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Journal Articles

Type I interferon is induced by hemolysis and drives antibody-mediated erythrophagocytosis in sickle cell disease

Yunfeng Liu, Mouli Pal, Weili Bao, Patricia A. Shi, Cheryl A. Lobo, Xiuli An, Deepa Manwani, Hui Zhong, Karina Yazdanbakhsh

Blood (2021) 138 (13): 1162–1171.

https://doi.org/10.1182/blood.2021011629

Published: 2021

Includes: Supplemental data

Journal Articles

Heme: driver of erythrocyte elimination

Jordan D. Dimitrov, Lubka T. Roumenina

Blood (2021) 138 (13): 1092–1094.

https://doi.org/10.1182/blood.2021012875

Published: 2021

Journal Articles

Macrophage metabolic adaptation to heme detoxification involves CO-dependent activation of the pentose phosphate pathway

Gael F. P. Bories, Scott Yeudall, Vlad Serbulea, Todd E. Fox, Brant E. Isakson, Norbert Leitinger

Blood (2020) 136 (13): 1535–1548.

https://doi.org/10.1182/blood.2020004964

Published: 2020

Includes: Supplemental data

Journal Articles

Diamond-Blackfan anemia

Lydie Da Costa, Thierry Leblanc, Narla Mohandas

Blood (2020) 136 (11): 1262–1273.

https://doi.org/10.1182/blood.2019000947

Published: 2020

Journal Articles

Heme induces rapid endothelial barrier dysfunction via the MKK3/p38MAPK axis

Joel James, Anup Srivastava, Mathews Valuparampil Varghese, Cody A. Eccles, Marina Zemskova, Olga Rafikova, Ruslan Rafikov

Blood (2020) 136 (6): 749–754.

https://doi.org/10.1182/blood.2019003986

Published: 2020

Includes: Supplemental data

Journal Articles

Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease

Erica M. Sparkenbaugh, Chunsheng Chen, Tomasz Brzoska, Julia Nguyen, Shaobin Wang, Gregory M. Vercellotti, Nigel S. Key, Prithu Sundd, John D. Belcher, Rafal Pawlinski

Blood (2020) 135 (20): 1783–1787.

https://doi.org/10.1182/blood.2019003543

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Heme A1M’ed at the kidney in sickle cell disease

Santosh L. Saraf

Blood (2020) 135 (13): 979–981.

https://doi.org/10.1182/blood.2020005134

Published: 2020

Journal Articles

Hemopexin deficiency promotes acute kidney injury in sickle cell disease

Solomon F. Ofori-Acquah, Rimi Hazra, Oluwaseun O. Orikogbo, Danielle Crosby, Bethany Flage, Ezekiel B. Ackah, Diane Lenhart, Roderick J. Tan, Dario A. Vitturi, Vivian Paintsil, Ellis Owusu-Dabo, Samit Ghosh, in collaboration with the SickleGenAfrica Network

Blood (2020) 135 (13): 1044–1048.

https://doi.org/10.1182/blood.2019002653

Published: 2020

Includes: Supplemental data

Journal Articles

Heme-regulated eIF2α kinase in erythropoiesis and hemoglobinopathies

Jane-Jane Chen, Shuping Zhang

Blood (2019) 134 (20): 1697–1707.

https://doi.org/10.1182/blood.2019001915

Published: 2019

Journal Articles

NCOA4 Expression in Hepatic Cells Is Upregulated Under Physiological and Pathophysiological Conditions Associated with Hypoxia

Xiuqi Li, MS, Larisa Lozovatsky, MS, Karin E. Finberg, MD PhD

Blood (2019) 134 (Supplement_1): 431.

https://doi.org/10.1182/blood-2019-130858

Published: 2019

Journal Articles

Dnmt3a Mutation Confers a Selective Advantage Specifically to Cells within the Long-Term Hematopoietic Stem Cell (LT-HSC) Compartment

Elizabeth Eudy, BS, Matthew Loberg, BA, Rebecca Bell, BA, Tim Stearns, Jennifer Trowbridge, PhD

Blood (2019) 134 (Supplement_1): 448.

https://doi.org/10.1182/blood-2019-124540

Published: 2019

Journal Articles

Enasidenib Drives Maturation of Human Erythroid Precursors Independently of IDH2

Ritika Dutta, BS, Tian Y Zhang, MD PhD, Thomas Koehnke, MD, Daniel Thomas, MD PhD, Eric Gars, MD, Melissa Stafford, Yusuke Nakauchi, MD PhD, Satinder Kaur, BS, Raymond Yin, Anupama Narla, MD, Ravindra Majeti, MD PhD

Blood (2019) 134 (Supplement_1): 540.

https://doi.org/10.1182/blood-2019-124551

Published: 2019

Journal Articles

SLC20A1 at the Interface between Macrophages and Red Blood Cells

Federica Quattrone, MSc, Riem Gawish, PhD, Rui Martins, PhD, Anna-Dorothea Gorki, PhD, Martin Watzenboeck, MD, Anastasiya Hladik, Karin Lakovits, Manuele Rebsamen, PhD, Enrico Girardi, PhD, Giulio Superti-Furga, PhD, Sylvia Knapp, MD PhD

Blood (2019) 134 (Supplement_1): 428.

https://doi.org/10.1182/blood-2019-123758

Published: 2019

Journal Articles

Regulation of Erythroid Heme Synthesis By the Mitochondrial Clpx Unfoldase

Catherine Rondelli, Aiden Danoff, Hector Bergonia, Samantha Gillis, Julia Free, John D. Phillips, PhD, Yvette Y Yien, PhD

Blood (2019) 134 (Supplement_1): 427.

https://doi.org/10.1182/blood-2019-132039

Published: 2019

Journal Articles

Informing Clinical Decision and Policy Making in Blood Related Disorders Using Targeted Next Generation Sequencing

Betoul Baz, PhD, Tarek Owaidah, MDFRCPA, Majed Dasouki, MD, Mohammed Abouelhoda, PhD, Dorota Monies, PhD, Nada Al Tassan, PhD

Blood (2019) 134 (Supplement_1): 5776.

https://doi.org/10.1182/blood-2019-122370

Published: 2019

Journal Articles

Evaluation of the Functional Effects of an African American Glucose-6-Phosphate Dehydrogenase (G6PD) Polymorphism (Val68Met) on RBC Hemolytic Propensity and Post-Transfusion Recovery in a Humanized Mouse Model

Ling Wang, MD PhD, Benjamin Zuchelkowski, Derek Sinchar, Minying Yang, Sebastien Gingras, Tamir Kanias, PhD, Janet S Lee, Daniel Kim-Shapiro, Grier Page, PhD BS, MS, Mark T Gladwin, MD

Blood (2019) 134 (Supplement_1): 102.

https://doi.org/10.1182/blood-2019-124926

Published: 2019

Journal Articles

Evaluating Metabolic Regulation of Human Erythropoiesis By Profiling Nutrient Transporter Expression

David Justus, MD, Hongxia Yan, MS, John Hale, PhD, Lionel Blanc, PhD, Floriane Bitaudeau, MS, Vincent Petit, DVM, PhD, Sandrina Kinet, PhD, Marc Sitbon, PhD, Naomi Taylor, MD PhD, Mohandas Narla, DSc

Blood (2019) 134 (Supplement_1): 342.

https://doi.org/10.1182/blood-2019-124380

Published: 2019

Journal Articles

A Phase 1 Dose-Escalation Study of Adding Venetoclax to a Reduced Intensity Conditioning (RIC) Regimen Prior to Allogeneic Hematopoietic Cell Transplantation for Patients with High Risk Myeloid Malignancies

Blood (2019) 134 (Supplement_1): 258.

https://doi.org/10.1182/blood-2019-126172

Published: 2019

Journal Articles

Increased Release of Soluble MD-2 in Sickle Cell Disease and Its Role in Pro-Inflammatory Signaling in Endothelial Cells

Ping Zhang, PhD, John D Belcher, PhD, Julia Nguyen, Fuad Abdulla, Gregory M Vercellotti, MD

Blood (2019) 134 (Supplement_1): 208.

https://doi.org/10.1182/blood-2019-122912

Published: 2019

Journal Articles

Identification of a Heme Activation Site on the MD-2/TLR4 Complex

John D Belcher, PhD, Ping Zhang, PhD, Julia Nguyen, Zachary Monroe Kiser, BS, PhD, John O Trent, PhD, Gregory M Vercellotti, MD

Blood (2019) 134 (Supplement_1): 209.

https://doi.org/10.1182/blood-2019-123788

Published: 2019

NARROW

Type I interferon is induced by hemolysis and drives antibody-mediated erythrophagocytosis in sickle cell disease

Heme: driver of erythrocyte elimination

Macrophage metabolic adaptation to heme detoxification involves CO-dependent activation of the pentose phosphate pathway

Diamond-Blackfan anemia

Heme induces rapid endothelial barrier dysfunction via the MKK3/p38MAPK axis

Thrombin activation of PAR-1 contributes to microvascular stasis in mouse models of sickle cell disease

Heme A1M’ed at the kidney in sickle cell disease

Hemopexin deficiency promotes acute kidney injury in sickle cell disease

Heme-regulated eIF2α kinase in erythropoiesis and hemoglobinopathies

NCOA4 Expression in Hepatic Cells Is Upregulated Under Physiological and Pathophysiological Conditions Associated with Hypoxia

Dnmt3a Mutation Confers a Selective Advantage Specifically to Cells within the Long-Term Hematopoietic Stem Cell (LT-HSC) Compartment

Enasidenib Drives Maturation of Human Erythroid Precursors Independently of IDH2

SLC20A1 at the Interface between Macrophages and Red Blood Cells

Regulation of Erythroid Heme Synthesis By the Mitochondrial Clpx Unfoldase

Informing Clinical Decision and Policy Making in Blood Related Disorders Using Targeted Next Generation Sequencing

Evaluation of the Functional Effects of an African American Glucose-6-Phosphate Dehydrogenase (G6PD) Polymorphism (Val68Met) on RBC Hemolytic Propensity and Post-Transfusion Recovery in a Humanized Mouse Model

Evaluating Metabolic Regulation of Human Erythropoiesis By Profiling Nutrient Transporter Expression

A Phase 1 Dose-Escalation Study of Adding Venetoclax to a Reduced Intensity Conditioning (RIC) Regimen Prior to Allogeneic Hematopoietic Cell Transplantation for Patients with High Risk Myeloid Malignancies

Increased Release of Soluble MD-2 in Sickle Cell Disease and Its Role in Pro-Inflammatory Signaling in Endothelial Cells

Identification of a Heme Activation Site on the MD-2/TLR4 Complex

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American Society of Hematology

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ASH Publications

American Society of Hematology

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