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Journal Articles

Outcome of Infants Treated on Total Therapy for Infants with Acute Lymphoblastic Leukemia I: Results from a Non-Randomized Multi-Center Study

Blood (2023) 142 (Supplement 1): 823.

https://doi.org/10.1182/blood-2023-177798

Published: 2023

Journal Articles

Genomic Integration of Adult and Pediatric Acute Myeloid Leukemia Reveals Age Dependent Risk Association

Maarten Fornerod, Deedra Nicolet, Krzysztof Mrózek, Jonathan E. Kolitz, William G. Blum, Joseph O. Moore, Robert James Mayer, Richard M. Stone, Geoffrey L. Uy, Wendy Stock, John C. Byrd, Ann-Kathrin Eisfeld, Tanja A. Gruber

Blood (2022) 140 (Supplement 1): 9165–9166.

https://doi.org/10.1182/blood-2022-160470

Published: 2022

Journal Articles

Proteomic Analysis Identifies Epigenetic Modifiers and Potential Negative Regulators of Leukemogenesis KMD6A and SETDB1 to be Induced Post In Vivo Decitabine Exposure in Pediatric AML

Jatinder K. Lamba, Xueyuan Cao, Huiyun Wu, Hiroto Inaba, Raul C. Ribeiro, Junmin Peng, Tanja A. Gruber, Jeffrey E. Rubnitz, Stanley B. Pounds

Blood (2022) 140 (Supplement 1): 6086–6087.

https://doi.org/10.1182/blood-2022-166671

Published: 2022

Journal Articles

NUTM1 -Rearranged Infant and Pediatric B Cell Precursor Acute Lymphoblastic Leukemia: A Good Prognostic Subtype Identified in a Collaborative International Study

Blood (2020) 136 (Supplement 1): 25–26.

https://doi.org/10.1182/blood-2020-139376

Published: 2020

Journal Articles

Non-Coding HOX Fusions in Pediatric Non-Down Syndrome Acute Megakaryoblastic Leukemia

Fabienne R.S. Adriaanse, MSc, Sadie M. Sakurada, B.A., Shondra M. Pruett-Miller, PhD, Ronald W. Stam, PhD, Michel C Zwaan, MD PhD, Tanja A. Gruber, MD PhD

Blood (2019) 134 (Supplement_1): 533.

https://doi.org/10.1182/blood-2019-127014

Published: 2019

Journal Articles

Comprehensive Genomic Profiling of Pediatric Therapy-Related Myeloid Neoplasms Identifies Mecom Dysregulation to be Associated with Poor Outcome

Jason R Schwartz, MD PhD, Jing Ma, PhD, Michael P Walsh, PhD, Xiaolong Chen, PhD, Tamara Lamprecht, BS, Jennifer Kamens, MD, Scott Newman, PhD, Jinghui Zhang, PhD, Tanja A. Gruber, MD PhD, Xiaotu Ma, Jeffery M. Klco, MD PhD

Blood (2019) 134 (Supplement_1): 1394.

https://doi.org/10.1182/blood-2019-128665

Published: 2019

Journal Articles

A 5-Gene Ara-C, Daunorubicin and Etoposide (ADE) Drug Response Score As a Prognostic Tool to Predict AML Treatment Outcome

Abdelrahman H. Elsayed, MSc, Huiyun Wu, PhD, Xueyuan Cao, PhD, Susana C. Raimondi, PhD, James R. Downing, MD, Raul Ribeiro, MD, Tanja A. Gruber, MD PhD, Rhonda E. Ries, MA, Soheil Meshinchi, MD PhD, Jeffrey Rubnitz, MD PhD, Stanley Pounds, PhD, Jatinder K Lamba, M.Sc., PhD

Blood (2019) 134 (Supplement_1): 1429.

https://doi.org/10.1182/blood-2019-128787

Published: 2019

Journal Articles

KMT2A-Rearranged Infant Acute Lymphoblastic Leukemia Cells Undergo ER-Stress-Induced Apoptosis Following Exposure to Proteasome Inhibitors

Wonil Kim, PhD, Cary S. Koss, BS, Tanja A. Gruber, MD PhD

Blood (2019) 134 (Supplement_1): 1283.

https://doi.org/10.1182/blood-2019-127699

Published: 2019

Journal Articles

Integrative Analysis of Pediatric Acute Leukemia Identifies Immature Subtypes That Span a T Lineage and Myeloid Continuum with Distinct Prognoses

Blood (2019) 134 (Supplement_1): 918.

https://doi.org/10.1182/blood-2019-127411

Published: 2019

Journal Articles

Pediatric LSC3 (pLSC3) Score Derived from DNMT3B-CD34-GPR56 As a Prognostic Tool to Predict AML Patient Outcome: Results from Two Independent Pediatric AML Cohorts

Abdelrahman H Elsayed, MSc, Huiyun Wu, PhD, Xueyuan Cao, PhD, Susana C. Raimondi, PhD, James R. Downing, MD, Raul Ribeiro, MD, Tanja A. Gruber, MD PhD, Jeffrey Rubnitz, MD PhD, Stanley Pounds, PhD, Jatinder K Lamba, PhD

Blood (2018) 132 (Supplement 1): 290.

https://doi.org/10.1182/blood-2018-99-116462

Published: 2018

Journal Articles

Prognostic impact of t(16;21)(p11;q22) and t(16;21)(q24;q22) in pediatric AML: a retrospective study by the I-BFM Study Group

Blood (2018) 132 (15): 1584–1592.

https://doi.org/10.1182/blood-2018-05-849059

Published: 2018

Includes: Supplemental data

Journal Articles

Targeted Deep Sequencing of GATA1 more Sensitively Identifies Transient Myeloproliferative Disorder in Neonates with Down Syndrome

Bianca F Goemans, MD PhD, Sanne Noort, MD MSc, Marjolein Blink, MD PhD, Ko van Wouwe, MD PhD, Gertjan J.L. Kaspers, MD PhD, Valerie de Haas, MD PhD, Wouter J.W. Kollen, MD PhD, Vincent van der Velden, PhD, Tanja A. Gruber, MD PhD, Michel Zwaan, MD PhD

Blood (2017) 130 (Supplement 1): 2919.

https://doi.org/10.1182/blood.V130.Suppl_1.2919.2919

Published: 2017

Journal Articles

Distinct Outcome Based on Fusion Transcript in t(16;21) Rearranged Pediatric AML, a Collaborative Retrospective Analysis By the I-BFM SG

Blood (2017) 130 (Supplement 1): 184.

https://doi.org/10.1182/blood.V130.Suppl_1.184.184

Published: 2017

Journal Articles

Activating Mutations Are Potent Pro-Leukemic Mediators in Murine MLL-MLLT3 Leukemia That Cause Distinct Transcriptional Profiles

Axel Hyrenius-Wittsten, MSc, Helena Sturesson, PhD, Michael P. Walsh, PhD, Jenny Hansson, PhD, Julhash U. Kazi, PhD, Mattias Pilheden, MSc, Stephanie Nance, Pankaj Gupta, Guangchun Song, PhD, Jinghui Zhang, PhD, Jing Ma, PhD, Tanja A. Gruber, MD PhD, James R. Downing, MD PhD, Anna K. Andersson, PhD

Blood (2016) 128 (22): 3918.

https://doi.org/10.1182/blood.V128.22.3918.3918

Published: 2016

Journal Articles

Prevalence of RNA Editing Events Affecting Coding Regions in Pediatric Leukemia

Ji Wen, PhD, Michael Rusch, Michael Edmonson, PhD, Charles Mullighan, MBBS, MSc, MD, Tanja A. Gruber, MD PhD, David W Ellison, MD, Jinghui Zhang, PhD

Blood (2016) 128 (22): 3928.

https://doi.org/10.1182/blood.V128.22.3928.3928

Published: 2016

Journal Articles

Genomic Profiling Identifies Novel Mutations and Fusion Genes in Newly Diagnosed and Relapsed Pediatric FLT3-ITD-Positive AML

Daelynn R Buelow, PhD, Stanley Pounds, PhD, Yong-Dong Wang, Lei Shi, PhD, Yongjin Li, PhD, David Finkelstein, Sheila A Shurtleff, PhD, Geoffrey A. Neale, PhD, Hiroto Inaba, MD PhD, Raul C. Ribeiro, MD, Dominique Garrison, Shelley Orwick, BS, James S. Blachly, MD, John C. Byrd, MD, Karl Kroll, Tanja A. Gruber, MD PhD, Jeffrey E Rubnitz, MD PhD, Sharyn D Baker, PharmD, PhD

Blood (2016) 128 (22): 2838.

https://doi.org/10.1182/blood.V128.22.2838.2838

Published: 2016

Journal Articles

Next Generation Sequencing Identifies a Novel Subset of Non-Down Syndrome Acute Megakaryoblastic Leukemia Characterized By Chimeric Transcripts Involving HOX Cluster Genes

Blood (2015) 126 (23): 171.

https://doi.org/10.1182/blood.V126.23.171.171

Published: 2015

Journal Articles

Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms

Benjamin Heath Durham, MD BS, Eli L. Diamond, MD, Julien Haroche, MD PhD, Zhan Yao, PhD, Jing Ma, PhD, Sameer A. Parikh, MD, John Choi, Eunhee Kim, PhD, Fleur Cohen-Aubart, Stanley Chun-Wei Lee, Yijun Gao, Jean-Baptiste Micol, MD, Patrick Campbell, MD PhD, Michael P. Walsh, Brooke Sylvester, Igor Dolgalev, Aminova Olga, Adriana Heguy, Paul Zappile, Joy Nakitandwe, BSc,MSc,PhD, James Dalton, BS, David W Ellison, MD, Juvianee Estrada-Veras, Mario Lacouture, William A. Gahl, MD PhD, Phil Stephens, PhD, Vincent A. Miller, MD, Jeffrey Ross, Siraj Ali, Sebastien Héritier, Jean Donadieu, MD PhD, David Solit, MD, David M. Hyman, Jose Baselga, MD PhD, Filip Janku, MDPhD, Barry S. Taylor, PhD, Christopher Y. Park, MD, PhD, Ahmet Dogan, MD PhD, Zahir Amoura, Jean-Francois Emile, Raajit K. Rampal, MD, PhD, Neal Rosen, MD PhD, Tanja A. Gruber, MD PhD, Omar Abdel-Wahab

Blood (2015) 126 (23): 481.

https://doi.org/10.1182/blood.V126.23.481.481

Published: 2015

Journal Articles

The biology of pediatric acute megakaryoblastic leukemia

Tanja A. Gruber, James R. Downing

Blood (2015) 126 (8): 943–949.

https://doi.org/10.1182/blood-2015-05-567859

Published: 2015

Journal Articles

Targeted Inhibition of the MLL Transcriptional Complex By Proteosome Inhibitors Elicits a High Response Rate in Relapsed/Refractory MLL Rearranged Leukemia

Cary Koss, BS, Stephanie Nance, PhD, Michele Connelly, MS, Jing Ma, PhD, Anang Shelat, PhD, Anitria Cotton, BS, Qi An, MS, Cheng Cheng, PhD, Monika L. Metzger, MD MS, Sima Jeha, MD, Jeffrey E Rubnitz, MD PhD, James R Downing, MD, R. Kiplin Guy, PhD, Tanja A Gruber, MD PhD

Blood (2014) 124 (21): 972.

https://doi.org/10.1182/blood.V124.21.972.972

Published: 2014

NARROW

Outcome of Infants Treated on Total Therapy for Infants with Acute Lymphoblastic Leukemia I: Results from a Non-Randomized Multi-Center Study

Genomic Integration of Adult and Pediatric Acute Myeloid Leukemia Reveals Age Dependent Risk Association

Proteomic Analysis Identifies Epigenetic Modifiers and Potential Negative Regulators of Leukemogenesis KMD6A and SETDB1 to be Induced Post In Vivo Decitabine Exposure in Pediatric AML

NUTM1 -Rearranged Infant and Pediatric B Cell Precursor Acute Lymphoblastic Leukemia: A Good Prognostic Subtype Identified in a Collaborative International Study

Non-Coding HOX Fusions in Pediatric Non-Down Syndrome Acute Megakaryoblastic Leukemia

Comprehensive Genomic Profiling of Pediatric Therapy-Related Myeloid Neoplasms Identifies Mecom Dysregulation to be Associated with Poor Outcome

A 5-Gene Ara-C, Daunorubicin and Etoposide (ADE) Drug Response Score As a Prognostic Tool to Predict AML Treatment Outcome

KMT2A-Rearranged Infant Acute Lymphoblastic Leukemia Cells Undergo ER-Stress-Induced Apoptosis Following Exposure to Proteasome Inhibitors

Integrative Analysis of Pediatric Acute Leukemia Identifies Immature Subtypes That Span a T Lineage and Myeloid Continuum with Distinct Prognoses

Pediatric LSC3 (pLSC3) Score Derived from DNMT3B-CD34-GPR56 As a Prognostic Tool to Predict AML Patient Outcome: Results from Two Independent Pediatric AML Cohorts

Prognostic impact of t(16;21)(p11;q22) and t(16;21)(q24;q22) in pediatric AML: a retrospective study by the I-BFM Study Group

Targeted Deep Sequencing of GATA1 more Sensitively Identifies Transient Myeloproliferative Disorder in Neonates with Down Syndrome

Distinct Outcome Based on Fusion Transcript in t(16;21) Rearranged Pediatric AML, a Collaborative Retrospective Analysis By the I-BFM SG

Activating Mutations Are Potent Pro-Leukemic Mediators in Murine MLL-MLLT3 Leukemia That Cause Distinct Transcriptional Profiles

Prevalence of RNA Editing Events Affecting Coding Regions in Pediatric Leukemia

Genomic Profiling Identifies Novel Mutations and Fusion Genes in Newly Diagnosed and Relapsed Pediatric FLT3-ITD-Positive AML

Next Generation Sequencing Identifies a Novel Subset of Non-Down Syndrome Acute Megakaryoblastic Leukemia Characterized By Chimeric Transcripts Involving HOX Cluster Genes

Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms

The biology of pediatric acute megakaryoblastic leukemia

Targeted Inhibition of the MLL Transcriptional Complex By Proteosome Inhibitors Elicits a High Response Rate in Relapsed/Refractory MLL Rearranged Leukemia

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American Society of Hematology

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American Society of Hematology

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