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Journal Articles

Disease Modeling of Severe Congenital Neutropenia Using CRISPR/Cas9 Gene Correction or Knockout of ELANE in Patients Derived Induced Pluripotent Stem Cells

Masoud Nasri, MSc, Benjamin Dannenmann, Perihan Mir, Malte U Ritter, Diana Amend, Yun Xu, Maksim Klimiankou, Cornelia Zeidler, Karl Welte, Julia Skokowa, MD PhD

Blood (2019) 134 (Supplement_1): 434.

https://doi.org/10.1182/blood-2019-129991

Published: 2019

Journal Articles

A Phase 2 Study of the Dual SYK/JAK Inhibitor Cerdulatinib Demonstrates Good Tolerability and Clinical Response in Relapsed/Refractory Peripheral T-Cell Lymphoma and Cutaneous T-Cell Lymphoma

Steven M. Horwitz, MD, Tatyana A. Feldman, MD, Brian T. Hess, MD, Michael S. Khodadoust, MD PhD, Youn H. Kim, MD, Javier Munoz, MD MS, FACP, Manish R. Patel, MD, Tycel J. Phillips, MD, Stephen D. Smith, MD, Sonali M. Smith, MD, Ryan A. Wilcox, MD PhD, Matt R. Birrell, Janet M. Leeds, PhD, Pamela B. Conley, PhD, Glenn C. Michelson, MD, Gregory P. Coffey, PhD, John T. Curnutte, MD PhD, Paul A. Hamlin, MD

Blood (2019) 134 (Supplement_1): 466.

https://doi.org/10.1182/blood-2019-123986

Published: 2019

Journal Articles

CLL B Cells Develop Resistance to Ibrutinib By Reinvigorating the IL-4R - IL-4 Axis Blocked By Bruton's Tyrosine Kinase Inhibitors Including Acalabrutinib and Zanubrutinib

Shih-Shih Chen, PhD, Constantine S. Tam, MBBS (Hons), MD, Alan G. Ramsay, BSc,MSc,PhD, Priyadarshini Ravichandran, Natalia C. Couto-Francisco, Michael Ibrahim, Gerardo Ferrer, PhD, Jonathan E. Kolitz, MD, Steven L. Allen, MD, He Zhou, Jacqueline C Barrientos, MD, Kanti R Rai, MD, Nicholas Chiorazzi, MD

Blood (2019) 134 (Supplement_1): 477.

https://doi.org/10.1182/blood-2019-127255

Published: 2019

Journal Articles

Third Party Type 2 Innate Lymphoid Cells Treat and Prevent GI Tract Acute GvHD

Danny W. Bruce, PhD, Oleg Kolupaev, PhD, Hemamalini Bommiasamy, PhD, Heather Stefanski, MD PhD, Bruce R. Blazar, MD, James M. Coghill, Jr., MD, Jonathan S Serody, MD

Blood (2019) 134 (Supplement_1): 3205.

https://doi.org/10.1182/blood-2019-126848

Published: 2019

Journal Articles

Mesenchymal COX2-Derived PGD2 Activates an ILC2-Treg Axis to Promote Proliferation of Normal and Malignant HSPCs

Limei Wu, MD, PhD, Qiqi Lin, Zhilin Ma, Fabliha Chowdhury, Md Habibul Mazumder, Wei Du, MD PhD

Blood (2019) 134 (Supplement_1): 1208.

https://doi.org/10.1182/blood-2019-124144

Published: 2019

Journal Articles

Gene Expression and Cytokine Analyses Identify Markers of Progression from CLL-like Monoclonal B-Cell Lymphocytosis to Chronic Lymphocytic Leukemia

Gonzalo Blanco, PhD, Anna Puiggros, PhD, Barbara Sherry, PhD, Lara Nonell, Eulalia Puigdecanet, Pui Yan Chiu, Yasmine Kieso, MSCR, Gerardo Ferrer, PhD, Magdalena Arnal, María Rodríguez-Rivera, Eva Gimeno, MD PhD, Eugenia Abella, Kanti R Rai, MD, Pau Abrisqueta, MD PhD, Xavier Calvo, MD PhD, Francesc Bosch, MD PhD, Ana Ferrer, MD PhD, Nicholas Chiorazzi, MD, Blanca Espinet, PhD

Blood (2019) 134 (Supplement_1): 3027.

https://doi.org/10.1182/blood-2019-122038

Published: 2019

Journal Articles

Efficient Elimination of Acute Myeloid Leukemia Cells through Inhibition of KDM4A in Combination with PARP Inhibition

Laura Monaghan, BSc, Matthew Edward Massett, MSc, BSc, Roderick P Bunschoten, BSc, Petrisor Alin Pirvan, MSc, BSc, Alex Hoose, Bsc, PhD, Taeju Park, BSc, Joana Bittencourt-Silvestre, BSc, MSc, Robert M J Liskamp, BSc, PhD, Heather G Jørgensen, Xu Huang, BSc, PhD

Blood (2019) 134 (Supplement_1): 3756.

https://doi.org/10.1182/blood-2019-125355

Published: 2019

Journal Articles

Efficacy Proof of Concept for Allogeneic CD123 Targeting CAR T-Cells Against Primary Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): Efficient Control of Tumor Progression in PDX Model and Potential Loss of CD123 Expression in Relapsed Disease

Blood (2019) 134 (Supplement_1): 2659.

https://doi.org/10.1182/blood-2019-126869

Published: 2019

Journal Articles

Mature Osteoblasts Promote Multiple Myeloma Survival through Cell-Cell Contact and Immune Modulation Mechanisms

Keertik Fulzele, PhD, Cristina Panaroni, PhD, Kenta Mukaihara, MD PhD, Tomoaki Mori, MD PhD, Shrikanta Chattopadhyay, MBBS, Noopur S. Raje, MD

Blood (2019) 134 (Supplement_1): 1802.

https://doi.org/10.1182/blood-2019-131213

Published: 2019

Journal Articles

Allogeneic Anti-Bcma CAR-T Cells Show Tumour Specific Killing Against Primary Multiple Myeloma Cells from Different Genomic Sub-Groups

Ana M Metelo, PhD, Ieuan Walker, BSc, MSc, MBBS, Agnieszka Jozwik, PhD, Charlotte Graham, MRCP, BSc, MBBS, Charlotte Attwood, BMedSci, MBBS, MRCP, FRCPath, Katy Sanchez, BSc, MSc, Alan Dunlop, BSc, MSc, Kirsty Cuthill, FRCPath,MBBS,MRCP,PhD, Carmel Rice, FRACP, FRCPA, MBBS, Matthew Streetly, MD, Trevor Bentley, BSc, Bijan Boldajipour, PhD, Cesar Sommer, PhD, Barbra Sasu, PhD, Reuben Benjamin, FRCPath, MRCP, MBBS, PhD

Blood (2019) 134 (Supplement_1): 1834.

https://doi.org/10.1182/blood-2019-124312

Published: 2019

Journal Articles

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

Blood (2019) 134 (19): 1670–1682.

https://doi.org/10.1182/blood.2019001950

Published: 2019

Journal Articles

Differential expression of Plg-R KT and its effects on migration of proinflammatory monocyte and macrophage subsets

Barbara Thaler, Nagyung Baik, Philipp J. Hohensinner, Johanna Baumgartner, Adelheid Panzenböck, Stefan Stojkovic, Svitlana Demyanets, Ihor Huk, Gersina Rega-Kaun, Christoph Kaun, Manfred Prager, Michael B. Fischer, Kurt Huber, Walter S. Speidl, Robert J. Parmer, Lindsey A. Miles, Johann Wojta

Blood (2019) 134 (6): 561–567.

https://doi.org/10.1182/blood.2018850420

Published: 2019

Journal Articles

Itacitinib, a JAK1 Selective Inhibitor Preserves Graft-Versus-Leukemia (GVL), Enhances Survival and Is Highly Efficacious in a MHC-Mismatched Mouse Model of Acute GvHD

Ashish Juvekar, Bruce Ruggeri, Sindy Condon, Andrew Borkowski, Reid Huber, PhD, Paul Smith

Blood (2018) 132 (Supplement 1): 4522.

https://doi.org/10.1182/blood-2018-99-112144

Published: 2018

Journal Articles

Ruxolitinib, a JAK1/JAK2 Selective Inhibitor Is Highly Efficacious in Corticosteroid Untreated and Refractory MHC-Mismatched Mouse Model of Acute GvHD

Ashish Juvekar, Bruce Ruggeri, Sindy Condon, Andrew Borkowski, Reid Huber, PhD, Paul Smith

Blood (2018) 132 (Supplement 1): 4523.

https://doi.org/10.1182/blood-2018-99-112223

Published: 2018

Journal Articles

Detailed Phenotypic, Molecular and Functional Profiling of Myeloid Derived Suppressor Cells (MDSCs) in the Tumor Immune Microenvironment (TIME) of Multiple Myeloma (MM)

Blood (2018) 132 (Supplement 1): 4436.

https://doi.org/10.1182/blood-2018-99-111102

Published: 2018

Journal Articles

IL-13 Expression Characterizes Effusions Associated with Primary Effusion Lymphoma but Not Other Disorders Caused By Kaposi Sarcoma Herpesvirus (KSHV)

Ramya Ramaswami, MBBS, MPH, Kathryn Lurain, MD MPH, Vickie Marshall, Nazzarena Labo, MD PhD, Anaida Widell, Matthew Lindsley, Mark N. Polizzotto, Denise Whitby, Thomas S. Uldrick, MD MS, Robert Yarchoan, MD

Blood (2018) 132 (Supplement 1): 4137.

https://doi.org/10.1182/blood-2018-99-117668

Published: 2018

Journal Articles

Composition of Classical Hodgkin Lymphoma Microenvironment Is Associated with Clinical Outcome

Olga Novosad, PhD MD, Tetiana Skrypets, MD, Nataliia Svergun, PhD, Oksana Skachkova, PhD, Oleksandr Gorbach, PhD, Nataliia Khranovska, PhD, Mykhailo Krotevych, PhD MD, Larisa Skoroda, MD, Maryna Koshubarova, MD, Dmitry Novikov, MD, Iryna Kriachok, Professor

Blood (2018) 132 (Supplement 1): 5313.

https://doi.org/10.1182/blood-2018-99-118987

Published: 2018

Journal Articles

A Critical Role of Host-Derived Semaphorin-4A for Regulating T Cell Immune Responses in Acute Graft Versus Host Disease

Hideaki Yoshimura, MD, Yukie Tsubokura, MD, Masaaki Hotta, MD, Atsushi Satake, MD PhD, Tomoki Ito, MD PhD, Atsushi Kumanogoh, MD PhD, Shosaku Nomura, MD PhD

Blood (2018) 132 (Supplement 1): 3322.

https://doi.org/10.1182/blood-2018-99-113853

Published: 2018

Journal Articles

Interferon Regulatory Factor 4 Is a Key Factor in Regulation of T helper Cell Polarization in Graft-Versus-Host Disease

Jochen T Frueh, MSc, BSc, Bushra Rais, PhD, Daniele Yumi Sunaga-Franze, Katja Stein, Sascha Sauer, PhD, Andreas G Chiocchetti, PhD, Michael Lohoff, PhD, Evelyn Ullrich, MD

Blood (2018) 132 (Supplement 1): 3313.

https://doi.org/10.1182/blood-2018-99-116151

Published: 2018

Journal Articles

Comparative Analysis of Proinflammatory Cytokine Levels in Peripheral Blood and Bone Marrow of Patients with Myeloproliferative Neoplasms

Pu Chen, Boting Wu, Xia Shao, Chanjuan Liu, Zhenglin Yu, Feng Li, Yunfeng Cheng, MD PhD

Blood (2018) 132 (Supplement 1): 4995.

https://doi.org/10.1182/blood-2018-99-115600

Published: 2018

NARROW

Disease Modeling of Severe Congenital Neutropenia Using CRISPR/Cas9 Gene Correction or Knockout of ELANE in Patients Derived Induced Pluripotent Stem Cells

A Phase 2 Study of the Dual SYK/JAK Inhibitor Cerdulatinib Demonstrates Good Tolerability and Clinical Response in Relapsed/Refractory Peripheral T-Cell Lymphoma and Cutaneous T-Cell Lymphoma

CLL B Cells Develop Resistance to Ibrutinib By Reinvigorating the IL-4R - IL-4 Axis Blocked By Bruton's Tyrosine Kinase Inhibitors Including Acalabrutinib and Zanubrutinib

Third Party Type 2 Innate Lymphoid Cells Treat and Prevent GI Tract Acute GvHD

Mesenchymal COX2-Derived PGD2 Activates an ILC2-Treg Axis to Promote Proliferation of Normal and Malignant HSPCs

Gene Expression and Cytokine Analyses Identify Markers of Progression from CLL-like Monoclonal B-Cell Lymphocytosis to Chronic Lymphocytic Leukemia

Efficient Elimination of Acute Myeloid Leukemia Cells through Inhibition of KDM4A in Combination with PARP Inhibition

Efficacy Proof of Concept for Allogeneic CD123 Targeting CAR T-Cells Against Primary Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): Efficient Control of Tumor Progression in PDX Model and Potential Loss of CD123 Expression in Relapsed Disease

Mature Osteoblasts Promote Multiple Myeloma Survival through Cell-Cell Contact and Immune Modulation Mechanisms

Allogeneic Anti-Bcma CAR-T Cells Show Tumour Specific Killing Against Primary Multiple Myeloma Cells from Different Genomic Sub-Groups

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

Differential expression of Plg-R KT and its effects on migration of proinflammatory monocyte and macrophage subsets

Itacitinib, a JAK1 Selective Inhibitor Preserves Graft-Versus-Leukemia (GVL), Enhances Survival and Is Highly Efficacious in a MHC-Mismatched Mouse Model of Acute GvHD

Ruxolitinib, a JAK1/JAK2 Selective Inhibitor Is Highly Efficacious in Corticosteroid Untreated and Refractory MHC-Mismatched Mouse Model of Acute GvHD

Detailed Phenotypic, Molecular and Functional Profiling of Myeloid Derived Suppressor Cells (MDSCs) in the Tumor Immune Microenvironment (TIME) of Multiple Myeloma (MM)

IL-13 Expression Characterizes Effusions Associated with Primary Effusion Lymphoma but Not Other Disorders Caused By Kaposi Sarcoma Herpesvirus (KSHV)

Composition of Classical Hodgkin Lymphoma Microenvironment Is Associated with Clinical Outcome

A Critical Role of Host-Derived Semaphorin-4A for Regulating T Cell Immune Responses in Acute Graft Versus Host Disease

Interferon Regulatory Factor 4 Is a Key Factor in Regulation of T helper Cell Polarization in Graft-Versus-Host Disease

Comparative Analysis of Proinflammatory Cytokine Levels in Peripheral Blood and Bone Marrow of Patients with Myeloproliferative Neoplasms

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American Society of Hematology

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American Society of Hematology

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