Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 41

Sort by

Sort Order Select

Journal Articles

MYC-dependent permissiveness of PI3K hyperactivation renders metabolic vulnerability in R/R b-ALL

Junzhe Song, Huimin Liu, Xiaotian Ji, Kai Liu, Shiqi Luo, Yalin Kang, Ran Ding, Lars Klemm, Jianping Jin, Huilin Huang, Yuanhui Mao, He Huang, Markus Müschen, Gang Xiao

Blood (2025) 146 (Supplement 1): 1475.

https://doi.org/10.1182/blood-2025-1475

Published: 2025

Journal Articles

Polyunsaturated fatty acids control lipid membrane dynamics and ferroptosis sensitivity in B-cell lymphoma

Etienne Leveille, Eden Bramson, Mark Robinson, Carolina Gomis Perez, Ojas Chahal, Thierry Bertomeu, Andrew Chatr-aryamontri, Shalin Kothari, Kallol Gupta, Erdem Karatekin, Gang Xiao, Graeme Lancaster, Andrew Murphy, Marcus Conrad, Markus Müschen

Blood (2025) 146 (Supplement 1): 5094.

https://doi.org/10.1182/blood-2025-5094

Published: 2025

Journal Articles

Targeted hyperactivation of oncogenic STAT5-signaling in acute lymphoblastic leukemia

Kohei Kume, Zhangliang Cheng, Jian Xin Lin, Liang Xu, Gang Xiao, Mark Robinson, Etienne Leveille, Eden Bramson, Kadriye Nehir Cosgun, Huimin Geng, Merja Heinäniemi, Thomas Graeber, Janis Abkowitz, Hongbo Chi, Warren Alexander, Roberto Chiarle, Warren Leonard, Markus Müschen

Blood (2025) 146 (Supplement 1): 433.

https://doi.org/10.1182/blood-2025-433

Published: 2025

Journal Articles

NAMPT in macrophages promotes multiple myeloma drug resistance through mitochondrial metabolic reprogramming and modulates immunosuppression via the SIRT1/STAT3/SPP1 axis.

Shunnan Yao, Gang Xiao, Xi Huang, Qiqi Shen, Haoguang Chen, Chunting Zhu, Shengchun Jin, Enfan Zhang, Zhen Cai

Blood (2025) 146 (Supplement 1): 5707.

https://doi.org/10.1182/blood-2025-5707

Published: 2025

Journal Articles

Super-enhancer-mediated regulation of CD38 inducibility in multiple myeloma via the MAF/TRIM47/RARα axis

Zhenfeng Dai, Yunlu Jia, Qiqi Shen, Haoguang Chen, Xinyuan Dai, Shengchun Jin, Enfan Zhang, Jianbiao Zhou, Gang Xiao, Wee-joo Chng, Zhen Cai

Blood (2025) 146 (Supplement 1): 2156.

https://doi.org/10.1182/blood-2025-2156

Published: 2025

Journal Articles

Metabolism-focused CRISPR screen in B cell tumor identifies sphingolipid metabolism promotes resistance to CAR-T cell therapy

Qiqi Zhang, Ying Shen, Ruirui Jing, Yiqi Li, Dawei Huo, He Huang, Gang Xiao

Blood (2025) 146 (Supplement 1): 2320.

https://doi.org/10.1182/blood-2025-2320

Published: 2025

Journal Articles

Modeling the Initiation and Progression of Human MLL -Rearranged Precursor B Cell Acute Lymphoblastic Leukemia in Mice

Blood (2024) 144 (Supplement 1): 2738.

https://doi.org/10.1182/blood-2024-199829

Published: 2024

Journal Articles

PTEN Counter Balances mTORC1 and PI3K Activities to Maintain Metabolic Homeostasis of B-ALL

Huimin Liu, Junzhe Song, Mark E Robinson, Gang Xiao, Markus Müschen

Blood (2023) 142 (Supplement 1): 2780.

https://doi.org/10.1182/blood-2023-184800

Published: 2023

Journal Articles

Repurposing GSK3B Small Molecule Inhibitors for Refractory Lymphoid Malignancies

Blood (2023) 142 (Supplement 1): 2818.

https://doi.org/10.1182/blood-2023-190522

Published: 2023

Journal Articles

Mitochondrial Isocitrate Dehydrogenase Inhibition Enhances CAR T-Cell Function By Restraining Antioxidant Metabolism and Histone Acetylation

Xiaohui Si, Mi Shao, Xinyi Teng, Yue Huang, Tianning Gu, Gang Xiao, He Huang

Blood (2023) 142 (Supplement 1): 3451.

https://doi.org/10.1182/blood-2023-187776

Published: 2023

Journal Articles

A Phosphatase Membrane-Shuttle Enables Feedback Control of B-Cell Signaling

Blood (2022) 140 (Supplement 1): 1698–1699.

https://doi.org/10.1182/blood-2022-170324

Published: 2022

Journal Articles

Phosphorylation Stabilized TET1 Acts As an Oncoprotein and Therapeutic Target in B-Cell Acute Lymphoblastic Leukemia

Blood (2022) 140 (Supplement 1): 998–1000.

https://doi.org/10.1182/blood-2022-165469

Published: 2022

Journal Articles

BCL6-Mediated Escape from Negative Selection Enables RAS-Driven B-Cell Transformation

Lai N. Chan, Christian Hurtz, Mark E. Robinson, Etienne Leveille, Huimin Geng, Rebecca Caeser, Liang Xu, Kohei Kume, Gang Xiao, Markus Müschen

Blood (2022) 140 (Supplement 1): 9177–9178.

https://doi.org/10.1182/blood-2022-169946

Published: 2022

Journal Articles

Targeting Unique Synthetic Lethal Interactions between PI3K and MYC in B-ALL

Gang Xiao, PhD, Kohei Kume, PhD, Huimin Geng, PhD, Than Than Han, MS, Lars Klemm, MS, Markus Müschen, MD PhD

Blood (2019) 134 (Supplement_1): 3785.

https://doi.org/10.1182/blood-2019-128719

Published: 2019

Journal Articles

Ifitm3 Is Essential for PI(3,4,5)P3-Dependent B-Cell Activation and Leukemogenesis

Jaewoong Lee, PhD, Gang Xiao, PhD, Kadriye Nehir Nehir Cosgun, PhD, Huimin Geng, PhD, Ning Ma, PhD, Lai N Chan, PhD, Kohei Kume, PhD, Matthew Nix, PhD, Zhengshan Chen, MD PhD, Chun-Wei David Chen, PhD, Jianjun Chen, PhD, Vishal Khairnar, PhD, Arun P. Wiita, MD PhD, Andrei Thomas-Tikhonenko, PhD, Michael Farzan, MD PhD, Michael S. Diamond, PhD, Jae U Jung, PhD, Nagarajan Vaidehi, PhD, Markus Müschen, MD PhD

Blood (2019) 134 (Supplement_1): 2782.

https://doi.org/10.1182/blood-2019-127615

Published: 2019

Journal Articles

Paraoxonase 2 Enables Initiation of B-ALL By Subverting Metabolic Gatekeeper Functions

Lili Pan, MD, Chao Hong, PhD, Gang Xiao, PhD, Huimin Geng, PhD, Shaoyuan Wang, MD, Markus Müschen, MD PhD

Blood (2019) 134 (Supplement_1): 746.

https://doi.org/10.1182/blood-2019-125171

Published: 2019

Journal Articles

Lgr5 Functions As a Critical Negative Regulator of Wnt/β-Catenin Signaling and Is Essential for B-Lymphopoiesis and Malignant B-Cell Transformation

Kadriye Nehir Cosgun, PhD, Gauri Deb, MS, PhD, Xin Yang, MD, Gang Xiao, PhD, Teresa Sadras, PhD, Jaewoong Lee, PhD, Lai N Chan, PhD, Kohei Kume, PhD, Lu Yang, PhD, Huimin Geng, PhD, John Chan, MD, Joo Y. Song, MD, Hassan Jumaa, PhD, Andrew G. Polson, PhD, Hans Clevers, MD PhD, Markus Müschen, MD PhD

Blood (2019) 134 (Supplement_1): 748.

https://doi.org/10.1182/blood-2019-127263

Published: 2019

Journal Articles

Rationale for Targeting BCL6 in MLL-Rearranged B-ALL

Lai N Chan, PhD, Christian Hurtz, PhD, Huimin Geng, PhD, Erica Ballabio, Gang Xiao, PhD, Gauri Deb, MS, PhD, Haytham Khoury, MD PhD, Scott A. Armstrong, MD PhD, Patricia Ernst, PhD, Ari Melnick, MD, Tom Arthur Milne, PhD, Markus Müschen, MD PhD

Blood (2019) 134 (Supplement_1): 1239.

https://doi.org/10.1182/blood-2019-131565

Published: 2019

Journal Articles

Dynamic Assembly of a Feedback Complex to Regulate Oncogenic B-Cell Receptor-Signaling

Blood (2019) 134 (Supplement_1): 393.

https://doi.org/10.1182/blood-2019-131270

Published: 2019

Journal Articles

Lgr5 Enables Positive B-Cell Selection and Tumor-Initiation in B-Cell Malignancies

Kadriye Nehir Cosgun, PhD, Gauri Deb, MS, PhD, Xin Yang, MD, Gang Xiao, PhD, Teresa Sadras, PhD, Franziska Auer, PhD, Jaewoong Lee, PhD, Anthony Abarientos, BSc, Maurizio Mangolini, PhD, Ali Aghajanirefah, PhD, Huimin Geng, PhD, Hassan Jumaa, PhD, Andrew G. Polson, PhD, Hans Clevers, MD PhD, Markus Muschen, MD

Blood (2018) 132 (Supplement 1): 547.

https://doi.org/10.1182/blood-2018-99-116956

Published: 2018

Update search

NARROW

Publications

Format

Article Type

Topics

Date

Availability

MYC-dependent permissiveness of PI3K hyperactivation renders metabolic vulnerability in R/R b-ALL

Polyunsaturated fatty acids control lipid membrane dynamics and ferroptosis sensitivity in B-cell lymphoma

Targeted hyperactivation of oncogenic STAT5-signaling in acute lymphoblastic leukemia

NAMPT in macrophages promotes multiple myeloma drug resistance through mitochondrial metabolic reprogramming and modulates immunosuppression via the SIRT1/STAT3/SPP1 axis.

Super-enhancer-mediated regulation of CD38 inducibility in multiple myeloma via the MAF/TRIM47/RARα axis

Metabolism-focused CRISPR screen in B cell tumor identifies sphingolipid metabolism promotes resistance to CAR-T cell therapy

Modeling the Initiation and Progression of Human MLL -Rearranged Precursor B Cell Acute Lymphoblastic Leukemia in Mice

PTEN Counter Balances mTORC1 and PI3K Activities to Maintain Metabolic Homeostasis of B-ALL

Repurposing GSK3B Small Molecule Inhibitors for Refractory Lymphoid Malignancies

Mitochondrial Isocitrate Dehydrogenase Inhibition Enhances CAR T-Cell Function By Restraining Antioxidant Metabolism and Histone Acetylation

A Phosphatase Membrane-Shuttle Enables Feedback Control of B-Cell Signaling

Phosphorylation Stabilized TET1 Acts As an Oncoprotein and Therapeutic Target in B-Cell Acute Lymphoblastic Leukemia

BCL6-Mediated Escape from Negative Selection Enables RAS-Driven B-Cell Transformation

Targeting Unique Synthetic Lethal Interactions between PI3K and MYC in B-ALL

Ifitm3 Is Essential for PI(3,4,5)P3-Dependent B-Cell Activation and Leukemogenesis

Paraoxonase 2 Enables Initiation of B-ALL By Subverting Metabolic Gatekeeper Functions

Lgr5 Functions As a Critical Negative Regulator of Wnt/β-Catenin Signaling and Is Essential for B-Lymphopoiesis and Malignant B-Cell Transformation

Rationale for Targeting BCL6 in MLL-Rearranged B-ALL

Dynamic Assembly of a Feedback Complex to Regulate Oncogenic B-Cell Receptor-Signaling

Lgr5 Enables Positive B-Cell Selection and Tumor-Initiation in B-Cell Malignancies

Email alerts

ASH Publications

American Society of Hematology

Update search

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only