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Journal Articles

Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML

Brief Report
Zhihong Zeng, Dos D. Sarbassov, Ismael J. Samudio, Karen W. L. Yee, Mark F. Munsell, C. Ellen Jackson, Francis J. Giles, David M. Sabatini, Michael Andreeff, Marina Konopleva
Journal: Blood
Blood (2006) 109 (8): 3509–3512.
https://doi.org/10.1182/blood-2006-06-030833
Published: 2006
Includes: Supplemental data
Journal Articles

Blockade of adaptive defensive changes in cholesterol uptake and synthesis in AML by the addition of pravastatin to idarubicin + high-dose Ara-C: a phase 1 study

Clinical Trials & Observations
Steven M. Kornblau, Deborah E. Banker, Derek Stirewalt, Danny Shen, Elizabeth Lemker, Srdan Verstovsek, Zeev Estrov, Stefan Faderl, Jorge Cortes, Miloslav Beran, C. Ellen Jackson, Wenjing Chen, Elihu Estey, Frederick R. Appelbaum
Journal: Blood
Blood (2006) 109 (7): 2999–3006.
https://doi.org/10.1182/blood-2006-08-044446
Published: 2006
Includes: Supplemental data
Journal Articles

Rapamycin Analogs Reduce mTORC2 Signaling and Inhibit AKT Activation in AML.

Zhihong Zeng, PhD, Dos D. Sarbassov, Francis J. Giles, M.D., Ismael Samudio, Ph.D., Karen W.L. Yee, C. Ellen Jackson, R.N., B.S.N., David M. Sabatini, M.D., Ph.D., Michael Andreeff, M.D., Ph.D., Marina Konopleva, M.D., Ph.D.
Journal: Blood
Blood (2006) 108 (11): 156.
https://doi.org/10.1182/blood.V108.11.156.156
Published: 2006
Journal Articles

Simultaneous activation of multiple signal transduction pathways confers poor prognosis in acute myelogenous leukemia

Clinical Trials & Observations
Steven M. Kornblau, Matthew Womble, Yi Hua Qiu, C. Ellen Jackson, Wenjing Chen, Marina Konopleva, Elihu H. Estey, Michael Andreeff
Journal: Blood
Blood (2006) 108 (7): 2358–2365.
https://doi.org/10.1182/blood-2006-02-003475
Published: 2006
Includes: Supplemental data
Journal Articles

Blockade of Adaptive Defensive Changes in Cholesterol Uptake and Synthesis in AML by the Addition of Pravastatin to Idarubicin + High Dose Ara-C: A Phase I Study.

Steven M. Kornblau, MD, Deborah E. Banker, MD, Elizabeth Lemker, Zeev Estrov, MD, Stefan Faderl, MD, Srdan Verstovsek, MD, Jorge Cortes, MD, Guillermo Garcia-Manero, MD, Charles Koller, MD, Farhad Ravandi-Kashani, MD, Michael Andreeff, MD, PhD, C. Ellen Jackson, Wenjing Chen, Stephen Petersdorf, MD, Elihu Estey, MD, Frederick Appelbaum, MD
Journal: Blood
Blood (2005) 106 (11): 405.
https://doi.org/10.1182/blood.V106.11.405.405
Published: 2005
Journal Articles

2 Chlorodeoxyadenosine (2-CdA) and Cytarabine (ara-C) Combination Is Effective and Safe in Idiopathic Hypereosinophilic Syndrome (HES).

Elias Jabbour, M.D., Srdan Verstovsek, M.D., Ph.D., Varsha Gandhi, Ph.D., M.S., B.S., Jorge Cortes, M.D., Francis Giles, M.D., Charles Koller, M.D., Susan O’Brien, M.D., William Plunkett, Ph.D., Guillermo Garcia-Manero, M.D., Ellen Jackson, Hagop Kantarjian, M.D., Michael Andreeff, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 4764.
https://doi.org/10.1182/blood.V104.11.4764.4764
Published: 2004
Journal Articles

Inhibition of p53-MDM2 Interaction by Small-Molecule Antagonist of MDM2 Effectively Induces Apoptosis in Leukemias.

Kensuke Kojima, M.D., Ph.D., Marina Konopleva, M.D., Ph.D., Masato Shikami, M.D., Ph.D., Maria Cabreira-Hansen, Ph.D., C. Ellen Jackson, R.N., B.S.N., Elizabeth J. Shpall, M.D., Steven M. Kornblau, M.D., Lubo T. Vassilev, Ph.D., Michael Andreeff, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 2536.
https://doi.org/10.1182/blood.V104.11.2536.2536
Published: 2004
Journal Articles

Simultaneous Activation of Multiple Signal Transduction Pathways Confers Poor Prognosis in Acute Myelogenous Leukemia.

Steven M. Kornblau, M.D., Matthew Womble, Ellen Jackson, R.N., Weijing Chen, M.S., Elihu Estey, M.D., Michael Andreeff, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 2992.
https://doi.org/10.1182/blood.V104.11.2992.2992
Published: 2004
Journal Articles

Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia

Marina Konopleva, Twee Tsao, Peter Ruvolo, Irina Stiouf, Zeev Estrov, Clinton E. Leysath, Shourong Zhao, David Harris, Shirong Chang, C. Ellen Jackson, Mark Munsell, Nanjoo Suh, Gordon Gribble, Tadashi Honda, W. Stratford May, Michael B. Sporn, Michael Andreeff
Journal: Blood
Blood (2002) 99 (1): 326–335.
https://doi.org/10.1182/blood.V99.1.326
Published: 2002