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Mark B Leick
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Journal Articles

CD70 CAR T cells secreting an anti-CD33/anti-CD3 dual targeting antibody overcome antigen heterogeneity in AML

Harrison Silva, Grace Martin, Filippo Birocchi, Marc Wehrli, Michael C Kann, Valentina M Supper, Aiyana Parker, Charlotte E Graham, Alexandra Grace Bratt, Amanda A Bouffard, Hannah Donner, Giulia Escobar, Hana N Takei, Alexander Armstrong, Sadie Goncalves, Trisha R Berger, Bryan D. Choi, Marcela V Maus, Mark B Leick
Journal: Blood
Blood blood.2023023210.
https://doi.org/10.1182/blood.2023023210
Published: 2024
Includes: Supplemental data
Journal Articles

Phase 1 study of CAR-37 T cells in patients with relapsed or refractory CD37 + lymphoid malignancies

Clinical Trials & Observations
Matthew J. Frigault, Charlotte E. Graham, Trisha R. Berger, Julie Ritchey, Nora K. Horick, Areej El-Jawahri, Irene Scarfò, Andrea Schmidts, Nicholas J. Haradhvala, Marc Wehrli, Won-Ho Lee, Aiyana L. Parker, Hadley R. Wiggin, Amanda Bouffard, Aonkon Dey, Mark B. Leick, Katelin Katsis, Eva L. Elder, Maria A. Dolaher, Daniella T. Cook, Alena A. Chekmasova, Lu Huang, Sarah Nikiforow, Heather Daley, Jerome Ritz, Myriam Armant, Fred Preffer, John F. DiPersio, Valentina Nardi, Yi-Bin Chen, Kathleen M. E. Gallagher, Marcela V. Maus
Journal: Blood
Blood (2024) 144 (11): 1153–1167.
https://doi.org/10.1182/blood.2024024104
Published: 2024
Includes: Supplemental data
Journal Articles

Chemotherapy-induced reversal of ciltacabtagene autoleucel–associated movement and neurocognitive toxicity

Clinical Trials & Observations
Charlotte E. Graham, Won-Ho Lee, Hadley R. Wiggin, Valentina M. Supper, Mark B. Leick, Filippo Birocchi, Andrew J. Yee, Angelina Petrichenko, John Everett, Frederic D. Bushman, Hossein Sadrzadeh, Otto Rapalino, Daniel Chiu, Isabel Arrillaga-Romany, Marcela V. Maus, Matthew J. Frigault, Kathleen M. E. Gallagher
Journal: Blood
Blood (2023) 142 (14): 1248–1252.
https://doi.org/10.1182/blood.2023021429
Published: 2023
Includes: Supplemental data
Journal Articles

Patients with Deleterious Germline Variants in STXBP2 Develop Toxicity after CAR-T Cell Therapy with Axicabtagene Ciloleucel

Mark B. Leick, Seunghun Han, Kathleen M.E. Gallagher, Harrison Silva, Grace Martin, Sabrina Camp, Hoyin Chu, Riaz Gillani, Michael C. Kann, Bryan D. Choi, Rebecca Larson, Merle Phillips, Tamina Kienka, Stefanie R. Bailey, Charlotte Graham, Christopher R. Reilly, Max Jan, Elba Gonzalez, Nora K. Horick, Justin Budka, Simone Filosto, Rhine R. Shen, Eliezer Van Allen, Saud H AlDubayan, Marcela V. Maus
Journal: Blood
Blood (2022) 140 (Supplement 1): 646–647.
https://doi.org/10.1182/blood-2022-166322
Published: 2022
Journal Articles

Bispecific CD33/CD123 Targeted Chimeric Antigen Receptor T Cells for the Treatment of Acute Myeloid Leukemia

Justin C. Boucher, Bishwas Shrestha, Paresh Vishwasrao, Mark B. Leick, Nhan Tu, Tayyebb Ghafoor, Kayla M. Reid, Kristen Spitler, Bin Yu, Marcela V. Maus, Marco L. Davila
Journal: Blood
Blood (2022) 140 (Supplement 1): 10275–10276.
https://doi.org/10.1182/blood-2022-163299
Published: 2022
Journal Articles

Safety and efficacy of tisagenlecleucel in primary CNS lymphoma: a phase 1/2 clinical trial

Clinical Trials & Observations
Matthew J. Frigault, Jorg Dietrich, Kathleen Gallagher, Mark Roschewski, Justin T. Jordan, Deborah Forst, Scott R. Plotkin, Daniella Cook, Keagan S. Casey, Kevin A. Lindell, Gabriel D. Depinho, Katelin Katsis, Eva Lynn Elder, Mark B. Leick, Bryan Choi, Nora Horick, Frederic Preffer, Meredith Saylor, Steven McAfee, Paul V. O’Donnell, Thomas R. Spitzer, Bimalangshu Dey, Zachariah DeFilipp, Areej El-Jawahri, Tracy T. Batchelor, Marcela V. Maus, Yi-Bin Chen
Journal: Blood
Blood (2022) 139 (15): 2306–2315.
https://doi.org/10.1182/blood.2021014738
Published: 2022
Includes: Supplemental data
Journal Articles

Effects of Prior Exposure to Tec Kinase(BTK/ITK) Inhibitors on Kte-X19 Products

Irene Scarfò, Kathleen M.E. Gallagher, Mark B. Leick, Michael C. Kann, Justin Budka, Bharat Sowrirajan, Kim Nguyen, Rhine R. Shen, Adrian Bot, Marcela V. Maus
Journal: Blood
Blood (2021) 138 (Supplement 1): 3849.
https://doi.org/10.1182/blood-2021-146941
Published: 2021
Journal Articles

Rational Chemical and Genetic Modifications Enhance Avidity and Function of CD70-Directed CAR-T-Cells for Myeloid Leukemia

Mark B. Leick, Harrison Silva, Irene Scarfò, Rebecca Larson, Bryan D. Choi, Amanda A Bouffard, Kathleen M.E. Gallagher, Andrea Schmidts, Stefanie R. Bailey, Michael C. Kann, Max Jan, Marc Wehrli, Korneel Grauwet, Matthew J. Frigault, Marcela V. Maus
Journal: Blood
Blood (2021) 138 (Supplement 1): 405.
https://doi.org/10.1182/blood-2021-150596
Published: 2021
Journal Articles

Antibody and T-Cell Responses to COVID-19 Vaccination in Myeloproliferative Neoplasm Patients

Joan How, Kathleen M.E. Gallagher, Yiwen Liu, Ashley DeMato, Katelin Katsis, Rebecca Larson, Mark B. Leick, Donna S. Neuberg, Marcela V. Maus, Gabriela Hobbs
Journal: Blood
Blood (2021) 138 (Supplement 1): 316.
https://doi.org/10.1182/blood-2021-145657
Published: 2021