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Robert F. Wynn
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Journal Articles

Outcomes of hematopoietic stem cell transplantation in 813 pediatric patients with Fanconi anemia

CME Clinical Trials & Observations
Su Han Lum, Dirk-Jan Eikema, Brian Piepenbroek, Robert F. Wynn, Sujith Samarasinghe, Arnaud Dalissier, Krysztof Kalwak, Mouhab Ayas, Rose-Marie Hamladji, Akif Yesilipek, Jean-Hugues Dalle, Duygu Uckan-Cetinkaya, Marc Bierings, Alphan Kupesiz, Khalid Halahleh, Elena Skorobogatova, Gülyüz Öztürk, Maura Faraci, Cecile Renard, Pamela Evans, Selim Corbacioglu, Franco Locatelli, Carlo Dufour, Antonio Risitano, Régis Peffault de Latour
Journal: Blood
Blood (2024) 144 (12): 1329–1342.
https://doi.org/10.1182/blood.2023022751
Published: 2024
Includes: Supplemental data
Journal Articles

Alternative donor transplantation for severe aplastic anemia: a comparative study of the SAAWP EBMT

CME Clinical Trials & Observations
Juan Montoro, Dirk-Jan Eikema, Joe Tuffnell, Victoria Potter, Krzysztof Kalwak, Constantijn J. M. Halkes, Alexander Kulagin, Matthew Collin, Robert F. Wynn, Stephen Robinson, Emma Nicholson, Henrik Sengeloev, Jennifer Clay, Khalid Halahleh, Elena Skorobogatova, Jaime Sanz, Jakob Passweg, Stephan Mielke, Samppa Ryhänen, Ben Carpenter, Tobias Gedde-Dahl, Eleni Tholouli, Renato Fanin, Philippe Lewalle, Austin Kulasekararaj, Antonio Risitano, Régis Peffault de Latour
Journal: Blood
Blood (2024) 144 (3): 323–333.
https://doi.org/10.1182/blood.2024024173
Published: 2024
Journal Articles

Preliminary Results of a Phase 2a Clinical Trial to Evaluate Safety, Tolerability and Antiviral Activity of Intravenous Brincidofovir (BCV IV) in Immunocompromised Patients with Adenovirus Infection

Michael Grimley, Gabriela Maron, Carlos A Gomez, Vinod K. Prasad, Jasmeen Dara, Genovefa A Papanicolaou, Koji Fukushima, Robert F. Wynn, Michael Boeckh
Journal: Blood
Blood (2023) 142 (Supplement 1): 112.
https://doi.org/10.1182/blood-2023-179901
Published: 2023
Journal Articles

Graft-Versus-Host Disease after Anti-CD19 Chimeric Antigen Receptor T-Cell Infusion Post Allogeneic Hematopoietic Cell Transplantation: A Transplant Complications and Paediatric Disease Working Parties EBMT Joint Study

Guillermo Orti, Christophe Peczynski, Christian Koenecke, William Boreland, Maeve O'Reilly, Martin Bornhäuser, Adriana Balduzzi, Caroline Besley, Krzysztof Kalwak, Samppa Ryhanen, Sr., Tayfun Güngör, Robert F. Wynn, Peter Bader, Stephan Mielke, Didier Blaise, Persis Amrolia, Ibrahim Yakoub-Agha, Friso G. J. Calkoen, Maria-Luisa Schubert, Victoria Potter, Wolfgang Holter, Nicolaus Kröger, Mi Kwon, Henrik Sengeloev, Helene Schoemans, Ivan Sergeevich Moiseev, Olaf Penack, Zinaida Peric
Journal: Blood
Blood (2023) 142 (Supplement 1): 2189.
https://doi.org/10.1182/blood-2023-177715
Published: 2023
Journal Articles

Biochemical Engraftment and Clinical Outcomes Following Ex-Vivo Autologous Stem Cell Gene Therapy for Mucopolysaccharidosis Type IIIA

Robert F Wynn, Jane L Kinsella, Rebecca J Holley, Jane Potter, Adrian J. Thrasher, Claire Booth, Karen Buckland, Natalia Izotova, Stewart Rust, Daniel Weisberg, Heather J Church, Karen L Tylee, Kathryn L Brammeier, Helena Lee, Laura Ford, Atusa Sadegholnejat, Simon A Jones, Stuart Ellison, Brian Bigger
Journal: Blood
Blood (2022) 140 (Supplement 1): 1897–1898.
https://doi.org/10.1182/blood-2022-168672
Published: 2022
Journal Articles

Specific Cytogenetic Abnormalities at Diagnosis Predict Survival after Hematopoietic Cell Transplant in Poor-Risk Pediatric Acute Myeloid Leukemia: A PDWP/EBMT Study

Akshay Sharma, Jacques-Emmanuel Galimard, Angharad Pryce, Senthil Bhoopalan, Arnaud Dalissier, Jean-Hugues Dalle, Franco Locatelli, Charlotte Jubert, Oana Mirci-Danicar, Vassiliki Kitra-Roussou, Yves Bertrand, Franca Fagioli, Fanny Rialland, Alessandra Biffi, Robert F Wynn, Gerard Michel, Francesco Paolo P Tambaro, Ali Abdallah Ahmari, Abdelghani Tbakhi, Caroline Furness, Miguel Ángel Díaz Pérez, Petr Sedlacek, Ivana Bodova, Maura Faraci, Kanchan Rao, Marie Thérèse Rubio, Brenda Gibson, Neel S. Bhatt, Selim Corbacioglu
Journal: Blood
Blood (2022) 140 (Supplement 1): 1882–1884.
https://doi.org/10.1182/blood-2022-162596
Published: 2022
Journal Articles

T-Cell Replete Unrelated Cord Blood Transplant Give Superior Outcomes to Other Donor Sources in High Risk and Relapsed/Refractory Paediatric Myeloid Malignancy

Claire Horgan, Khushnuma Mullanfiroze, Archana Rauthan, Katharine Patrick, Naeem Akram Butt, Oana Mirci-Danicar, Olya O'Connor, Caroline Furness, Akshay Deshpande, Sarah Lawson, Valerie Broderick, Pamela Evans, Brenda Gibson, Wing Roberts, Sevasti Galani, Amy A. Kirkwood, Beki James, Kanchan Rao, Persis J. Amrolia, Robert F. Wynn
Journal: Blood
Blood (2022) 140 (Supplement 1): 4889–4891.
https://doi.org/10.1182/blood-2022-165327
Published: 2022
Journal Articles

Outcome of Haematopoietic Cell Transplantation in 813 Children with Fanconi Anaemia: A Study on Behalf of the EBMT Severe Aplastic Anaemia Working Party and Paediatric Disease Working Party

Su Han Lum, Sujith Samarasinghe, Dirk-Jan Eikema, Brian Piepenbroek, Arnaud Dalissier, Mouhab Ayas, Ashrafsadat Mousavi, Rose-Marie Hamladji, Akif Yesilipek, Jean-Hugues Dalle, Savas Kansoy, Franco Locatelli, Duygu Çetinkaya, Marc Bierings, O. Alphan Kupesiz, Abdelghani Tbakhi, Elena Skorobogatova, Gülyüz Öztürk, Maura Faraci, Yves Bertrand, Pamela Evans, Selim Carbacioglu, Carlo Dufour, Antonio Risitano, Robert F Wynn, Régis Peffault de Latour
Journal: Blood
Blood (2022) 140 (Supplement 1): 657–659.
https://doi.org/10.1182/blood-2022-163140
Published: 2022
Journal Articles

Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation for Congenital Amegakaryocytic Thrombocytopenia, a PDWP/EBMT Study

Clemence Aldebert, Mony Fahd, Jacques-Emmanuel Galimard, Ibrahim A. Ghemlas, Marco Zecca, Juliana Silva, Alexander Mohseny, Alphan Kupesiz, Rose-Marie Hamladji, Nuno Miranda, Tayfun Gungor, Robert F Wynn, Pietro Merli, Mikael Sundin, Maura Faraci, Cristina Díaz-de-Heredia, Birgit Burkhardt, Victoria Bordon, Charlotte Jubert, Peter Bader, Marianne Ifversen, Concepcion Herrera Arroyo, Natalia Maximova, Susana Riesco, Jerry Stein, Arnaud Dalissier, Franco Locatelli, Krzysztof Kalwak, Jean-Hugues Dalle, Selim Corbacioglu
Journal: Blood
Blood (2022) 140 (Supplement 1): 10895–10896.
https://doi.org/10.1182/blood-2022-166636
Published: 2022
Journal Articles

Systematic Intention to Treat Analysis of Real-World Outcomes in Children and Young Adults Receiving Tisagenlecleucel: From Elegibility through Treatment Failure

Macarena Oporto Espuelas, Saskia Burridge, Denise Bonney, Kelly Watts, Claire Roddie, Maeve A O'Reilly, Geoff Shenton, John A Snowden, Caroline Furness, Katarzyna Aleksandra Aleksandra Jalowiec, Lorna Neill, Katherine Clesham, Emma Nicholson, Anna Castleton, Amit Patel, Caroline Besley, Robert F Wynn, Ajay Vora, David I. Marks, Lindsay George, Ben Uttenthal, Sridhar Chaganti, Michelle Cummins, Persis J Amrolia, Rachael E Hough, Sara Ghorashian
Journal: Blood
Blood (2022) 140 (Supplement 1): 2408–2410.
https://doi.org/10.1182/blood-2022-162863
Published: 2022
Journal Articles

Dual Antigen Targeting with Co-Transduced CD19/22 CAR T Cells May Prevent Antigen-Negative Relapse after CAR T Cell Therapy for Relapsed/Refractory ALL

Sara Ghorashian, Giovanna Lucchini, Rachel Richardson, Kyvi Nguyen, Craig Terris, Macarena Oporto-Espuelas, Jenny Yeung, Danielle Pinner, Jan Chu, Lindsey Williams, Ka-yuk Ko, Chloe Walding, Kelly Watts, Sarah Inglott, Stuart Adams, Emma Gravett, Kimberly Gilmour, Alka Lal, Sangeetha Kunaseelan, Bilyana Popova, Andre Lopes, Yenting Ngai, Evangelia K Kokalaki, Milena Balasch Carulla, Khushnuma Mullanfiroze, Arina Lazareva, Vesna Pavasovic, Anupama Rao, Jack Bartram, Ajay Vora, Robert Chiesa, Juliana Silva, Kanchan Rao, Katherine Clesham, Denise Bonney, Robert F Wynn, Martin Pule, Rachael E Hough, Persis J Amrolia
Journal: Blood
Blood (2022) 140 (Supplement 1): 10352–10354.
https://doi.org/10.1182/blood-2022-164879
Published: 2022
Journal Articles

COVID-19 Infection of HSCT Recipients Is Associated with High Mortality but No Detectable Cytokine Storm at Presentation

Giovanna Lucchini, Elena Cozma, Aimee Jackson, Kimberly Gilmour, Rachel Elizabeth Protheroe, Eleni Tholouli, Robert F Wynn, Keith Wilson, Karl S Peggs, Victoria Potter, Anne Parker, Charles Craddock, Shankara Paneesha, Emma Nicholson, David I. Marks, Oana Mirci-Danicar, Christopher Parrish, Alexander M Martin, Graham McIlroy, Rebecca Bishop, Rebecca Collings, Ellie Williams, Persis J Amrolia
Journal: Blood
Blood (2021) 138 (Supplement 1): 1788.
https://doi.org/10.1182/blood-2021-146515
Published: 2021
Journal Articles

Transplantation for Congenital Sideroblastic Anaemia Is Feasible and Offers Outcomes Comparable to Other Transfusion Dependent Anaemias. a Joint Retrospective Study of the Paediatric Diseases and Severe Aplastic Anaemia Working Parties (PDWP/SAAWP) of EBMT

Josu de la Fuente, Dirk-Jan Eikema, Paul Bosman, Robert F Wynn, MRCP,MDFRCPath, Miguel Díaz, Peter J Shaw, MD, Amal Al-Seraihy, MD, Muhlis Cem Ar, MD PhD, Mohamed Salaheldin Mohamed, Dominique Bron, MDPhD, Cristina Díaz de Heredia, MD PhD, Tobias Gedde-Dahl, Brenda Gibson, MD PhD, Rupert Handgretinger, MD, Professor John G. Gribben, MD DSc, Tessa Kerre, MD, Vassiliki Kitra-Roussou, MD, Stig Lenhoff, Jose Maria Moraleda, MD PhD, Antonio Perez Martinez, MD PhD, John Moppett, FRCPath, Henrik Sengeloev, Abdelghani Tbakhi, MD, Hendrik Veelken, MD PhD, Estelle Verburgh, MBChB, M MDInt, FCPSA, PhD, Giuseppe Visani, Antonio Risitano, Carlo Dufour, Selim Corbacioglu, MD, Regis Peffault De Latour, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 45–47.
https://doi.org/10.1182/blood-2020-142397
Published: 2020
Journal Articles

Ex-Vivo Autologous Stem Cell Gene Therapy Clinical Trial for Mucopolysaccharidosis Type IIIA: Trial in Progress - NCT04201405

Jane L Kinsella, MBChB, Robert F Wynn, MRCP,MDFRCPath, Brian Bigger, PhD, Adrian J. Thrasher, MBBS, PhD FMedSci, Claire Booth, MBBS, PhD MSc, Karen Buckland, PhD, Natalia Izotova, Stewart Rust, B.Sc. (Hons), D.Clin.Psych, Pg.Dip., C.Psychol., AfBPS., Daniel Weisberg, BSc, PhD PGCert, ClinPsyD, Heather J Church, PhD, Kathryn L Brammeier, Karen L Tylee, Ceri Jones, BSc, Helena Lee, Laura Ford, Atusa Sadegholnejat, Stuart Ellison, Simon A Jones, MBChB, BSc, MRCPCH
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–16.
https://doi.org/10.1182/blood-2020-141762
Published: 2020
Journal Articles

Long-term outcome of Hurler syndrome patients after hematopoietic cell transplantation: an international multicenter study

Mieke Aldenhoven, Robert F. Wynn, Paul J. Orchard, Anne O’Meara, Paul Veys, Alain Fischer, Vassili Valayannopoulos, Benedicte Neven, Attilio Rovelli, Vinod K. Prasad, Jakub Tolar, Heather Allewelt, Simon A. Jones, Rossella Parini, Marleen Renard, Victoria Bordon, Nico M. Wulffraat, Tom J. de Koning, Elsa G. Shapiro, Joanne Kurtzberg, Jaap Jan Boelens
Journal: Blood
Blood (2015) 125 (13): 2164–2172.
https://doi.org/10.1182/blood-2014-11-608075
Published: 2015
Includes: Supplemental data
Journal Articles

Mutations in TRNT1 cause congenital sideroblastic anemia with immunodeficiency, fevers, and developmental delay (SIFD)

Brief Report
Pranesh K. Chakraborty, Klaus Schmitz-Abe, Erin K. Kennedy, Hapsatou Mamady, Turaya Naas, Danielle Durie, Dean R. Campagna, Ashley Lau, Anoop K. Sendamarai, Daniel H. Wiseman, Alison May, Stephen Jolles, Philip Connor, Colin Powell, Matthew M. Heeney, Patricia-Jane Giardina, Robert J. Klaassen, Caroline Kannengiesser, Isabelle Thuret, Alexis A. Thompson, Laura Marques, Stephen Hughes, Denise K. Bonney, Sylvia S. Bottomley, Robert F. Wynn, Ronald M. Laxer, Caterina P. Minniti, John Moppett, Victoria Bordon, Michael Geraghty, Paul B. M. Joyce, Kyriacos Markianos, Adam D. Rudner, Martin Holcik, Mark D. Fleming
Journal: Blood
Blood (2014) 124 (18): 2867–2871.
https://doi.org/10.1182/blood-2014-08-591370
Published: 2014
Includes: Supplemental data
Journal Articles

A novel syndrome of congenital sideroblastic anemia, B-cell immunodeficiency, periodic fevers, and developmental delay (SIFD)

Daniel H. Wiseman, Alison May, Stephen Jolles, Philip Connor, Colin Powell, Matthew M. Heeney, Patricia J. Giardina, Robert J. Klaassen, Pranesh Chakraborty, Michael T. Geraghty, Nathalie Major-Cook, Caroline Kannengiesser, Isabelle Thuret, Alexis A. Thompson, Laura Marques, Stephen Hughes, Denise K. Bonney, Sylvia S. Bottomley, Mark D. Fleming, Robert F. Wynn
Journal: Blood
Blood (2013) 122 (1): 112–123.
https://doi.org/10.1182/blood-2012-08-439083
Published: 2013
Includes: Supplemental data
Journal Articles

Impact of immune modulation with in vivo T-cell depletion and myleoablative total body irradiation conditioning on outcomes after unrelated donor transplantation for childhood acute lymphoblastic leukemia

Clinical Trials & Observations
Paul Veys, Robert F. Wynn, Kwang Woo Ahn, Sujith Samarasinghe, Wensheng He, Denise Bonney, John Craddock, Jacqueline Cornish, Stella M. Davies, Christopher C. Dvorak, Reggie E. Duerst, Thomas G. Gross, Neena Kapoor, Carrie Kitko, Robert A. Krance, Wing Leung, Victor A. Lewis, Colin Steward, John E. Wagner, Paul A. Carpenter, Mary Eapen
Journal: Blood
Blood (2012) 119 (25): 6155–6161.
https://doi.org/10.1182/blood-2012-01-405795
Published: 2012
Journal Articles

Success of Adoptive Immunotherapy Followed by Stem Cell Transplantation in the Management of Epstein Barr Virus (EBV)-Driven Primary Central Nervous System Lymphoma (PCNSL) in Immunodeficient Child.

Maged I. Gharib, MD, MRCP, MRCPath, Tanzina Haque, MB.BS, PhD, MRCPath, James A. Nicholson, MB.BS, MRCP, Gwen Wilkie, BSc., Marie Morton-Jones, BSc, Trevor F. Carr, PhD, Peter D. Arkwright, MB, D. Phil, Andrew J.L. Turner, MB.ChB, FRCPath, Anna M. Kelsey, FRCPath, Dorothy H. Crawford, MD, PhD, DSc, Robert F. Wynn, MD, MRCP, MRCPath
Journal: Blood
Blood (2004) 104 (11): 3115.
https://doi.org/10.1182/blood.V104.11.3115.3115
Published: 2004
Journal Articles

The Impact of Monitoring Epstein Barr Virus PCR in Paediatric Bone Marrow Transplant Patients: Can It Successfully Predict Outcome and Guide Intervention.

Hayley M. Greenfield, MRCP, Maged I. Gharib, MRCP, Andrew J.L. Turner, MRCPath, Mary L. Coussons, Andrew M. Will, MRCP, Ruth F. Jarrett, FRCPath, Mario P. Macheta, MRCP, Robert F. Wynn, MRCP
Journal: Blood
Blood (2004) 104 (11): 5064.
https://doi.org/10.1182/blood.V104.11.5064.5064
Published: 2004