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Journal Articles

Platelet glycoprotein VI promotes metastasis through interaction with cancer cell–derived galectin-3

Elmina Mammadova-Bach, Jesus Gil-Pulido, Edita Sarukhanyan, Philipp Burkard, Sergey Shityakov, Charlotte Schonhart, David Stegner, Katharina Remer, Paquita Nurden, Alan T. Nurden, Thomas Dandekar, Laszlo Nehez, Magdolna Dank, Attila Braun, Diego Mezzano, Scott I. Abrams, Bernhard Nieswandt

Blood (2020) 135 (14): 1146–1160.

https://doi.org/10.1182/blood.2019002649

Published: 2020

Includes: Supplemental data

Journal Articles

A mutation of the human EPHB2 gene leads to a major platelet functional defect

Blood (2018) 132 (19): 2067–2077.

https://doi.org/10.1182/blood-2018-04-845644

Published: 2018

Includes: Supplemental data

Journal Articles

Phenotype Analysis and Clinical Management in a Large Family with a Novel Truncating Mutation in RASGRP2 , the Caldag-GEFI Encoding Gene

Amrita Desai, MD MPH, Wenche Jy, PhD, Wolfgang Bergmeier, PhD, Mathias Canault, PhD, Marie-Christine Alessi, MD PhD, Paquita Nurden, MD PhD, Yeon-Soong Ahn, MD, Alan T. Nurden, PhD

Blood (2016) 128 (22): 3713.

https://doi.org/10.1182/blood.V128.22.3713.3713

Published: 2016

Journal Articles

A gain-of-function variant in DIAPH1 causes dominant macrothrombocytopenia and hearing loss

Blood (2016) 127 (23): 2903–2914.

https://doi.org/10.1182/blood-2015-10-675629

Published: 2016

Includes: Supplemental data

Journal Articles

A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders

Ilenia Simeoni, Jonathan C. Stephens, Fengyuan Hu, Sri V. V. Deevi, Karyn Megy, Tadbir K. Bariana, Claire Lentaigne, Sol Schulman, Suthesh Sivapalaratnam, Minka J. A. Vries, Sarah K. Westbury, Daniel Greene, Sofia Papadia, Marie-Christine Alessi, Antony P. Attwood, Matthias Ballmaier, Gareth Baynam, Emilse Bermejo, Marta Bertoli, Paul F. Bray, Loredana Bury, Marco Cattaneo, Peter Collins, Louise C. Daugherty, Rémi Favier, Deborah L. French, Bruce Furie, Michael Gattens, Manuela Germeshausen, Cedric Ghevaert, Anne C. Goodeve, Jose A. Guerrero, Daniel J. Hampshire, Daniel P. Hart, Johan W. M. Heemskerk, Yvonne M. C. Henskens, Marian Hill, Nancy Hogg, Jennifer D. Jolley, Walter H. Kahr, Anne M. Kelly, Ron Kerr, Myrto Kostadima, Shinji Kunishima, Michele P. Lambert, Ri Liesner, José A. López, Rutendo P. Mapeta, Mary Mathias, Carolyn M. Millar, Amit Nathwani, Marguerite Neerman-Arbez, Alan T. Nurden, Paquita Nurden, Maha Othman, Kathelijne Peerlinck, David J. Perry, Pawan Poudel, Pieter Reitsma, Matthew T. Rondina, Peter A. Smethurst, William Stevenson, Artur Szkotak, Salih Tuna, Christel van Geet, Deborah Whitehorn, David A. Wilcox, Bin Zhang, Shoshana Revel-Vilk, Paolo Gresele, Daniel B. Bellissimo, Christopher J. Penkett, Michael A. Laffan, Andrew D. Mumford, Augusto Rendon, Keith Gomez, Kathleen Freson, Willem H. Ouwehand, Ernest Turro

Blood (2016) 127 (23): 2791–2803.

https://doi.org/10.1182/blood-2015-12-688267

Published: 2016

Includes: Supplemental data

Journal Articles

Glanzmann thrombasthenia: a review of ITGA2B and ITGB3 defects with emphasis on variants, phenotypic variability, and mouse models

Alan T. Nurden, Mathieu Fiore, Paquita Nurden, Xavier Pillois

Blood (2011) 118 (23): 5996–6005.

https://doi.org/10.1182/blood-2011-07-365635

Published: 2011

Includes: Supplemental data

Journal Articles

Defects in Filamin A (FLNa) in Women with X-Linked Filaminopathies: Abnormalities in Platelet Production and Platelet Function

Paquita Nurden, MD, PhD, Marijke Bryckaert, PhD, Eliane Berrou, PhD, Frédéric Adam, PhD, Jean-Marie Daniel Lamazière, PhD, Anne-Cécile Pons, PhD, Cyril Goizet, MD, PhD, William Vainchenker, MD, PhD, Alan T. Nurden, PhD, Najet Debili, PhD

Blood (2011) 118 (21): 1152.

https://doi.org/10.1182/blood.V118.21.1152.1152

Published: 2011

Journal Articles

NEW FINDINGS From the FRENCH COHORT of MYH9-RELATED DISORDERS: PHENOTYPE PECULIARITIES and GENOTYPE NOVELTIES on Behalf of the National French Reference Center on Inherited Platelet Disorders (CRPP)

Béatrice Saposnik, PhD, Sylvie Binard, Alan T. Nurden, PhD, Paquita Nurden, MD, PhD, Nicole Schlegel, MD, PhD

Blood (2011) 118 (21): 1155.

https://doi.org/10.1182/blood.V118.21.1155.1155

Published: 2011

Journal Articles

Abnormal Proplatelet Formation and Myosin Activation Status in Patients with MYH9-Related Syndrome

Yolande Chen, MD, Siham Boukour, PhD, Paquita Nurden, MD, PhD, Ababacar Seye, Olivier Bluteau, PhD, Alberta Palazzo, Yunhua Chang, PhD, Larissa Lordier, PhD, Remi Favier, MD, Nicole Schlegel, MD, PhD, Anne Galy, PharmD, PhD, Alan T. Nurden, PhD, Hana Raslova, PhD, William Vainchenker, MD, PhD, Najet Debili, PhD

Blood (2011) 118 (21): 4826.

https://doi.org/10.1182/blood.V118.21.4826.4826

Published: 2011

Journal Articles

De Novo Synthesis & Storage of Human Factor VIII In Platelets Reduces Bleeding In Canine Hemophilia A

Lily M. Du, MD, Helen W.G. Franck, BS, Elizabeth P. Merricks, PhD, Paquita Nurden, MD, Eric S. Jensen, DVM, Sandra L. Haberichter, PhD, Troy B. Hawkins, PhD, Paula M. Jacobi, BS, Juan Fang, MD, Timothy C. Nichols, MD, Sevasti B. Koukouritaki, PhD, Qizhen Shi, MD, PhD, Robert R. Montgomery, MD, Kenneth Cornetta, MD, Alan T. Nurden, PhD, David A. Wilcox, PhD

Blood (2010) 116 (21): 2198.

https://doi.org/10.1182/blood.V116.21.2198.2198

Published: 2010

Journal Articles

Antagonism of P2y12 Receptor Results in Severe Impairment of Serum Thromboxane Levels. Can We Manage Patients without Combination Therapy with Aspirin?

Kamala Bhavaraju, MS, Alexander Georgakis, Jianguo Jin, MD, Yoshiaki Tomiyama, MD, Alan T. Nurden, Paquita Nurden, Satya P. Kunapuli, Ph.D.

Blood (2009) 114 (22): 4013.

https://doi.org/10.1182/blood.V114.22.4013.4013

Published: 2009

Journal Articles

Apoptotic-Like Events in Bernard-Soulier Syndrome (BSS) Platelets.

Margaret L. Rand, Hong Wang, K.W. Annie Bang, Jerome M. Teitel, Victor S. Blanchette, Alan T. Nurden, John Freedman

Blood (2008) 112 (11): 1235.

https://doi.org/10.1182/blood.V112.11.1235.1235

Published: 2008

Journal Articles

Morphological Changes of Platelets from Patients with Von Willebrand Disease Types 2B and 3 Suggest That Von Willebrand Factor Intervenes in Platelet Formation from Megakaryocytes.

Paquita Nurden, Alan T Nurden, Jean-Max Pasquet, Jocelyne Enouf, Cécile Faurie-Bonnafous, Sylvia La Marca, Margherita Punzo, Luciano Baronciani, Augusto B. Federici

Blood (2008) 112 (11): 1238.

https://doi.org/10.1182/blood.V112.11.1238.1238

Published: 2008

Journal Articles

Regulation of An Acquired Inhibitor to the GPVI Platelet Collagen Receptor in a Patient with An Autoimmune Syndrome and Kidney Disease.

Paquita Nurden, Narendra Tandon, Hisao Takizawa, Xiaoqi Gong, Alice Conception, Delphine Morel, Pierre Merville, Sebastien Loya, Martine Jandrot-Perrus, Alan T. Nurden

Blood (2008) 112 (11): 3407.

https://doi.org/10.1182/blood.V112.11.3407.3407

Published: 2008

Journal Articles

High Mortality in Mice with Platelets Expressing Integrin αIIbβ3 Lockedin Its High Affinity State.

David A. Wilcox, PhD, Juan Fang, MD, Paula North, MD, PhD, Paquita Nurden, MD, Alan T. Nurden, PhD, Nathalie Valentin, PhD

Blood (2008) 112 (11): 1832.

https://doi.org/10.1182/blood.V112.11.1832.1832

Published: 2008

Journal Articles

Thrombus stability on the vessel wall

Alan T. Nurden

Blood (2008) 112 (1): 4–5.

https://doi.org/10.1182/blood-2008-03-145433

Published: 2008

Journal Articles

Normal Presence of Tissue Inhibitors of Matrix Metalloproteinases in Platelets of Patients with the Gray Platelet Syndrome Suggests a Novel Organization for These Secreted Proteins.

Julien Villeneuve, Anna Block, PhD, Caroline Le Bousse, PhD, Sebastien Lepreux, MD, Jean-Max Pasquet, PhD, Paquita Nurden, MD, PhD, Jean Ripoche, MD, Alan T. Nurden, PhD

Blood (2007) 110 (11): 2104.

https://doi.org/10.1182/blood.V110.11.2104.2104

Published: 2007

Journal Articles

Abnormal Large Platelets Are Associated Not Only with von Willebrand Disease (VWD) Type 2B (Including Type 2B/1 New York) but Also with Severe Type 3: A Potential Role for von Willebrand Factor (VWF) in Megakaryocytopoiesis.

Paquita Nurden, MD, PhD, Alan T. Nurden, PhD, Jocelyne Enouf, PhD, Silvia La Marca, Luciano Baronciani, Augusto B. Federici, MD, PhD

Blood (2007) 110 (11): 101.

https://doi.org/10.1182/blood.V110.11.101.101

Published: 2007

Journal Articles

ROCK and Rho(ll) in bone marrow

Alan T. Nurden

Blood (2007) 110 (1): 5–6.

https://doi.org/10.1182/blood-2007-04-084459

Published: 2007

Journal Articles

Heterogeneity in the Gray Platelet Syndrome: Variable Expression of the TREM Family Member, TLT-1, in Platelets of Patients of Two Unrelated Families.

Alan T. Nurden, PhD, Paquita Nurden, MD, PhD, Emilse Bermejo, Anthony V. Washington, PhD, Daniel W. McVicar, PhD

Blood (2006) 108 (11): 1101.

https://doi.org/10.1182/blood.V108.11.1101.1101

Published: 2006

NARROW

Platelet glycoprotein VI promotes metastasis through interaction with cancer cell–derived galectin-3

A mutation of the human EPHB2 gene leads to a major platelet functional defect

Phenotype Analysis and Clinical Management in a Large Family with a Novel Truncating Mutation in RASGRP2 , the Caldag-GEFI Encoding Gene

A gain-of-function variant in DIAPH1 causes dominant macrothrombocytopenia and hearing loss

A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders

Glanzmann thrombasthenia: a review of ITGA2B and ITGB3 defects with emphasis on variants, phenotypic variability, and mouse models

Defects in Filamin A (FLNa) in Women with X-Linked Filaminopathies: Abnormalities in Platelet Production and Platelet Function

NEW FINDINGS From the FRENCH COHORT of MYH9-RELATED DISORDERS: PHENOTYPE PECULIARITIES and GENOTYPE NOVELTIES on Behalf of the National French Reference Center on Inherited Platelet Disorders (CRPP)

Abnormal Proplatelet Formation and Myosin Activation Status in Patients with MYH9-Related Syndrome

De Novo Synthesis & Storage of Human Factor VIII In Platelets Reduces Bleeding In Canine Hemophilia A

Antagonism of P2y12 Receptor Results in Severe Impairment of Serum Thromboxane Levels. Can We Manage Patients without Combination Therapy with Aspirin?

Apoptotic-Like Events in Bernard-Soulier Syndrome (BSS) Platelets.

Morphological Changes of Platelets from Patients with Von Willebrand Disease Types 2B and 3 Suggest That Von Willebrand Factor Intervenes in Platelet Formation from Megakaryocytes.

Regulation of An Acquired Inhibitor to the GPVI Platelet Collagen Receptor in a Patient with An Autoimmune Syndrome and Kidney Disease.

High Mortality in Mice with Platelets Expressing Integrin αIIbβ3 Lockedin Its High Affinity State.

Thrombus stability on the vessel wall

Normal Presence of Tissue Inhibitors of Matrix Metalloproteinases in Platelets of Patients with the Gray Platelet Syndrome Suggests a Novel Organization for These Secreted Proteins.

Abnormal Large Platelets Are Associated Not Only with von Willebrand Disease (VWD) Type 2B (Including Type 2B/1 New York) but Also with Severe Type 3: A Potential Role for von Willebrand Factor (VWF) in Megakaryocytopoiesis.

ROCK and Rho(ll) in bone marrow

Heterogeneity in the Gray Platelet Syndrome: Variable Expression of the TREM Family Member, TLT-1, in Platelets of Patients of Two Unrelated Families.

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American Society of Hematology

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American Society of Hematology

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