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Journal Articles

Therapeutic Targeting of Monokine Production Is a Promising Strategy to Attenuate Cytokine-Release Syndrome in CAR-T Cell Therapy

Muneyoshi Futami, MD PhD, Keisuke Suzuki, MS, Satomi Kato, BS, Yoshio Tahara, MS, Yoichi Imai, MD PhD, Takayuki Mimura, PhD, Yoshihiro Watanabe, PhD, Arinobu Tojo, MD PhD

Blood (2019) 134 (Supplement_1): 2067.

https://doi.org/10.1182/blood-2019-129601

Published: 2019

Journal Articles

ATG and Statins Reduce Incidence of Severe Chronic Gvhd By Distinct Mechanisms Involving CXCL9 and Kynurenine Catabolism

Thomas Luft, MD PhD, Katharina Schmidt, MD, Karl-Heinz Kellner, PhD, Aleksandar Radujkovic, MD, Nicola Lehners, MD, Mark-Alexander Schwarzbich, MD, Ute Hegenbart, MD, Anthony D. Ho, MD, Peter Dreger, MD

Blood (2015) 126 (23): 856.

https://doi.org/10.1182/blood.V126.23.856.856

Published: 2015

Journal Articles

JAK Inhibition Reduces CD25 high CD27 + FOXp3 + T Regulatory Cells and Causes a Silencing Of T Effector Cells In Patients With Myeloproliferative Neoplasms Whilst Promoting a TH17 Phenotype

Clodagh Keohane, MD, Shahram Y Kordasti, MD, PhD, Thomas Seidl, Pilar Perez Abellan, Nicholas Shaun B. Thomas, PhD, Ghulam J Mufti, FRCP, FRCPath, Claire N Harrison, DM, FRCP, FRCPath, Donal McLornan, MD, PhD

Blood (2013) 122 (21): 4092.

https://doi.org/10.1182/blood.V122.21.4092.4092

Published: 2013

Journal Articles

Genetically coupled receptor–ligand pair NKp80-AICL enables autonomous control of human NK cell responses

Sascha N. Klimosch, Yvonne Bartel, Stefan Wiemann, Alexander Steinle

Blood (2013) 122 (14): 2380–2389.

https://doi.org/10.1182/blood-2013-01-479790

Published: 2013

Includes: Supplemental data

Journal Articles

miR-155 regulates IFN-γ production in natural killer cells

Rossana Trotta, Li Chen, David Ciarlariello, Srirama Josyula, Charlene Mao, Stefan Costinean, Lianbo Yu, Jonathan P. Butchar, Susheela Tridandapani, Carlo M. Croce, Michael A. Caligiuri

Blood (2012) 119 (15): 3478–3485.

https://doi.org/10.1182/blood-2011-12-398099

Published: 2012

Journal Articles

Malignant Plasma Cells Responsible for Multiple Myeloma Relapse Are Detectable and Survive Nine Days After High Dose Melphalan: Highlight of An Optimal Therapeutic Window ?

Anouk Caraux, PhD, Laure Vincent, Jerome Moreaux, PhD, Guilhem Requirand, Caroline Bret, PharmD, PhD, Jean-Luc Veyrune, PhD, Christophe Duperray, Salahedine Bouhya, MD, Jean-Francois Rossi, MD, PhD, Bernard Klein, PhD

Blood (2011) 118 (21): 131.

https://doi.org/10.1182/blood.V118.21.131.131

Published: 2011

Journal Articles

Induction of a CTL-Like Phenotype In B-CLL Cells Stimulated with Interleukin 21 and CpG Oligodeoxynucleotides

Bernd Jahrsdoerfer, MD, Sue E Blackwell, Magdalena Hagn, MD, Verena Ebel, Thamara Beyer, Kai Sontheimer, Karen Dahlke, George Weiner, MD, Thomas Simmet, MD

Blood (2010) 116 (21): 3906.

https://doi.org/10.1182/blood.V116.21.3906.3906

Published: 2010

Journal Articles

Hlx homeobox transcription factor negatively regulates interferon-γ production in monokine-activated natural killer cells

Brian Becknell, Tiffany L. Hughes, Aharon G. Freud, Bradley W. Blaser, Jianhua Yu, Rossana Trotta, Hsiaoyin C. Mao, Marie L. Caligiuri de Jesús, Mohamad Alghothani, Don M. Benson, Jr, Amy Lehman, David Jarjoura, Danilo Perrotti, Michael D. Bates, Michael A. Caligiuri

Blood (2006) 109 (6): 2481–2487.

https://doi.org/10.1182/blood-2006-10-050096

Published: 2006

Journal Articles

Relationship between Fatigue and Cytokine Levels in Patients Age 50+ with Acute Myeloid Leukemia (AML).

Abbas H. Panju, David Kelvin, PhD, Mark D. Minden, MD, PhD, Shabbir M.H. Alibhai, MD, MSc

Blood (2006) 108 (11): 4507.

https://doi.org/10.1182/blood.V108.11.4507.4507

Published: 2006

Journal Articles

In Vitro and In Vivo Evidence That the PP2A Inhibitor SET Regulates IFN-γ Production in Monokine-Stimulated Natural Killer Cells.

Rossana Trotta, PhD, Jessica Dal Col, PhD, Jeffrey Allard, II, BS, Paolo Neviani, PhD, Ramasamy Santhanam, PhD, Hsiaoyin Mao, MS, Brian Becknell, PhD, Jianhua Yu, PhD, Aalok Modi, BS, Bradley W. Blaser, PhD, Danilo Perrotti, MD PhD, Michael A. Caligiuri, MD

Blood (2006) 108 (11): 928.

https://doi.org/10.1182/blood.V108.11.928.928

Published: 2006

Journal Articles

Monokine Induced by Interferon-γ (MIG) Serum Levels Are a Marker of Disease Load and Correlate with Prognosis in Multiple Myeloma.

Martin Schreder, MD, Gudrun Koch, Daniel Heintel, MD, Kathrin Strasser-Weippl, MD, Katrin Frischmuth, MD, Ulrich Jaeger, MD, Heinz Ludwig, MD, Niklas Zojer, MD

Blood (2006) 108 (11): 5040.

https://doi.org/10.1182/blood.V108.11.5040.5040

Published: 2006

Journal Articles

BMP4 Induces Changes in Jagged 1 Expression in Bone Marrow Stroma: Association with Induction of Notch Regulated Genes in CD34+Cells.

Sara R. Fagerlie, PhD, Mineo Iwata, PhD, Lynn Graf, PhD, Beverly Torok-Storb, PhD

Blood (2005) 106 (11): 1388.

https://doi.org/10.1182/blood.V106.11.1388.1388

Published: 2005

Journal Articles

Circulating CD56 Bright Natural Killer Cells after Allogeneic Stem Cell Trasnplantation Express Functional TRAIL; Implication for a Novel Target of Immunotherapy.

Sumiko Takao, Takayuki Ishikawa, Katsuyuki Ohmori, Atsumi Ishida, Takashi Uchiyama

Blood (2005) 106 (11): 5403.

https://doi.org/10.1182/blood.V106.11.5403.5403

Published: 2005

Journal Articles

Differential expression of SHIP1 in CD56 bright and CD56 dim NK cells provides a molecular basis for distinct functional responses to monokine costimulation

Rossana Trotta, Robin Parihar, Jianhua Yu, Brian Becknell, Jeffrey Allard, II, Jing Wen, Wei Ding, Hsiaoyin Mao, Susheela Tridandapani, William E. Carson, Michael A. Caligiuri

Blood (2005) 105 (8): 3011–3018.

https://doi.org/10.1182/blood-2004-10-4072

Published: 2005

Journal Articles

Monokine induced by interferon-γ is induced by receptor activator of nuclear factor κB ligand and is involved in osteoclast adhesion and migration

Han Bok Kwak, Soo Woong Lee, Hye Mi Jin, Hyunil Ha, Sang Ho Lee, Sunao Takeshita, Sakae Tanaka, Hyun-Man Kim, Hong-Hee Kim, Zang Hee Lee

Blood (2005) 105 (7): 2963–2969.

https://doi.org/10.1182/blood-2004-07-2534

Published: 2005

Journal Articles

Elucidation of the Molecular Mechanisms by Which Inflammatory and Anti-Inflammatory Monokines Regulate Interferon (IFN)- γ Production.

Jianhua Yu, Brian Becknell, Shujun Liu, Rossana Trotta, Micheal S. Jaung, Tiffany Hughes, Guido Marcucci, Michael B. Weinstein, Michael A. Caligiuri

Blood (2004) 104 (11): 111.

https://doi.org/10.1182/blood.V104.11.111.111

Published: 2004

Journal Articles

Multiple Myeloma Oncogene 1 (MUM1)/Interferon Regulatory Factor 4 (IRF4) Upregulates Monokine Induced by Interferon-gamma (MIG) Gene Expression in B-Cell Malignancy.

Shinsuke Iida, M.D., Miyuki Uranishi, M.D., Ph.D., Takaomi Sanda, M.D., Takashi Ishida, M.D., Emi Tajima, M.D., Masato Ito, M.D., Ph.D., Hirokazu Komatsu, M.D., Hiroshi Inagaki, M.D., Ryuzo Ueda, M.D.

Blood (2004) 104 (11): 1111.

https://doi.org/10.1182/blood.V104.11.1111.1111

Published: 2004

Journal Articles

Increased expression of the inflammatory chemokine CXC chemokine ligand 9/monokine induced by interferon-γ in lymphoid tissues of rhesus macaques during simian immunodeficiency virus infection and acquired immunodeficiency syndrome

Todd A. Reinhart, Beth A. Fallert, Melanie E. Pfeifer, Sonali Sanghavi, Saverio Capuano, III, Premeela Rajakumar, Michael Murphey-Corb, Richard Day, Craig L. Fuller, Todd M Schaefer

Blood (2002) 99 (9): 3119–3128.

https://doi.org/10.1182/blood.V99.9.3119

Published: 2002

Journal Articles

Human natural killer cells: a unique innate immunoregulatory role for the CD56 bright subset

Megan A. Cooper, Todd A. Fehniger, Sarah C. Turner, Kenneth S. Chen, Bobak A. Ghaheri, Tariq Ghayur, William E. Carson, Michael A. Caligiuri

Blood (2001) 97 (10): 3146–3151.

https://doi.org/10.1182/blood.V97.10.3146

Published: 2001

Journal Articles

Interferon-inducible protein 10, monokine induced by interferon gamma, and interferon-inducible T-cell alpha chemoattractant are produced by thymic epithelial cells and attract T-cell receptor (TCR) αβ + CD8 + single-positive T cells, TCRγδ + T cells, and natural killer–type cells in human thymus

Paola Romagnani, Francesco Annunziato, Elena Lazzeri, Lorenzo Cosmi, Chiara Beltrame, Laura Lasagni, Grazia Galli, Michela Francalanci, Roberto Manetti, Fabio Marra, Vittorio Vanini, Enrico Maggi, Sergio Romagnani

Blood (2001) 97 (3): 601–607.

https://doi.org/10.1182/blood.V97.3.601

Published: 2001

NARROW

Therapeutic Targeting of Monokine Production Is a Promising Strategy to Attenuate Cytokine-Release Syndrome in CAR-T Cell Therapy

ATG and Statins Reduce Incidence of Severe Chronic Gvhd By Distinct Mechanisms Involving CXCL9 and Kynurenine Catabolism

JAK Inhibition Reduces CD25 high CD27 + FOXp3 + T Regulatory Cells and Causes a Silencing Of T Effector Cells In Patients With Myeloproliferative Neoplasms Whilst Promoting a TH17 Phenotype

Genetically coupled receptor–ligand pair NKp80-AICL enables autonomous control of human NK cell responses

miR-155 regulates IFN-γ production in natural killer cells

Malignant Plasma Cells Responsible for Multiple Myeloma Relapse Are Detectable and Survive Nine Days After High Dose Melphalan: Highlight of An Optimal Therapeutic Window ?

Induction of a CTL-Like Phenotype In B-CLL Cells Stimulated with Interleukin 21 and CpG Oligodeoxynucleotides

Hlx homeobox transcription factor negatively regulates interferon-γ production in monokine-activated natural killer cells

Relationship between Fatigue and Cytokine Levels in Patients Age 50+ with Acute Myeloid Leukemia (AML).

In Vitro and In Vivo Evidence That the PP2A Inhibitor SET Regulates IFN-γ Production in Monokine-Stimulated Natural Killer Cells.

Monokine Induced by Interferon-γ (MIG) Serum Levels Are a Marker of Disease Load and Correlate with Prognosis in Multiple Myeloma.

BMP4 Induces Changes in Jagged 1 Expression in Bone Marrow Stroma: Association with Induction of Notch Regulated Genes in CD34+Cells.

Circulating CD56 Bright Natural Killer Cells after Allogeneic Stem Cell Trasnplantation Express Functional TRAIL; Implication for a Novel Target of Immunotherapy.

Differential expression of SHIP1 in CD56 bright and CD56 dim NK cells provides a molecular basis for distinct functional responses to monokine costimulation

Monokine induced by interferon-γ is induced by receptor activator of nuclear factor κB ligand and is involved in osteoclast adhesion and migration

Elucidation of the Molecular Mechanisms by Which Inflammatory and Anti-Inflammatory Monokines Regulate Interferon (IFN)- γ Production.

Multiple Myeloma Oncogene 1 (MUM1)/Interferon Regulatory Factor 4 (IRF4) Upregulates Monokine Induced by Interferon-gamma (MIG) Gene Expression in B-Cell Malignancy.

Increased expression of the inflammatory chemokine CXC chemokine ligand 9/monokine induced by interferon-γ in lymphoid tissues of rhesus macaques during simian immunodeficiency virus infection and acquired immunodeficiency syndrome

Human natural killer cells: a unique innate immunoregulatory role for the CD56 bright subset

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American Society of Hematology

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ASH Publications

American Society of Hematology

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