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Journal Articles

Platelets and extracellular vesicles and their cross talk with cancer

Sophia Lazar, Lawrence E. Goldfinger
Journal: Blood
Blood (2021) 137 (23): 3192–3200.
https://doi.org/10.1182/blood.2019004119
Published: 2021
Journal Articles

Myeloid cell–targeted miR-146a mimic inhibits NF-κB–driven inflammation and leukemia progression in vivo

Yu-Lin Su, Xiuli Wang, Mati Mann, Tomasz P. Adamus, Dongfang Wang, Dayson F. Moreira, Zhuoran Zhang, Ching Ouyang, Xin He, Bin Zhang, Piotr M. Swiderski, Stephen J. Forman, David Baltimore, Ling Li, Guido Marcucci, Mark P. Boldin, Marcin Kortylewski
Journal: Blood
Blood (2020) 135 (3): 167–180.
https://doi.org/10.1182/blood.2019002045
Published: 2020
Includes: Supplemental data
Journal Articles

Myeloid-Derived Suppressor Cells As Potential Contributors to Pregnancy-Associated Lymphoma Progression

Netanel A Horowitz, MD, Noam Bettman, PhD, Ali Abd El Wahed, Tamar Katz, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3979.
https://doi.org/10.1182/blood-2019-124292
Published: 2019
Journal Articles

DC Vaccination Induces Antigen Specific Immune Responses in AML Patients: A 1-Year Interim Assessment

Judith Eckl, PhD, Silke Raffegerst, PhD, Frauke Schnorfeil, PhD, Petra Prinz-Schulz, PhD, Christiane Fingerhut, Yngvar Floisand, MD PhD, Dag Josefsen, Iris Bigalke, MD, Kai Pinkernell, MDMBA, Gunnar Kvalheim, MD PhD, Dolores Schendel, Prof., Anna Tafuri, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3923.
https://doi.org/10.1182/blood-2019-129749
Published: 2019
Journal Articles

β 2 -m - a Trigger for NLRP3 Inflammasome Activation within Macrophages Promoting Multiple Myeloma Cell Proliferation

Daniel Hofbauer, Dimitrios Mougiakakos, MD, Maike Büttner-Herold, Frank Neumann, PhD, Jens Nolting, Savita Bisht, Robert Zeiser, MD, Shaima'A Hamarsheh, MSc,BSc, Stefano Ricagno, PhD, Mario Zaiss, Martin Eberhardt, Martin Boettcher, PhD, Katrin Bitterer, Andreas Mackensen, MD, Heiko Bruns, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2314.
https://doi.org/10.1182/blood-2019-123958
Published: 2019
Journal Articles

A Unique Crosstalk between Tumor Cells and Hematopoietic Stem Cells Reveals a Myeloid Differentiation Pattern Signature Contributing to Metastasis

Ksenia Magidey, PhD, Ksenya Kveler, PhD, Rachelly Normand, PhD, Tongwu Zhang, PhD, Michael Timaner, PhD, Ziv Raviv, PhD, Brian James, PhD, Roi Gazit, PhD, Ze'ev Ronai, PhD, Shai Shen-Orr, PhD, Yuval Shaked, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2465.
https://doi.org/10.1182/blood-2019-128126
Published: 2019
Journal Articles

The Clinical Significance of a Novel microRNA Signature in Multiple Myeloma

Pinelopi I Artemaki, BSc, Aristea-Maria Papanota, MD, Paraskevi Karousi, BSc, Christine Liacos, MSc, Christos K. Kontos, PhD, Dimitris Patseas, BSc, Maria-Alexandra Papadimitriou, BSc, Evangelos Eleutherakis-Papaiakovou, MD, Margaritis Avgeris, PhD, Nikolaos Kanellias, MD, Tina Bagratuni, PhD, Maria Roussou, MD, Ioanna Dialoupi, MD, Eftathios Kastritis, Maria Gavriatopoulou, MD, Meletios A. Dimopoulos, MD, Andreas Scorilas, PhD, Evangelos Terpos, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5529.
https://doi.org/10.1182/blood-2019-129218
Published: 2019
Journal Articles

Mitochondrial Genome-Derived Mc-COX2 with Novel Characteristics Predicts Prognosis of Patients with Chronic Lymphocytic Leukemia

Hui Jin, Jianyong Li, MD, Zijuan Wu, Handong Sun, Yi Xia, Jianxin Fu, MD PhD, Lei Fan, MD PhD, Wei Xu, MD PhD, Li Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4284.
https://doi.org/10.1182/blood-2019-124609
Published: 2019
Journal Articles

Mechanisms of Deregulation of Apoptosis in Myeloma

Simone Fulda, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-10.
https://doi.org/10.1182/blood-2019-121102
Published: 2019
Journal Articles

Host and Tumor Factor XII Drive Ovarian Cancer Maintenance and Progression

Evi X Stavrou, MD, Kara L. Bane, M.Sc., Peronne Joseph, M.Sc., Anil Belur Nagaraj, PhD, Analisa Difeo, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2384.
https://doi.org/10.1182/blood-2019-125862
Published: 2019
Journal Articles

Examining the Role of CD30 in an Anaplastic Large Cell Lymphoma Mouse Model

Teresa Poggio, Linda Graessel, Stefanie Kreutmair, Cornelius Miething, Dietmar Pfeifer, Geoffroy Andrieux, Melanie Boerries, Marie Follo, Suzanne Turner, Robert Zeiser, MD, Justus Duyster, MD, Anna Lena Illert
Journal: Blood
Blood (2019) 134 (Supplement_1): 2542.
https://doi.org/10.1182/blood-2019-125589
Published: 2019
Journal Articles

Diffuse Large B Cell Lymphoma (DLBCL)-Released NM23-H1 Promotes Monocyte Survival and Inflammatory Cytokine Release: A Mechanistic Link between the Dual Impacts of NM23-H1 Expression and Reduced Lymphocyte:Monocyte Ratio in DLBCL Prognosis

Sandro Trova, PhD, Maiss Al-Amere, PhD, Jayna J Mistry, BSc, Zuhal Eraslan, Bader Alhazmi, Joy Harris-Folb, Alessandro Di Maio, Mark T Drayson, MB ChB, PhD FRCPath, Christopher M Bunce, BSc, Stuart A Rushworth, PhD, Farhat Latif Khanim, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2803.
https://doi.org/10.1182/blood-2019-130889
Published: 2019
Journal Articles

Efficacy Proof of Concept for Allogeneic CD123 Targeting CAR T-Cells Against Primary Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): Efficient Control of Tumor Progression in PDX Model and Potential Loss of CD123 Expression in Relapsed Disease

Tianyu Cai, PhD, Kathryn L Black, PhD, Ammar S. Naqvi, PhD, Deanne Taylor, PhD, Ming Zhao, MD, Qi Yuan, Mayumi Sugita, MD, Roman Galetto, PhD, Agnès Gouble, PhD, Julianne N. P. Smith, PhD, Antonio Cavazos, Lina Han, PhD, Qi Zhang, PhD, Vinitha Mary Kuruvilla, MSc, Helen Ma, MS, Sergej Konoplev, Guilin Tang, MD, Jun Gu, MD PhD, Xiaoping Su, PhD, Sattva S Neelapu, MD, Andrew A. Lane, MD PhD, Hagop M. Kantarjian, MD, Monica L. Guzman, PhD, Naveen Pemmaraju, MD, Andrei Thomas-Tikhonenko, PhD, Marina Y Konopleva, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2659.
https://doi.org/10.1182/blood-2019-126869
Published: 2019
Journal Articles

The Broad Spectrum of TP53 Variants in CLL: NGS Analysis of 573 Pathogenic TP53 Variants

Gregory Lazarian, PharmD, Floriane Theves, Myriam Hormi, Virginie Eclache, Stéphanie Poulain, MD, Audrey Bidet, Cedric Pastoret, MD, Lauren Veronese, MD PhD, Eric Delabesse, MD PhD, Marie-Hélène Estienne, Nathalie Nadal, Frederic Davi, MD PhD, Florence Nguyen-Khac, MD PhD, Laurence Lode, Pierre Sujobert, MD PhD, Dina Naguib, MD, Sophie Raynaud, Stephane Giraudier, MD PhD, Olivier Kosmider, PharmD, PhD, Pascaline Etancelin, Pascale Cornillet-Lefebvre, Laurent Miguet, DPhil, Veronique Leblond, MD PhD, Remi Letestu, Thierry Soussi, Florence Cymbalista, MD PhD, Fanny Baran-Marszak, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3021.
https://doi.org/10.1182/blood-2019-130907
Published: 2019
Journal Articles

First-in-Human Study of ET019003, a Next Generation Anti-CD19 T-Cell Therapy, in Patients with Relapsed/Refractory Diffuse Large B Cell Lymphoma (r/r DLBCL)

Pengcheng He, Hong Liu, Haibo Liu, Mina Luo, Hui Feng, Qijing Li, Qi Chang, Bingyi Shi, Cheng Liu
Journal: Blood
Blood (2019) 134 (Supplement_1): 2870.
https://doi.org/10.1182/blood-2019-131414
Published: 2019
Journal Articles

Clinical Response in Relapsed/Refractory (R/R) B-NHL Treated with the CD19-Directed CAR T-Cell Product JWCAR029

Zhitao Ying, MD PhD, Pengpeng Xu, MD, Li Wang, MD PhD, Shu Cheng, MD PhD, Wen Wu, MD PhD, Wen Wang, MD PhD, Ming Hao, PhD, Su Yang, Harry Lam, PhD, James Li, Hongxia Zheng, MD PhD, Weili Zhao, MD PhD, Yuqin Song, MD PhD, Jun Zhu, BS
Journal: Blood
Blood (2019) 134 (Supplement_1): 2876.
https://doi.org/10.1182/blood-2019-127751
Published: 2019
Journal Articles

Inflammatory Cytokine Responsive Enzymatic Mutagenesis Fuels Myeloproliferative Neoplasm Pre-Leukemia Stem Cell Evolution

Catriona Jamieson, MD PhD, Qingfei Jiang, PhD, Frida Holm, PhD, Jane Isquith, MS, Adam Mark, Cayla Mason, BS, Wenxue Ma, MD PhD, Raymond H Diep, Jessica Pham, B.S., Eduardo Reynoso Moreno, PhD, Chanond A Nasamran, Xu Guorong, Amanda Birmingham, Leslie A Crews, PhD, Ludmil Alexandrov, Gabriel Pineda, PhD, Thomas Whisenant, Kathleen M Fisch
Journal: Blood
Blood (2019) 134 (Supplement_1): 3780.
https://doi.org/10.1182/blood-2019-131510
Published: 2019
Journal Articles

Targeting eIF4A Using MZ-735 Potently Induces Cell Death in Lymphoma Cells and Rapidly Represses mRNA Translation at the Global Level and in C-MYC and Other Oncogenes

Ipsita Pal, PhD, Yu Ri Kim, MD, Sohani Das Sharma, PhD, Prabhjot S. Mundi, MD, Andre M. Grilo, PhD, Luke E Berchowitz, PhD, Mingzhao Zhu, PhD, Hull G. Kenneth, PhD, Daniel Romo, PhD, Owen O'Connor, MD PhD, Marko Jovanovic, PhD, Changchun Deng, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4067.
https://doi.org/10.1182/blood-2019-131816
Published: 2019
Journal Articles

First-in-Human Study of the EZH1/2 Dual Inhibitor Valemetostat in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) - Updated Results Focusing on Adult T-Cell Leukemia-Lymphoma (ATL)

Satoko Morishima, MD PhD, Kenji Ishitsuka, MD PhD, Koji Izutsu, MD PhD, Shigeru Kusumoto, MD PhD, Junya Makiyama, MD PhD, Atae Utsunomiya, MD, Kisato Nosaka, MD PhD, Takashi Ishida, MD PhD, Yoshitaka Imaizumi, MD PhD, Nobuhiko Yamauchi, MD, Kazushi Araki, DVM, PhD, Nobuaki Adachi, PhD, Tomonari Yamashita, Ryo Atsumi, PhD, Kunihiro Tsukasaki, MD PhD, Kensei Tobinai, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4025.
https://doi.org/10.1182/blood-2019-125507
Published: 2019
Journal Articles

Characterization of Monoclonal Gammopathy of Undetermined Significance Progression to Multiple Myeloma through Meta-Analysis of GEO Data

Jihad Aljabban, MMSc, BA, David Chen, BS, Francesca Cottini, MD, Saad Syed, BS, Nabeal Aljabban, BS, Sharjeel Syed, BS, Tiffany Hughes, PhD, David Feldman, BS, Dexter Hadley, MD PhD, Don M. Benson, Jr., MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4395.
https://doi.org/10.1182/blood-2019-129699
Published: 2019