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Journal Articles

Blood Flow Directs Yap/Taz-Mediated Transcriptional Regulation of Self-Renewal Programs to Control Developmental HSPC Expansion By Mechanical Stimulation of Piezo1

Blood (2023) 142 (Supplement 1): 1309.

https://doi.org/10.1182/blood-2023-190416

Published: 2023

Journal Articles

Somatic Mutational Landscape of Hereditary Hematopoietic Malignancies Associated with Germline Variants in RUNX1 , GATA2 and DDX41

Anna L. Brown, Claire Homan, Michael W. Drazer, Kai Yu, David Lawrence, Jinghua Feng, Luis Arriola-Martinez, Matthew Pozsgai, Kelsey McNeely, Thuong Ha, Parvathy Venugopal, Peer Arts, Sarah King-Smith, Jesse JC Cheah, Mark Armstrong, Csaba Bödör, Paul Wang, Alan B. Cantor, Mario Cazzola, Erin Degelman, Courtney D. DiNardo, Nicolas Duployez, Remi Favier, Stefan Fröhling, Ana Rio-Machin, Jeffery M. Klco, Alwin Krämer, Mineo Kurokawa, Joanne Lee, Luca Malcovati, Neil V Morgan, Georges Natsoulis, Carolyn Owen, Keyur P. Patel, Claude Preudhomme, Hana Raslova, Hugh Young Rienhoff, Jr., Tim Ripperger, Rachael Schulte, Kiran Tawana, Elvira Deolinda Rodrigues Pereira Velloso, Benedict Yan, Raman Sood, Amy Hsu, Steven M. Holland, Kerry Phillips, Nicola Poplawski, Milena Babic, Erika M Kwon Kim, Andrew H. Wei, Cecily Forsyth, Helen Mar Fan, Ian D Lewis, Julian Cooney, Rachel Susman, Lucy C Fox, Piers Blombery, Deepak Singhal, Devendra Hiwase, Andreas W Schreiber, Christopher N Hahn, Hamish S Scott, Paul P. Liu, Lucy A. Godley

Blood (2022) 140 (Supplement 1): 4030–4033.

https://doi.org/10.1182/blood-2022-167600

Published: 2022

Journal Articles

Germline GATA1s-generating mutations predispose to leukemia with acquired trisomy 21 and Down syndrome-like phenotype

Henrik Hasle, Ronald M. Kline, Eigil Kjeldsen, Nik F. Nik-Abdul-Rashid, Deepa Bhojwani, Jeffrey M. Verboon, Stephanie P. DiTroia, Katherine R. Chao, Klas Raaschou-Jensen, Josefine Palle, C. Michel Zwaan, Charlotte Guldborg Nyvold, Vijay G. Sankaran, Alan B. Cantor

Blood (2022) 139 (21): 3159–3165.

https://doi.org/10.1182/blood.2021011463

Published: 2022

Includes: Supplemental data

Journal Articles

Profound intravascular hemolysis due to clostridial sepsis in an infant with necrotizing enterocolitis

Rahela Aziz-Bose, Alan B. Cantor

Blood (2021) 137 (16): 2273.

https://doi.org/10.1182/blood.2021011159

Published: 2021

Journal Articles

Cell Cycle Regulates Phosphorylation of RUNX1 to Modulate Megakaryocyte-Erythroid Progenitor Fate Specification

Yi-Chien Lu, PhD, Vanessa M Scanlon, PhD, Juliana Xavier-Ferrucio, PhD, Lin Wang, MS, Alan Friedman, Alan B. Cantor, MD PhD, Diane S. Krause, MD PhD

Blood (2020) 136 (Supplement 1): 15.

https://doi.org/10.1182/blood-2020-141156

Published: 2020

Journal Articles

Development of a Data Portal for Aggregation and Analysis of Genomics Data in Familial Platelet Disorder with Predisposition to Myeloid Malignancy - the RUNX1.DB

Anna L. Brown, PhD BSc, Mark Armstrong, MSc, David Lawrence, Paul Wang, Peer Arts, PhD, Nicolas Duployez, PharmD, PhD, Jane Churpek, MD, Kiran Tawana, MD, Erin Degelman, MSc, BSc, Georges Natsoulis, PhD, Monica L. Guzman, PhD, Mrinal M. Patnaik, MD MBBS, Akiko Shimamura, MD PhD, Alan B. Cantor, MD PhD, Tim Ripperger, MD PhD, Brigitte Schlegelberger, MD PhD, Doris Steinemann, PhD, Courtney D. DiNardo, MD MSc, Cristina Mecucci, MD PhD, Elvira DRP Velloso, MD PhD, Fabio PS Santos, MD, Marcela CA Silva, Uma Borate, MD, Shannon K. McWeeney, PhD, Grzegorz Nalepa, MD PhD, Susanne Ragg, MD PhD, Erika Mijin Kwon, PhD, Anupriya Agarwal, PhD, Stephen Langabeer, PhD, Jeffery M. Klco, MD PhD, Jun J. Yang, PhD, Cecily Forsyth, FRACP, FRCPA, MBBS, Sally Mapp, MD PhD, Helen Mar Fan, MD, Lesley Rawlings, PhD, Rachel Susman, Sue Morgan, FRACP, FRCPA, MBBS, Andrew H Wei, MBBS,PhD, Inderjeet Dokal, MD, Tom Vulliamy, Devendra K Hiwase, MBBS, MD FRACP, FRCPA, PhD, Deepak Singhal, MBBS, MD FRACP, FRCPA, Susan Branford, PhD, Elli Papaemmanuil, PhD, Jean Soulier, MDPhD, Stefan Fröhling, MD, Alwin Kramer, MD, Guy Sauvageau, MD PhD, Neil Morgan, Carolyn Owen, Csaba Bödör, PhD, Jude Fitzgibbon, Hugh Y. Rienhoff, Jr., MD, Mineo Kurokawa, MD PhD, Lucy Godley, MD PhD, Claude Preudhomme, Paul P Liu, MD PhD, Nicola Poplawski, MD, Christopher N. Hahn, PhD, Hamish S. Scott, PhD

Blood (2018) 132 (Supplement 1): 5241.

https://doi.org/10.1182/blood-2018-99-118017

Published: 2018

Journal Articles

Transcriptional Signaling Centers Govern Human Erythropoiesis and Harbor Genetic Variations of Red Blood Cell Traits

Blood (2018) 132 (Supplement 1): 1277.

https://doi.org/10.1182/blood-2018-99-118637

Published: 2018

Journal Articles

Examining the CREB Transcriptional Program in Erythropoiesis

Jacky Chung, PhD, Barry H. Paw, MD PhD, Harvey Lodish, PhD, Alireza Ghamari, PhD, Alan B. Cantor, MD, PhD

Blood (2017) 130 (Supplement 1): 933.

https://doi.org/10.1182/blood.V130.Suppl_1.933.933

Published: 2017

Journal Articles

Distinct Signaling Centers Define Stages of Human Erythropoiesis and Harbor Common Variations of Red Blood Cell Traits

Avik Choudhuri, PhD, Eirini Trompouki, PhD, Brian J Abraham, PhD, William Mallard, Min-Lee Yang, PhD, Alireza Ghamari, PhD, Kanen Hoi, Barbara Hummel, Sonja Boatman, Victoria Chan, Teresa V. Bowman, PhD, Song Yang, Yi Zhou, Sinichiro Takahashi, MD PhD, Alan B. Cantor, MD, PhD, Santhi Ganesh, MD, John Rinn, PhD, Richard A. Young, PhD, Leonard I. Zon, MD

Blood (2017) 130 (Supplement 1): 773.

https://doi.org/10.1182/blood.V130.Suppl_1.773.773

Published: 2017

Journal Articles

Regulation of Lysyl Oxidase, a Key Regulator of Bone Marrow Fibrosis, in Myelofibrosis

Orly Leiva, BS, Alan B. Cantor, MD, PhD, Philip Trackman, PhD, Katya Ravid, PhD DSc

Blood (2017) 130 (Supplement 1): 1662.

https://doi.org/10.1182/blood.V130.Suppl_1.1662.1662

Published: 2017

Journal Articles

Choosing wisely: RUNX1 alternate promoter use

Alan B. Cantor

Blood (2017) 130 (3): 236–237.

https://doi.org/10.1182/blood-2017-06-786228

Published: 2017

Journal Articles

GATA Factor Switching during Erythroid Differentiation Is Facilitated By FBW7 Mediated Clearance of GATA2

Alireza Ghamari, Gabriela Pregerning, Ernest Fraenkel, Alan B. Cantor

Blood (2016) 128 (22): 1479.

https://doi.org/10.1182/blood.V128.22.1479.1479

Published: 2016

Journal Articles

Erythropoietin Signaling Regulates Heme Biosynthesis

Jacky Chung, PhD, Johannes G. Wittig, Alireza Ghamari, Manami Maeda, MD, PhD, Harvey Lodish, PhD, Daniel E. Bauer, MD, PhD, Stuart H. Orkin, MD, Alan B. Cantor, MD, PhD, Takahiro Maeda, MD PhD, Harry A. Dailey, PhD, Barry H. Paw, MD, PhD

Blood (2016) 128 (22): 543.

https://doi.org/10.1182/blood.V128.22.543.543

Published: 2016

Journal Articles

RUNX1 Is a Candidate Transcriptional Effector in Juvenile Myelomonocytic Leukemia

Elisa Dorantes Acosta, MD PhD, Hui Huang, PhD, Sara P. Garcia, PhD, Elliot Stieglitz, MD, Mignon L. Loh, MD, G C Yuan, Alan B. Cantor

Blood (2016) 128 (22): 2699.

https://doi.org/10.1182/blood.V128.22.2699.2699

Published: 2016

Journal Articles

Erythroid Cells Adapt to L-Leucine Scarcity By Reducing Hemoglobin Production Via the mTORC1/4E-BP Pathway

Jacky Chung, PhD, Daniel E. Bauer, MD, PhD, Alireza Ghamari, PhD, Christopher P. Nizzi, M.Sc., Kathryn M. Deck, PhD, Paul D. Kingsley, PhD, Yvette Y. Yien, PhD, Nicholas C. Huston, B.A., Caiyong Chen, PhD, Johannes G. Wittig, B.Sc., James Palis, MD, Stuart H. Orkin, MD, Harvey F. Lodish, PhD, Richard S. Eisenstein, PhD, Alan B. Cantor, Barry H. Paw, MD PhD

Blood (2014) 124 (21): 2660.

https://doi.org/10.1182/blood.V124.21.2660.2660

Published: 2014

Journal Articles

An SCF-FBXW7 Ubiquitin Ligase Mediated Feedback Loop Facilitates GATA Factor Switching and Reinforces Commitment to Terminal Erythroid Maturation

Alireza Ghamari, Elizabeth Jaensch, Richard Giadone, Thomas E Akie, Jian Xu, PhD, Daniel Bauer, Stuart H. Orkin, MD, Alan B. Cantor

Blood (2014) 124 (21): 245.

https://doi.org/10.1182/blood.V124.21.245.245

Published: 2014

Journal Articles

Validating The Prognostic Significance Of FCRL2 In Predicting IGHV Mutation Status, Clinical Disease Progression, and Survival In CLL

Fu Jun Li, MD, PhD, Alan B Cantor, PhD, Mikhail A. Shakhmatov, MD, Ran Li, MD, Xiao-Jie Yan, MD PhD, Nicholas Chiorazzi, MD, Randall S. Davis, MD

Blood (2013) 122 (21): 4140.

https://doi.org/10.1182/blood.V122.21.4140.4140

Published: 2013

Journal Articles

Tmem14c Plays An Essential Role In Mitochondrial Heme Metabolism

Blood (2013) 122 (21): 427.

https://doi.org/10.1182/blood.V122.21.427.427

Published: 2013

Journal Articles

Src Kinase Can Activate RUNX1 Activity Via Phosphorylation Of C-Terminal Tyrosines and Activated RUNX1 Stimulates Granulopoiesis

Alan D. Friedman, M.D., Wan Yee Leong, M.Sc., Hong Guo, M.D., Ph.D., Ou Ma, Ph.D., Alan B. Cantor, M.D., Ph.D., Hui Huang, Ph.D.

Blood (2013) 122 (21): 1210.

https://doi.org/10.1182/blood.V122.21.1210.1210

Published: 2013

Journal Articles

Potential Role Of RUNX1 In The Pathogenesis Of Juvenile Myelomonocytic Leukemia (JMML)

Hui Huang, PhD, Daniel E. Bauer, MD, PhD, Mignon L. Loh, MD, Govind Bhagat, MD, Alan B. Cantor, M.D., Ph.D., Andrew L. Kung, MD, PhD

Blood (2013) 122 (21): 45.

https://doi.org/10.1182/blood.V122.21.45.45

Published: 2013

NARROW

Blood Flow Directs Yap/Taz-Mediated Transcriptional Regulation of Self-Renewal Programs to Control Developmental HSPC Expansion By Mechanical Stimulation of Piezo1

Somatic Mutational Landscape of Hereditary Hematopoietic Malignancies Associated with Germline Variants in RUNX1 , GATA2 and DDX41

Germline GATA1s-generating mutations predispose to leukemia with acquired trisomy 21 and Down syndrome-like phenotype

Profound intravascular hemolysis due to clostridial sepsis in an infant with necrotizing enterocolitis

Cell Cycle Regulates Phosphorylation of RUNX1 to Modulate Megakaryocyte-Erythroid Progenitor Fate Specification

Development of a Data Portal for Aggregation and Analysis of Genomics Data in Familial Platelet Disorder with Predisposition to Myeloid Malignancy - the RUNX1.DB

Transcriptional Signaling Centers Govern Human Erythropoiesis and Harbor Genetic Variations of Red Blood Cell Traits

Examining the CREB Transcriptional Program in Erythropoiesis

Distinct Signaling Centers Define Stages of Human Erythropoiesis and Harbor Common Variations of Red Blood Cell Traits

Regulation of Lysyl Oxidase, a Key Regulator of Bone Marrow Fibrosis, in Myelofibrosis

Choosing wisely: RUNX1 alternate promoter use

GATA Factor Switching during Erythroid Differentiation Is Facilitated By FBW7 Mediated Clearance of GATA2

Erythropoietin Signaling Regulates Heme Biosynthesis

RUNX1 Is a Candidate Transcriptional Effector in Juvenile Myelomonocytic Leukemia

Erythroid Cells Adapt to L-Leucine Scarcity By Reducing Hemoglobin Production Via the mTORC1/4E-BP Pathway

An SCF-FBXW7 Ubiquitin Ligase Mediated Feedback Loop Facilitates GATA Factor Switching and Reinforces Commitment to Terminal Erythroid Maturation

Validating The Prognostic Significance Of FCRL2 In Predicting IGHV Mutation Status, Clinical Disease Progression, and Survival In CLL

Tmem14c Plays An Essential Role In Mitochondrial Heme Metabolism

Src Kinase Can Activate RUNX1 Activity Via Phosphorylation Of C-Terminal Tyrosines and Activated RUNX1 Stimulates Granulopoiesis

Potential Role Of RUNX1 In The Pathogenesis Of Juvenile Myelomonocytic Leukemia (JMML)

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American Society of Hematology

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American Society of Hematology

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