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Journal Articles

Updated Efficacy and Safety Results of Lisaftoclax (APG-2575) in Patients (Pts) with Heavily Pretreated Chronic Lymphocytic Leukemia (CLL): Pooled Analyses of Two Clinical Trials

Keshu Zhou, Mingyuan Sun, Xu Wei, Shuhua Yi, Junyuan Qi, Weiqi Nian, Guohui Cui, Jishi Wang, Xiaoping Zhang, Hong Cen, Fuling Zhou, Jianying Huang, Huilan Liu, Aizong Shen, Liangquan Geng, Ru Feng, Chongyuan Xu, Wenbin Qian, Fei Li, Lihong Liu, Caixia Li, Xielan Zhao, Jie Jin, Hongmei Jing, Dongmei Ji, Fangfang Lyu, Zi Chen, Lichuang Men, Hengbang Wang, Ke Zhang, Liang Xu, Zhang Zhang, Dajun Yang, Jianxiang Wang, Jianyong Li, Yifan Zhai
Journal: Blood
Blood (2023) 142 (Supplement 1): 1900.
https://doi.org/10.1182/blood-2023-183071
Published: 2023
Journal Articles

Subgroup Analysis from a Phase 2, Single-Arm Trial of the Oral PI3Kδ Inhibitor Linperlisib in Patients with Relapsed or Refractory Follicular Lymphoma

Tingyu Wang, Xiuhua Sun, Lihua Qiu, Hang Su, Junning Cao, Zhiming Li, Yuqin Song, Li Zhang, Dengju Li, Huijing Wu, Wei Zhang, Junmin Li, Keshu Zhou, Hui Zhou, Yu Yang, Zhifeng Li, Hong Cen, Zhen Cai, Zhihui Zhang, Weijun Fu, Jie Jin, IV, Fei Li, Weixin Wu, Xuekui Gu, Weiliang Zhu, Lihong Liu, Zengjun Li, Shuhua Yi, Hanying Bao, Zusheng Xu, Lugui Qiu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6145.
https://doi.org/10.1182/blood-2023-177820
Published: 2023
Journal Articles

A Prospective Multicenter Phase II Study of Orelabrutinib-Lenalidomide-Rituximab (OLR) in Patients with Untreated Mantle Cell Lymphoma (MCL) in China (POLARIS Study): Preliminary Analysis on Efficacy, Safety, Mutation Spectrum and Impact of Mutation Profiling on Treatment Responses

Huilai Zhang, Liping Su, Lihong Liu, Ou Bai, Zheng Song, Zhiqiang Zhao, Cuiying He, Qiang Guo, Xianhuo Wang, Wei Li, Lihua Qiu, Lanfang Li, Shiyong Zhou, Yue Fei, Xiaohui Wang, Bin Meng
Journal: Blood
Blood (2023) 142 (Supplement 1): 736.
https://doi.org/10.1182/blood-2023-178509
Published: 2023
Journal Articles

A Phase Ib Study of Linperlisib Monotherapy in Patients with Relapsed or Refractory B-Cell Malignancies

Wei Liu, Yunhong Huang, Haiyan Yang, Zhiming Li, Zhen Cai, Zhen Wang, Lihong Liu, Ye Guo, Ligen Liu, Rui Huang, Xu Ye, Lugui Qiu
Journal: Blood
Blood (2023) 142 (Supplement 1): 1722.
https://doi.org/10.1182/blood-2023-177550
Published: 2023
Journal Articles

A Multicenter, Open-Label, Single-Arm, Phase Ib Clinical Trial of HH2853 in the Treatment of Patients with Relapsed and/or Refractory Peripheral T-Cell Lymphoma

Huangming Hong, Mingzhi Zhang, Zhigang Peng, Jianzhen Shen, Yuerong Shuang, Hui Zhou, Hongqiang Guo, He Huang, Fei Li, Zhengzi Qian, Lihong Liu, Liang Wang, Wei Yang, Liling Zhang, Pengcheng He, Shen Qian, Fugen Li, Meng Li, Tongyu Lin
Journal: Blood
Blood (2023) 142 (Supplement 1): 304.
https://doi.org/10.1182/blood-2023-180372
Published: 2023
Journal Articles

Time to Lymphoma Treatment within 24 Months in Watchful Waiting Follicular Lymphoma Defines Patients at High Risk for Progression: A Multicenter Analysis

Fenghua Gao, Jing Liu, Jiesong Wang, Lihong Liu, Zhiming Li, Yuqin Song, Xudong Zhang, Hui Zhou, Xiuhua Sun, Wei Zhang, Bing Xu, Liping Su, Wen Shujuan, Rong Tao, Ou Bai, Qingyuan Zhang, Liqun Zou, Xianhuo Wang, Huilai Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4417.
https://doi.org/10.1182/blood-2023-174308
Published: 2023
Journal Articles

Loncastuximab Tesirine Demonstrated Substantial Single-Agent Efficacy and Manageable Safety Profile in Heavily Pretreated Chinese Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)

Ningjing Lin, Xiuhua Sun, Hui Zhou, Liqun Zou, Keshu Zhou, Lihong Liu, Haiyan Yang, Kai HU, Qingqing Cai, Yao Liu, Jie Jin, Liling Zhang, Wenyu Li, Ye Guo, Wei Yang, Feng Luo, Yanyan Li, Mengqi Zhang, Feinan Lu, Yuqin Song, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4469.
https://doi.org/10.1182/blood-2023-173645
Published: 2023
Journal Articles

PI3Kδ Inhibitor Linperlisib As a ≥ 3-Line Treatment for Relapsed or Refractory Follicular Lymphoma: A Subgroup Analysis of a Phase II, Single-Arm, Open-Label Trial

Hang Su, Tingyu Wang, Xiuhua Sun, Lihua Qiu, Junning Cao, Zhiming Li, Yuqin Song, Li Zhang, Dengju Li, Huijing Wu, Wei Zhang, Junmin Li, Keshu Zhou, Hui Zhou, Yu Yang, Zhifeng Li, Hong Cen, Zhen Cai, Zhihui Zhang, Weijun Fu, Jie Jin, IV, Fei Li, Weixin Wu, Xuekui Gu, Weiliang Zhu, Lihong Liu, Zengjun Li, Shuhua Yi, Hanying Bao, Zusheng Xu, Lugui Qiu
Journal: Blood
Blood (2023) 142 (Supplement 1): 1677.
https://doi.org/10.1182/blood-2023-178710
Published: 2023
Journal Articles

Dose Adjustments of Linperlisib in Relapsed or Refractory Follicular Lymphoma: A Post-Hoc Analysis of a Pivotal Phase II Study

Fangfang Lyu, Junning Cao, Tingyu Wang, Xiuhua Sun, Lihua Qiu, Hang Su, Zhiming Li, Yuqin Song, Li Zhang, Dengju Li, Huijing Wu, Wei Zhang, Junmin Li, Keshu Zhou, Hui Zhou, Yu Yang, Zhifeng Li, Hong Cen, Zhen Cai, Zhihui Zhang, Weijun Fu, Jie Jin, IV, Fei Li, Weixin Wu, Xuekui Gu, Weiliang Zhu, Lihong Liu, Zengjun Li, Shuhua Yi, Hanying Bao, Zusheng Xu, Lugui Qiu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6140.
https://doi.org/10.1182/blood-2023-180373
Published: 2023
Journal Articles

Orelabrutinib, Rituximab, and High-Dose Methotrexate (HD-MTX) in Newly Diagnosed Primary Central Nervous System Lymphoma (PCNSL): A Retrospective Analysis on Efficacy, Safety, and Biomarker

Shihua Zhao, Yao Liu, Zunmin Zhu, Jianxia He, Lihong Liu, Xiaobo Wang, Yuxia Zhao, Chongling Hu, Xiaoli Yuan, Sijun Bai, Ye Geng, Wenrong Huang
Journal: Blood
Blood (2022) 140 (Supplement 1): 1338–1339.
https://doi.org/10.1182/blood-2022-165710
Published: 2022
Journal Articles

Combination of Mitoxantrone Hydrochloride Liposome with Cyclophosphamide, Vincristine and Prednisone (CMOP) in Treatment-Naïve Patients with Peripheral T-Cell Lymphoma: A Multicenter, Open-Label, Single-Arm, Phase Ib Clinical Trial

Hui-Qiang Huang, Gao Yan, Ming Jiang, Lihong Liu, Qing Xiao, Yufu Li, Hui Zhou, Jianfei Xue, Dong Wang, Dapeng Xie, Honglian Li, Peng Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 3762–3763.
https://doi.org/10.1182/blood-2022-163343
Published: 2022
Journal Articles

Oligosecretory Waldenström Macroglobulinemia Patients Exhibit Excellent Treatment Response and Outcomes

Ying Yu, Wenjie Xiong, Zanzan Wang, Yuting Yan, Jiawen Chen, Yanshan Huang, Xinxin Cao, Zhongxing Jiang, Huihan Wang, Zhen Cai, Juan Du, Chunyan Sun, Ting Niu, Guangzhong Yang, Hua Xue, Bingzong Li, Honghui Huang, Zhenling Li, Qinhua Liu, Fei Li, Ou Bai, Min Mao, Rong Fu, Ling Wang, Chunrui Li, Xiaoxia Chu, Lihong Liu, Yujun Dong, Luqun Wang, Jun Luo, Yongqiang Wei, Lugui Qiu, Jian Li, ShuHua Yi
Journal: Blood
Blood (2022) 140 (Supplement 1): 9289–9291.
https://doi.org/10.1182/blood-2022-157311
Published: 2022
Journal Articles

Naturally Selected Anti-CD7 CAR-T Cells without Additional Genetic Manipulations As a Potentially Superior Therapy for T-Cell Malignancies

Ying Liu, Weijing Li, Lin Wang, Min Ba, Qinglong Wang, Peihua Lu, Lihong Liu, Jianqiang Li
Journal: Blood
Blood (2021) 138 (Supplement 1): 1696.
https://doi.org/10.1182/blood-2021-149384
Published: 2021
Journal Articles

Orelabrutinib Monotherapy in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: Updated Long Term Results of Phase II Study

Wei Xu, Yongping Song, Tingyu Wang, Shenmiao Yang, Lihong Liu, Yu Hu, Wei Zhang, Jianfeng Zhou, Sujun Gao, Kaiyang Ding, Huilai Zhang, Zunmin Zhu, Shunqing Wang, Bing Xu, Jianda Hu, Ting Liu, Chunyan Ji, Zhongjun Xia, Yan Li, Xin Wang, Bin Zhang, Renbin Zhao, Jianyong Li
Journal: Blood
Blood (2021) 138 (Supplement 1): 2638.
https://doi.org/10.1182/blood-2021-146491
Published: 2021
Journal Articles

A Phase1b Clinical Study of the Oral PI3Kδ Inhibitor, Linperlisib, in Patients with B-Cell Lymphomas

Lugui Qiu, Zhiming Li, Yunhong Huang, Ligen Liu, Lihong Liu, Ye Guo, Lan Deng, Haiyan Yang, Zhen CAI, Xu Ye, Zhen Wang, Hanying Bao, Zusheng Xu, Binghua Zheng
Journal: Blood
Blood (2021) 138 (Supplement 1): 3576.
https://doi.org/10.1182/blood-2021-148276
Published: 2021
Journal Articles

Waldenström's Macroglobulinaemia in the Modern Era: Real World Outcomes and Prognostication across 35 Chinese Academic Hospitals

Xin-xin Cao, MD, Shuhua Yi, MD, Zhongxing Jiang, MD, Jingsong He, MD, Wei Yang, Juan Du, Jr., MD, Chunyan Sun, MD PhD, Yu Wu, MD, Chen Wenming, MD, Xiao-jun Liu, Bingzong Li, MDPhD, Chunrui Li, MDPhD, Wei Sang, Qin-hua Liu, Xiaoxia Chu, Li Fei, Ou Bai, Min Mao, Rong Fu, PhD, Wei WANG, MD, Lihong Liu, MD, Luqun Wang, MDPhD, Yujun Dong, MD, Jun Luo, DO, Zhenling Li, Yongqiang Wei, Qi-ke Zhang, Jing Liu, Kaiyang Ding, Liang Zou, Bi-yun Chen, Luoming Hua, PhD, Hongmei Jing, Juan He, PhD, Liang Wang, Lugui Qiu, MD, Jian Li, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-134785
Published: 2020
Journal Articles

Long-Term Safety and Efficacy of Orelabrutinib Monotherapy in Chinese Patients with Relapsed or Refractory Mantle Cell Lymphoma: A Multicenter, Open-Label, Phase II Study

Yuqin Song, MD PhD, Yongping Song, MD, Lihong Liu, MD, Mingzhi Zhang, MD, Zhiming Li, MD PhD, Chunyan Ji, MD, Wei Xu, MD PhD, Ting Liu, MD PhD, Bing Xu, MD PhD, Xin Wang, MDPhD, Sujun Gao, Huilai Zhang, MD PhD, Yu Hu, MD, Yan Li, Ying Cheng, Haiyan Yang, MD PhD, Junning Cao, Zunmin Zhu, MD, Jianda Hu, MDPhD, Wei Zhang, Hongmei Jing, MD PhD, Kaiyang Ding, Zhengguang Lu, Bin Zhang, PhD, Renbin Zhao, PhD, Zhixin Xu, MD PhD, Jun Zhu, BS
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
https://doi.org/10.1182/blood-2020-141781
Published: 2020
Journal Articles

Updated Results from the Phase II Study of Orelabrutinib Monotherapy in Chinese Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Cell Leukemia

Wei Xu, MD PhD, Yongping Song, MD, Tingyu Wang, Shenmiao Yang, Lihong Liu, MD, Yu Hu, MD, Wei Zhang, Jianfeng Zhou, MD PhD, Sujun Gao, Kaiyang Ding, Huilai Zhang, MD PhD, Zunmin Zhu, MD, Shun-Qing Wang, Bing Xu, MD PhD, Jianda Hu, Ting Liu, MD PhD, Chunyan Ji, MD, Zhongjun Xia, MDPhD, Yan Li, PhDMD, Xin Wang, MDPhD, Huaqiang Zhu, MD, Renbin Zhao, PhD, Bin Zhang, PhD, Zhixin Xu, MD PhD, Jianyong Li, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–27.
https://doi.org/10.1182/blood-2020-134531
Published: 2020
Journal Articles

Gls-010, a Novel Anti-PD-1 Mab in Chinese Patients with Relapsed or Refractory Classical Hodgkin Lymphoma: Preliminary Impressive Results of a Phase II Clinical Trial

Yuqin Song, MD PhD, Jun Zhu, BS, Ningjing Lin, MD PhD, Mingzhi Zhang, MD, Hai Bai, MD, Hui Liu, MD, Jie Cui, MD, Xiaoyan Ke, MD, Huilai Zhang, MD PhD, Lihong Liu, MD, Dongmei Yan, MD, Yongsheng Jiang, MD, Aimin Zang, MD, Junyuan Qi, MD, Li Wang, MD, Zhuogang Liu, MD, Bing Xu, MD PhD, Ying Zhang, MD, Zhihui Zhang, MD PhD, Haijin Meng, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17.
https://doi.org/10.1182/blood-2020-136475
Published: 2020
Journal Articles

Pooled Analysis of Safety Data from Clinical Trials of Orelabrutinib Monotherapy in Hematologic Malignancies

Yuqin Song, MD PhD, Wei Xu, MD PhD, Yongping Song, MD, Lihong Liu, MD, Song Lin, Zhiming Li, MD PhD, Ting Liu, MD PhD, Shuhua Yi, MD, Daobin Zhou, MD PhD, Mingzhi Zhang, MD, Yu Hu, MD, Jie Jin, MD PhD, Huaqiang Zhu, MD, Zhengguang Lu, Renbin Zhao, PhD, Zhixin Xu, MD PhD, Jun Zhu, BS
Journal: Blood
Blood (2020) 136 (Supplement 1): 43.
https://doi.org/10.1182/blood-2020-140172
Published: 2020