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Journal Articles

MYC Oncogene Abrogates Natural Killer (NK) Cell-Mediated Immune Surveillance of B- and T- Lymphoid Malignancies By Suppressing STAT1/2-Type I IFN Signaling

Srividya Swaminathan, PhD, Line Dam Heftdal, MD, Daniel Liefwalker, PhD, Renumathy Dhanasekaran, MD, Anja Deutzmann, PhD, Crista Horton, BS, Adriane Mosley, BS, Mariola Liebersbach, BS, Andrew Gentles, PhD, Holden T. Maecker, PhD, Dean Felsher, MD PhD

Blood (2019) 134 (Supplement_1): 730.

https://doi.org/10.1182/blood-2019-122607

Published: 2019

Journal Articles

STAT1 Transcriptional Response Predicts Molecular Responses of PB-Derived Clonogenic Cells from MPN Patients to Interferon Alpha

Milena Kalmer, MSc, Kristina Feldberg, Deniz Gezer, Susanne Isfort, Tim H Brümmendorf, MD, Nicolas Chatain, Steffen Koschmieder

Blood (2019) 134 (Supplement_1): 1679.

https://doi.org/10.1182/blood-2019-122676

Published: 2019

Journal Articles

Loss of Abelson Interactor-1 Is Linked to Inflammatory Hematopoiesis and Accelerated Aging of Hematopoietic System

Anna Dorota Chorzalska, PhD, John Morgan, PhD, Max Petersen, Diana O Treaba, MD, Adam J Olszewski, MD, John L. Reagan, MD, Patrycja Dubielecka, PhD

Blood (2018) 132 (Supplement 1): 1285.

https://doi.org/10.1182/blood-2018-99-118393

Published: 2018

Journal Articles

Dependency of Spliceosomal Mutant MDS on Innate Immune Signaling

Stanley C Lee, PhD, Khrystyna North, Chi-Chao Chen, Eunhee Kim, PhD, Sydney X. Lu, MD PhD, Michelle Ki, BSc, Ralph Garippa, PhD, Scott W Lowe, PhD, Robert K. Bradley, PhD, Omar I Abdel-Wahab, MD

Blood (2018) 132 (Supplement 1): 937.

https://doi.org/10.1182/blood-2018-99-111552

Published: 2018

Journal Articles

Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy

Blood (2018) 132 (7): 694–706.

https://doi.org/10.1182/blood-2017-10-810739

Published: 2018

Includes: Supplemental data

Journal Articles

NPM1-ALK Overexpression-Driven Toxicity in ALCL Is Partner Dependent and Mediated By STAT1 Antagonism of STAT3 Survival Signaling, Revealing a Novel Therapeutic Strategy

Soumya Sundara Rajan, M.Sc, Amit Dipak Amin, PhD, Lingxiao Li, PhD, Delphine C. M. Rolland, PharmD, PhD, Haiquan Li, PhD, Soham Puvvada, MD, Yves Lussier, MD, Megan S. Lim, MDPhD, Jonathan H. Schatz, MD

Blood (2017) 130 (Supplement 1): 2506.

https://doi.org/10.1182/blood.V130.Suppl_1.2506.2506

Published: 2017

Journal Articles

Higher Rates of Molecular Response to Peg-IFNa in JAK2V617F Vs. Calr Mutant MPN Patients Are Due to JAK1-Mediated STAT1 Activation and Autoregulation

Julia Czech, Sabrina Cordua, Barbora Weinbergerova, Lijuan Han, Claudia Schubert, Tim H. Brümmendorf, MD, Jiri Mayer, Prof, MD SCs, Zdenek Racil, MD, Blanka Kubesova, MSc, Trine Alma Knudsen, MD, Anders Sørensen, Morten Holmstrøm, Lasse Kjær, MSc, PhD, Vibe Skov, MSc, PhD, Thomas Stauffer Larsen, MD PhD, Hans Carl Hasselbalch, MD Professor, DMSc, Nicolas Chatain, Steffen Koschmieder

Blood (2017) 130 (Supplement 1): 4194.

https://doi.org/10.1182/blood.V130.Suppl_1.4194.4194

Published: 2017

Journal Articles

PD-L1 Is Regulated By Interferon Gamma and Interleukin 6 through STAT1 and STAT3 Signaling in Cutaneous T-Cell Lymphoma

Sung Hee Kil, PhD, Renee Estephan, BS, James Sanchez, PhD, Jasmine M. Zain, MD, Marshall E. Kadin, MD, James W. Young, MD, Steven T. Rosen, MD, Christiane Querfeld, MD PhD

Blood (2017) 130 (Supplement 1): 1458.

https://doi.org/10.1182/blood.V130.Suppl_1.1458.1458

Published: 2017

Journal Articles

RNA Sequencing Data-Driven Dissection of Human Plasma Cell Differentiation Reveals New Potential Transcription Regulators

Alboukadel Kassambara, PhD, Laurie Herviou, Michel Jourdan, Coraline Thibaut, Veronika Vikova, Olivier Elemento, PhD, Jerome Moreaux, PhD

Blood (2017) 130 (Supplement 1): 4382.

https://doi.org/10.1182/blood.V130.Suppl_1.4382.4382

Published: 2017

Journal Articles

Apoptotic Cells for the Prevention of Cytokine Release Syndrome (CRS) in CAR T-Cell Therapy

Dror Mevorach, MD, Veronique Amor, PhD, Yehudith Shabat

Blood (2016) 128 (22): 1626.

https://doi.org/10.1182/blood.V128.22.1626.1626

Published: 2016

Journal Articles

TLR Activation By MSC Derived Extracellular Vesicles Drives Myeloid Commitment

Young Me Yoon, BS, Natalya A Goloviznina, B.S., John Butler, BS, Santhosh Chakkaramakkil Verghese, PhD, Peter Kurre, MD

Blood (2016) 128 (22): 1470.

https://doi.org/10.1182/blood.V128.22.1470.1470

Published: 2016

Journal Articles

Interferon Gamma (IFNγ)/STAT1 Signaling in Host Antigen Present Cells Suppresses MHC Class II-Dependent Presentation of Self-Antigens and Development of Graft Versus Host Disease (GVHD)

Caisheng Lu, MD PhD, Huihui Ma, MD, PhD, Liangsong Song, MD, PhD, Shirong Li, PhD, Suzanne Lentzsch, MD PhD, Markus Y Mapara, MD PhD

Blood (2016) 128 (22): 2147.

https://doi.org/10.1182/blood.V128.22.2147.2147

Published: 2016

Journal Articles

Interferon-α signaling promotes embryonic HSC maturation

Peter Geon Kim, Matthew C. Canver, Catherine Rhee, Samantha J. Ross, June V. Harriss, Ho-Chou Tu, Stuart H. Orkin, Haley O. Tucker, George Q. Daley

Blood (2016) 128 (2): 204–216.

https://doi.org/10.1182/blood-2016-01-689281

Published: 2016

Includes: Supplemental data

Journal Articles

When the STATs are against you

Sophie Hambleton

Blood (2016) 127 (25): 3109–3110.

https://doi.org/10.1182/blood-2016-05-715029

Published: 2016

Journal Articles

Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype

Blood (2016) 127 (25): 3154–3164.

https://doi.org/10.1182/blood-2015-11-679902

Published: 2016

Includes: Supplemental data

Journal Articles

Stem Cell-like Megakaryocyte Progenitors As Driving Forces of IFN-Induced Emergency Megakaryopooesis

Blood (2015) 126 (23): 2391.

https://doi.org/10.1182/blood.V126.23.2391.2391

Published: 2015

Journal Articles

Benzene-Induced Leukemogenesis: Irreversible Inhibition of PTPN2 and Subsequent STAT1 Signaling Alteration By the Hematotoxic Metabolite Benzoquinone

Romain Duval, Linh-Chi Bui, PhD, Cécile Mathieu, Emile Petit, Jean-Marie Dupret, PhD, Jan Cools, PhD, Fabien Guidez, PhD, Christine Chomienne, MD PhD, Fernando Rodrigues-Lima, PhD

Blood (2015) 126 (23): 3671.

https://doi.org/10.1182/blood.V126.23.3671.3671

Published: 2015

Journal Articles

MSMD Patients with IFN-g-STAT1 Signaling Defect Present Enhanced Osteoclastogenesis and Bone Resorption

Shiho Nishimura, MD, Miyuki Tsumura, PhD, Osamu Hirata, MD PhD, Reiko Kagawa, MD, Yoko Mizoguchi, MD PhD, Satoshi Okada, MD PhD, Masao Kobayashi, MD PhD

Blood (2015) 126 (23): 3591.

https://doi.org/10.1182/blood.V126.23.3591.3591

Published: 2015

Journal Articles

Successful Therapy of a Patient with a Novel STAT1 Gain of Function Mutation and Life-Threatening Cytopenias with Janus Kinase Inhibitor Ruxolitinib

Katja G. Weinacht, MD PhD, Louis m Charbonnier, PhD, Ashley Plant, MD, Troy Torgerson, MD PhD, Sergei Rosenzweig, MD PhD, Thomas Fleisher, MD PhD, Luigi Daniele Notarangelo, MD

Blood (2015) 126 (23): 3434.

https://doi.org/10.1182/blood.V126.23.3434.3434

Published: 2015

Journal Articles

Ikaros-Dependent Downregulation of MYC with IMiDs in Myeloma (MM) Cells Is Mediated through the Depletion of the Acetylated Chromatin Reader BRD4 at Super-Enhancer Loci

Paola Neri, MD PhD, Ines Tagoug, PhD, Justin Simms, Ranjan Maity, PhD, Jacquelyn Babich, Victor Jimenez-Zepeda, MD, Peter Duggan, MD, Fariborz Kolvear, PhD, Jonathan J Keats, PhD, Leif Bergsagel, MD PhD, Nizar J Bahlis, MD

Blood (2015) 126 (23): 4175.

https://doi.org/10.1182/blood.V126.23.4175.4175

Published: 2015

NARROW

MYC Oncogene Abrogates Natural Killer (NK) Cell-Mediated Immune Surveillance of B- and T- Lymphoid Malignancies By Suppressing STAT1/2-Type I IFN Signaling

STAT1 Transcriptional Response Predicts Molecular Responses of PB-Derived Clonogenic Cells from MPN Patients to Interferon Alpha

Loss of Abelson Interactor-1 Is Linked to Inflammatory Hematopoiesis and Accelerated Aging of Hematopoietic System

Dependency of Spliceosomal Mutant MDS on Innate Immune Signaling

Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy

NPM1-ALK Overexpression-Driven Toxicity in ALCL Is Partner Dependent and Mediated By STAT1 Antagonism of STAT3 Survival Signaling, Revealing a Novel Therapeutic Strategy

Higher Rates of Molecular Response to Peg-IFNa in JAK2V617F Vs. Calr Mutant MPN Patients Are Due to JAK1-Mediated STAT1 Activation and Autoregulation

PD-L1 Is Regulated By Interferon Gamma and Interleukin 6 through STAT1 and STAT3 Signaling in Cutaneous T-Cell Lymphoma

RNA Sequencing Data-Driven Dissection of Human Plasma Cell Differentiation Reveals New Potential Transcription Regulators

Apoptotic Cells for the Prevention of Cytokine Release Syndrome (CRS) in CAR T-Cell Therapy

TLR Activation By MSC Derived Extracellular Vesicles Drives Myeloid Commitment

Interferon Gamma (IFNγ)/STAT1 Signaling in Host Antigen Present Cells Suppresses MHC Class II-Dependent Presentation of Self-Antigens and Development of Graft Versus Host Disease (GVHD)

Interferon-α signaling promotes embryonic HSC maturation

When the STATs are against you

Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype

Stem Cell-like Megakaryocyte Progenitors As Driving Forces of IFN-Induced Emergency Megakaryopooesis

Benzene-Induced Leukemogenesis: Irreversible Inhibition of PTPN2 and Subsequent STAT1 Signaling Alteration By the Hematotoxic Metabolite Benzoquinone

MSMD Patients with IFN-g-STAT1 Signaling Defect Present Enhanced Osteoclastogenesis and Bone Resorption

Successful Therapy of a Patient with a Novel STAT1 Gain of Function Mutation and Life-Threatening Cytopenias with Janus Kinase Inhibitor Ruxolitinib

Ikaros-Dependent Downregulation of MYC with IMiDs in Myeloma (MM) Cells Is Mediated through the Depletion of the Acetylated Chromatin Reader BRD4 at Super-Enhancer Loci

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American Society of Hematology

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American Society of Hematology

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