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        Safety and activity of BTK inhibitor ibrutinib combined with ofatumumab in chronic lymphocytic leukemia: a phase 1b/2 study
        
        
            
        
    
        
                
            
    
    
    
                    
        
        Critical analysis of the stringent complete response in multiple myeloma: contribution of sFLC and bone marrow clonality
        
        
            
        
    
        
                
            
    
    
    
        
        
     
    
                     
    
                     
    
                    
        
        
     
    
                    
                    
        
        Factor VIII gene variants and inhibitor risk in African American hemophilia A patients
        
        
            
        
    
        
                
            
    
    
    
                    
        
        Activated protein C β-glycoform promotes enhanced noncanonical PAR1 proteolysis and superior resistance to ischemic injury
        
        
            
        
    
        
                
            
    
    
    
        
        
     
    
                     
    
                     
    
 
    
            
    
        
    
         
 
    
    
        
    
            
    
        
    
    
    
        
    
    
    
            
    
                    
 
    
    
 
    
    
        
    
    
    
            
        
 
    
    
 
    
    
        
    
    
    
            
        
            
    
        
        
    
             
            
             
            
             
        
    
 
    
    
 
    
    
        
    
    
    
            
    
                    
 
    
    
 
    
    
 
    
    
    
    
        
    Issue Archive
Table of Contents
INSIDE BLOOD COMMENTARIES
HOW I TREAT
CLINICAL TRIALS AND OBSERVATIONS
        
        Safety and activity of BTK inhibitor ibrutinib combined with ofatumumab in chronic lymphocytic leukemia: a phase 1b/2 study
        
        
            
        
                    
                        Clinical Trials & Observations
                    
        
            
    
        
            Samantha M. Jaglowski,Jeffrey A. Jones,Veena Nagar,Joseph M. Flynn,Leslie A. Andritsos,Kami J. Maddocks,Jennifer A. Woyach,Kristie A. Blum,Michael R. Grever,Kelly Smucker,Amy S. Ruppert,Nyla A. Heerema,Gerard Lozanski,Mona Stefanos,Brian Munneke,Jamie-Sue West,Jutta K. Neuenburg,Danelle F. James,Nathan Hall,Amy J. Johnson,John C. Byrd
            
        
    
            
        
        Critical analysis of the stringent complete response in multiple myeloma: contribution of sFLC and bone marrow clonality
        
        
            
        
                    
                        Clinical Trials & Observations
                    
                    
                        Brief Report
                    
        
            
    
        
            Joaquín Martínez-López,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,Bruno Paiva,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,Lucía López-Anglada,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,María-Victoria Mateos,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,Teresa Cedena,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,María-Belén Vidríales,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,María Auxiliadora Sáez-Gómez,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,Teresa Contreras,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,Albert Oriol,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,Inmaculada Rapado,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,Ana-Isabel Teruel,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,Lourdes Cordón,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,María Jesús Blanchard,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,Enrique Bengoechea,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,Luis Palomera,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,Felipe de Arriba,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,Cecilia Cueto-Felgueroso,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,Alberto Orfao,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,Joan Bladé,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,Jesús F. San Miguel,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group,Juan José Lahuerta,on behalf of the Grupo Español de Mieloma Múltiple/Programa para el Estudio de la Terapéutica en Hemopatías Malignas (GEM/PETHEMA) Cooperative Study Group
            
        
    
            LYMPHOID NEOPLASIA
PLATELETS AND THROMBOPOIESIS
RED CELLS, IRON, AND ERYTHROPOIESIS
THROMBOSIS AND HEMOSTASIS
        
        Factor VIII gene variants and inhibitor risk in African American hemophilia A patients
        
        
            
        
                    
                        Clinical Trials & Observations
                    
        
            
    
        
            Devi Gunasekera,on behalf of the Personalized Approaches to Therapies for Hemophilia (PATH) Study Investigators,Ruth A. Ettinger,on behalf of the Personalized Approaches to Therapies for Hemophilia (PATH) Study Investigators,Shelley Nakaya Fletcher,on behalf of the Personalized Approaches to Therapies for Hemophilia (PATH) Study Investigators,Eddie A. James,on behalf of the Personalized Approaches to Therapies for Hemophilia (PATH) Study Investigators,Maochang Liu,on behalf of the Personalized Approaches to Therapies for Hemophilia (PATH) Study Investigators,John C. Barrett,on behalf of the Personalized Approaches to Therapies for Hemophilia (PATH) Study Investigators,Janice Withycombe,on behalf of the Personalized Approaches to Therapies for Hemophilia (PATH) Study Investigators,Dana C. Matthews,on behalf of the Personalized Approaches to Therapies for Hemophilia (PATH) Study Investigators,Melinda S. Epstein,on behalf of the Personalized Approaches to Therapies for Hemophilia (PATH) Study Investigators,Richard J. Hughes,on behalf of the Personalized Approaches to Therapies for Hemophilia (PATH) Study Investigators,Kathleen P. Pratt,on behalf of the Personalized Approaches to Therapies for Hemophilia (PATH) Study Investigators
            
        
    
            
        
        Activated protein C β-glycoform promotes enhanced noncanonical PAR1 proteolysis and superior resistance to ischemic injury
        
        
            
        
                    
                        Brief Report
                    
        
            
    
        
            Eimear M. Gleeson,María G. Dichiara,Agustina Salicio,Louise M. Quinn,Clive Drakeford,Shane E. Russell,Patrick T. Walsh,Josune Orbe,José Hermida,Owen P. Smith,James S. O’Donnell,Ramón Montes,Roger J. S. Preston
            
        
    
            BLOOD WORK
CORRESPONDENCE
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            Cover Image
        
        Cover Image![issue cover]()  This case of Epstein-Barr virus–positive diffuse large B-cell lymphoma arose in a 27-year-old pregnant female. The neoplastic large lymphoid cells dissected through the skeletal muscle fibers of the chest wall (original magnification ×200; hematoxylin and eosin stain). Separately, the neoplastic cells were positive for CD79a, PAX5, MUM1, LMP1, and EBNA2 in Figure 3 (see the article by Nicolae et al on page 863). 
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