Page 1 | Search Results | Blood | American Society of Hematology

1-17 of 17

Sort by

Sort Order Select

Journal Articles

Progression signature underlies clonal evolution and dissemination of multiple myeloma

Yu Jia Shen, Yuji Mishima, Jiantao Shi, Romanos Sklavenitis-Pistofidis, Robert A. Redd, Michele Moschetta, Salomon Manier, Aldo M. Roccaro, Antonio Sacco, Yu-Tzu Tai, Francois Mercier, Yawara Kawano, Nang Kham Su, Brianna Berrios, John G. Doench, David E. Root, Franziska Michor, David T. Scadden, Irene M. Ghobrial

Blood (2021) 137 (17): 2360–2372.

https://doi.org/10.1182/blood.2020005885

Published: 2021

Includes: Supplemental data

Journal Articles

The High Mobility Group A1 Chromatin Regulator Is Required for Pathologic Megakaryocyte Development and Progression to Myelofibrosis in JAK2V617F Murine Models

Alison R. Moliterno, MD, Donna Marie Williams, PhD, Liping Li, MD PhD, Lingling Xian, MD PhD, Li Luo, PhD, Amy S. Duffield, MD PhD, Ophelia Rogers, Jerry L. Spivak, MD, Linda Resar, MD

Blood (2019) 134 (Supplement_1): 472.

https://doi.org/10.1182/blood-2019-131432

Published: 2019

Journal Articles

High Mobility Group A1 Chromatin Regulators: Key Epigenetic Switches and Therapeutic Targets Required for Leukemic Transformation in JAK2 Mutant MPN

Liping Li, MD PhD, Wenyan Lu, PhD, Alison R. Moliterno, MD, Lingling Xian, MD PhD, Joseph Kim, BS, Ophelia Rogers, Jerry L. Spivak, MD, Linda Resar, MD

Blood (2019) 134 (Supplement_1): 1680.

https://doi.org/10.1182/blood-2019-130262

Published: 2019

Journal Articles

High Mobility Group A1 Chromatin Regulators Function As Critical Drivers of Leukemogenesis in Preclinical Models of Relapsed, Pediatric B-Cell ALL

Liping Li, MD PhD, Katharina Hayer, Lingling Xian, MD PhD, Li Luo, PhD, Leslie Cope, Andrei Thomas-Tikhonenko, PhD, Linda Resar, MD

Blood (2019) 134 (Supplement_1): 3946.

https://doi.org/10.1182/blood-2019-130261

Published: 2019

Journal Articles

High Mobility Group A1 Chromatin Remodeling Proteins Amplify Inflammatory Networks to Drive Leukemic Transformation in Chronic Myeloproliferative Neoplasia in Humans and JAK2 V617F Transgenic Mouse Models

Linda Resar, MD, Donna Marie Williams, PhD, Lingling Xian, MD PhD, Wenyan Lu, PhD, Briyana Chisholm, BS, Li Luo, PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2018) 132 (Supplement 1): 102.

https://doi.org/10.1182/blood-2018-99-119549

Published: 2018

Journal Articles

Deciphering Clonal Evolution and Dissemination of Multiple Myeloma Cells In Vivo

Blood (2018) 132 (Supplement 1): 55.

https://doi.org/10.1182/blood-2018-99-113916

Published: 2018

Journal Articles

High Mobility Group A1 Chromatin Remodeling Proteins: Potential Therapeutic Targets Involved in Polycythemia Vera Transformation to Acute Leukemia in Humans and JAK2 V617F Transgenic Mouse Models

Linda Resar, MD, Donna Marie Williams, PhD, Lingling Xian, MD PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2017) 130 (Supplement 1): 489.

https://doi.org/10.1182/blood.V130.Suppl_1.489.489

Published: 2017

Journal Articles

High Mobility Group A1 Chromatin Remodeling Protein Regulates Self-Renewal, Niche Formation, and Regenerative Function in Adult Stem Cells through Wnt/β-Catenin Signaling

Linda Resar, MD, Lingling Xian, MD PhD, Tait Huso, Amy Belton, PhDBSc, Leslie Cope, PhDBSc, David Huso, DVM, PhD

Blood (2016) 128 (22): 2647.

https://doi.org/10.1182/blood.V128.22.2647.2647

Published: 2016

Journal Articles

High Mobility Group A1/2 Chromatin Remodeling Proteins Associate with Polycythemia Vera Transformation to Acute Leukemia in Humans and a JAK2 V617F Transgenic Mouse Model

Linda Resar, MD, Donna Marie Williams, PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Lingling Xian, MD PhD, Jerry L. Spivak, MD, Alison R Moliterno, MD

Blood (2016) 128 (22): 1958.

https://doi.org/10.1182/blood.V128.22.1958.1958

Published: 2016

Journal Articles

A Novel Feed-Forward Loop Involving the High Mobility Group A1 (HMGA1) Chromatin Remodeling Protein and cMYC in Acute Myeloid Leukemia Is Targeted By JQ1

Linda Resar, MD, Stuart A Rushworth, PhDBSc, Lingling Xian, MD PhD, Kristian Bowles, MB BS, PhD FRCP, FRCPath

Blood (2015) 126 (23): 2466.

https://doi.org/10.1182/blood.V126.23.2466.2466

Published: 2015

Journal Articles

High Mobility Group A1 (HMGA1) Chromatin Remodeling Protein Mediates Crosstalk Between Acute Myeloid Leukemia Blasts & the Tumor Microenvironment

Stuart A Rushworth, PhD, Lyubov Zaitseva, PhD, Lingling Xian, MD PhD, Kristian M Bowles, MB BS, PhD, Linda M. S. Resar, MD

Blood (2014) 124 (21): 3564.

https://doi.org/10.1182/blood.V124.21.3564.3564

Published: 2014

Journal Articles

HMGA1, a Factor Enriched in Hematopoietic Stem Cells, Embryonic Stem Cells, and Hematologic Malignancy, Enhances Cellular Reprogramming to a Pluripotent Stem-Like Cell.

Linda Resar, M.D., Sandeep N Shah, Ph.D., Candace Kerr, Ph.D., Leslie Cope, Ph.D., Elias Zambidis, M.D., Ph.D., Amy Belton, Ph.D., David L. Huso, D.V.M., Ph.D.

Blood (2012) 120 (21): 2323.

https://doi.org/10.1182/blood.V120.21.2323.2323

Published: 2012

Journal Articles

HMGA1 Drives Inflammatory Pathways, Cell Cycle Progression, and Embryonic Stem Cell Genes During Leukemic Transformation

Andrew Schuldenfrei, Amy Belton, Ph.D., Jeanne Kowalski, PhD, C. Conover Talbot, Jr., B.S., Francescopaolo Di Cello, Weijie Poh, Hua-Ling Tsai, MS, Sandeep N Shah, Tait Huso, David Huso, D.V.M., Ph.D., Linda Resar, MD

Blood (2011) 118 (21): 1371.

https://doi.org/10.1182/blood.V118.21.1371.1371

Published: 2011

Journal Articles

Induction of Senescence by Doxorubicin Is Associated with Upregulated Mir-375 and Induction of Autophagy In CML Cell Line K562

Ming-Yu Yang, PhD, Wen-Chi Yang, MD, Pai-Mei Lin, PhD, Jui-Feng Hsu, MD, Hui-Hua Hsiao, MD, Yi-Chang Liu, MD, Hui-Jen Tsai, MD, Sheng-Fung Lin, MD

Blood (2010) 116 (21): 1843.

https://doi.org/10.1182/blood.V116.21.1843.1843

Published: 2010

Journal Articles

The HMGA1a-STAT3 axis: an “Achilles Heel” for Hematopoietic Malignancies Overexpressing HMGA1a?

Linda Resar, MD, Joelle Hillion, Ph.D., Surajit Dhara, Ph.D., Takita Felder Sumter, Ph.D., Mita Mukherjee, Ph.D., Francescopaolo Di Cello, Ph.D., Amy Belton, Ph.D., James Turkson, Ph.D., Souyma Jaganathan, Ph.D., Linzhao Cheng, Ph.D., Zhaohui Ye, B.S., Yingwei Lin, MD, PhD, Peter D. Aplan, MD, Richard Jove, Jeanne Kowalski, Kelsey Wertzler, B.S., Ray Reeves, Ph.D., Ossama Elbahlouh, M.D., Raka Bhattacharya, Ph.D.

Blood (2008) 112 (11): 3810.

https://doi.org/10.1182/blood.V112.11.3810.3810

Published: 2008

Journal Articles

Inhibition of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-ALL after Blocking Remote 3′-BCL11B Enhancer Sequences with Matching DNA Oligos Reveals Coregulation by PU.1 and HMGA1.

Stefan Nagel, PhD, Michaela Scherr, PhD, Alexander Kel, PhD, Klaus Hornischer, PhD, Gregory E. Crawford, PhD, Maren Kaufmann, Corinna Meyer, Hans G. Drexler, MD, Roderick A.F. MacLeod, PhD

Blood (2006) 108 (11): 2212.

https://doi.org/10.1182/blood.V108.11.2212.2212

Published: 2006

Journal Articles

STAT3: A Direct HMGA1 Gene Target Important in Lymphoid Malignancy.

Linda Resar, MD, Surajit Dhara, Ph.D., Takita Felder Sumter, Ph.D., Mita Mukherjee, Ph.D., James Turkson, Ph.D., Rich Jove, Ph.D., Ossama Elbahloul, M.D., Peter Aplan, M.D., Ying-Wei Lin, M.D., Ph.D., Raka Bhattacharya, Ph.D.

Blood (2006) 108 (11): 2222.

https://doi.org/10.1182/blood.V108.11.2222.2222

Published: 2006

NARROW

Progression signature underlies clonal evolution and dissemination of multiple myeloma

The High Mobility Group A1 Chromatin Regulator Is Required for Pathologic Megakaryocyte Development and Progression to Myelofibrosis in JAK2V617F Murine Models

High Mobility Group A1 Chromatin Regulators: Key Epigenetic Switches and Therapeutic Targets Required for Leukemic Transformation in JAK2 Mutant MPN

High Mobility Group A1 Chromatin Regulators Function As Critical Drivers of Leukemogenesis in Preclinical Models of Relapsed, Pediatric B-Cell ALL

High Mobility Group A1 Chromatin Remodeling Proteins Amplify Inflammatory Networks to Drive Leukemic Transformation in Chronic Myeloproliferative Neoplasia in Humans and JAK2 V617F Transgenic Mouse Models

Deciphering Clonal Evolution and Dissemination of Multiple Myeloma Cells In Vivo

High Mobility Group A1 Chromatin Remodeling Proteins: Potential Therapeutic Targets Involved in Polycythemia Vera Transformation to Acute Leukemia in Humans and JAK2 V617F Transgenic Mouse Models

High Mobility Group A1 Chromatin Remodeling Protein Regulates Self-Renewal, Niche Formation, and Regenerative Function in Adult Stem Cells through Wnt/β-Catenin Signaling

High Mobility Group A1/2 Chromatin Remodeling Proteins Associate with Polycythemia Vera Transformation to Acute Leukemia in Humans and a JAK2 V617F Transgenic Mouse Model

A Novel Feed-Forward Loop Involving the High Mobility Group A1 (HMGA1) Chromatin Remodeling Protein and cMYC in Acute Myeloid Leukemia Is Targeted By JQ1

High Mobility Group A1 (HMGA1) Chromatin Remodeling Protein Mediates Crosstalk Between Acute Myeloid Leukemia Blasts & the Tumor Microenvironment

HMGA1, a Factor Enriched in Hematopoietic Stem Cells, Embryonic Stem Cells, and Hematologic Malignancy, Enhances Cellular Reprogramming to a Pluripotent Stem-Like Cell.

HMGA1 Drives Inflammatory Pathways, Cell Cycle Progression, and Embryonic Stem Cell Genes During Leukemic Transformation

Induction of Senescence by Doxorubicin Is Associated with Upregulated Mir-375 and Induction of Autophagy In CML Cell Line K562

The HMGA1a-STAT3 axis: an “Achilles Heel” for Hematopoietic Malignancies Overexpressing HMGA1a?

Inhibition of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-ALL after Blocking Remote 3′-BCL11B Enhancer Sequences with Matching DNA Oligos Reveals Coregulation by PU.1 and HMGA1.

STAT3: A Direct HMGA1 Gene Target Important in Lymphoid Malignancy.

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only