22): 7.

https://doi.org/10.1182/blood.V114.22.7.7

Published: 2009

Journal Articles

Divergent Effects of Notch Signaling On Leukemia Stem Cells and Hematopoietic Stem Cells.

Mark Y Chiang, MD, PhD, Olga Shestova, Ph.D., M. Eden Childs, B.A., Candice Romany, Jon Aster, MD, PhD, Warren S. Pear, MD, PhD

Blood (2009) 114 (22): 395.

https://doi.org/10.1182/blood.V114.22.395.395

Published: 2009

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STAT1-mediated interferon signatures are associated with preclinical JAK inhibitor sensitivity in T-ALL

Cdc73 protects Notch-induced T-cell leukemia cells from DNA damage and mitochondrial stress

Polymerase-Associated Factor Complex (PAFc) Protects Notch-Induced Leukemia Cells from DNA Damage and Mitochondrial Stress

Native Stem Cell Transcriptional Circuits in Normal and Malignant Early-Stage T Cells

Firing up chromatin to forge T-ALL

Tearing ATL apart to find HTLV’s sinister plans

Finding ARIEL under the sea of T-ALL circuits

Ets1 Enhances Context-Dependent Notch1 Activity in T-Cell Leukemia

Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development

High selective pressure for Notch1 mutations that induce Myc in T-cell acute lymphoblastic leukemia

Phase 2 Study of Monotherapy Galunisertib (LY2157299 Monohydrate) in Very Low-, Low-, and Intermediate-Risk Patients with Myelodysplastic Syndromes

Direct Coregulation of Notch1 By Zmiz1 in T-Cell Development and Leukemia

Revascularization Strategies and In-Hospital Outcomes In Acute Coronary Syndromes (ACS) Complicated By Von Willebrand Disease (VWD)

Divergent effects of supraphysiologic Notch signals on leukemia stem cells and hematopoietic stem cells

The Pias-Like Coactivator ZMIZ1 Drives C-MYC Induction in Collaboration with NOTCH1 in T-Cell Acute Lymphoblastic Leukemia.

ZMIZ1 Collaborates with NOTCH1 During Induction and Maintenance of T-Cell Acute Lymphoblastic Leukemia

Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1

Transient Responses to Notch and Tlx1/Hox11 Inhibition In T-Cell Acute Lymphoblastic Leukemia/Lymphoma.

C-Myc, but Not Akt, Can Substitute for Notch in Lymphomagenesis.

Divergent Effects of Notch Signaling On Leukemia Stem Cells and Hematopoietic Stem Cells.

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American Society of Hematology

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