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Journal Articles

The Growth Kinetics of Clonal Hematopoiesis Inform Risk of Blood Cancer Progression

David J. Curtis, Nicholas C. Wong, Anna Leichter, Le T.P. Thao, James Phung, Andrew J Murphy, Moeen Riaz, Robert Sebra, Alexander G. Bick, John J. McNeil, Rory Wolfe, Robyn L. Woods, Paul Lacaze, Erica M. Wood, Zoe McQuilten

Blood (2022) 140 (Supplement 1): 8607–8608.

https://doi.org/10.1182/blood-2022-168526

Published: 2022

Journal Articles

Non-Linear Trajectories of the Epigenome during T-Cell Leukemogenesis Revealed By Analysis of a Mouse Model of Human ETP-ALL

Feng Yan, Cedric Tremblay, Francine Garret-Bakelman, Jesslyn Saw, Matthew P. McCormack, Shokoufeh Abdollahi, Pieter Van Vlierberghe, David Powell, Nicholas C. Wong, David J. Curtis

Blood (2022) 140 (Supplement 1): 5898–5899.

https://doi.org/10.1182/blood-2022-169201

Published: 2022

Journal Articles

Comprehensive Genomic Landscape and Clonal Architecture in Pediatric Patients with Monosomy 7

Tamara Westover, Sherif Abdelhamed, Emily Xiong, Michael P Walsh, Jing Ma, Jasmine C. Wong, Astrid Behnert, Mignon L. Loh, Kevin M. Shannon, Jeffery M. Klco

Blood (2022) 140 (Supplement 1): 5837–5838.

https://doi.org/10.1182/blood-2022-166915

Published: 2022

Journal Articles

The Effect of Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Aspirin on Clinical Outcomes in the Healthy Elderly: A Sub-Study of the Aspirin in Reducing Events in the Elderly (ASPREE) Randomized Controlled Trial

Zoe McQuilten, Nicholas C. Wong, Anna Leichter, Le T.P. Thao, James Phung, Andrew J Murphy, Moeen Riaz, Robert Sebra, Alexander G. Bick, John J. McNeil, Rory Wolfe, Robyn L. Woods, Paul Lacaze, Erica M. Wood, David J. Curtis

Blood (2022) 140 (Supplement 1): 2238–2239.

https://doi.org/10.1182/blood-2022-170761

Published: 2022

Journal Articles

Cost and Healthcare Utilization in Relapsed/Refractory Diffuse Large B-Cell Lymphoma: A Real-World Analysis of Medicare Beneficiaries Receiving Chimeric Antigen Receptor T-Cell Vs. Autologous and Allogeneic Hematopoietic Cell Transplants

Iman Mohammadi, PhD, Anna G Purdum, Pharmd MS, Anny C Wong, PhD, Amy Schroeder, BPharm, Karl M Kilgore, PhD, Gunjan L. Shah, MDMS

Blood (2020) 136 (Supplement 1): 4.

https://doi.org/10.1182/blood-2020-134828

Published: 2020

Journal Articles

Burden of Illness and Outcomes in the 2nd Line Treatment of Large B-Cell Lymphoma: A Real-World Comparison of Medicare Beneficiaries with and without Stem Cell Transplants

Karl M Kilgore, PhD, Anny C Wong, PhD, Julia Thornton Snider, PhD, Paul Cheng, MDPhD, Amy Schroeder, BPharm, Iman Mohammadi, PhD

Blood (2020) 136 (Supplement 1): 1–2.

https://doi.org/10.1182/blood-2020-134812

Published: 2020

Journal Articles

The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1

Blood (2020) 136 (8): 957–973.

https://doi.org/10.1182/blood.2019002548

Published: 2020

Includes: Supplemental data

Journal Articles

Genetic disruption of N-Ras G12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice

Noemi A. Zambetti, Ari J. Firestone, Jarrett R. Remsberg, Benjamin J. Huang, Jasmine C. Wong, Amanda M. Long, Marina Predovic, Radu M. Suciu, Anagha Inguva, Scott C. Kogan, Kevin M. Haigis, Benjamin F. Cravatt, Kevin Shannon

Blood (2020) 135 (20): 1772–1782.

https://doi.org/10.1182/blood.2019003530

Published: 2020

Includes: Supplemental data

Journal Articles

Iron Overload in Patients Aged 60 Years and Older with Acute Myeloid Leukemia May Impact Adversely on Overall Survival

Colleen A. C. Wong, Chantal Leger, MD FRCPC, Heather A. Leitch, MD

Blood (2018) 132 (Supplement 1): 3982.

https://doi.org/10.1182/blood-2018-99-112307

Published: 2018

Journal Articles

Regulation of Cytokines/Chemokines Release and Anti-Tumor Effect of Expanded Natural Killer (NK) Cells By a Novel Fusion of N-820 (2B8T2M), an IL-15 Superagonist with 4 Single-Chain Anti-CD20 Antibody Domains, Against Rituximab Resistant Burkitt Lymphoma (BL)

Yaya Chu, PhD, Nang Kham Su, MS, Emily K Jeng, Sarah Alter, PhD, Peter R Rhode, PhD, John H Lee, MD, Gaurav Nayyar, MD PhD, Matthew J. Barth, MD, Dean Anthony Lee, MD PhD, Hing C Wong, PhD, Mitchell Cairo, MD

Blood (2018) 132 (Supplement 1): 3697.

https://doi.org/10.1182/blood-2018-99-117683

Published: 2018

Journal Articles

Plerixafor effectively mobilizes CD56 bright NK cells in blood, providing an allograft predicted to protect against GVHD

Peggy P. C. Wong, Amina Kariminia, David Jones, Connie J. Eaves, Ronan Foley, Sabine Ivison, Stephen Couban, Kirk R. Schultz

Blood (2018) 131 (25): 2863–2866.

https://doi.org/10.1182/blood-2018-03-836700

Published: 2018

Journal Articles

First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation

Blood (2018) 131 (23): 2515–2527.

https://doi.org/10.1182/blood-2017-12-823757

Published: 2018

Includes: Supplemental data

Journal Articles

Attenuated Protein Synthesis Drives the Hematopoietic Defects in Shwachman-Diamond Syndrome

Pekka Jaako, PhD, Chi C Wong, PhD MD, David Adams, PhD, Alan J. Warren, PhD FRCP, FRCPath

Blood (2017) 130 (Supplement 1): 876.

https://doi.org/10.1182/blood.V130.Suppl_1.876.876

Published: 2017

Journal Articles

Iron Overload in Lower International Prognostic Scoring System Risk Myelodysplastic Syndromes Patients Receiving Red Blood Cell Transfusions: Relation to Infection and Possible Benefit of Iron Chelation Therapy

Colleen A. C. Wong, Shannon A. Y. Wong, Heather A. Leitch, MD

Blood (2017) 130 (Supplement 1): 2986.

https://doi.org/10.1182/blood.V130.Suppl_1.2986.2986

Published: 2017

Journal Articles

First-in-Human Clinical Trial of the IL-15 Super-Agonist Complex ALT-803 for Patients Relapsed after Allogeneic Hematopoietic Cell Transplantation

Rizwan Romee, MD, Sarah Cooley, MD, Melissa Berrien-Elliott, PhD, Peter Westervelt, MDPhD, Michael R Verneris, MD, John E. Wagner, MD, Daniel J. Weisdorf, MD, Bruce Blazar, MD, John F DiPersio, MD PhD, Amanda F. Cashen, MD, Emily K Jeng, Amy Rock, Hing C Wong, PhD, Todd A. Fehniger, MDPhD, Jeffrey S. Miller, MD

Blood (2017) 130 (Supplement 1): 274.

https://doi.org/10.1182/blood.V130.Suppl_1.274.274

Published: 2017

Journal Articles

Therapeutic Effects of a Novel Fusion of ALT-803, an IL-15 Superagonist, with 4 Single-Chains of Anti-CD20 Antibody (2B8T2M) in Combination with Expanded Natural Killer Cells Against Rituximab Sensitive and Resistant Burkitt Lymphoma (BL)

Yaya Chu, PhD, Nang Kham Su, BS, Sarah Alter, PhD, Emily K Jeng, Peter R Rhode, PhD, Matthew J. Barth, MD, Dean Anthony Lee, MD PhD, Hing C Wong, PhD, Mitchell S. Cairo, MD

Blood (2017) 130 (Supplement 1): 3587.

https://doi.org/10.1182/blood.V130.Suppl_1.3587.3587

Published: 2017

Journal Articles

The IL15 Superagonist Complex ALT-803 Potently Enhances the Proliferative Capacity and Activity of in Vitro Expanded Natural Killer Cells

Tarun K. Garg, PhD, Katie Stone, BS, Amy Greenway, Carolina D. Schinke, MD, Sharmilan Thanendrarajan, MD, Maurizio Zangari, MD, Joshua Epstein, DSc, Brian A Walker, PhD, Hing C Wong, PhD, Emily K Jeng, Niraj Shrestha, Faith E Davies, MD, Gareth J. Morgan, MD PhD, Frits van Rhee, MD PhD

Blood (2017) 130 (Supplement 1): 5452.

https://doi.org/10.1182/blood.V130.Suppl_1.5452.5452

Published: 2017

Journal Articles

Genetic Validation of the Palmitoylation/Depalmitoylation Cycle As a Drug Target in NRAS Mutant Hematologic Malignancies In Vivo

Noemi A. Zambetti, PhD, Ari J. Firestone, PhD, Jasmine C. Wong, PhD, Amanda Long, BA, Anagha Inguva, BA, Radu M. Suciu, B.Sc., Benjamin F. Cravatt, PhD, Kevin M. Haigis, PhD, Kevin M. Shannon, MD

Blood (2017) 130 (Supplement 1): 1221.

https://doi.org/10.1182/blood.V130.Suppl_1.1221.1221

Published: 2017

Journal Articles

Resistant T-Cell Acute Lymphoblastic Leukemias That Emerge after In Vivo Treatment with Dexamethasone Frequently Down-Regulate Glucocorticoid Receptor Protein Expression

Blood (2016) 128 (22): 753.

https://doi.org/10.1182/blood.V128.22.753.753

Published: 2016

Journal Articles

Therapeutic Effects of ALT-803, an IL-15 Superagonist, in Combination with Anti-CD20 Chimeric Antigen Receptor Modified Expanded Natural Killer CELLS Against Pediatric Burkitt Lymphoma (BL)

Yaya Chu, PhD, Fangyu Lee, Janet Ayello, MS, Brian Hang, Melanie Zhang, Hing C. Wong, Dean A Lee, MDPhD, Mitchell S. Cairo, MD

Blood (2015) 126 (23): 3085.

https://doi.org/10.1182/blood.V126.23.3085.3085

Published: 2015

NARROW

The Growth Kinetics of Clonal Hematopoiesis Inform Risk of Blood Cancer Progression

Non-Linear Trajectories of the Epigenome during T-Cell Leukemogenesis Revealed By Analysis of a Mouse Model of Human ETP-ALL

Comprehensive Genomic Landscape and Clonal Architecture in Pediatric Patients with Monosomy 7

The Effect of Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Aspirin on Clinical Outcomes in the Healthy Elderly: A Sub-Study of the Aspirin in Reducing Events in the Elderly (ASPREE) Randomized Controlled Trial

Cost and Healthcare Utilization in Relapsed/Refractory Diffuse Large B-Cell Lymphoma: A Real-World Analysis of Medicare Beneficiaries Receiving Chimeric Antigen Receptor T-Cell Vs. Autologous and Allogeneic Hematopoietic Cell Transplants

Burden of Illness and Outcomes in the 2nd Line Treatment of Large B-Cell Lymphoma: A Real-World Comparison of Medicare Beneficiaries with and without Stem Cell Transplants

The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1

Genetic disruption of N-Ras G12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice

Iron Overload in Patients Aged 60 Years and Older with Acute Myeloid Leukemia May Impact Adversely on Overall Survival

Regulation of Cytokines/Chemokines Release and Anti-Tumor Effect of Expanded Natural Killer (NK) Cells By a Novel Fusion of N-820 (2B8T2M), an IL-15 Superagonist with 4 Single-Chain Anti-CD20 Antibody Domains, Against Rituximab Resistant Burkitt Lymphoma (BL)

Plerixafor effectively mobilizes CD56 bright NK cells in blood, providing an allograft predicted to protect against GVHD

First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation

Attenuated Protein Synthesis Drives the Hematopoietic Defects in Shwachman-Diamond Syndrome

Iron Overload in Lower International Prognostic Scoring System Risk Myelodysplastic Syndromes Patients Receiving Red Blood Cell Transfusions: Relation to Infection and Possible Benefit of Iron Chelation Therapy

First-in-Human Clinical Trial of the IL-15 Super-Agonist Complex ALT-803 for Patients Relapsed after Allogeneic Hematopoietic Cell Transplantation

Therapeutic Effects of a Novel Fusion of ALT-803, an IL-15 Superagonist, with 4 Single-Chains of Anti-CD20 Antibody (2B8T2M) in Combination with Expanded Natural Killer Cells Against Rituximab Sensitive and Resistant Burkitt Lymphoma (BL)

The IL15 Superagonist Complex ALT-803 Potently Enhances the Proliferative Capacity and Activity of in Vitro Expanded Natural Killer Cells

Genetic Validation of the Palmitoylation/Depalmitoylation Cycle As a Drug Target in NRAS Mutant Hematologic Malignancies In Vivo

Resistant T-Cell Acute Lymphoblastic Leukemias That Emerge after In Vivo Treatment with Dexamethasone Frequently Down-Regulate Glucocorticoid Receptor Protein Expression

Therapeutic Effects of ALT-803, an IL-15 Superagonist, in Combination with Anti-CD20 Chimeric Antigen Receptor Modified Expanded Natural Killer CELLS Against Pediatric Burkitt Lymphoma (BL)

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American Society of Hematology

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ASH Publications

American Society of Hematology

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