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Journal Articles

Targeting cancer-associated fibroblasts in the bone marrow prevents resistance to CART-cell therapy in multiple myeloma

Blood (2022) 139 (26): 3708–3721.

https://doi.org/10.1182/blood.2021012811

Published: 2022

Includes: Supplemental data

Journal Articles

RNA-Seq Based Immunoglobulin Repertoire Analysis of Normal Plasma Cells Generated in an in Vitro B Cell Differentiation System

Renee C Tschumper, Collin A Osborne, MS, Pritha Chanana, MS, Jaime I Davila, PhD, Denise K Walters, PhD BSc, Dominique B Hoelzinger, PhD, Diane F Jelinek, PhD

Blood (2019) 134 (Supplement_1): 1051.

https://doi.org/10.1182/blood-2019-127327

Published: 2019

Journal Articles

Targeting Cancer Associated Fibroblasts in the Bone Marrow Prevents Resistance to Chimeric Antigen Receptor T Cell Therapy in Multiple Myeloma

Reona Sakemura, MD PhD, Michelle J. Cox, Michael J. Hansen, Mehrdad Hefazi, MD, Claudia Manriquez Roman, Kendall J. Schick, Erin E. Tapper, Paulina Roman Moreno, MD, Michael W. Ruff, MD, Denise K Walters, PhD BSc, Sameer A. Parikh, MD, Neil E. Kay, MD, Saad S. Kenderian, MD

Blood (2019) 134 (Supplement_1): 865.

https://doi.org/10.1182/blood-2019-123277

Published: 2019

Journal Articles

GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts

Blood (2019) 133 (7): 697–709.

https://doi.org/10.1182/blood-2018-10-881722

Published: 2019

Includes: Supplemental data

Journal Articles

GM-CSF Blockade during Chimeric Antigen Receptor T Cell Therapy Reduces Cytokine Release Syndrome and Neurotoxicity and May Enhance Their Effector Functions

Blood (2018) 132 (Supplement 1): 961.

https://doi.org/10.1182/blood-2018-99-111766

Published: 2018

Journal Articles

CRISPR-Mediated Loss of Immunoglobulin Heavy Chain in Multiple Myeloma Cell Line Results in Metabolic Pathway Alterations

Denise K Walters, PhD, Renee C Tschumper, Dominique B Hoelzinger, PhD, Sophia J Quinton, Xiaojian Shi, PhD, Haiwei Gu, PhD, Diane F Jelinek, PhD

Blood (2018) 132 (Supplement 1): 1885.

https://doi.org/10.1182/blood-2018-99-114943

Published: 2018

Journal Articles

Proteomic and Biological Analysis of Myeloma Cell Derived Extracellular Vesicles

Dominique B Hoelzinger, PhD, Sophia J Quinton, Denise K Walters, PhD, Renee C Tschumper, Diane F Jelinek, PhD

Blood (2018) 132 (Supplement 1): 5605.

https://doi.org/10.1182/blood-2018-99-116926

Published: 2018

Journal Articles

Reliability of Myeloma Model Systems: KP-6 Is a Novel Hyperdiploid Cell Line

Brooks A Benard, BS, Renee C. Tschumper, Denise K. Walters, PhD BSc, Kristi Stephenson, BS, Diane F. Jelinek, PhD, Jonathan J Keats, PhD

Blood (2016) 128 (22): 3279.

https://doi.org/10.1182/blood.V128.22.3279.3279

Published: 2016

Journal Articles

Responsiveness Of Cytogenetically Discrete Human Myeloma Cell Lines To Lenalidomide: Lack Of Correlation With Cereblon and Interferon Regulatory Factor 4 Expression Levels

Alexandra J Greenberg, Denise K Walters, PhD, Bonnie Kaye Arendt, Renee C. Tschumper, Shaji K. Kumar, MD, S. Vincent Rajkumar, MD, Diane F. Jelinek, PhD

Blood (2013) 122 (21): 1962.

https://doi.org/10.1182/blood.V122.21.1962.1962

Published: 2013

Journal Articles

Eosinophils in the Bone Marrow Microenvironment: Effects On Malignant Plasma Cell Biology.

Tina W. Wong, Denise K. Walters, PhD, Hirohito Kita, MD, Diane F. Jelinek, PhD

Blood (2012) 120 (21): 2917.

https://doi.org/10.1182/blood.V120.21.2917.2917

Published: 2012

Journal Articles

CD147 Is a Novel Regulator of Progression and Proliferation of Multiple Myeloma Plasma Cells

Bonnie K. Arendt, Denise K. Walters, PhD, Xiaosheng Wu, MD, Renee C. Tschumper, Paul M. Huddleston, M.D., Kimberly J. Henderson, Angela Dispenzieri, MD, Diane F. Jelinek, Ph.D.

Blood (2011) 118 (21): 470.

https://doi.org/10.1182/blood.V118.21.470.470

Published: 2011

Journal Articles

Evidence for Ongoing DNA Damage in Multiple Myeloma as Revealed by Constitutive Phosphorylation of H2AX.

Denise K. Walters, PhD, Renee C. Tschumper, Xiaosheng Wu, M.D., Kimberly J. Henderson, Angela Dispenzieri, M.D, Diane F. Jelinek, PhD

Blood (2009) 114 (22): 2817.

https://doi.org/10.1182/blood.V114.22.2817.2817

Published: 2009

Journal Articles

RNAi screening of the tyrosine kinome identifies therapeutic targets in acute myeloid leukemia

Jeffrey W. Tyner, Denise K. Walters, Stephanie G. Willis, Mary Luttropp, Jason Oost, Marc Loriaux, Heidi Erickson, Amie S. Corbin, Thomas O'Hare, Michael C. Heinrich, Michael W. Deininger, Brian J. Druker

Blood (2008) 111 (4): 2238–2245.

https://doi.org/10.1182/blood-2007-06-097253

Published: 2008

Includes: Supplemental data

Journal Articles

A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia

Ting-lei Gu, Thomas Mercher, Jeffrey W. Tyner, Valerie L. Goss, Denise K. Walters, Melanie G. Cornejo, Cynthia Reeves, Lana Popova, Kimberly Lee, Michael C. Heinrich, John Rush, Masanori Daibata, Isao Miyoshi, D. Gary Gilliland, Brian J. Druker, Roberto D. Polakiewicz

Blood (2007) 110 (1): 323–333.

https://doi.org/10.1182/blood-2006-10-052282

Published: 2007

Includes: Supplemental data

Journal Articles

Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia

Ting-Lei Gu, Valerie L. Goss, Cynthia Reeves, Lana Popova, Julie Nardone, Joan MacNeill, Denise K. Walters, Yi Wang, John Rush, Michael J. Comb, Brian J. Druker, Roberto D. Polakiewicz

Blood (2006) 108 (13): 4202–4204.

https://doi.org/10.1182/blood-2006-06-026666

Published: 2006

Includes: Supplemental data

Journal Articles

RNAi-induced down-regulation of FLT3 expression in AML cell lines increases sensitivity to MLN518

Denise K. Walters, Eric P. Stoffregen, Michael C. Heinrich, Michael W. Deininger, Brian J. Druker

Blood (2005) 105 (7): 2952–2954.

https://doi.org/10.1182/blood-2004-07-2758

Published: 2005

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Targeting cancer-associated fibroblasts in the bone marrow prevents resistance to CART-cell therapy in multiple myeloma

RNA-Seq Based Immunoglobulin Repertoire Analysis of Normal Plasma Cells Generated in an in Vitro B Cell Differentiation System

Targeting Cancer Associated Fibroblasts in the Bone Marrow Prevents Resistance to Chimeric Antigen Receptor T Cell Therapy in Multiple Myeloma

GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts

GM-CSF Blockade during Chimeric Antigen Receptor T Cell Therapy Reduces Cytokine Release Syndrome and Neurotoxicity and May Enhance Their Effector Functions

CRISPR-Mediated Loss of Immunoglobulin Heavy Chain in Multiple Myeloma Cell Line Results in Metabolic Pathway Alterations

Proteomic and Biological Analysis of Myeloma Cell Derived Extracellular Vesicles

Reliability of Myeloma Model Systems: KP-6 Is a Novel Hyperdiploid Cell Line

Responsiveness Of Cytogenetically Discrete Human Myeloma Cell Lines To Lenalidomide: Lack Of Correlation With Cereblon and Interferon Regulatory Factor 4 Expression Levels

Eosinophils in the Bone Marrow Microenvironment: Effects On Malignant Plasma Cell Biology.

CD147 Is a Novel Regulator of Progression and Proliferation of Multiple Myeloma Plasma Cells

Evidence for Ongoing DNA Damage in Multiple Myeloma as Revealed by Constitutive Phosphorylation of H2AX.

RNAi screening of the tyrosine kinome identifies therapeutic targets in acute myeloid leukemia

A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia

Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia

RNAi-induced down-regulation of FLT3 expression in AML cell lines increases sensitivity to MLN518

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