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Journal Articles

RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells

Brian Estevez, Sara Borst, Danuta Jarocha, Varun Sudunagunta, Michael Gonzalez, James Garifallou, Hakon Hakonarson, Peng Gao, Kai Tan, Paul Liu, Sumedha Bagga, Nicholas Holdreith, Wei Tong, Nancy Speck, Deborah L. French, Paul Gadue, Mortimer Poncz

Blood (2021) 137 (19): 2662–2675.

https://doi.org/10.1182/blood.2020006389

Published: 2021

Includes: Supplemental data

Journal Articles

Increased B4GALT1 expression is associated with platelet surface galactosylation and thrombopoietin plasma levels in MPNs

Christian A. Di Buduo, Silvia Giannini, Vittorio Abbonante, Vittorio Rosti, Karin M. Hoffmeister, Alessandra Balduini

Blood (2021) 137 (15): 2085–2089.

https://doi.org/10.1182/blood.2020007265

Published: 2021

Includes: Supplemental data

Journal Articles

Role of Thrombopoietin in Stimulating Megakaryopoiesis of ITP Patients Via Rescuing Vascular Niche

Yingying Jiao, Graduate Student, Xiaoyuan Zeng, Graduate Student, Zongpeng Li, Graduate Student, Beng H Chong, MBBS, PhD, Yujiao Zhang, Graduate Student, Jieyu Ye

Blood (2019) 134 (Supplement_1): 1063.

https://doi.org/10.1182/blood-2019-125679

Published: 2019

Journal Articles

Tropomyosin 1 Genetically Constrains in Vitro Megakaryopoiesis

Christopher Thom, MD PhD, Chintan Jobaliya, Kimberly Lorenz, PhD, Jean Ann Maguire, PhD, Alyssa Gagne, Paul Gadue, PhD, Deborah L French, PhD, Benjamin F Voight, PhD

Blood (2019) 134 (Supplement_1): 3612.

https://doi.org/10.1182/blood-2019-121538

Published: 2019

Journal Articles

Studying the Role of ETV6 in Megakaryopoiesis and Thrombopoiesis Using a Novel CRISPR-Cas9 Halotag Genome Editing Strategy

Marlie H Fisher, Leila J. Noetzli, PhD, Michael Callaghan, MD, Walter H. Kahr, MDPhDFRCPC, Jesse W Rowley, PhD, Jorge Di Paola, MD

Blood (2019) 134 (Supplement_1): 2468.

https://doi.org/10.1182/blood-2019-131967

Published: 2019

Journal Articles

Megakaryopoiesis and Platelet-Innate Immune Cell Interactions Are Developmentally Regulated

Kathleen E. McGrath, PhD, Catherman C Seana, MS, Zachary T Hilt, MS, Katherine H Fegan, MS, Paul D. Kingsley, PhD, Leah A Vitt, BS, Massiel Chavez Stolla, PhD, Craig N. Morrell, PhD, James Palis, MD

Blood (2019) 134 (Supplement_1): 2470.

https://doi.org/10.1182/blood-2019-131039

Published: 2019

Journal Articles

Dose-Dependent Iron Chelating Effects of Eltrombopag on in Vitro Human Megakaryopoiesis

Zhi-Jian Liu, PhD, Emoke Deschmann, MD, Haley E. Ramsey, PhDMSc, Henry Feldman, Bethan Psaila, MD PhD, Nichola Cooper, MD MRCP, Evangelia Vlachodimtropoulou Koumoutsea, MBBS,PhDBSc, John B. Porter, MA MDFRCP FRCPath, James B. Bussel, MD, Michael Georgieff, MD, Martha Sola-Visner, MD

Blood (2019) 134 (Supplement_1): 2475.

https://doi.org/10.1182/blood-2019-131895

Published: 2019

Journal Articles

The Genome-Wide Impact of Trisomy 21 on DNA Methylation and Its Implications for Hematologic Malignancies

Joseph L. Wiemels, PhD, Ivo S Muskens, Shaobo Li, Priyatama Pandey, Ritu Roy, PhD, Helen M Hansen, BSc, Kimberly D Siegmund, PhD, Beth A Mueller, PhD, Xiaomei Ma, PhD, Catherine Metayer, MD PhD, Adam J de Smith, PhD

Blood (2019) 134 (Supplement_1): 2510.

https://doi.org/10.1182/blood-2019-131455

Published: 2019

Journal Articles

Nascent Transcript and Single Cell Rnaseq Analysis Defines the Mechanism of Action of the LSD1 Inhibitor INCB059872 in Myeloid Leukemia

Gretchen Johnston, Haley E. Ramsey, PhDMSc, Kristy Stengel, PhD, Shilpa Sampathi, PhD, Pankaj Acharya, PhD, Maria Arrate, MSc, Matthew C. Stubbs, PhD, Timothy Burn, PhD, Scott Hiebert, PhD, Michael R. Savona, MD

Blood (2019) 134 (Supplement_1): 2509.

https://doi.org/10.1182/blood-2019-130458

Published: 2019

Journal Articles

Transcriptional and Spatial Heterogeneity of Mouse Megakaryocytes at Single-Cell Resolution

Shu Sun, BS, Chen Jin, PhD, Yueying Li, MD, Jia Si, Yueli Cui, Matthew T. Rondina, MD, Fuchou Tang, PhD, Qian-fei Wang, PhD

Blood (2019) 134 (Supplement_1): 275.

https://doi.org/10.1182/blood-2019-129471

Published: 2019

Journal Articles

Excess Serine from the Microenvironment Caused the Impaired Megakaryopoiesis and Thrombocytopia in Multiple Myeloma

Chunmei Kuang, Meijuan Xia, Gang An, MD, Cuicui Liu, Dan Wu, Pei Su, Jingyu Zhang, Jiliang Xia, PhD, Jiaojiao Guo, Xuan Wu, Wei Jia, PhD, Lugui Qiu, MD PhD, Wen Zhou, PhD, Jiaxi Zhou

Blood (2019) 134 (Supplement_1): 4331.

https://doi.org/10.1182/blood-2019-125289

Published: 2019

Journal Articles

Three-D Models for Megakaryopoiesis and Platelet Production

Alessandra Balduini, MD

Blood (2019) 134 (Supplement_1): SCI-36.

https://doi.org/10.1182/blood-2019-121076

Published: 2019

Journal Articles

Ex vivo Engineering of Platelets

Koji Eto, MD

Blood (2019) 134 (Supplement_1): SCI-6.

https://doi.org/10.1182/blood-2019-121116

Published: 2019

Journal Articles

A Novel Approach for Generating Platelet-Delivered FVIII: Role of Transient LRP1 Expression during Megakaryopoiesis

John Tkaczynski, BS, Randolph Lyde, PhD, Hyunsook Ahn, MSc, Francis Ayombil, PhD, Sara Borst, BS, Paul Gadue, PhD, Deborah L French, PhD, Denise Sabatino, PhD, Rodney M. Camire, PhD, Mortimer Poncz, MD

Blood (2019) 134 (Supplement_1): 1102.

https://doi.org/10.1182/blood-2019-124788

Published: 2019

Journal Articles

Azacytidine Inhibits Megakaryopoiesis Via the Induction of Immunogenic RNA Species and Activation of Type-I Interferon Signaling

Ujunwa Cynthia Okoye-Okafor, MS,PhD, Komal Kumar Javarappa, PhD, Dimitrios Tsallos, BSc(Hons),MSc, Joseph J Saad, MSc, BSc, Lumie Benard, Victor Thiruthuvanathan, M.S, Sally Cole, Madhuri Tatiparthy, M.S., Stephen Ruiz, B.Sc, Stefanie DeFronzo, Celine Pallaud, PhD, Pedro Marques Ramos, PhD, Amit Verma, MBBS, Aditi Shastri, MD, Caroline A Heckman, PhD, Britta Will, PhD

Blood (2019) 134 (Supplement_1): 1280.

https://doi.org/10.1182/blood-2019-131461

Published: 2019

Journal Articles

Shared roles for Scl and Lyl1 in murine platelet production and function

Sung K. Chiu, Stephanie L. Orive, Mitchell J. Moon, Jesslyn Saw, Sarah Ellis, Benjamin T. Kile, Yizhou Huang, Diego Chacon, John E. Pimanda, Dominik Beck, Justin R. Hamilton, Cedric S. Tremblay, David J. Curtis

Blood (2019) 134 (10): 826–835.

https://doi.org/10.1182/blood.2019896175

Published: 2019

Includes: Supplemental data

Journal Articles

Spatial Regulation of Thrombopoiesis in the Bone Marrow

David Stegner, PhD, Judith van Eeuwijk, PhD, Maximilian G Gorelashvili, Oguzhan Angay, Mike Friedrich, Jürgen Pinnecker, Patrick Schmithausen, Daniela Semeniak, PhD, Harald Schulze, PhD, Christian Brede, PhD, Andreas Beilhack, MD, Bernhard Nieswandt, PhD, Katrin G Heinze

Blood (2018) 132 (Supplement 1): SCI-23.

https://doi.org/10.1182/blood-2018-99-109545

Published: 2018

Journal Articles

Global Chromatin Occupancy and Epigenetic Signature Analysis Reveal New Insights into the Function of GATA1 N-Terminus in Erythropoiesis

Te Ling, PhD, Yehudit Birger, PhD, Monika Stankiewicz, PhD, Nissim Ben-Haim, Itamar Kanter, Tomer Kalisky, Avigail Rein Gil, MD, Neil L Kelleher, PhD, Lihua Zou, PhD, Shai Izraeli, MD, John D. Crispino, PhD MBA

Blood (2018) 132 (Supplement 1): 533.

https://doi.org/10.1182/blood-2018-99-115338

Published: 2018

Journal Articles

Janus Kinase (Jak) 1 Inhibition Affects Both Megakaryopoiesis and Thrombopoiesis

Danuta Jadwiga Jarocha, PhD, Paul Gadue, PhD, Wei Tong, PhD, Robert C Newton, PhD, Mortimer Poncz, MD

Blood (2018) 132 (Supplement 1): 2559.

https://doi.org/10.1182/blood-2018-99-115407

Published: 2018

Journal Articles

The VWRPY Domain Is Essential for RUNX1 Function in Hematopoietic Progenitor Cell Maturation and Megakaryocyte Differentiation

Halah Alkadi, BSc, MSc, MT(ASCP), David McKellar, BS, Tao Zhen, PhD, Tatiana Karpova, PhD, Lisa J Garrett, MS, Yongxing Gao, MS, Anfal A Alsadhan, MS, Erika Mijin Kwon, PhD, James J Greene, PhD, David A Ball, PhD, Linzhao Cheng, PhD, April D Sorrell, MD, Paul P Liu, MD PhD

Blood (2018) 132 (Supplement 1): 1319.

https://doi.org/10.1182/blood-2018-99-113400

Published: 2018

NARROW

RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells

Increased B4GALT1 expression is associated with platelet surface galactosylation and thrombopoietin plasma levels in MPNs

Role of Thrombopoietin in Stimulating Megakaryopoiesis of ITP Patients Via Rescuing Vascular Niche

Tropomyosin 1 Genetically Constrains in Vitro Megakaryopoiesis

Studying the Role of ETV6 in Megakaryopoiesis and Thrombopoiesis Using a Novel CRISPR-Cas9 Halotag Genome Editing Strategy

Megakaryopoiesis and Platelet-Innate Immune Cell Interactions Are Developmentally Regulated

Dose-Dependent Iron Chelating Effects of Eltrombopag on in Vitro Human Megakaryopoiesis

The Genome-Wide Impact of Trisomy 21 on DNA Methylation and Its Implications for Hematologic Malignancies

Nascent Transcript and Single Cell Rnaseq Analysis Defines the Mechanism of Action of the LSD1 Inhibitor INCB059872 in Myeloid Leukemia

Transcriptional and Spatial Heterogeneity of Mouse Megakaryocytes at Single-Cell Resolution

Excess Serine from the Microenvironment Caused the Impaired Megakaryopoiesis and Thrombocytopia in Multiple Myeloma

Three-D Models for Megakaryopoiesis and Platelet Production

Ex vivo Engineering of Platelets

A Novel Approach for Generating Platelet-Delivered FVIII: Role of Transient LRP1 Expression during Megakaryopoiesis

Azacytidine Inhibits Megakaryopoiesis Via the Induction of Immunogenic RNA Species and Activation of Type-I Interferon Signaling

Shared roles for Scl and Lyl1 in murine platelet production and function

Spatial Regulation of Thrombopoiesis in the Bone Marrow

Global Chromatin Occupancy and Epigenetic Signature Analysis Reveal New Insights into the Function of GATA1 N-Terminus in Erythropoiesis

Janus Kinase (Jak) 1 Inhibition Affects Both Megakaryopoiesis and Thrombopoiesis

The VWRPY Domain Is Essential for RUNX1 Function in Hematopoietic Progenitor Cell Maturation and Megakaryocyte Differentiation

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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