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Issue Archive

Volume 126, Issue 12
September 17 2015
Issue Cover

Table of Contents

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
Risk organ + LCH gets the one-two punch?
Clinical Trials & Observations
Kimo C. Stine
View Articletitled, Risk organ + LCH gets the one-two punch?
INSIDE BLOOD COMMENTARY
Nasal NK/T-cell lymphoma: RT, CT, or both
Clinical Trials & Observations
Eric Tse,Yok-Lam Kwong
View Articletitled, Nasal NK/T-cell lymphoma: RT, CT, or both
INSIDE BLOOD COMMENTARY
Myeloma escape from immunity: an “inside” job
Aaron P. Rapoport
View Articletitled, Myeloma escape from immunity: an “inside” job
INSIDE BLOOD COMMENTARY
Polyphosphates rock! A role in thrombosis?
Dougald M. Monroe
View Articletitled, Polyphosphates rock! A role in thrombosis?
INSIDE BLOOD COMMENTARY
Does GVHD make amateurs out of professional APCs?
Alan M. Hanash
View Articletitled, Does GVHD make amateurs out of professional APCs?

CLINICAL TRIALS AND OBSERVATIONS

Prognostic value of circulating Bcl-2/IgH levels in patients with follicular lymphoma receiving first-line immunochemotherapy
Clinical Trials & Observations
Fabian Zohren,Ingmar Bruns,Sabrina Pechtel,Thomas Schroeder,Roland Fenk,Akos Czibere,Georg Maschmeyer,Dorothea Kofahl-Krause,Norbert Niederle,Gerhard Heil,Christoph Losem,Manfred Welslau,Wolfram Brugger,Ulrich Germing,Ralf Kronenwett,Juergen Barth,Mathias J. Rummel,Rainer Haas,Guido Kobbe
View Articletitled, Prognostic value of circulating Bcl-2/IgH levels in patients with follicular lymphoma receiving first-line immunochemotherapy
Supplemental data
Cladribine and cytarabine in refractory multisystem Langerhans cell histiocytosis: results of an international phase 2 study
Clinical Trials & Observations
Jean Donadieu,Frederic Bernard,Max van Noesel,Mohamed Barkaoui,Odile Bardet,Rosella Mura,Maurizio Arico,Christophe Piguet,Virginie Gandemer,Corinne Armari Alla,Niels Clausen,Eric Jeziorski,Anne Lambilliote,Sheila Weitzman,Jan Inge Henter,Cor Van Den Bos,the Salvage Group of the Histiocyte Society
View Articletitled, Cladribine and cytarabine in refractory multisystem Langerhans cell histiocytosis: results of an international phase 2 study
Supplemental data
Risk-adapted therapy for early-stage extranodal nasal-type NK/T-cell lymphoma: analysis from a multicenter study
CME Clinical Trials & Observations
Yong Yang,Yuan Zhu,Jian-Zhong Cao,Yu-Jing Zhang,Li-Ming Xu,Zhi-Yong Yuan,Jun-Xin Wu,Wei Wang,Tao Wu,Bing Lu,Su-Yu Zhu,Li-Ting Qian,Fu-Quan Zhang,Xiao-Rong Hou,Ye-Xiong Li
View Articletitled, Risk-adapted therapy for early-stage extranodal nasal-type NK/T-cell lymphoma: analysis from a multicenter study
Supplemental data

HEMATOPOIESIS AND STEM CELLS

Transmembrane TNF-α preferentially expressed by leukemia stem cells and blasts is a potent target for antibody therapy
Xiaoxi Zhou,Shiqiu Zhou,Baihua Li,Qinlu Li,Lili Gao,Dan Li,Quan Gong,Li Zhu,Jue Wang,Na Wang,Liang Huang,Lei Zhao,Zhuoya Li,Jianfeng Zhou
View Articletitled, Transmembrane TNF-α preferentially expressed by leukemia stem cells and blasts is a potent target for antibody therapy
Supplemental data

LYMPHOID NEOPLASIA

Dendritic cells accumulate in the bone marrow of myeloma patients where they protect tumor plasma cells from CD8+ T-cell killing
Patrizia Leone,Simona Berardi,Maria Antonia Frassanito,Roberto Ria,Valli De Re,Sebastiano Cicco,Stefano Battaglia,Paolo Ditonno,Franco Dammacco,Angelo Vacca,Vito Racanelli
View Articletitled, Dendritic cells accumulate in the bone marrow of myeloma patients where they protect tumor plasma cells from CD8<sup>+</sup> T-cell killing
Topical resiquimod can induce disease regression and enhance T-cell effector functions in cutaneous T-cell lymphoma
Clinical Trials & Observations
Alain H. Rook,Joel M. Gelfand,Maria Wysocka,Andrea B. Troxel,Bernice Benoit,Christian Surber,Rosalie Elenitsas,Marie A. Buchanan,Deborah S. Leahy,Rei Watanabe,Ilan R. Kirsch,Ellen J. Kim,Rachael A. Clark
View Articletitled, Topical resiquimod can induce disease regression and enhance T-cell effector functions in cutaneous T-cell lymphoma
Supplemental data

MYELOID NEOPLASIA

Depletion of the chromatin remodeler CHD4 sensitizes AML blasts to genotoxic agents and reduces tumor formation
Justin Sperlazza,Mohamed Rahmani,Jason Beckta,Mandy Aust,Elisa Hawkins,Shou Zhen Wang,Sheng Zu Zhu,Shreya Podder,Catherine Dumur,Kellie Archer,Steven Grant,Gordon D. Ginder
View Articletitled, Depletion of the chromatin remodeler CHD4 sensitizes AML blasts to genotoxic agents and reduces tumor formation
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Cytokinesis failure in RhoA-deficient mouse erythroblasts involves actomyosin and midbody dysregulation and triggers p53 activation
Diamantis G. Konstantinidis,Katie M. Giger,Mary Risinger,Suvarnamala Pushkaran,Ping Zhou,Phillip Dexheimer,Satwica Yerneni,Paul Andreassen,Ursula Klingmüller,James Palis,Yi Zheng,Theodosia A. Kalfa
View Articletitled, Cytokinesis failure in RhoA-deficient mouse erythroblasts involves actomyosin and midbody dysregulation and triggers p53 activation
Supplemental data

THROMBOSIS AND HEMOSTASIS

Platelets induce apoptosis via membrane-bound FasL
Rebecca I. Schleicher,Frank Reichenbach,Peter Kraft,Anil Kumar,Mario Lescan,Franziska Todt,Kerstin Göbel,Ingo Hilgendorf,Tobias Geisler,Axel Bauer,Marcus Olbrich,Martin Schaller,Sebastian Wesselborg,Lorraine O’Reilly,Sven G. Meuth,Klaus Schulze-Osthoff,Meinrad Gawaz,Xuri Li,Christoph Kleinschnitz,Frank Edlich,Harald F. Langer
View Articletitled, Platelets induce apoptosis via membrane-bound FasL
Supplemental data
FXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flow
Shu Zhu,Richard J. Travers,James H. Morrissey,Scott L. Diamond
View Articletitled, FXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flow
Supplemental data

TRANSPLANTATION

Acute GVHD results in a severe DC defect that prevents T-cell priming and leads to fulminant cytomegalovirus disease in mice
Matthew E. Wikstrom,Peter Fleming,Rachel D. Kuns,Iona S. Schuster,Valentina Voigt,Gregory Miller,Andrew D. Clouston,Siok-Keen Tey,Christopher E. Andoniou,Geoffrey R. Hill,Mariapia A. Degli-Esposti
View Articletitled, Acute GVHD results in a severe DC defect that prevents T-cell priming and leads to fulminant cytomegalovirus disease in mice
Supplemental data

BLOOD WORK

Cystine crystals in bone marrow aspirate
Laurie Monier,Laurent Mauvieux
View Articletitled, Cystine crystals in bone marrow aspirate
Diagnosis of hantavirus cardiopulmonary syndrome with peripheral blood film
Oksana Prokopchuk-Gauk,Artur Szkotak
View Articletitled, Diagnosis of hantavirus cardiopulmonary syndrome with peripheral blood film

CONTINUING MEDICAL EDUCATION (CME) QUESTIONS

Risk-adapted therapy for extranodal NKTCL
CME
View Articletitled, Risk-adapted therapy for extranodal NKTCL
All Issues

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