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Journal Articles

O-linked sialic acid residues on platelet membrane glycoprotein IIb mask the human HPA-9b alloepitope

Nanyan Zhang, Mia J. Sullivan, Brian R. Curtis, Peter J. Newman

Blood (2023) 142 (22): 1909–1917.

https://doi.org/10.1182/blood.2023021122

Published: 2023

Includes: Supplemental data

Journal Articles

Fetal Maternal Hemorrhage As a Trigger for Fetal/Neonatal Alloimmune Thrombocytopenia: Evidence from a Murine Model

Huiying Zhi, Debra K. Newman, Peter J. Newman

Blood (2023) 142 (Supplement 1): 2664.

https://doi.org/10.1182/blood-2023-178032

Published: 2023

Journal Articles

Bioengineered Glycoprotein-Deficient iPSC-Derived Megakaryocytes for the Sensitive Detection and Characterization of Patient Antibodies in Autoimmune Thrombocytopenia

Nanyan Zhang, Brian R. Curtis, Peter J. Newman

Blood (2023) 142 (Supplement 1): 700.

https://doi.org/10.1182/blood-2023-178049

Published: 2023

Journal Articles

Prophylactic administration of HPA-1a–specific antibodies prevents fetal/neonatal alloimmune thrombocytopenia in mice

Huiying Zhi, Douglas Sheridan, Debra K. Newman, Peter J. Newman

Blood (2022) 140 (20): 2146–2153.

https://doi.org/10.1182/blood.2022015666

Published: 2022

Includes: Supplemental data

Journal Articles

CD4+ T Cells Are Required for Production of Disease-Causing Antibodies in an Alloantigen-Specific Murine Model of Fetal/Neonatal Alloimmune Thrombocytopenia

Huiying Zhi, Guoping Fu, Renren Wen, Demin Wang, Peter J. Newman, Debra K. Newman

Blood (2022) 140 (Supplement 1): 2828.

https://doi.org/10.1182/blood-2022-169883

Published: 2022

Journal Articles

Prevention of Fetal/Neonatal Alloimmune Thrombocytopenia in a Preclinical Model By Monoclonal Anti-HPA-1a Antibody Prophylaxis: Structural and Functional Properties of Antibody Variant Isoforms

Trude Victoria Mørtberg, Huiying Zhi, Gestur Vidarsson, Stian Foss, Terje E Michaelsen, Bjørn Skogen, Tor Brynjar Stuge, Jan Terje Andersen, Peter J. Newman, Maria Therese Ahlen

Blood (2021) 138 (Supplement 1): 1011.

https://doi.org/10.1182/blood-2021-149196

Published: 2021

Journal Articles

Prophylactic Administration of Antibodies Specific for the HPA-1a Epitope Prevents Alloimmunization and Platelet Destruction in a Murine Model of Fetal Neonatal Alloimmune Thrombocytopenia

Huiying Zhi, Douglas Sheridan, Peter J. Newman

Blood (2021) 138 (Supplement 1): 3153.

https://doi.org/10.1182/blood-2021-148557

Published: 2021

Journal Articles

Genetic Removal of Terminal Sialic Acid Residues from the O-Linked Glycans Adjacent to the HPA-9b Polymorphism of Platelet Membrane Glycoprotein IIb Improves the Binding and Detection of HPA-9b Patient Alloantibodies

Nanyan Zhang, Brian R. Curtis, Peter J. Newman

Blood (2021) 138 (Supplement 1): 352.

https://doi.org/10.1182/blood-2021-144718

Published: 2021

Journal Articles

Conditional CRISPR-Mediated Deletion of Lyn Kinase Promotes Megakaryocyte Differentiation, Platelet Production and Function

Alyssa J. Moroi, PhD, Peter J. Newman, PhD

Blood (2020) 136 (Supplement 1): 30.

https://doi.org/10.1182/blood-2020-141066

Published: 2020

Journal Articles

Bioengineered iPSC-derived megakaryocytes for the detection of platelet-specific patient alloantibodies

Nanyan Zhang, Sentot Santoso, Richard H. Aster, Brian R. Curtis, Peter J. Newman

Blood (2019) 134 (22): e1–e8.

https://doi.org/10.1182/blood.2019002225

Published: 2019

Includes: Supplemental data

Journal Articles

An Authentic Murine Model of Fetal/Neonatal Alloimmune Thrombocytopenia

Huiying Zhi, PhD, Maria Therese Ahlen, PhD, Trude Rasmussen, Bjørn Skogen, MD, Peter J. Newman, PhD

Blood (2019) 134 (Supplement_1): 97.

https://doi.org/10.1182/blood-2019-130573

Published: 2019

Journal Articles

Structural basis for PECAM-1 homophilic binding

Cathy Paddock, Dongwen Zhou, Panida Lertkiatmongkol, Peter J. Newman, Jieqing Zhu

Blood (2016) 127 (8): 1052–1061.

https://doi.org/10.1182/blood-2015-07-660092

Published: 2016

Includes: Supplemental data

Journal Articles

CRISPR/Cas9-mediated conversion of human platelet alloantigen allotypes

Nanyan Zhang, Huiying Zhi, Brian R. Curtis, Sridhar Rao, Chintan Jobaliya, Mortimer Poncz, Deborah L. French, Peter J. Newman

Blood (2016) 127 (6): 675–680.

https://doi.org/10.1182/blood-2015-10-675751

Published: 2016

Includes: Supplemental data

Journal Articles

Structural Basis for PECAM-1 Homophilic Binding

Cathy Paddock, Dongwen Zhou, PhD, Panida Lertkiatmongkol, Peter J. Newman, PhD, Jieqing Zhu, PhD

Blood (2015) 126 (23): 1041.

https://doi.org/10.1182/blood.V126.23.1041.1041

Published: 2015

Journal Articles

Quantitative Measurement of VWF Binding to the Platelet Integrin αIIbβ3 - Abnormalities Identified in Individuals with VWD

Robert R. Montgomery, MD, Veronica H Flood, MD, Jieqing Zhu, PhD, Pamela A Christopherson, Peter J. Newman, PhD, Daniel W. Bougie, PhD, Patti Morateck

Blood (2015) 126 (23): 1107.

https://doi.org/10.1182/blood.V126.23.1107.1107

Published: 2015

Journal Articles

Involvement of the EGF Domain in the Formation of the Human Platelet Alloantigen, HPA-1a

Huiying Zhi, MD PhD, Panida Lertkiatmongkol, Brian R Curtis, PhD D(ABMLI), Peter J. Newman, PhD

Blood (2015) 126 (23): 2340.

https://doi.org/10.1182/blood.V126.23.2340.2340

Published: 2015

Journal Articles

Crispr/Cas9-Mediated Generation of Mouse Platelets Expressing the Human Platelet Alloantigen, HPA-1a

Huiying Zhi, MD PhD, Nanyan Zhang, MD PhD, Jamie Foeckler, Shawn Kalloway, PhD, Sridhar Rao, MD PhD, Brian R Curtis, PhD D(ABMLI), Hartmut Weiler, PhD, Peter J. Newman, PhD

Blood (2015) 126 (23): 2341.

https://doi.org/10.1182/blood.V126.23.2341.2341

Published: 2015

Journal Articles

Species-Specific Roles for a2,3- and a2,6-Linked Sialic Acid Residues in PECAM-1-Mediated Homophilic Interactions

Panida Lertkiatmongkol, MSc, Cathy Paddock, Peter J. Newman, PhD

Blood (2015) 126 (23): 3450.

https://doi.org/10.1182/blood.V126.23.3450.3450

Published: 2015

Journal Articles

Integrin αIIbβ3-Mediated Outside-in Signaling: Brake or Amplifier of Platelet Activation?

Baiyun Dai, Predoctor, Peng Wu, Predoctor, Feng Xue, Predoctor, Renchi Yang, MD, Ziqiang Yu, MD, Kesheng Dai, Changgeng Ruan, Jieqing Zhu, PhD, Peter J. Newman, PhD, Cunji Gao, MD PhD

Blood (2014) 124 (21): 4161.

https://doi.org/10.1182/blood.V124.21.4161.4161

Published: 2014

Journal Articles

Designer Platelets: Crispr/Cas-Mediated Conversion of Human Platelet Alloantigen Allotypes

Nanyan Zhang, MD PhD, Huiying Zhi, MD PhD, Sridhar Rao, Peter J. Newman, PhD

Blood (2014) 124 (21): 573.

https://doi.org/10.1182/blood.V124.21.573.573

Published: 2014

NARROW

O-linked sialic acid residues on platelet membrane glycoprotein IIb mask the human HPA-9b alloepitope

Fetal Maternal Hemorrhage As a Trigger for Fetal/Neonatal Alloimmune Thrombocytopenia: Evidence from a Murine Model

Bioengineered Glycoprotein-Deficient iPSC-Derived Megakaryocytes for the Sensitive Detection and Characterization of Patient Antibodies in Autoimmune Thrombocytopenia

Prophylactic administration of HPA-1a–specific antibodies prevents fetal/neonatal alloimmune thrombocytopenia in mice

CD4+ T Cells Are Required for Production of Disease-Causing Antibodies in an Alloantigen-Specific Murine Model of Fetal/Neonatal Alloimmune Thrombocytopenia

Prevention of Fetal/Neonatal Alloimmune Thrombocytopenia in a Preclinical Model By Monoclonal Anti-HPA-1a Antibody Prophylaxis: Structural and Functional Properties of Antibody Variant Isoforms

Prophylactic Administration of Antibodies Specific for the HPA-1a Epitope Prevents Alloimmunization and Platelet Destruction in a Murine Model of Fetal Neonatal Alloimmune Thrombocytopenia

Genetic Removal of Terminal Sialic Acid Residues from the O-Linked Glycans Adjacent to the HPA-9b Polymorphism of Platelet Membrane Glycoprotein IIb Improves the Binding and Detection of HPA-9b Patient Alloantibodies

Conditional CRISPR-Mediated Deletion of Lyn Kinase Promotes Megakaryocyte Differentiation, Platelet Production and Function

Bioengineered iPSC-derived megakaryocytes for the detection of platelet-specific patient alloantibodies

An Authentic Murine Model of Fetal/Neonatal Alloimmune Thrombocytopenia

Structural basis for PECAM-1 homophilic binding

CRISPR/Cas9-mediated conversion of human platelet alloantigen allotypes

Structural Basis for PECAM-1 Homophilic Binding

Quantitative Measurement of VWF Binding to the Platelet Integrin αIIbβ3 - Abnormalities Identified in Individuals with VWD

Involvement of the EGF Domain in the Formation of the Human Platelet Alloantigen, HPA-1a

Crispr/Cas9-Mediated Generation of Mouse Platelets Expressing the Human Platelet Alloantigen, HPA-1a

Species-Specific Roles for a2,3- and a2,6-Linked Sialic Acid Residues in PECAM-1-Mediated Homophilic Interactions

Integrin αIIbβ3-Mediated Outside-in Signaling: Brake or Amplifier of Platelet Activation?

Designer Platelets: Crispr/Cas-Mediated Conversion of Human Platelet Alloantigen Allotypes

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American Society of Hematology

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American Society of Hematology

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