Lamiae Grimaldi-Bensouda,for the PGRx Immune Thrombocytopenia Study Group,Marc Michel,for the PGRx Immune Thrombocytopenia Study Group,Elodie Aubrun,for the PGRx Immune Thrombocytopenia Study Group,Pamela Leighton,for the PGRx Immune Thrombocytopenia Study Group,Jean-Francois Viallard,for the PGRx Immune Thrombocytopenia Study Group,Daniel Adoue,for the PGRx Immune Thrombocytopenia Study Group,Nadine Magy-Bertrand,for the PGRx Immune Thrombocytopenia Study Group,Guillaume Tisserand,for the PGRx Immune Thrombocytopenia Study Group,Mehdi Khellaf,for the PGRx Immune Thrombocytopenia Study Group,Jean-Marc Durand,for the PGRx Immune Thrombocytopenia Study Group,Philippe Quittet,for the PGRx Immune Thrombocytopenia Study Group,Olivier Fain,for the PGRx Immune Thrombocytopenia Study Group,Bernard Bonnotte,for the PGRx Immune Thrombocytopenia Study Group,Anne Sophie Morin,for the PGRx Immune Thrombocytopenia Study Group,Nicolas Limal,for the PGRx Immune Thrombocytopenia Study Group,Nathalie Costedoat-Chalumeau,for the PGRx Immune Thrombocytopenia Study Group,Nathalie Morel,for the PGRx Immune Thrombocytopenia Study Group,Brigitte Pan-Petesch,for the PGRx Immune Thrombocytopenia Study Group,Olivier Decaux,for the PGRx Immune Thrombocytopenia Study Group,Matthieu Mahevas,for the PGRx Immune Thrombocytopenia Study Group,Michel Ruel,for the PGRx Immune Thrombocytopenia Study Group,Karim Sacre,for the PGRx Immune Thrombocytopenia Study Group,Francois Lefrere,for the PGRx Immune Thrombocytopenia Study Group,Lucien Abenhaim,for the PGRx Immune Thrombocytopenia Study Group,Bertrand Godeau,for the PGRx Immune Thrombocytopenia Study Group

View Articletitled, A case-control study to assess the risk of immune thrombocytopenia associated with vaccines

Supplemental data

Bacteria differentially induce degradation of Bcl-x_L, a survival protein, by human platelets

Bjoern F. Kraemer,Robert A. Campbell,Hansjörg Schwertz,Zechariah G. Franks,Adriana Vieira de Abreu,Katharina Grundler,Benjamin T. Kile,Bijaya K. Dhakal,Matthew T. Rondina,Walter H. A. Kahr,Matthew A. Mulvey,Robert C. Blaylock,Guy A. Zimmerman,Andrew S. Weyrich

View Articletitled, Bacteria differentially induce degradation of Bcl-xL, a survival protein, by human platelets

Supplemental data

The VPS33B-binding protein VPS16B is required in megakaryocyte and platelet α-granule biogenesis

Denisa Urban,Ling Li,Hilary Christensen,Fred G. Pluthero,Shao Zun Chen,Michael Puhacz,Parvesh M. Garg,Kiran K. Lanka,James J. Cummings,Helmut Kramer,James D. Wasmuth,John Parkinson,Walter H. A. Kahr

View Articletitled, The VPS33B-binding protein VPS16B is required in megakaryocyte and platelet α-granule biogenesis

Supplemental data

Red Cells, Iron, and Erythropoiesis

Erythrocyte microparticles can induce kidney vaso-occlusions in a murine model of sickle cell disease

Stéphane M. Camus,Blandine Gausserès,Philippe Bonnin,Laurent Loufrani,Linda Grimaud,Dominique Charue,Joao A. De Moraes,Jean-Marie Renard,Alain Tedgui,Chantal M. Boulanger,Pierre-Louis Tharaux,Olivier P. Blanc-Brude

View Articletitled, Erythrocyte microparticles can induce kidney vaso-occlusions in a murine model of sickle cell disease

Supplemental data

Thrombosis and Hemostasis

Identification of functionally important residues in TFPI Kunitz domain 3 required for the enhancement of its activity by protein S
Brief Report

Josefin Ahnström,Helena M. Andersson,Verity Hockey,Yiran Meng,Thomas A. J. McKinnon,Tsutomu Hamuro,James T. B. Crawley,David A. Lane

View Articletitled, Identification of functionally important residues in TFPI Kunitz domain 3 required for the enhancement of its activity by protein S

Supplemental data

Vascular Biology

The microRNA-30 family targets DLL4 to modulate endothelial cell behavior during angiogenesis

Gemma Bridge,Rui Monteiro,Stephen Henderson,Victoria Emuss,Dimitris Lagos,Dimitra Georgopoulou,Roger Patient,Chris Boshoff

View Articletitled, The microRNA-30 family targets DLL4 to modulate endothelial cell behavior during angiogenesis

Supplemental data

The vitamin K–dependent anticoagulant factor, protein S, inhibits multiple VEGF-A–induced angiogenesis events in a Mer- and SHP2-dependent manner

Sylvain Fraineau,Arnaud Monvoisin,Jonathan Clarhaut,Julie Talbot,Claire Simonneau,Chryso Kanthou,Sandip M. Kanse,Michel Philippe,Omar Benzakour

View Articletitled, The vitamin K–dependent anticoagulant factor, protein S, inhibits multiple VEGF-A–induced angiogenesis events in a Mer- and SHP2-dependent manner

Supplemental data

Correspondence

The revised IPSS is a powerful tool to evaluate the outcome of MDS patients treated with azacitidine: the GFM experience

Mathilde Lamarque,Sophie Raynaud,Raphael Itzykson,Sylvain Thepot,Bruno Quesnel,Francois Dreyfus,Odile Beyne Rauzy,Pascal Turlure,Norbert Vey,Christian Recher,Caroline Dartigeas,Laurence Legros,Jacques Delaunay,Sorin Visanica,Aspasia Stamatoullas,Pierre Fenaux,Lionel Adès

View Articletitled, The revised IPSS is a powerful tool to evaluate the outcome of MDS patients treated with azacitidine: the GFM experience

CD8⁺ T cells far predominate over CD4⁺ T cells in healthy immune response to Epstein-Barr virus infected lymphoblastoid cell lines

Michael P. Pender,Peter A. Csurhes,Casey M. M. Pfluger,Scott R. Burrows

View Articletitled, CD8+ T cells far predominate over CD4+ T cells in healthy immune response to Epstein-Barr virus infected lymphoblastoid cell lines

Significant weight gain in patients with chronic myeloid leukemia after imatinib therapy

Elvis Aduwa,Richard Szydlo,David Marin,Letizia Foroni,Alistair Reid,John Goldman,Jane F. Apperley,Dragana Milojkovic

View Articletitled, Significant weight gain in patients with chronic myeloid leukemia after imatinib therapy

Limited efficacy and tolerance of imatinib mesylate in steroid-refractory sclerodermatous chronic GVHD

Adèle de Masson,Jean-David Bouaziz,Régis Peffault de Latour,Sebastian Wittnebel,Patricia Ribaud,Marie-Thérèse Rubio,Jean-Baptiste Micol,Felipe Suarez,Stéphanie Nguyen,Jean-Hugues Dalle,Karima Yakouben,Marie Robin,Aliénor Xhaard,Lionel Adès,Jean-Henri Bourhis,Michel Rybojad,Martine Bagot,Gérard Socié

View Articletitled, Limited efficacy and tolerance of imatinib mesylate in steroid-refractory sclerodermatous chronic GVHD

Blood Reflections

Venous Return

Adam Possner

View Articletitled, Venous Return

Cover Image

Cover Image

Abnormal red blood cells from mice with sickle cell disease after treatment with thrombospondin-1 peptide 4N1-1 (scanning electron microscopy). Irreversible sickle-shaped cells can be observed as well as echinocytes with abnormally long and numerous spicules. See the article by Camus et al on page 5050.
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Inside Blood

Blood Work

Perspectives

Review Article

Clinical Trials and Observations

Prediagnosis biomarkers of insulin-like growth factor-1, insulin, and interleukin-6 dysregulation and multiple myeloma risk in the Multiple Myeloma Cohort Consortium Clinical Trials & Observations

Evaluation of participants with suspected heritable platelet function disorders including recommendation and validation of a streamlined agonist panel Clinical Trials & Observations

Hematopoiesis and Stem Cells

Immunobiology

Lymphoid Neoplasia

Myeloid Neoplasia

Phase 2 study of the lenalidomide and azacitidine combination in patients with higher-risk myelodysplastic syndromes Clinical Trials & Observations

Phagocytes, Granulocytes, and Myelopoiesis

The biology of nematode- and IL4Rα-dependent murine macrophage polarization in vivo as defined by RNA-Seq and targeted lipidomics e-blood

Platelets and Thrombopoiesis

A case-control study to assess the risk of immune thrombocytopenia associated with vaccines Clinical Trials & Observations

Red Cells, Iron, and Erythropoiesis

Thrombosis and Hemostasis

Identification of functionally important residues in TFPI Kunitz domain 3 required for the enhancement of its activity by protein S Brief Report

Vascular Biology

Correspondence

Blood Reflections

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American Society of Hematology

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Prediagnosis biomarkers of insulin-like growth factor-1, insulin, and interleukin-6 dysregulation and multiple myeloma risk in the Multiple Myeloma Cohort Consortium
Clinical Trials & Observations

Evaluation of participants with suspected heritable platelet function disorders including recommendation and validation of a streamlined agonist panel
Clinical Trials & Observations

Phase 2 study of the lenalidomide and azacitidine combination in patients with higher-risk myelodysplastic syndromes
Clinical Trials & Observations

The biology of nematode- and IL4Rα-dependent murine macrophage polarization in vivo as defined by RNA-Seq and targeted lipidomics
e-blood

A case-control study to assess the risk of immune thrombocytopenia associated with vaccines
Clinical Trials & Observations

Identification of functionally important residues in TFPI Kunitz domain 3 required for the enhancement of its activity by protein S
Brief Report