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Journal Articles

BRUIN CLL-322: A Phase 3 Open-Label, Randomized Study of Fixed Duration Pirtobrutinib Plus Venetoclax and Rituximab Versus Venetoclax and Rituximab in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (Trial in Progress)

Anthony R. Mato, William G. Wierda, John M. Pagel, Matthew S. Davids, Pier Luigi Zinzani, Yi Lu, Hui Liu, Safi Shahda, Ching Ching Leow, Constantine S. Tam, Jennifer A. Woyach, Toby A. Eyre

Blood (2021) 138 (Supplement 1): 3742.

https://doi.org/10.1182/blood-2021-145936

Published: 2021

Journal Articles

RNA Sequencing in Childhood B-Lymphoblastic Leukemia Improves Molecular and Risk Assignment

Allen Eng Juh Yeoh, MD, Zhenhua Li, PhD, Shawn Lee, MD, Winnie Hui Ni Chin, Nan Jiang, PhD, Yi Lu, PhD, Shirley Kow Yin Kham, BSc, Ah Moy Tan, MD, Hai_peng Lin, Thuan Chong Quah, Hany Ariffin, Jun J. Yang, PhD

Blood (2019) 134 (Supplement_1): 651.

https://doi.org/10.1182/blood-2019-131653

Published: 2019

Journal Articles

Efficacy and Survival in Newly Diagnosed Advanced Extranodal Natural Killer/T-Cell Lymphoma: A Randomized, Controlled, Multicenter and Open-Labled Study with Ddgp Regimen Versus SMILE Regimen

Blood (2019) 134 (Supplement_1): 463.

https://doi.org/10.1182/blood-2019-127811

Published: 2019

Journal Articles

Intensifying Treatment in Childhood B-Lymphoblastic Leukemia with IKZF1 Deletions Negates Its Adverse Outcome: Results of Ma-Spore ALL 2003 and 2010 Studies

Yi Lu, PhD, Winnie Hui Ni Chin, Evelyn Huizi Lim, Shirley Kow Yin Kham, BSc, Ah Moy Tan, MD, Hany Ariffin, MD PhD, Allen Eng Juh Yeoh, MD

Blood (2017) 130 (Supplement 1): 478.

https://doi.org/10.1182/blood.V130.Suppl_1.478.478

Published: 2017

Journal Articles

Dehydropeptidase 1 Promoted Survival and Cell Cycle Progression through Regulation of CREB and P53 Pathways in B-Cell ALL

Jia-Min Zhang, MD, Shu-Juan Wang, Wen-Yi Lu, MD, Jiao Zhou, MD, Jing Zhang, MD, Xiao-Jun Huang, MD, Kai-Yan Liu, Guorui Ruan

Blood (2017) 130 (Supplement 1): 2719.

https://doi.org/10.1182/blood.V130.Suppl_1.2719.2719

Published: 2017

Journal Articles

Overexpression of Cysteine and Glycine-Rich Protein 2 in Bone Marrow As a Novel Biomarker in Adult B-Cell Acute Lymphoblastic Leukemia

Shu-Juan Wang, Wei-Min Wang, Wen-Yi Lu, Ya-Zhen Qin, Yue-Yun Lai, Yan-Rong Liu, Xiao-Jun Huang, Kai-Yan Liu, Guo-Rui Ruan

Blood (2016) 128 (22): 5271.

https://doi.org/10.1182/blood.V128.22.5271.5271

Published: 2016

Journal Articles

Abnormal Expression of the Chemokine (C-C Motif) Ligand 17 Gene in Adult B-Cell Acute Lymphoblastic Leukemia

Yong-Huai Feng, Wei-Min Wang, Wen-Yi Lu, Shu-Juan Wang, Qiu-Mei Yao, Jiao Zhou, Jia-Min Zhang, Xiao-Jun Huan, Kai-Yan Liu, Guo-Rui Ruan

Blood (2016) 128 (22): 5157.

https://doi.org/10.1182/blood.V128.22.5157.5157

Published: 2016

Journal Articles

Whole Transcriptome Sequencing Identified a Distinct Subtype of Acute Lymphoblastic Leukemia with Abnormalities of CREBBP and EP300

Blood (2016) 128 (22): 3912.

https://doi.org/10.1182/blood.V128.22.3912.3912

Published: 2016

Journal Articles

Effective Response Metric (ERM-D8) Using Time-Series Gene Expression Profiling at Diagnosis and Day 8 of Remission-Induction Therapy Is a Novel Early Prognostic Marker to Predict Relapse in Childhood Acute Lymphoblastic Leukemia (ALL) — a Malaysia-Singapore ALL Study

Allen Eng Juh Yeoh, MD, Zhenhua Li, PhD, Difeng Dong, PhD, Yi Lu, PhD, Jan Trka, MD, PhD, Prof., Shirley Kow Yin Kham, B.Sc., Ah Moy Tan, MD, Hany Ariffin, MD, Limsoon Wong, PhD

Blood (2014) 124 (21): 2393.

https://doi.org/10.1182/blood.V124.21.2393.2393

Published: 2014

Journal Articles

Genomic Profiling of Pharmacogenetic Variants Establishes a SNP-Based Predictor for Poor Outcome in Asian Children with Acute Lymphoblastic Leukemia (ALL): A Report from Malaysia-Singapore ALL Study Group

Yi Lu, PhD, Marc Hai Liang Wong, M.B.,B.S., Zhenhua Li, PhD, Shirley Kow Yin Kham, B.Sc., Ah Moy Tan, MD, Hany Ariffin, MD, Allen Eng Juh Yeoh, MD

Blood (2014) 124 (21): 1069.

https://doi.org/10.1182/blood.V124.21.1069.1069

Published: 2014

Journal Articles

Vincristine and Prednisolone Combination Reduces MDR1 and Microenvironment-Mediated Treatment Resistance In Acute Lymphoblastic Leukemia

Nan Jiang, Ph.D., Zhenhua Li, Ph.D., Grace Shimin Koh, B.Sc., Yi Lu, Ph.D., Shirley K.Y. Kham, Allen Eng Juh Yeoh, MD

Blood (2013) 122 (21): 2529.

https://doi.org/10.1182/blood.V122.21.2529.2529

Published: 2013

Journal Articles

Host Pharmacogenetic Factors Significantly Contribute to Refinement of Prognosis in Children with Acute Lymphoblastic Leukemia (ALL): Result From the Malaysia-Singapore (Ma-Spore) ALL 2003 Study

Yi Lu, Ph.D., Shirley Kow Yin Kham, B.Sc., Arrifin Hany, M.D., Ah Moy Tan, M.D., Thuan Chong Quah, M.D., Allen Eng Juh Yeoh, M.D.

Blood (2011) 118 (21): 567.

https://doi.org/10.1182/blood.V118.21.567.567

Published: 2011

Journal Articles

Integrated Molecular and Pharmacogenetic Profiles in Prediction of Early Response to Therapy in Children with Acute Lymphoblastic Leukemia (ALL): A Report From Malaysia-Singapore ALL Study Group.

Yi Lu, Ph.D., Shirley Kow Yin Kham, B.Sc., Hany Ariffin, M.D., Ah Moy Tan, M.D., Hai Peng Lin, M.D., Thuan Chong Quah, M.D., Allen Eng Juh Yeoh, M.D.

Blood (2009) 114 (22): 2624.

https://doi.org/10.1182/blood.V114.22.2624.2624

Published: 2009

Journal Articles

The Research of Phenylhexyl Isothiocyanate’s Influence on p16 Gene Methylation of Leukaemia Cell

Blood (2008) 112 (11): 4497.

https://doi.org/10.1182/blood.V112.11.4497.4497

Published: 2008

Journal Articles

BIM Regulates Prednisolone-Induced Apoptosis in B-Lineage ALL: A Potential Biomarker.

Nan Jiang, PhD, Grace Shi Min Koh, BSc, Shirley Kow Yin Kham, BSc, Yi Lu, PhD, Fook Tim Chew, PhD, Allen Eng Juh Yeoh, MD

Blood (2008) 112 (11): 1505.

https://doi.org/10.1182/blood.V112.11.1505.1505

Published: 2008

Journal Articles

The Effect of Phenylhexyl Isothiocyanate on Drug Resistance of K562/A02 Cell Line

Bao-An Chen, MD, PhD, Peng Yuan, Jian Cheng, Feng Gao, Jia-Hua Ding, Chong Gao, Yun-Yu Sun, Jun Wang, Gang Zhao, Hui-hui Song, Wen Bao, Ze-ye Shao, Guo-hua Xia, Quan-yi Lu, Xu-dong Ma, De-long Liu, Jue-qiong Wang, Xiao-ping Pei, Ning-na Chen

Blood (2008) 112 (11): 5061.

https://doi.org/10.1182/blood.V112.11.5061.5061

Published: 2008

Journal Articles

Expression of Hypoxia-Inducible Factor (HIF) Is An Independent Favorable Prognostic Factor in Diffuse Large B-Cell Lymphoma (DLBCL) Treated with R-CHOP

Andrew M. Evens, DO, MS, Laurie H. Sehn, MD, MPH, Pedro Farinha, MD, Paul T Schumacker, PhD, Adekunle Raji, MS, Yi Lu, MD, Beverly P. Nelson, MD, Randy D. Gascoyne, MD, Leo I. Gordon, MD

Blood (2008) 112 (11): 479.

https://doi.org/10.1182/blood.V112.11.479.479

Published: 2008

Journal Articles

Gene Expression Profiling of Paired Pre- and Post-Prednisolone (PRED) BM Samples from Childhood ALL Identifies Robust Signatures for PRED Response and Eventual Outcome.

Yi Lu, Huiqing Liu, Ying Xu, Pei Lin Koh, Ariffin Hany, Limsoon Wong, Allen Eng Juh Yeoh

Blood (2006) 108 (11): 222.

https://doi.org/10.1182/blood.V108.11.222.222

Published: 2006

Journal Articles

Genetic Polymorphisms in the Folate Pathway and Risk of Childhood Acute Lymphoblastic Leukemia (ALL): MTHFR, MTHFD1, RFC1 and TS.

Allen Eng-Juh Yeoh, MD, Shirley Kow-Yin Kham, BSc, Yi Lu, PhD, Toon-Chai Foo, BSc, Hany Ariffin, MD, Thuan-Chong Quah, MD

Blood (2006) 108 (11): 2274.

https://doi.org/10.1182/blood.V108.11.2274.2274

Published: 2006

Journal Articles

A New Genotyping Chip for Childhood ALL: Using a Novel Multiplex Allele-Specific Primer Extension Strategy To Detect Twelve Polymorphisms in Six Genes Encoding for Drug-Metabolizing Enzymes.

Yi Lu, Kow-Yin Kham, Eng-Juh Yeoh

Blood (2004) 104 (11): 4500.

https://doi.org/10.1182/blood.V104.11.4500.4500

Published: 2004

NARROW

BRUIN CLL-322: A Phase 3 Open-Label, Randomized Study of Fixed Duration Pirtobrutinib Plus Venetoclax and Rituximab Versus Venetoclax and Rituximab in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (Trial in Progress)

RNA Sequencing in Childhood B-Lymphoblastic Leukemia Improves Molecular and Risk Assignment

Efficacy and Survival in Newly Diagnosed Advanced Extranodal Natural Killer/T-Cell Lymphoma: A Randomized, Controlled, Multicenter and Open-Labled Study with Ddgp Regimen Versus SMILE Regimen

Intensifying Treatment in Childhood B-Lymphoblastic Leukemia with IKZF1 Deletions Negates Its Adverse Outcome: Results of Ma-Spore ALL 2003 and 2010 Studies

Dehydropeptidase 1 Promoted Survival and Cell Cycle Progression through Regulation of CREB and P53 Pathways in B-Cell ALL

Overexpression of Cysteine and Glycine-Rich Protein 2 in Bone Marrow As a Novel Biomarker in Adult B-Cell Acute Lymphoblastic Leukemia

Abnormal Expression of the Chemokine (C-C Motif) Ligand 17 Gene in Adult B-Cell Acute Lymphoblastic Leukemia

Whole Transcriptome Sequencing Identified a Distinct Subtype of Acute Lymphoblastic Leukemia with Abnormalities of CREBBP and EP300

Effective Response Metric (ERM-D8) Using Time-Series Gene Expression Profiling at Diagnosis and Day 8 of Remission-Induction Therapy Is a Novel Early Prognostic Marker to Predict Relapse in Childhood Acute Lymphoblastic Leukemia (ALL) — a Malaysia-Singapore ALL Study

Genomic Profiling of Pharmacogenetic Variants Establishes a SNP-Based Predictor for Poor Outcome in Asian Children with Acute Lymphoblastic Leukemia (ALL): A Report from Malaysia-Singapore ALL Study Group

Vincristine and Prednisolone Combination Reduces MDR1 and Microenvironment-Mediated Treatment Resistance In Acute Lymphoblastic Leukemia

Host Pharmacogenetic Factors Significantly Contribute to Refinement of Prognosis in Children with Acute Lymphoblastic Leukemia (ALL): Result From the Malaysia-Singapore (Ma-Spore) ALL 2003 Study

Integrated Molecular and Pharmacogenetic Profiles in Prediction of Early Response to Therapy in Children with Acute Lymphoblastic Leukemia (ALL): A Report From Malaysia-Singapore ALL Study Group.

The Research of Phenylhexyl Isothiocyanate’s Influence on p16 Gene Methylation of Leukaemia Cell

BIM Regulates Prednisolone-Induced Apoptosis in B-Lineage ALL: A Potential Biomarker.

The Effect of Phenylhexyl Isothiocyanate on Drug Resistance of K562/A02 Cell Line

Expression of Hypoxia-Inducible Factor (HIF) Is An Independent Favorable Prognostic Factor in Diffuse Large B-Cell Lymphoma (DLBCL) Treated with R-CHOP

Gene Expression Profiling of Paired Pre- and Post-Prednisolone (PRED) BM Samples from Childhood ALL Identifies Robust Signatures for PRED Response and Eventual Outcome.

Genetic Polymorphisms in the Folate Pathway and Risk of Childhood Acute Lymphoblastic Leukemia (ALL): MTHFR, MTHFD1, RFC1 and TS.

A New Genotyping Chip for Childhood ALL: Using a Novel Multiplex Allele-Specific Primer Extension Strategy To Detect Twelve Polymorphisms in Six Genes Encoding for Drug-Metabolizing Enzymes.

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American Society of Hematology

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American Society of Hematology

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