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Irene Scarfò
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Journal Articles

Phase 1 study of CAR-37 T cells in patients with relapsed or refractory CD37 + lymphoid malignancies

Clinical Trials & Observations
Matthew J. Frigault, Charlotte E. Graham, Trisha R. Berger, Julie Ritchey, Nora K. Horick, Areej El-Jawahri, Irene Scarfò, Andrea Schmidts, Nicholas J. Haradhvala, Marc Wehrli, Won-Ho Lee, Aiyana L. Parker, Hadley R. Wiggin, Amanda Bouffard, Aonkon Dey, Mark B. Leick, Katelin Katsis, Eva L. Elder, Maria A. Dolaher, Daniella T. Cook, Alena A. Chekmasova, Lu Huang, Sarah Nikiforow, Heather Daley, Jerome Ritz, Myriam Armant, Fred Preffer, John F. DiPersio, Valentina Nardi, Yi-Bin Chen, Kathleen M. E. Gallagher, Marcela V. Maus
Journal: Blood
Blood (2024) 144 (11): 1153–1167.
https://doi.org/10.1182/blood.2024024104
Published: 2024
Includes: Supplemental data
Journal Articles

Combinatorial Effects of BH3 Mimetics and CAR T Cells Targeting T-Cell Lymphomas

Tayla B. Heavican-Foral, Felix Korell, Irene Scarfò, Harrison Silva, Allen Basanthakumar, Foster Powers, David M. Weinstock, Marcela V. Maus, Birgit Knoechel
Journal: Blood
Blood (2022) 140 (Supplement 1): 499–500.
https://doi.org/10.1182/blood-2022-159647
Published: 2022
Journal Articles

Blocking IFNγ in CAR-T Reduces Checkpoint Inhibitors and Cell-Mediated Toxicity without Compromising Therapeutic Efficacy in CD19 + malignancies

Stefanie R. Bailey, Sonika Vatsa, Rebecca Larson, Amanda A Bouffard, Irene Scarfò, Kathleen M.E. Gallagher, Matthew J. Frigault, Marcela V. Maus
Journal: Blood
Blood (2021) 138 (Supplement 1): 1723.
https://doi.org/10.1182/blood-2021-146042
Published: 2021
Journal Articles

Effects of Prior Exposure to Tec Kinase(BTK/ITK) Inhibitors on Kte-X19 Products

Irene Scarfò, Kathleen M.E. Gallagher, Mark B. Leick, Michael C. Kann, Justin Budka, Bharat Sowrirajan, Kim Nguyen, Rhine R. Shen, Adrian Bot, Marcela V. Maus
Journal: Blood
Blood (2021) 138 (Supplement 1): 3849.
https://doi.org/10.1182/blood-2021-146941
Published: 2021
Journal Articles

Phase 1 Study of CD37-Directed CAR T Cells in Patients with Relapsed or Refractory CD37+ Hematologic Malignancies

Matthew J. Frigault, Yi-Bin Chen, Kathleen M.E. Gallagher, Nora K. Horick, Areej El-Jawahri, Irene Scarfò, Marc Wehrli, Lu Huang, Keagan Casey, Daniella Cook, Thomas Spitzer, Steven McAfee, Frederic I. Preffer, Myriam Armant, Kit L. Shaw, Heather Daley, Sarah Nikiforow, Jerome Ritz, Marcela V. Maus
Journal: Blood
Blood (2021) 138 (Supplement 1): 653.
https://doi.org/10.1182/blood-2021-146236
Published: 2021
Journal Articles

Rational Chemical and Genetic Modifications Enhance Avidity and Function of CD70-Directed CAR-T-Cells for Myeloid Leukemia

Mark B. Leick, Harrison Silva, Irene Scarfò, Rebecca Larson, Bryan D. Choi, Amanda A Bouffard, Kathleen M.E. Gallagher, Andrea Schmidts, Stefanie R. Bailey, Michael C. Kann, Max Jan, Marc Wehrli, Korneel Grauwet, Matthew J. Frigault, Marcela V. Maus
Journal: Blood
Blood (2021) 138 (Supplement 1): 405.
https://doi.org/10.1182/blood-2021-150596
Published: 2021
Journal Articles

Tisagenlecleucel Demonstrates Safety, Efficacy and CNS Trafficking in Primary CNS Lymphoma

Matthew J. Frigault, Jorg Dietrich, Kathleen M.E. Gallagher, Irene Scarfò, Mark Roschewski, Justin T Jordan, Deborah A. Forst, Scott R Plotkin, Daniella Cook, Keagan Casey, Katelin Katsis, Kevin Lindell, Michael Trailor, Nora Horick, Steven McAfee, Paul V O'Donnell, Thomas R Spitzer, Bimalangshu R Dey, Zachariah Defilipp, Areej El-Jawahri, Tracy Batchelor, Marcela V. Maus, Yi-Bin Chen
Journal: Blood
Blood (2021) 138 (Supplement 1): 258.
https://doi.org/10.1182/blood-2021-148444
Published: 2021
Journal Articles

Use of CD70 Targeted Chimeric Antigen Receptor (CAR) T Cells for the Treatment of Acute Myeloid Leukemia (AML)

Mark Leick, MD, Irene Scarfò, PhD, Bryan D. Choi, MD PhD, Rebecca Larson, BS, Amanda A Bouffard, Ana Castano, MD, Maria L. Cabral, BS, Andrea Schmidts, MD, Matthew J. Frigault, MD, Marcela V. Maus, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4443.
https://doi.org/10.1182/blood-2019-127154
Published: 2019
Journal Articles

Application of a Standardized Flow Cytometry Panel for Defining and Monitoring the Immunophenotype of CAR-T Cells

Irene Scarfò, PhD, Kathleen Gallagher, Marcela V. Maus, MD PhD, Rebecca Larson, BS, Maegan Sheehan, BS, Gabrielle Brini, MSc, Scott Bornheimer, Mary Beth Hanley, Matthew Frigault, MD MSc, Mark Leick, MD, Alena Chekmasova, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5626.
https://doi.org/10.1182/blood-2019-128745
Published: 2019
Journal Articles

Engineering an Optimized Trimeric APRIL-Based CAR to Broaden Targetability of Multiple Myeloma

Andrea Schmidts, MD, Maria Ormhoj, MS, Allison O. Taylor, MS, Selena J. Lorrey, BA, Irene Scarfò, PhD, Matthew J. Frigault, MD, Bryan D. Choi, MD PhD, Marcela V. Maus, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2059.
https://doi.org/10.1182/blood-2018-99-119633
Published: 2018
Journal Articles

Anti-CD37 chimeric antigen receptor T cells are active against B- and T-cell lymphomas

Irene Scarfò, Maria Ormhøj, Matthew J. Frigault, Ana P. Castano, Selena Lorrey, Amanda A. Bouffard, Alexandria van Scoyk, Scott J. Rodig, Alexandra J. Shay, Jon C. Aster, Frederic I. Preffer, David M. Weinstock, Marcela V. Maus
Journal: Blood
Blood (2018) 132 (14): 1495–1506.
https://doi.org/10.1182/blood-2018-04-842708
Published: 2018
Includes: Supplemental data
Journal Articles

Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts

Irene Scarfò, Elisa Pellegrino, Elisabetta Mereu, Ivo Kwee, Luca Agnelli, Elisa Bergaggio, Giulia Garaffo, Nicoletta Vitale, Manuel Caputo, Rodolfo Machiorlatti, Paola Circosta, Francesco Abate, Antonella Barreca, Domenico Novero, Susan Mathew, Andrea Rinaldi, Enrico Tiacci, Sara Serra, Silvia Deaglio, Antonino Neri, Brunangelo Falini, Raul Rabadan, Francesco Bertoni, Giorgio Inghirami, Roberto Piva, the European T-Cell Lymphoma Study Group
Journal: Blood
Blood (2016) 127 (2): 221–232.
https://doi.org/10.1182/blood-2014-12-614503
Published: 2016
Includes: Supplemental data
Journal Articles

Identification of a New Subclass of ALK Negative Anaplastic Large Cell Lymphoma Expressing Aberrant Levels of ERBB4 Transcripts

Irene Scarfò, Elisa Pellegrino, Ivo Kwee, Luca Agnelli, Elisabetta Mereu, Elisa Bergaggio, Francesco Abate, Rodolfo Machiorlatti, Katia Messana, Andrea Rinaldi, Enrico Tiacci, Sara Serra, Silvia Deaglio, Antonino Neri, Brunangelo Falini, Raul Rabadan, Francesco Bertoni, Giorgio Inghirami, MD, Roberto Piva
Journal: Blood
Blood (2014) 124 (21): 1679.
https://doi.org/10.1182/blood.V124.21.1679.1679
Published: 2014