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Adrián Alegre
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Journal Articles

Covalent Menin Inhibitor Bmf-219 in Patients with Relapsed or Refractory (R/R) Acute Leukemia (AL): Preliminary Phase 1 Data from the Covalent-101 Study

Jeffrey Lancet, Farhad Ravandi, Pau Montesinos, Jacqueline C. Barrientos, Talha Badar, Adrián Alegre, Asad Bashey, Juan Miguel Bergua Burgues, Lorenzo Brunetti, Emily K Curran, David C. Christian de Leeuw, Enrico Derenzini, Geert A. Huls, Jeroen J.W.M. Janssen, Deepa Jeyakumar, Mojca Jongen-Lavrencic, Ashwin Kishtagari, Maria-Victoria Mateos, Daniel Morillo, Alessandro Rambaldi, Aaron S. Rosenberg, Gary J. Schiller, Uzma Ahmed, Alexandru Cacovean, Stephan W. Morris, Courtney Follit, Brian Munneke, Ganesh Waghmare, Clarissa Mandap, Mona Vimal, Thomas Butler, Hetty E. Carraway
Journal: Blood
Blood (2023) 142 (Supplement 1): 2916.
https://doi.org/10.1182/blood-2023-173149
Published: 2023
Journal Articles

Isolated and Dynamic Peripheral Blood Residual Disease Status Characterized By Mass Spectrometry Predicts Outcome in Patients with High Risk Smoldering Multiple Myeloma Treated in the GEM-CESAR Trial

Noemi Puig, Cristina Agullo, Teresa Contreras, Bruno Paiva, Maria Teresa Cedena Romero, José Juan Pérez, Irene Aires, Joaquin Martinez-Lopez, Paula Rodriguez Otero, Veronica Gonzalez-Calle, Marta Sonia Gonzalez Perez, Norma C. Gutierrez, Albert Oriol Rocafiguera, Rafael Ríos, Laura Rosiñol, Miguel Angel Alvarez Rivas, Maria Jose Calasanz, Bargay Joan, Ramon Garcia-Sanz, Ana Pilar Gonzalez, Adrián Alegre, Fernando Escalante, Rafael Martínez, Javier De La Rubia, Ana Isabel Teruel, Felipe De Arriba, Luis Palomera, Sergio Castro, Miguel Teodoro Hernández Garcia, Javier López, Aránzazu García Mateo, Enrique M Ocio, Joan Bladé, Juan Jose Lahuerta Palacios, Jesús San Miguel, Maria Victoria Mateos
Journal: Blood
Blood (2023) 142 (Supplement 1): 645.
https://doi.org/10.1182/blood-2023-182964
Published: 2023
Journal Articles

COVID-19 Severity and Survival over Time in Vaccinated Patients with Hematologic Malignancies

Joaquin Martinez Lopez, Javier De La Cruz, Rodrigo Gil-Manso, Celina Benavente Cuesta, Lauren Benito, jose Angel Hernandez, Maria Regina Herraez, Pilar Herrera Puente, Mi Kwon, Keina Quiroz, Andres Arroyo, Adrian Alegre, María Pilar Llamas Sillero, Javier López Jiménez, Pedro Sanchez-Godoy, Rafael F. Duarte, Jose L. Diez Martin, Víctor Jiménez-Yuste, Julio Garcia-Suarez
Journal: Blood
Blood (2022) 140 (Supplement 1): 7924–7925.
https://doi.org/10.1182/blood-2022-169545
Published: 2022
Journal Articles

Immune Biomarkers of Survival and Severe Infection in Newly Diagnosed Multiple Myeloma (NDMM) Patients (pts) Treated with the Backbone Regimen Lenalidomide and Dexamethasone (Rd)

Catarina Maia, Noemi Puig, Cristina Pérez Ruiz, Maria Teresa Cedena Romero, Camila Guerrero, Marta Larrayoz, Cirino Botta, Norma C. Gutierrez, María José Calasanz, Maria Luisa Martin-Ramos, Miguel Hernández, Laura Rosinol Dachs, Esther González Garcia, Felipe De Arriba, Albert Oriol, Veronica Gonzalez-Calle, Fernando Escalante, Javier de la Rubia, Mercedes Gironella Mesa, Rafael Rios, Ricarda Belen Garcia Sanchez, Jose Maria Arguiñano PEREZ, Adrian Alegre, Jesus Martin, María del Carmen Couto Caro, Maria Casanova, Mario Arnao Herraiz, Ernesto Pérez, Sebastián Garzón López, Marta Sonia Gonzalez Perez, Guillermo Martín-Nuñez, Adriana Rossi, Morton Coleman, Cristina Encinas, Ana M. Vale, Ana Isabel Teruel, María Cortés Rodríguez, Jose A. Martinez-Climent, Juan-José Lahuerta, Joan Bladé Creixenti, Ruben Niesvizky, Jesús San-Miguel, Maria-Victoria Mateos, Bruno Paiva
Journal: Blood
Blood (2022) 140 (Supplement 1): 4200–4203.
https://doi.org/10.1182/blood-2022-163058
Published: 2022
Journal Articles

Elranatamab in Combination with Daratumumab for Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM): Results from the Phase 3 Magnetismm-5 Study Safety Lead-in Cohort

Sebastian Grosicki, Ulf-Henrik Mellqvist, Łukasz Pruchniewski, Jacob Crafoord, Suzanne Trudel, Chang-Ki Min, Darrell White, Adrian Alegre, Markus Hansson, Takashi Ikeda, Kazutaka Sunami, Eric Leip, Arthur Kudla, Gregory Finn, Youngil Koh
Journal: Blood
Blood (2022) 140 (Supplement 1): 4407–4408.
https://doi.org/10.1182/blood-2022-162738
Published: 2022
Journal Articles

Curative Strategy (GEM-CESAR) for High-Risk Smoldering Myeloma (SMM): Post-Hoc Analysis of Sustained Undetectable Measurable Residual Disease (MRD)

Maria-Victoria Mateos, Joaquín Martínez-López, Paula Rodríguez-Otero, Jesús San-Miguel, Veronica Gonzalez-Calle, Marta Sonia Gonzalez, Albert Oriol, Norma C. Gutierrez, Rafael Rios, Laura Rosinol Dachs, Miguel Angel Alvarez, Joan Bargay, Ana Pilar Gonzalez, Fernando Escalante, Adrian Alegre, Belén Iñigo, Javier de la Rubia, Ana Isabel Teruel, Felipe De Arriba, Luis Palomera, Miguel-Teodoro Hernández, Javier Lopez Jimenez, Marta Reinoso Segura, Aránzazu García Mateo, Enrique M. Ocio, Joan Bladé, Juan-José Lahuerta, María Teresa Cedena, Noemi Puig, Bruno Paiva
Journal: Blood
Blood (2022) 140 (Supplement 1): 292–294.
https://doi.org/10.1182/blood-2022-159606
Published: 2022
Journal Articles

Impact of the COVID-19 Pandemic on the Incidence Registry of Hematological Neoplasms in the Region of Madrid (Spain). Preliminary Report of 2014-2021

Adrian Alegre, Luis Juarez-Salcedo, Víctor Jiménez-Yuste, Julio Garcia-Suarez, José Luis Díez-Martín, Joaquín Martínez-López, Beatriz Aguado, José Ángel Hernández-Rivas, Lauren Benito, Pilar Martinez-Barranco, Javier López Jiménez, Pedro Sanchez-Godoy, Fj Peñalver, Alberto Velasco, Adriana Pascual, Celina Benavente Cuesta, María Pilar Llamas Sillero, Juan Francisco DEL Campo, Elena Ruiz, Regina Herraez, Javier Ortiz, Carolina Miranda, Gregorio Garrido
Journal: Blood
Blood (2022) 140 (Supplement 1): 10965–10966.
https://doi.org/10.1182/blood-2022-167155
Published: 2022
Journal Articles

Belantamab Mafodotin in Patients with Relapsed/Refractory Multiple Myeloma Included in the Compassionate Use or the Expanded Access Program. Experience with a Spanish Cohort

Javier De La Rubia, Rafael Alonso, Maria Esther Clavero Sanchez, Elham Askari, Alfonso García de Coca, Ana Maldonado, Margarita Fernandez De La Mata, Fernando Escalante, Ana Garcia-Feria, Rafael Rios, Venancio Conesa, Maria Aranzazu Bermudez, Beatriz Merchan, Alberto Velasco, María Jesús Blanchard, Antonia Sampol, Eukene Gainza González, Pedro M Hernandez, Veronica Gonzalez-Calle, Adrian Alegre
Journal: Blood
Blood (2022) 140 (Supplement 1): 4315–4317.
https://doi.org/10.1182/blood-2022-158538
Published: 2022
Journal Articles

Acute and Post-Acute COVID-19 Severity and Mortality in Patients with Hematologic Malignancies: A Population-Based Registry Study

Joaquin Martinez-Lopez, Javier De La Cruz, Rodrigo Gil-Manso, Angel Cedillo, Adrian Alegre, Maria Pilar Llamas Sillero, Rafael F. Duarte, Víctor Jiménez-Yuste, jose Angel Hernandez, Mi Kwon, Pedro Sanchez Godoy, Pilar Martinez-Barranco, Blanca Colás Lahuerta, Pilar Herrera Puente, Lauren Benito, Alberto Velasco, Arturo Matilla, Concha Alaez, Rafael Martos, Carmen Martínez-Chamorro, Keina Quiroz, Juan F del Campo, Adolfo De La Fuente, Maria Regina Herraez, Adriana Pascual, Elvira Gomez, Jaime Perez De Oteyza, Elena Ruiz, Jose Luis Diez Martin, Julio Garcia-Suarez
Journal: Blood
Blood (2021) 138 (Supplement 1): 186.
https://doi.org/10.1182/blood-2021-152539
Published: 2021
Journal Articles

Severity of Covid-19 Clinical Outcomes and Mortality in Multiple Myeloma Patients over Year 1 of the Pandemic

Joaquín Martínez-López, Maria-Victoria Mateos, Nieves López-Muñoz, Maria Alicia Senin Magan, Maria Dunia De Miguel, Ana López de la Guía, Anna Sureda, Cristina Encinas, Diego Conde Royo, Laura Rosinol, Lucía García Tomás, Jose Angel Hernandez-Rivas, Javier Alberto Rojas, Adrian Alegre, María Jesús Blanchard, Fernando Escalante Barrigón, Esther González Garcia, Belén Iñigo, Pilar Bravo Barahona, F. Javier Penalver, Javier De La Rubia, Noemi Fernandez-Escalada, Jose Maria Alonso Alonso, Joan Bladé, Juan Jose Lahuerta, Javier De La Cruz, Jesús F. San-Miguel
Journal: Blood
Blood (2021) 138 (Supplement 1): 2719.
https://doi.org/10.1182/blood-2021-149192
Published: 2021
Journal Articles

Curative Strategy (GEM-CESAR) for High-Risk Smoldering Myeloma (SMM): Carfilzomib, Lenalidomide and Dexamethasone (KRd) As Induction Followed By HDT-ASCT, Consolidation with Krd and Maintenance with Rd

Maria-Victoria Mateos, Joaquin Martinez Lopez, Paula Rodríguez-Otero, Veronica Gonzalez-Calle, Marta Sonia Gonzalez, Albert Oriol, Norma C. Gutierrez, Rafael Rios, Laura Rosinol, Miguel Angel Alvarez, Joan Bargay, Ana Pilar Gonzalez, Adrian Alegre, Fernando Escalante, Belén Iñigo, Javier de la Rubia, Ana Isabel Teruel, Felipe De Arriba, Luis Palomera, Miguel-Teodoro Hernández, Javier Lopez Jimenez, Aránzazu García Mateo, Marta Reinoso Segura, Enrique Ocio, Bruno Paiva, Noemi Puig, María Teresa Cedena, Joan Bladé, Juan Jose Lahuerta, Jesús F. San-Miguel
Journal: Blood
Blood (2021) 138 (Supplement 1): 1829.
https://doi.org/10.1182/blood-2021-148423
Published: 2021
Journal Articles

Compassionate Use of Belantamab Mafodotin for Treatment of Patients with Relapsed/Refractory Multiple Myeloma Heavily Treated. Spanish Experience

Adrian Alegre, Gonzalo Benzo Callejo, Rafael Alonso Fernández, Joaquin Martínez-López, Ana Jimenez-Ubieto, Clara Cuellar, Elham Askari, Elena Prieto, Concha Alaez, Beatriz Aguado, Alberto Velasco, Isabel Krsnik, Laura Llorente, Cristina Muñoz-Linares, Ana Morales, Eugenio Gimenez Mesa, Rebeca Iglesias, Carmen Martínez-Chamorro, Arancha Alonso, Carmen Jiménez-Montes, María Jesús Blanchard
Journal: Blood
Blood (2021) 138 (Supplement 1): 3775.
https://doi.org/10.1182/blood-2021-151267
Published: 2021
Journal Articles

HORIZON (OP-106): Melflufen Plus Dexamethasone (dex) in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM) Exposed to Prior Alkylator Therapy-Subgroup Analysis

Paula Rodríguez-Otero, MD PhD, María-Victoria Mateos, MD PhD, Albert Oriol, Alessandra Larocca, Joan Blade Creixenti, Michele Cavo, Xavier Leleu, MD, Maxim Norkin, MD PhD, Omar Nadeem, MD, John W. Hiemenz, MD, Hani Hassoun, MD, Cyrille Touzeau, Adrián Alegre Amor, MD PhD, Agne Paner, MD, Christopher Maisel, MD, Amitabha Mazumder, MD, Anastasios Raptis, MD, Noemí Puig, MD PhD, Marcus Thuresson, PhD, Johan Harmenberg, MD PhD, Olof Harlin, VMD, PhD, Paul G. Richardson, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 22–23.
https://doi.org/10.1182/blood-2020-136466
Published: 2020
Journal Articles

HORIZON (OP-106): Melflufen Plus Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma-Age Subgroup Analysis of Elderly Patients

Alessandra Larocca, Paul G. Richardson, MD, Albert Oriol, Joan Blade Creixenti, Michele Cavo, Paula Rodríguez-Otero, MD PhD, Xavier Leleu, MD, Maxim Norkin, MD PhD, Omar Nadeem, MD, John W. Hiemenz, MD, Hani Hassoun, MD, Cyrille Touzeau, Adrián Alegre Amor, MD PhD, Agne Paner, MD, Christopher Maisel, MD, Amitabha Mazumder, MD, Anastasios Raptis, MD, Noemí Puig, MD PhD, Marcus Thuresson, PhD, Johan Harmenberg, MD PhD, Bengt Gustavsson, Dr MDSci, MSc Pharm, María-Victoria Mateos, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44–46.
https://doi.org/10.1182/blood-2020-136856
Published: 2020
Journal Articles

HORIZON (OP-106): Melflufen Plus Dexamethasone (dex) in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM)-Analysis of Adverse Events Related to Hospitalizations

Omar Nadeem, MD, Paul G. Richardson, MD, María-Victoria Mateos, MD PhD, Albert Oriol, Alessandra Larocca, Joan Blade Creixenti, Paula Rodríguez-Otero, MD, Xavier Leleu, MD, Maxim Norkin, MD PhD, John W. Hiemenz, MD, Hani Hassoun, MD, Cyrille Touzeau, Adrián Alegre Amor, MD PhD, Agne Paner, MD, Christopher Maisel, MD, Amitabha Mazumder, MD, Anastasios Raptis, MD, Noemí Puig, MD PhD, Anna Sandberg, MmSc, Ivonne Pelaez, MD, Christian Jaques, MD, Marie Orre, PhD, Michele Cavo
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–22.
https://doi.org/10.1182/blood-2020-136000
Published: 2020
Journal Articles

HORIZON (OP-106) Versus MAMMOTH: An Indirect Comparison of Efficacy Outcomes for Patients with Relapsed/Refractory Multiple Myeloma Refractory (RRMM) to Anti-CD38 Monoclonal Antibody Therapy Treated with Melflufen Plus Dexamethasone Versus Conventional Agents

Joan Blade Creixenti, María-Victoria Mateos, MD PhD, Albert Oriol, Alessandra Larocca, Michele Cavo, Paula Rodríguez-Otero, MD PhD, Xavier Leleu, MD, Maxim Norkin, MD PhD, Omar Nadeem, MD, John W. Hiemenz, MD, Hani Hassoun, MD, Cyrille Touzeau, Adrián Alegre Amor, MD PhD, Agne Paner, MD, Christopher Maisel, MD, Amitabha Mazumder, MD, Anastasios Raptis, MD, Noemí Puig, MD PhD, Stojan Zavisic, BSc, Marcus Thuresson, PhD, Johan Harmenberg, MD PhD, Paul G. Richardson, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–4.
https://doi.org/10.1182/blood-2020-137164
Published: 2020
Journal Articles

HORIZON (OP-106): Melflufen Plus Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma with High-Risk Cytogenetics-Subgroup Analysis

María-Victoria Mateos, MD PhD, Albert Oriol, Alessandra Larocca, Joan Blade Creixenti, Michele Cavo, Paula Rodríguez-Otero, MD, Xavier Leleu, MD, Maxim Norkin, MD PhD, Omar Nadeem, MD, John W. Hiemenz, MD, Hani Hassoun, MD, Cyrille Touzeau, Adrián Alegre Amor, MD PhD, Agne Paner, MD, Christopher Maisel, MD, Amitabha Mazumder, MD, Anastasios Raptis, MD, Noemí Puig, MD PhD, Johan Harmenberg, MD PhD, Bengt Gustavsson, Dr MDSci, MSc Pharm, Marcus Thuresson, PhD, Paul G. Richardson, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 41–43.
https://doi.org/10.1182/blood-2020-136002
Published: 2020
Journal Articles

HORIZON (OP-106): Melflufen Plus Dexamethasone (dex) in 55 Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM) with Extramedullary Disease (EMD)-Subgroup Analysis

Paul G. Richardson, MD, María-Victoria Mateos, MD PhD, Albert Oriol, Alessandra Larocca, Michele Cavo, Paula Rodríguez-Otero, MD PhD, Xavier Leleu, MD, Maxim Norkin, MD PhD, Omar Nadeem, MD, John W. Hiemenz, MD, Hani Hassoun, MD, Cyrille Touzeau, Adrián Alegre Amor, MD PhD, Agne Paner, MD, Christopher Maisel, MD, Amitabha Mazumder, MD, Anastasios Raptis, MD, Noemí Puig, MD PhD, Elena Zamagni, Marcus Thuresson, PhD, Johan Harmenberg, MD PhD, Olof Harlin, VMD, PhD, Joan Blade Creixenti
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–17.
https://doi.org/10.1182/blood-2020-137118
Published: 2020
Journal Articles

HORIZON (OP-106): Melflufen Plus Dexamethasone (dex) in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM) - Health-Related Quality of Life (HRQoL) Analysis

Albert Oriol, Paul G. Richardson, MD, María-Victoria Mateos, MD PhD, Alessandra Larocca, Joan Blade Creixenti, Michele Cavo, Paula Rodríguez-Otero, MD, Maxim Norkin, MD PhD, Omar Nadeem, MD, John W. Hiemenz, MD, Hani Hassoun, MD, Cyrille Touzeau, Adrián Alegre Amor, MD PhD, Agne Paner, MD, Christopher Maisel, MD, Amitabha Mazumder, MD, Anastasios Raptis, MD, Noemí Puig, MD PhD, Peter Strang, MD, Anna Sandberg, MmSc, Christian Jaques, MD, Marcus Thuresson, PhD, Marie Orre, PhD, Xavier Leleu, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 27–29.
https://doi.org/10.1182/blood-2020-135995
Published: 2020
Journal Articles

Safety and Preliminary Efficacy Results from a Phase Ib/II Study of Cobimetinib As a Single Agent and in Combination with Venetoclax with or without Atezolizumab in Patients with Relapsed/Refractory Multiple Myeloma

Fredrik Schjesvold, Vincent Ribrag, MD, Paula Rodriguez-Otero, MD PhD, Pawel J. Robak, MDPhD, Markus Hansson, MD, Roman Hajek, Adrián Alegre Amor, MD PhD, Joaquin Martinez-López, Maika Onishi, Jorge D. Gallo, Aparna Raval, Sameer Deshpande, Vikram Malhi, Wan-Jen Hong, MD, Marc S. Raab, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 45–46.
https://doi.org/10.1182/blood-2020-135845
Published: 2020