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Journal Articles

First-in-Class JAK/Rock Inhibitor Rovadicitinib in Myeloproliferative Neoplasms: A Single Arm, Multicenter, Open-Label, Phase I/Ib Study

Zefeng Xu, Ling Pan, Zhenya Hong, Qingsong Yin, Xuelan Zuo, Qin Wen, Fan Yu, Chunkang Chang, Wei Ling, Dong Wang, Dawei Ding, Zhijian Xiao
Journal: Blood
Blood (2023) 142 (Supplement 1): 1829.
https://doi.org/10.1182/blood-2023-178956
Published: 2023
Journal Articles

High Dimensional Single-Cell Profiling Identifies Immune and Metabolic Heterogeneity in Immune Thrombocytopenia

Li-Ping Yang, Hai-Xia Fu, Peng Zhao, Jin Wu, Qiu-Sha Huang, Yuan-Yuan Zhang, Jun Kong, Zhi-Dong Wang, Jing Liu, Kaiyan Liu, Xiao Jun Huang, Xiaohui Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 2585.
https://doi.org/10.1182/blood-2023-185457
Published: 2023
Journal Articles

The OTUD1-Notch2-ICD axis orchestrates allogeneic T cell–mediated graft-versus-host disease

Qiao Cheng, Dong Wang, Xiaoxuan Lai, Yin Liu, Yibo Zuo, Wenli Zhang, Lei Lei, Jia Chen, Hong Liu, Ying Wang, Haiyan Liu, Hui Zheng, Depei Wu, Yang Xu
Journal: Blood
Blood (2023) 141 (12): 1474–1488.
https://doi.org/10.1182/blood.2022017201
Published: 2023
Includes: Supplemental data
Journal Articles

Discovery of novel predisposing coding and noncoding variants in familial Hodgkin lymphoma

Jamie E. Flerlage, Jason R. Myers, Jamie L. Maciaszek, Ninad Oak, Sara R. Rashkin, Yawei Hui, Yong-Dong Wang, Wenan Chen, Gang Wu, Ti-Cheng Chang, Kayla Hamilton, Saima S. Tithi, Lynn R. Goldin, Melissa Rotunno, Neil Caporaso, Aurélie Vogt, Deborah Flamish, Kathleen Wyatt, Jia Liu, Margaret Tucker, Christopher N. Hahn, Anna L. Brown, Hamish S. Scott, Charles Mullighan, Kim E. Nichols, Monika L. Metzger, Mary L. McMaster, Jun J. Yang, Evadnie Rampersaud
Journal: Blood
Blood (2023) 141 (11): 1293–1307.
https://doi.org/10.1182/blood.2022016056
Published: 2023
Includes: Supplemental data
Journal Articles

Combination of Mitoxantrone Hydrochloride Liposome with Cyclophosphamide, Vincristine and Prednisone (CMOP) in Treatment-Naïve Patients with Peripheral T-Cell Lymphoma: A Multicenter, Open-Label, Single-Arm, Phase Ib Clinical Trial

Hui-Qiang Huang, Gao Yan, Ming Jiang, Lihong Liu, Qing Xiao, Yufu Li, Hui Zhou, Jianfei Xue, Dong Wang, Dapeng Xie, Honglian Li, Peng Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 3762–3763.
https://doi.org/10.1182/blood-2022-163343
Published: 2022
Journal Articles

The OTUD1-Notch2-ICD Axis Orchestrates Allogeneic T Cell-Mediated Graft-Versus-Host Disease

Qiao Cheng, Dong Wang, Yang Xu, Depei Wu
Journal: Blood
Blood (2022) 140 (Supplement 1): 12897.
https://doi.org/10.1182/blood-2022-165788
Published: 2022
Journal Articles

Chidamide Plus Prednisone, Cyclophosphamide, and Thalidomide (CPCT) for Relapsed or Refractory Peripheral T-Cell Lymphoma: A Multicenter Phase II Trial

Wei Xu, Jin-Hua Liang, Li Wang, Xiao-Dong Wang, Guohui Cui, Jianfeng Zhou, Jingyan Xu, Luqun Wang, Rong Liang, Bi-yun Chen, Jian Cheng, Jian-Yong Li
Journal: Blood
Blood (2022) 140 (Supplement 1): 9484–9486.
https://doi.org/10.1182/blood-2022-157014
Published: 2022
Journal Articles

A study of ruxolitinib response–based stratified treatment for pediatric hemophagocytic lymphohistiocytosis

Clinical Trials & Observations
Qing Zhang, Yun-Ze Zhao, Hong-Hao Ma, Dong Wang, Lei Cui, Wei-Jing Li, Ang Wei, Chan-Juan Wang, Tian-You Wang, Zhi-Gang Li, Rui Zhang
Journal: Blood
Blood (2022) 139 (24): 3493–3504.
https://doi.org/10.1182/blood.2021014860
Published: 2022
Includes: Supplemental data
Journal Articles

Transcriptomic landscape of circulating mononuclear phagocytes in Langerhans cell histiocytosis at the single-cell level

Hui Shi, Han He, Lei Cui, Egle Kvedaraite, Zhilei Bian, Tao Huang, Christopher Z. W. Lee, Zhigang Li, Jian He, Yandong Gong, Zongcheng Li, Jie Zhou, Yang Zeng, Xianlong Li, Yanli Ni, Zhijie Bai, Chen Liu, Na Li, Honghao Ma, Dong Wang, Yu Lan, Florent Ginhoux, Rui Zhang, Bing Liu
Journal: Blood
Blood (2021) 138 (14): 1237–1248.
https://doi.org/10.1182/blood.2020009064
Published: 2021
Includes: Supplemental data
Journal Articles

Regnase-1 suppresses TCF-1 + precursor exhausted T-cell formation to limit CAR–T-cell responses against ALL

Wenting Zheng, Jun Wei, Caitlin C. Zebley, Lindsay L. Jones, Yogesh Dhungana, Yong-Dong Wang, Jayadev Mavuluri, Lingyun Long, Yiping Fan, Ben Youngblood, Hongbo Chi, Terrence L. Geiger
Journal: Blood
Blood (2021) 138 (2): 122–135.
https://doi.org/10.1182/blood.2020009309
Published: 2021
Includes: Supplemental data
Journal Articles

FBXO11-mediated proteolysis of BAHD1 relieves PRC2-dependent transcriptional repression in erythropoiesis

Peng Xu, Daniel C. Scott, Beisi Xu, Yu Yao, Ruopeng Feng, Li Cheng, Kalin Mayberry, Yong-Dong Wang, Wenjian Bi, Lance E. Palmer, Moeko T. King, Hong Wang, Yuxin Li, Yiping Fan, Arno F. Alpi, Chunliang Li, Junmin Peng, James Papizan, Shondra M. Pruett-Miller, Ria Spallek, Florian Bassermann, Yong Cheng, Brenda A. Schulman, Mitchell J. Weiss
Journal: Blood
Blood (2021) 137 (2): 155–167.
https://doi.org/10.1182/blood.2020007809
Published: 2021
Includes: Supplemental data
Journal Articles

First China Approved Rituximab Biosimilar HLX01: Pharmacokinetics, Safety and Efficacy Comparison to Reference Rituximab in the Phase 3 Diffuse Large B-Cell Lymphoma Study

Yuankai Shi, MD PhD, Yongping Song, MD PhD, Yan Qin, MD PhD, Qingyuan Zhang, MD, Xiaohong Han, MD, Xiaonan Hong, MD, Dong Wang, MD, Xiaofeng Zeng, MD PhD, Pei Hu, MD PhD, Shuiyu Zhao, Kaka Y. Hong, MSSB, Chaoming Ma, Jiancheng Cheng, Peng Ting, PhD, Kevin Li, MD, Weidong Jiang, PhD, Scott Liu, PhD, Eugene Liu, MD PhD, Xin Zhang, MD, Katherine Chai, PhD MsLaw, Dan Yao, PhD, Alvin Y. Luk, PhDMBA
Journal: Blood
Blood (2019) 134 (Supplement_1): 2878.
https://doi.org/10.1182/blood-2019-130603
Published: 2019
Journal Articles

The global clonal complexity of the murine blood system declines throughout life and after serial transplantation

Miguel Ganuza, Trent Hall, David Finkelstein, Yong-Dong Wang, Ashley Chabot, Guolian Kang, Wenjian Bi, Gang Wu, Shannon McKinney-Freeman
Journal: Blood
Blood (2019) 133 (18): 1927–1942.
https://doi.org/10.1182/blood-2018-09-873059
Published: 2019
Includes: Supplemental data
Journal Articles

The DNA Methylation Maintenance Protein UHRF1 Regulates Fetal Globin Expression Independent of HBG Promoter DNA Methylation

Ruopeng Feng, PhD, Phillip A Doerfler, PhD, Yu Yao, MD, Xing Tang, PhD, Yong-Dong Wang, PhD, Chunliang Li, PhD, David E. Root, PhD, Yong Cheng, PhD, Mitchell J. Weiss, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 410.
https://doi.org/10.1182/blood-2018-99-115589
Published: 2018
Journal Articles

FBXO11 Activates Erythroid Gene Transcription By Degrading Heterochromatin-Associated Protein BAHD1

Peng Xu, PhD, Daniel C. Scott, PhD, Xing Tang, PhD, Yu Yao, MD, Yong-Dong Wang, PhD, Wenjian Bi, PhD, Lance E. Palmer, PhD, Ruopeng Feng, PhD, Arno F. Alpi, PhD, Chunliang Li, PhD, Yong Cheng, PhD, Brenda A. Schulman, PhD, Mitchell J. Weiss, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 529.
https://doi.org/10.1182/blood-2018-99-117362
Published: 2018
Journal Articles

Myeloid-Derived Suppressor Cells (HLA-DR -/low CD16 - CD33 + ) Expanded By Granulocyte Colony-Stimulating Factor Can Prevent Acute Graft-Versus-Host Disease in Humanized Mouse and Patients Following HSCT

Ke Wang, Meng Lv, Ying-Jun Chang, Xiang-Yu Zhao, Xiao-Su Zhao, Yuan-Yuan Zhang, Yu-Qian Sun, MD, Zhi-Dong Wang, Pan Suo, Yang Zhou, Dan Liu, Shu-Zhen Zhai, Yan Hong, Yu Wang, Xiao-Hui Zhang, Lan-Ping Xu, Kaiyan Liu, MD PhD, Xiao-Jun Huang
Journal: Blood
Blood (2018) 132 (Supplement 1): 72.
https://doi.org/10.1182/blood-2018-99-114291
Published: 2018
Journal Articles

Genomic Profiling Identifies Novel Mutations and Fusion Genes in Newly Diagnosed and Relapsed Pediatric FLT3-ITD-Positive AML

Daelynn R Buelow, PhD, Stanley Pounds, PhD, Yong-Dong Wang, Lei Shi, PhD, Yongjin Li, PhD, David Finkelstein, Sheila A Shurtleff, PhD, Geoffrey A. Neale, PhD, Hiroto Inaba, MD PhD, Raul C. Ribeiro, MD, Dominique Garrison, Shelley Orwick, BS, James S. Blachly, MD, John C. Byrd, MD, Karl Kroll, Tanja A. Gruber, MD PhD, Jeffrey E Rubnitz, MD PhD, Sharyn D Baker, PharmD, PhD
Journal: Blood
Blood (2016) 128 (22): 2838.
https://doi.org/10.1182/blood.V128.22.2838.2838
Published: 2016
Journal Articles

Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia

Elliot Stieglitz, Camille B. Troup, Laura C. Gelston, John Haliburton, Eric D. Chow, Kristie B. Yu, Jon Akutagawa, Amaro N. Taylor-Weiner, Y. Lucy Liu, Yong-Dong Wang, Kyle Beckman, Peter D. Emanuel, Benjamin S. Braun, Adam Abate, Robert B. Gerbing, Todd A. Alonzo, Mignon L. Loh
Journal: Blood
Blood (2015) 125 (3): 516–524.
https://doi.org/10.1182/blood-2014-09-601690
Published: 2015
Includes: Supplemental data
Journal Articles

Mito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice

XiuJie Li-Harms, Sandra Milasta, John Lynch, Christopher Wright, Aashish Joshi, Rekha Iyengar, Geoffrey Neale, Xi Wang, Yong-Dong Wang, Tomas A. Prolla, James E. Thompson, Joseph T. Opferman, Douglas R. Green, John Schuetz, Mondira Kundu
Journal: Blood
Blood (2015) 125 (1): 162–174.
https://doi.org/10.1182/blood-2014-07-586396
Published: 2015
Includes: Supplemental data
Journal Articles

Tyrosine Kinase Inhibitor (TKI) Combination Scheduling Impacts Secondary FLT3 Tyrosine Kinase Domain (TKD) Mutation Profiles in a Xenograft Model of FLT3-ITD+ Acute Myeloid Leukemia (AML)

Jolieke G van Oosterwijk, PhD, Eric I Zimmerman, PhD, Yong-Dong Wang, PhD, Shelley Orwick, Aksana Vasilyeva, PhD, Katja Schuster, PhD, Abhijit Ramachandran, PhD, Hiroto Inaba, MD PhD, Sharyn D Baker, PharmD, PhD
Journal: Blood
Blood (2014) 124 (21): 3620.
https://doi.org/10.1182/blood.V124.21.3620.3620
Published: 2014