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Michael A Rieger
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Journal Articles

Single Cell Analysis Identifies Expression of PD-L2 on Human Bone Marrow Hematopoietic Stem Cells

Tessa Schmachtel, Marius Külp, Weijia Yu, Hana Komic, Catia Simoes, Malin S. Nilsson, Felipe Prosper, Timm Schroeder, Halvard Bonig, Bruno Paiva, Fredrik B. Thorén, Michael A. Rieger
Journal: Blood
Blood (2023) 142 (Supplement 1): 2671.
https://doi.org/10.1182/blood-2023-188684
Published: 2023
Journal Articles

Early Molecular Steps in Human Bone Marrow Stem Cell Differentiation Trajectories

Hana Komic, Weijia Yu, Catia Simoes, Tessa Schmachtel, Malin S. Nilsson, Felipe Prosper, Bruno Paiva, Fredrik B. Thorén, Michael A. Rieger
Journal: Blood
Blood (2023) 142 (Supplement 1): 4047.
https://doi.org/10.1182/blood-2023-185490
Published: 2023
Journal Articles

CRISPR/Cas9 Gene Editing of Immune Checkpoint Receptor NKG2A Improves the Efficacy of Primary CD33-CAR-NK Cells Against AML

Nawid Albinger, Tobias Bexte, Leon Buchinger, Philipp Wendel, Ahmad Al-Ajami, Alec Gessner, Vinzenz Särchen, Jamal Alzubi, Sarah Mertlitz, Olaf Penack, Raj Bhayadia, Jan-Henning Klusmann, Meike Vogler, Nina Möker, Toni Cathomen, Michael A. Rieger, Katharina Imkeller, Evelyn Ullrich
Journal: Blood
Blood (2022) 140 (Supplement 1): 4558–4559.
https://doi.org/10.1182/blood-2022-169758
Published: 2022
Journal Articles

Portraying Immunity to Sars-Cov-2 after mRNA-Vaccination in Patients with Multiple Myeloma

Julius Christoph Enssle, Alina Moter, Julia Campe, Alec Gessner, Ika Weijia Yu, Sebastian Wolf, Björn Steffen, Hubert Serve, Melanie Bremm, Sabine Huenecke, Michael Lohoff, Maria Vehreschild, Holger F. Rabenau, Marek Widera, Sandra Ciesek, Michael A Rieger, Katharina Imkeller, Ivana von Metzler, Evelyn Ullrich
Journal: Blood
Blood (2022) 140 (Supplement 1): 1826–1827.
https://doi.org/10.1182/blood-2022-165871
Published: 2022
Journal Articles

Severe impairment of T-cell responses to BNT162b2 immunization in patients with multiple myeloma

Clinical Trials & Observations
Julius C. Enßle, Julia Campe, Amelie Schwenger, Eliza Wiercinska, Helen Hellstern, Ralf Dürrwald, Michael A. Rieger, Sebastian Wolf, Olivier Ballo, Björn Steffen, Hubert Serve, Halvard Bonig, Holger F. Rabenau, Marek Widera, Sandra Ciesek, Ivana von Metzler, Evelyn Ullrich
Journal: Blood
Blood (2022) 139 (1): 137–142.
https://doi.org/10.1182/blood.2021013429
Published: 2022
Includes: Supplemental data
Journal Articles

Identification of Prognostic Immunophenotypes at First Diagnosis in Patients with Acute Myeloid Leukemia (AML) By a Standardized Multicolor Flow Cytometry (MFC) Panel Originally Designed to Detect Measurable Residual Disease (MRD) at Follow-up

Maximilian Alexander A Rohnert, Malte von Bonin, Michael Kramer, Philipp Ensel, Nadja Holtschke, Christoph Rollig, MD MSC, Martin Bornhäuser, MD, Veit Buecklein, MD, Marion Subklewe, MD, Stefan W Krause, Simon Voelkl, Tobias Berg, Michael A Rieger, Cornelia Brendel, Jörg Hoffmann, Nicole Hofmeister-Mielke, Richard F. Schlenk, Sylvie D Freeman, Uta Oelschlägel
Journal: Blood
Blood (2020) 136 (Supplement 1): 35.
https://doi.org/10.1182/blood-2020-138683
Published: 2020
Journal Articles

No Evidence for Hematopoietic Stem Cell Self-Renewal in-Vivo Following Inflammatory Challenge

Ruzhica Bogeska, PhD, Paul Kaschutnig, PhD, Stella V Paffenholz, MSc, Julia Knoch, Jan-Philipp Mallm, PhD, Malak Fawaz, MSc, Florian Buettner, PhD, Dagmar Walter, PhD, Felix Frauhammer, MSc, Tim Holland-Letz, PhD, Noboru Asada, MD PhD, Ana-Matea Mikecin Drazic, PhD, Marleen Buechler-Schaff, MSc, Martha Correno-Gonzalez, Melanie Ball, Sina Staeble, MSc, Julius Gräsel, PhD, Simon Haas, PhD, Daniel B. Lipka, MD, Karsten Rippe, PhD, Benedikt Brors, PhD, Paul S. Frenette, MD, Michael A. Rieger, Marieke A. G. Essers, PhD, Michael D. Milsom, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 456.
https://doi.org/10.1182/blood-2019-125744
Published: 2019
Journal Articles

Active DNA Demethylation Mediated By GADD45β Is Essential during G-CSF Triggered Granulocytic Differentiation

Perihan Mir, Maksim Klimiankou, Narges Aghaallaei, Betuel Findik, Frederic Thalheimer, Susanne Wingert, Michael A. Rieger, Thomas Thumberger, Cornelia Zeidler, Baubak Bajoghli, Karl Welte, Julia Skokowa, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 211.
https://doi.org/10.1182/blood-2019-128508
Published: 2019
Journal Articles

Impact of KIR/HLA Incompatibilities after Posttransplant Cyclophosphamide Based T Cell-Replete Haploidentical Hematopoietic Stem Cell Transplantation

Sarah Lindner, MD, Tobias Berg, MD, Christian Seidel, Franziska Kalensee, Michael A. Rieger, Hubert Serve, MD, Gesine Bug, Joachim Schwaeble, Evelyn Ullrich, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3340.
https://doi.org/10.1182/blood-2019-125243
Published: 2019
Journal Articles

GADD45b Plays an Essential Role in the G-CSF Triggered Granulocytic Differentiation of Human Hematopoietic Cells

Perihan Mir, Masoud Nasri, Benjamin Dannenmann, Maksim Klimiankou, Betuel Findik, Regine Bernhard, Michael A. Rieger, Cornelia Zeidler, Lothar Kanz, Karl Welte, Julia Skokowa, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 17.
https://doi.org/10.1182/blood-2018-99-114875
Published: 2018
Journal Articles

Homocygous PAX5 Sequence Mutations Define a Novel Subtype of B Cell Precursor Acute Lymphoblastic Leukemia

Lorenz Bastian, Michael P Schroeder, PhD, Cornelia Eckert, PhD, Cornelia Schlee, Jutta Ortiz Tanchez, Sebastian Kämpf, Dimitrios L. Wagner, Veronika Schulze, Konstandina Isaakidis, Alva Rani James, Thomas Burmeister, Stefan Schwartz, MD, Sebastian Vosberg, Stefan Krebs, PhD, Helmut Blum, PhD, Jochen Hecht, PhD, Philipp A. Greif, MD, Michael A. Rieger, PhD, Monika Brüggemann, MD, Nicola Goekbuget, MD, Carsten Müller-Tidow, Hubert Serve, Martin Neumann, Claudia D. Baldus, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2713.
https://doi.org/10.1182/blood.V130.Suppl_1.2713.2713
Published: 2017
Journal Articles

Exploring the Function of Sestrin/Gator As Novel Regulators of Hematopoiesis

Nina Kurrle, PhD, Frank Schnütgen, PhD, Juliana Heidler, PhD, Ina Poser, PhD, Frank Wempe, PhD, Diego Yepes, PhD, Ilka Wittig, PhD, Thomas Oellerich, MD, Michael A Rieger, PhD, Harald von Melchner, MD PhD, Hubert Serve, MD
Journal: Blood
Blood (2016) 128 (22): 1484.
https://doi.org/10.1182/blood.V128.22.1484.1484
Published: 2016
Journal Articles

Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling By Suppression of Mir-146a in Acute Myeloid Leukemia

Sebastian Mohr, Carmen Doebele, PhD, Tobias Berg, MD, Federico Comoglio, PhD, Julia Beck, PhD, Gabriela Alexe, PhD, Jasmin Corso, Hanibal Bohnenberger, MD, Philipp Stroebel, MD, Astrid Wachter, Tim Beissbarth, PhD, Frank Schnuetgen, PhD, Nadine Haetscher, PhD, Stefanie Goellner, PhD, Arefeh Rouhi, PhD, Lars Palmqvist, MD PhD, Michael A Rieger, PhD, Carsten Mueller-Tidow, MD, Florian Kuchenbauer, Ekkehardt Schuetz, MD, Henning Urlaub, PhD, Kimberly Stegmaier, MD, R. Keith Humphries, MD PhD, Hubert Serve, MD, Thomas Oellerich, MD
Journal: Blood
Blood (2016) 128 (22): 1533.
https://doi.org/10.1182/blood.V128.22.1533.1533
Published: 2016
Journal Articles

The miRNA-193 Family Is a Potent Tumor-Suppressor and a Biomarker for Poor Prognosis in Acute Myeloid Leukemia

Razan Jammal, Kathrin Krowiorz, Nadine Haetscher, PhD, Stephan Emmrich, PhD MSc, Arefeh Rouhi, PhD, Michael Heuser, MD, Sabrina Bothur, Lars Bullinger, MD, Konstanze Döhner, Courteney Lai, Tobias Maetzig, Askar Obulkasim, Vera Martins, PhD, Medhanie A. Mulaw, Jun.-Prof. Dr., Jan Stary, MD D.Sc., Andre Baruchel, MD, Valerie De Haas, MD PhD, Dirk Reinhardt, MD PhD, Hartmut Döhner, MD, Jens Ruschmann, Michel Zwaan, Marry van den Heuvel-Eibrink, Dirk Heckl, PhD, Maarten Fornerod, PhD, R. Keith Humphries, MD PhD, Michael A Rieger, PhD, Florian Kuchenbauer, Jan-Henning Klusmann, MD
Journal: Blood
Blood (2016) 128 (22): 1534.
https://doi.org/10.1182/blood.V128.22.1534.1534
Published: 2016
Journal Articles

Transition out of HSC Dormancy By a Continuous Upregulation of Metabolism Is Controlled Via Dietary Vitamin A/ Retinoic Acid Signaling

Nina Cabezas-Wallscheid, Florian Buettner, Daniel Klimmeck, Pia Sommerkamp, Luisa Ladel, Frederic B Thalheimer, Simon Renders, Daniel Pastor, Leticia Roma, Petra Zeisberger, Adriana Przybylla, Roberta Scognamiglio, Sandro Altamura, Carolina M. Florian, Malak Fawaz, Dominik Vonficht, Paul Collier, Dinko Pavlinik, Hartmut Geiger, Timm Schröder, Vladimir Benes, Tobias P. Dick, Michael A Rieger, Oliver Stegle, Andreas Trumpp
Journal: Blood
Blood (2016) 128 (22): LBA-4.
https://doi.org/10.1182/blood.V128.22.LBA-4.LBA-4
Published: 2016
Journal Articles

Heterotrimeric G-Proteins Are Indispensable for FLT3-ITD autophosphorylation and Oncogenic Function

Maike Rehage, PhD, Susanne Wingert, PhD, Nadine Haetscher, PhD, Sabrina Bothur, Hubert Serve, MD, Manuel Grez, PhD, Joachim Schwaeble, MD, Michael A Rieger, PhD
Journal: Blood
Blood (2016) 128 (22): 2712.
https://doi.org/10.1182/blood.V128.22.2712.2712
Published: 2016
Journal Articles

Multi-Genomics of Relapsed B-Cell Precursor Acute Lymphoblastic Leukemia Reveals Three Distinct Genetic Clusters Characterized By Different Alterations

Michael P Schroeder, PhD, Martin Neumann, MD, Cornelia Eckert, PhD, Lorenz Bastian, MD, Alva Rani James, Nicola Gökbuget, MD, Cornelia Schlee, Jutta Ortiz Tanchez, Konstandina Isaakidis, Stefan Schwartz, MD, Thomas Burmeister, MD, Dieter Hoelzer, MD, Heike Pfeiffer, MD, Michael A Rieger, PhD, Stefanie Göllner, PhD, Thomas Oellerich, MD, Diego Yepes, PhD, Renate Kirschner-Schwabe, PhD, Monika Brüggemann, MD PhD, Carsten Müller-Tidow, Hubert Serve, MD, Claudia D. Baldus, MD
Journal: Blood
Blood (2016) 128 (22): 453.
https://doi.org/10.1182/blood.V128.22.453.453
Published: 2016
Journal Articles

The Gadd45 Family As Mediators of Hematopoietic Stem Cell Differentiation - from Genotoxic Stress to Cytokine-Induced Differentiation

Susanne Wingert, MSc, Frederic B Thalheimer, PhD, Nadine Haetscher, MSc, Maike Rehage, PhD, Hubert Serve, MD, Timm Schroeder, PhD, Michael A. Rieger, PhD
Journal: Blood
Blood (2015) 126 (23): 1188.
https://doi.org/10.1182/blood.V126.23.1188.1188
Published: 2015
Journal Articles

ATF4, a new player in fetal HSC expansion

Michael A. Rieger
Journal: Blood
Blood (2015) 126 (21): 2351–2352.
https://doi.org/10.1182/blood-2015-10-671370
Published: 2015
Journal Articles

RUNX1 represses the erythroid gene expression program during megakaryocytic differentiation

Olga N. Kuvardina, Julia Herglotz, Stephan Kolodziej, Nicole Kohrs, Stefanie Herkt, Bartosch Wojcik, Thomas Oellerich, Jasmin Corso, Kira Behrens, Ashok Kumar, Helge Hussong, Henning Urlaub, Joachim Koch, Hubert Serve, Halvard Bonig, Carol Stocking, Michael A. Rieger, Jörn Lausen
Journal: Blood
Blood (2015) 125 (23): 3570–3579.
https://doi.org/10.1182/blood-2014-11-610519
Published: 2015
Includes: Supplemental data