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Issue Archive

Volume 130, Issue 2
July 13 2017
Issue Cover

Table of Contents

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
The challenge of hospital-related thrombosis
Kenneth A. Bauer
View Articletitled, The challenge of hospital-related thrombosis
INSIDE BLOOD COMMENTARY
A molecular roadmap for midostaurin in mastocytosis
Clinical Trials & Observations
Jason Gotlib
View Articletitled, A molecular roadmap for midostaurin in mastocytosis
INSIDE BLOOD COMMENTARY
Targeting deubiquitinases in CLL
Deepa Sampath
View Articletitled, Targeting deubiquitinases in CLL
INSIDE BLOOD COMMENTARY
Soluble P-selectin is the smoke, not the fire
Peter L. Gross
View Articletitled, Soluble P-selectin is the smoke, not the fire
INSIDE BLOOD COMMENTARY
Factor V marks platelet-primed megakaryocytes
Alessandra Bertoni
View Articletitled, Factor V marks platelet-primed megakaryocytes
INSIDE BLOOD COMMENTARY
Myocardial fibrosis: the heart of diastole?
Jon A. Detterich
View Articletitled, Myocardial fibrosis: the heart of diastole?
INSIDE BLOOD COMMENTARY
Bruised platelet transfusions work
Thomas S. Kickler
View Articletitled, Bruised platelet transfusions work
INSIDE BLOOD COMMENTARY
Checking up on checkpoint inhibitors
Richard F. Little,Howard Streicher
View Articletitled, Checking up on checkpoint inhibitors

PLENARY PAPER

THROMBOSIS AND HEMOSTASIS
Effect of a near-universal hospitalization-based prophylaxis regimen on annual number of venous thromboembolism events in the US
Clinical Trials & Observations
John A. Heit,Daniel J. Crusan,Aneel A. Ashrani,Tanya M. Petterson,Kent R. Bailey
View Articletitled, Effect of a near-universal hospitalization-based prophylaxis regimen on annual number of venous thromboembolism events in the US
Supplemental data

PERSPECTIVE

JAK2 inhibitors for myeloproliferative neoplasms: what is next?
Clinical Trials & Observations
Prithviraj Bose,Srdan Verstovsek
View Articletitled, JAK2 inhibitors for myeloproliferative neoplasms: what is next?

HOW I TREAT

How I treat chronic myelomonocytic leukemia
Clinical Trials & Observations
Eric Solary,Raphael Itzykson
View Articletitled, How I treat chronic myelomonocytic leukemia

CLINICAL TRIALS AND OBSERVATIONS

Response and progression on midostaurin in advanced systemic mastocytosis: KIT D816V and other molecular markers
Clinical Trials & Observations
Mohamad Jawhar,Juliana Schwaab,Nicole Naumann,Hans-Peter Horny,Karl Sotlar,Torsten Haferlach,Georgia Metzgeroth,Alice Fabarius,Peter Valent,Wolf-Karsten Hofmann,Nicholas C. P. Cross,Manja Meggendorfer,Andreas Reiter
View Articletitled, Response and progression on midostaurin in advanced systemic mastocytosis: <em>KIT</em> D816V and other molecular markers

IMMUNOBIOLOGY

T cells lacking HDAC11 have increased effector functions and mediate enhanced alloreactivity in a murine model
David M. Woods,Karrune V. Woan,Fengdong Cheng,Andressa L. Sodré,Dapeng Wang,Yongxia Wu,Zi Wang,Jie Chen,John Powers,Javier Pinilla-Ibarz,Yu Yu,Ya Zhang,Xuefeng Wu,Xiaoyan Zheng,Jeffrey Weber,Wayne W. Hancock,Edward Seto,Alejandro Villagra,Xue-Zhong Yu,Eduardo M. Sotomayor
View Articletitled, T cells lacking HDAC11 have increased effector functions and mediate enhanced alloreactivity in a murine model
Supplemental data

LYMPHOID NEOPLASIA

USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status
Angelo Agathanggelou,Edward Smith,Nicholas J. Davies,Marwan Kwok,Anastasia Zlatanou,Ceri E. Oldreive,Jingwen Mao,David Da Costa,Sina Yadollahi,Tracey Perry,Pamela Kearns,Anna Skowronska,Elliot Yates,Helen Parry,Peter Hillmen,Celine Reverdy,Remi Delansorne,Shankara Paneesha,Guy Pratt,Paul Moss,A. Malcolm R. Taylor,Grant S. Stewart,Tatjana Stankovic
View Articletitled, USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status
Supplemental data

MYELOID NEOPLASIA

Hematopoietic origin of Langerhans cell histiocytosis and Erdheim-Chester disease in adults
Paul Milne,Venetia Bigley,Chris M. Bacon,Antoine Néel,Naomi McGovern,Simon Bomken,Muzlifah Haniffa,Eli L. Diamond,Benjamin H. Durham,Johannes Visser,David Hunt,Harsha Gunawardena,Mac Macheta,Kenneth L. McClain,Carl Allen,Omar Abdel-Wahab,Matthew Collin
View Articletitled, Hematopoietic origin of Langerhans cell histiocytosis and Erdheim-Chester disease in adults
Supplemental data
Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem/progenitor cells
Brief Report
Benjamin H. Durham,Damien Roos-Weil,Claude Baillou,Fleur Cohen-Aubart,Akihide Yoshimi,Makoto Miyara,Matthias Papo,Zofia Hélias-Rodzewicz,Nathalie Terrones,Neval Ozkaya,Ahmet Dogan,Raajit Rampal,Fanny Urbain,Lucie Le Fèvre,Eli L. Diamond,Christopher Y. Park,Thomas Papo,Frédéric Charlotte,Guy Gorochov,Valérie Taly,Olivier A. Bernard,Zahir Amoura,Omar Abdel-Wahab,François M. Lemoine,Julien Haroche,Jean-François Emile
View Articletitled, Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem/progenitor cells
Supplemental data

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

Circulating soluble P-selectin must dimerize to promote inflammation and coagulation in mice
Sumith R. Panicker,Padmaja Mehta-D’souza,Nan Zhang,Arkadiusz G. Klopocki,Bojing Shao,Rodger P. McEver
View Articletitled, Circulating soluble P-selectin must dimerize to promote inflammation and coagulation in mice
Supplemental data

PLATELETS AND THROMBOPOIESIS

Identifying and enriching platelet-producing human stem cell–derived megakaryocytes using factor V uptake
Xiuli Sim,Danuta Jarocha,Vincent Hayes,Hayley A. Hanby,Michael S. Marks,Rodney M. Camire,Deborah L. French,Mortimer Poncz,Paul Gadue
View Articletitled, Identifying and enriching platelet-producing human stem cell–derived megakaryocytes using factor V uptake
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Association between diffuse myocardial fibrosis and diastolic dysfunction in sickle cell anemia
Clinical Trials & Observations
Omar Niss,Robert Fleck,Fowe Makue,Tarek Alsaied,Payal Desai,Jeffrey A. Towbin,Punam Malik,Michael D. Taylor,Charles T. Quinn
View Articletitled, Association between diffuse myocardial fibrosis and diastolic dysfunction in sickle cell anemia
Supplemental data

TRANSFUSION MEDICINE

The effect of variation in donor platelet function on transfusion outcome: a semirandomized controlled trial
Clinical Trials & Observations
Anne M. Kelly,Stephen F. Garner,Theodora Foukaneli,Thomas R. Godec,Nina Herbert,Brennan C. Kahan,Alison Deary,Lekha Bakrania,Charlotte Llewelyn,Willem H. Ouwehand,Lorna M. Williamson,Rebecca A. Cardigan
View Articletitled, The effect of variation in donor platelet function on transfusion outcome: a semirandomized controlled trial
Supplemental data

TRANSPLANTATION

PD-1 blockade for relapsed lymphoma post–allogeneic hematopoietic cell transplant: high response rate but frequent GVHD
Clinical Trials & Observations
Bradley M. Haverkos,Diana Abbott,Mehdi Hamadani,Philippe Armand,Mary E. Flowers,Reid Merryman,Manali Kamdar,Abraham Sebastian Kanate,Ayman Saad,Amitkumar Mehta,Siddhartha Ganguly,Timothy S. Fenske,Parameswaran Hari,Robert Lowsky,Leslie Andritsos,Madan Jagasia,Asad Bashey,Stacey Brown,Veronika Bachanova,Deborah Stephens,Shin Mineishi,Ryotaro Nakamura,Yi-Bin Chen,Bruce R. Blazar,Jonathan Gutman,Steven M. Devine
View Articletitled, PD-1 blockade for relapsed lymphoma post–allogeneic hematopoietic cell transplant: high response rate but frequent GVHD
Supplemental data

BLOOD WORK

CART attack
Vinodh Pillai,Shannon L. Maude
View Articletitled, CART attack
Myeloid leukemia associated with Down syndrome
Caroline E. Talsma,Daniel F. Boyer
View Articletitled, Myeloid leukemia associated with Down syndrome
Diagnosing therapy-related acute myeloid leukemia with 8% blasts in bone marrow with concomitant plasma cell myeloma
Beenu Thakral,Tariq Muzzafar
View Articletitled, Diagnosing therapy-related acute myeloid leukemia with 8% blasts in bone marrow with concomitant plasma cell myeloma

ERRATA

Straus SE, Jaffe ES, Puck JM, et al. The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis. Blood. 2001;98(1):194-200.
View Articletitled, Straus SE, Jaffe ES, Puck JM, et al. The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis. <em>Blood.</em> 2001;98(1):194-200.
Fischer K, Al-Sawaf O, Fink A-M, et al. Venetoclax and obinutuzumab in chronic lymphocytic leukemia. Blood. 2017;129(19):2702-2705.
View Articletitled, Fischer K, Al-Sawaf O, Fink A-M, et al. Venetoclax and obinutuzumab in chronic lymphocytic leukemia. <em>Blood.</em> 2017;129(19):2702-2705.
Cannavò A, Valsecchi C, Garagiola I, et al. Nonneutralizing antibodies against factor VIII and risk of inhibitor development in severe hemophilia A. Blood. 2017;129(10):1245-1250.
View Articletitled, Cannavò A, Valsecchi C, Garagiola I, et al. Nonneutralizing antibodies against factor VIII and risk of inhibitor development in severe hemophilia A. <em>Blood.</em> 2017;129(10):1245-1250.
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