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Journal Articles

Bone Marrow Ribonucleotide Reductase mRNA Levels and Methylation Status As a Prognostic Factor in Patients with Myelodysplastic Syndrome Treated with 5-Azacytidine

Christina-Nefeli Kontandreopoulou, BSc, Panagiotis T Diamantopoulos, MD PhD, Argiris Symeonidis, MD PhD, Ioannis Kotsianidis, Vassiliki Pappa, MD, Athanasios Galanopoulos, MD PhD, Andreas Giannopoulos, BSc, MSc, Katerina Zoi, PhD, Maria Dimou, MD PhD, Elena E. Solomou, MD, Panayiotis Panayiotidis, MD, Georgios Kyriakakis, Nefeli Giannakopoulou, Georgios Dryllis, Sevastianos Chatzidavid, Nora-Athina Viniou, MD PhD

Blood (2019) 134 (Supplement_1): 1721.

https://doi.org/10.1182/blood-2019-126426

Published: 2019

Journal Articles

Identification of FASN-Dependent Onco-Metabolic Regulation of the Pentose Phosphate Pathway (PPP) and Nucleotide Metabolism in Non-Hodgkin Lymphoma (NHL)

Ravi Dashnamoorthy, PhD, Afshin Beheshti, PhD, Xiaoyang Su, PhD, Ying Chen, PhD, Maisarah Mokhtar, B.S, Gregory Dolnikowski, Frederick Lansigan, MD, William B Kinlaw, III, MD, Sandeep Dave, MD, Andrew M. Evens, DO, MSc

Blood (2019) 134 (Supplement_1): 1573.

https://doi.org/10.1182/blood-2019-126382

Published: 2019

Journal Articles

Modeling Human Paroxysmal Nocturnal Hemoglobinuria Via CRISPR/Cas9 HSPC Gene Editing in Non-Human Primate

Taehoon Shin, PhD, Eun Jung Baek, MD, Marcus A.F. Corat, PhD, Shirley Chen, BS, Robert E. Donahue, VMD, Kyung-Rok Yu, PhD, Cynthia E. Dunbar, MD

Blood (2018) 132 (Supplement 1): 1309.

https://doi.org/10.1182/blood-2018-99-111984

Published: 2018

Journal Articles

Loss of KDM6A/UTX Accelerate the Development of Multiple Myeloma

Daphne Dupere-Richer, PhD, Jianping Li, MD, Sayantan Maji, PhD, Crissandra Pipe, LATG, Sharon Norton, MS, Teresa Ezponda, PhD, Richard Lynn Bennett, PhD, Jonathan D. Licht, MD

Blood (2018) 132 (Supplement 1): 1004.

https://doi.org/10.1182/blood-2018-99-113835

Published: 2018

Journal Articles

Association between Gene Expression Levels of Candidate Cytarabine Pathway and Treatment Outcome Using Publically Available Data from Target Project

Abdelrahman Elsayed, BSc, MSc, Jatinder Lamba, PhD

Blood (2017) 130 (Supplement 1): 1400.

https://doi.org/10.1182/blood.V130.Suppl_1.1400.1400

Published: 2017

Journal Articles

p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma

Teru Hideshima, Francesca Cottini, Yoshihisa Nozawa, Hyuk-Soo Seo, Hiroto Ohguchi, Mehmet K. Samur, Diana Cirstea, Naoya Mimura, Yoshikazu Iwasawa, Paul G. Richardson, Nikhil C. Munshi, Dharminder Chauhan, Walter Massefski, Teruhiro Utsugi, Sirano Dhe-Paganon, Kenneth C. Anderson

Blood (2017) 129 (10): 1308–1319.

https://doi.org/10.1182/blood-2016-09-738500

Published: 2017

Includes: Supplemental data

Journal Articles

Targeting Ribonucleotide Reductase M1 and M2 in Multiple Myeloma

Morihiko Sagawa, MD PhD, Hiroto Ohguchi, MD PhD, Takeshi Harada, MD PhD, Mehmet K. Samur, PhD, Yu-Tzu Tai, PhD, Nikhil C Munshi, MD, Teru Hideshima, MD PhD, Kenneth C. Anderson, MD

Blood (2016) 128 (22): 360.

https://doi.org/10.1182/blood.V128.22.360.360

Published: 2016

Journal Articles

Phase I Study of the Combination of Azacitidine (AZA) with MEC (Mitoxantrone, Etoposide and Cytarabine) Salvage Chemotherapy in Relapsed/Refractory Acute Myeloid Leukemia (AML): Early Results

Rebecca B Klisovic, MD, Hongyan Wang, Alison Walker, MD, Katherine Walsh, MD, Sumithira Vasu, MBBS, Ramiro Garzon, MD, Steven M. Devine, MD, Jiang Wang, Celia Garr, RN, Adam Norris, John C. Byrd, MD, Michael R. Grever, MD, William Blum, MD, Kenneth K. Chan, Ph.D, Guido Marcucci, MD

Blood (2012) 120 (21): 3616.

https://doi.org/10.1182/blood.V120.21.3616.3616

Published: 2012

Journal Articles

Antileukemic effects of AMPK activators on BCR-ABL–expressing cells

Eliza Vakana, Jessica K. Altman, Heather Glaser, Nicholas J. Donato, Leonidas C. Platanias

Blood (2011) 118 (24): 6399–6402.

https://doi.org/10.1182/blood-2011-01-332783

Published: 2011

Includes: Supplemental data

Journal Articles

Activity of the Novel Ribonucleotide Reductase Inhibitor Didox on Human and Murine Models of Acute Leukemia,

Guerry J Cook, MSc, Howard L Elford, PhD, Timothy Pardee, MD, PhD

Blood (2011) 118 (21): 3637.

https://doi.org/10.1182/blood.V118.21.3637.3637

Published: 2011

Journal Articles

Inexpensive DNA Microarray Application for Screening of Beta-Globin Mutations in Low-Resource Settings.

Jesper Petersen, Martin Dufva, Henrik Birgens, MD

Blood (2009) 114 (22): 4067.

https://doi.org/10.1182/blood.V114.22.4067.4067

Published: 2009

Journal Articles

The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL

Francesco E. Boccalatte, Claudia Voena, Chiara Riganti, Amalia Bosia, Lucia D'Amico, Ludovica Riera, Mangeng Cheng, Bruce Ruggeri, Ole N. Jensen, Valerie L. Goss, Kimberly Lee, Julie Nardone, John Rush, Roberto D. Polakiewicz, Michael J. Comb, Roberto Chiarle, Giorgio Inghirami

Blood (2009) 113 (12): 2776–2790.

https://doi.org/10.1182/blood-2008-06-161018

Published: 2009

Includes: Supplemental data

Journal Articles

Therapeutic Nucleic Acids: A Potential Source of Resistance to Cancer, Antiviral and Immunosuppressive Therapy.

Raymund Buhmann, Ting Yang, Monica Schifferer, Martin Obermeier, Gundula Jaeger, Hans-Jochem Kolb

Blood (2008) 112 (11): 1614.

https://doi.org/10.1182/blood.V112.11.1614.1614

Published: 2008

Journal Articles

In Vitro Reconstitution of the NALP1 Inflammasome Reveals Requirements for Caspase Activation.

Benjamin Faustin, PhD, Lydia Lartigue, Ph.D., Jean-Marie Bruey, Ph.D., Frederic Luciano, Ph.D., Dorit Hanein, Ph.D., Isabelle Rouiller, Ph.D., John C. Reed, MD, Ph.D.

Blood (2006) 108 (11): 3658.

https://doi.org/10.1182/blood.V108.11.3658.3658

Published: 2006

Journal Articles

Hydroxyurea with Azacitidine or Decitabine in Combination Is Antagonistic on DNA Methylation Inhibition.

Si Ho Choi, MS, Hyang-Min Byun, Ph.D, Jennifer Kwan, BS, Allen S. Yang, MD, Ph.D

Blood (2006) 108 (11): 4303.

https://doi.org/10.1182/blood.V108.11.4303.4303

Published: 2006

Journal Articles

Species-Specific Differences in Human and Mouse Integrin Alpha-2 Expression.

Yann Cheli, MS, Thomas J. Kunicki, PhD

Blood (2005) 106 (11): 3561.

https://doi.org/10.1182/blood.V106.11.3561.3561

Published: 2005

Journal Articles

A Phase I Study of GTI-2040, an Antisense to Ribonucleotide Reductase (RNR) in Combination with High-Dose Cytarabine (HiDAC) in Relapsed or Refractory Acute Myeloid Leukemia (AML): Pharmacokinetics (PK), Pharmacodynamic (PD) and Clinical Results.

Rebecca B. Klisovic, W. Blum, X. Wei, S. Liu, C. Kefauver, L. Huynh, J. A. Zwiebel, J. C. Byrd, M. R. Grever, G. Marcucci

Blood (2005) 106 (11): 2790.

https://doi.org/10.1182/blood.V106.11.2790.2790

Published: 2005

Journal Articles

Phase I Study of Triapine® and Cytarabine (ara-C) in Patients with Relapsed or Refractory Acute Leukemias and High-Risk Myelodysplastic Syndrome (MDS).

Karen W.L. Yee, MD, Jorge Cortes, MD, Guillermo Garcia-Manero, MD, Srdan Verstovsek, MD, Alessandra Ferrajoli, MD, William G. Wierda, MD, Deborah Thomas, MD, Stefan Faderl, MD, Ivan King, PhD, Susan M. O’Brien, MD, Mario Sznol, MD, Francis J. Giles, MD

Blood (2005) 106 (11): 4925.

https://doi.org/10.1182/blood.V106.11.4925.4925

Published: 2005

Journal Articles

A Genomic and Proteomic Research for the Regulatory Networks of ATRA-Induced Differentiation of Acute Promyelocytic Leukemia Cells.

Qiu-Hua Huang, Qun-Ye Zhang, Shu-Hong Shen, Pei-Zheng Zheng, Jing Lu, Yi Jing, Ji Zhang, Kan-Kan Wang, Sai-Juan Chen, Zhu Chen

Blood (2004) 104 (11): 1174.

https://doi.org/10.1182/blood.V104.11.1174.1174

Published: 2004

Journal Articles

Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive anaplastic lymphoma kinase (ALK) tyrosine kinase activation by fusion to ATIC, an enzyme involved in purine nucleotide biosynthesis

Zhigui Ma, Jan Cools, Peter Marynen, Xiaoli Cui, Reiner Siebert, Stefan Gesk, Brigitte Schlegelberger, Benjamin Peeters, Christiane De Wolf-Peeters, Iwona Wlodarska, Stephan W. Morris

Blood (2000) 95 (6): 2144–2149.

https://doi.org/10.1182/blood.V95.6.2144

Published: 2000

NARROW

Bone Marrow Ribonucleotide Reductase mRNA Levels and Methylation Status As a Prognostic Factor in Patients with Myelodysplastic Syndrome Treated with 5-Azacytidine

Identification of FASN-Dependent Onco-Metabolic Regulation of the Pentose Phosphate Pathway (PPP) and Nucleotide Metabolism in Non-Hodgkin Lymphoma (NHL)

Modeling Human Paroxysmal Nocturnal Hemoglobinuria Via CRISPR/Cas9 HSPC Gene Editing in Non-Human Primate

Loss of KDM6A/UTX Accelerate the Development of Multiple Myeloma

Association between Gene Expression Levels of Candidate Cytarabine Pathway and Treatment Outcome Using Publically Available Data from Target Project

p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma

Targeting Ribonucleotide Reductase M1 and M2 in Multiple Myeloma

Phase I Study of the Combination of Azacitidine (AZA) with MEC (Mitoxantrone, Etoposide and Cytarabine) Salvage Chemotherapy in Relapsed/Refractory Acute Myeloid Leukemia (AML): Early Results

Antileukemic effects of AMPK activators on BCR-ABL–expressing cells

Activity of the Novel Ribonucleotide Reductase Inhibitor Didox on Human and Murine Models of Acute Leukemia,

Inexpensive DNA Microarray Application for Screening of Beta-Globin Mutations in Low-Resource Settings.

The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL

Therapeutic Nucleic Acids: A Potential Source of Resistance to Cancer, Antiviral and Immunosuppressive Therapy.

In Vitro Reconstitution of the NALP1 Inflammasome Reveals Requirements for Caspase Activation.

Hydroxyurea with Azacitidine or Decitabine in Combination Is Antagonistic on DNA Methylation Inhibition.

Species-Specific Differences in Human and Mouse Integrin Alpha-2 Expression.

A Phase I Study of GTI-2040, an Antisense to Ribonucleotide Reductase (RNR) in Combination with High-Dose Cytarabine (HiDAC) in Relapsed or Refractory Acute Myeloid Leukemia (AML): Pharmacokinetics (PK), Pharmacodynamic (PD) and Clinical Results.

Phase I Study of Triapine® and Cytarabine (ara-C) in Patients with Relapsed or Refractory Acute Leukemias and High-Risk Myelodysplastic Syndrome (MDS).

A Genomic and Proteomic Research for the Regulatory Networks of ATRA-Induced Differentiation of Acute Promyelocytic Leukemia Cells.

Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive anaplastic lymphoma kinase (ALK) tyrosine kinase activation by fusion to ATIC, an enzyme involved in purine nucleotide biosynthesis

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American Society of Hematology

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ASH Publications

American Society of Hematology

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