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Julieta Abraham-Miranda
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Journal Articles

CAR-T efficacy in large B-cell lymphoma is shaped by neoantigen-driven epitope spreading and limited by HLA loss and genomic instability

Free
Constanza Savid-Frontera, Bachisio Ziccheddu, Venu Venkatarame Gowda Saralamma, Chandler Gatenbee, Meghan Menges, Luis Cuadrado Delgado, Monika Chojnacka, Kayla Reid, Julieta Abraham-Miranda, Anthony Augello, Austin Newsam, Abdessamad Youssfi Alaoui, Catalina Amador, Jay Spiegel, Juan Alderuccio, Mark Robertson-Tessi, Michael Jain, Alexander Anderson, Jonathan Schatz, Francesco Maura, Frederick Locke
Journal: Blood
Blood (2025) 146 (Supplement 1): 107.
https://doi.org/10.1182/blood-2025-107
Published: 2025
Journal Articles

Nfkb signaling in idecabtagene vicleucel infusion product drives response in relapsed/refractory multiple myeloma

Free
Jerald Noble, Barbara Peixoto, Meghan Menges, Julieta Abraham Miranda, Constanza Savid-Frontera, Salvatore Corallo, Emily Merritt, Gabriel De Avila, Omar Alexis Castaneda Puglianini, Hien Liu, Melissa Alsina, Taiga Nishihori, Kenneth Shain, Ariosto Siqueira Silva, Rachid Baz, Brandon Blue, Ariel Grajales-Cruz, Doris Hansen, John Cleveland, Fabiana Perna, Conor Lynch, Jennifer Binning, Reginald Atkins, Frederick Locke, Ciara Louise Freeman
Journal: Blood
Blood (2025) 146 (Supplement 1): 504.
https://doi.org/10.1182/blood-2025-504
Published: 2025
Journal Articles

Optimizing immunity to pneumococcus by vaccination with pneumococcal 13-valent conjugate vaccine before and after CD19-targeted CAR T cell immunotherapy

Free
M Bakri Hammami, Dasom (Caroline) Lee, Lindsey Raymond, Meghan Menges, Salvatore Corallo, Julieta Abraham Miranda, Bijal Shah, Julio Chavez, Aleksandr Lazaryan, Michael Jain, Frederick Locke
Journal: Blood
Blood (2025) 146 (Supplement 1): 4166.
https://doi.org/10.1182/blood-2025-4166
Published: 2025
Journal Articles

Tumor burden quantified by soluble B-cell maturation antigen and metabolic tumor volume determines myeloma CAR-T outcomes

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Ciara L. Freeman, Jerald Noble, Meghan Menges, Ricardo Villanueva, Justyn Y. Nakashima, Nicholas B. Figura, Rolf Petter Tonseth, Dietrich Werner Idiaquez, Lawrence Skelson, Eric Smith, Julieta Abraham-Miranda, Salvatore Corallo, Gabriel De Avila, Omar A. Castaneda Puglianini, Hien Liu, Melissa Alsina, Taiga Nishihori, Kenneth H. Shain, Rachid Baz, Brandon Blue, Ariel Grajales-Cruz, John M. Koomen, Reginald M. Atkins, Doris K. Hansen, Ariosto S. Silva, Jongphil Kim, Yoganand Balagurunathan, Frederick L. Locke
Journal: Blood
Blood (2025) 145 (15): 1645–1657.
https://doi.org/10.1182/blood.2024024965
Published: 2025
Includes: Supplemental data
Journal Articles

Single-Cell Analysis of CAR-T Cell Products Idecabtagene Vicleucel and Ciltacabtagene Autoleucel Reveals Factors That Influence Clinical Outcomes

Free
Jerald Noble, Xiaofei Song, Meghan Menges, Julieta Abraham-Miranda, Salvatore Corallo, Gabriel De Avila, Omar Puglianini, Hien Liu, Melissa Alsina, Taiga Nishihori, Kenneth H. Shain, Rachid Baz, Brandon Blue, Ariel Grajales-Cruz, Doris K. Hansen, Reginald Atkins, Frederick L. Locke, Ciara Louise Freeman
Journal: Blood
Blood (2024) 144 (Supplement 1): 7173.
https://doi.org/10.1182/blood-2024-208709
Published: 2024
Journal Articles

Comprehensive Analysis of Pre-Treatment Biomarkers Associated with Toxicity and Durable Responses in Idecabtagene Vicleucel Therapy for Relapsed/Refractory Multiple Myeloma

Free
Doris K. Hansen, Ciara Louise Freeman, Meghan Menges, Brett Reid, Julieta Abraham-Miranda, Kayla Reid, Luis Cuadrado Delgado, Gabriel De Avila, Laura B. Oswald, Ariel F. Grajales-Cruz, Brandon Blue, Rebecca Gonzalez, Salvatore Corallo, David R. Noyes, Mark B. Meads, Hien Liu, Taiga Nishihori, Kenneth H. Shain, Rachid Baz, Melissa Alsina, Omar Castaneda, Frederick L. Locke, Lauren C. Peres
Journal: Blood
Blood (2024) 144 (Supplement 1): 896.
https://doi.org/10.1182/blood-2024-197929
Published: 2024
Journal Articles

CD19 Intron Retention Is Mechanism of CAR-T Treatment Resistance in Non-Hodgkin Lymphoma

Free
Jerald Noble, Frederick L. Locke, Constanza Savid-Frontera, Michael D. Jain, Joel G. Turner, Julieta Abraham Miranda, Thushara W Madanayake, Samira Naderinezhad, Salvatore Corallo, Meghan Menges, Kayla Reid, Timothy J Robinson
Journal: Blood
Blood (2023) 142 (Supplement 1): 3506.
https://doi.org/10.1182/blood-2023-185074
Published: 2023
Journal Articles

Facility-Related Healthcare Resource Utilization (HCRU) for Patients Treated with Idecabtagene Vicleucel (Ide-Cel, bb2121) in a Real-World (RW) Setting: A Single-Center Experience

Free
Lauren C. Peres, Pallavi Patwardhan, David Huggar, Gabriel De Avila, Laura B. Oswald, Ariel F. Grajales-Cruz, Brandon Blue, Julieta Abraham Miranda, Kayla Reid, Hien Liu, Taiga Nishihori, Kenneth H. Shain, Rachid Baz, Melissa Alsina, Omar Castaneda, Frederick L. Locke, Ciara Louise L. Freeman, Simrandeep Tiwana, Afraim Botros, Doris K. Hansen
Journal: Blood
Blood (2023) 142 (Supplement 1): 5081.
https://doi.org/10.1182/blood-2023-173812
Published: 2023
Journal Articles

Clinical Impact of Neoantigen Burden and HLA Loss in Aggressive B-Cell Lymphomas Treated with CD19 CAR T-Cell

Free
Bachisio Ziccheddu, Michael D. Jain, Monika Chojnacka, Michael Durante, Julieta Abraham Miranda, Meghan Menges, Ola Landgren, Marco Davila, Jonathan H. Schatz, Francesco Maura, Frederick L. Locke
Journal: Blood
Blood (2023) 142 (Supplement 1): 4362.
https://doi.org/10.1182/blood-2023-182821
Published: 2023
Journal Articles

Paired Analysis from Patients with Myeloma Elucidates Favorable CAR-T Manufacture and Phenotype, Starting from Mobilized Pre-Transplant Apheresis Vs. Non-Mobilized Apheresis after Four Prior Lines

Free
Ciara Louise L. Freeman, Julieta Abraham Miranda, Meghan Menges, Jerald Noble, Hien Liu, Salvatore Corallo, Albert J Ribickas, Constanza Savid-Frontera, Gabriel De Avila, Omar Castaneda, Jose L. Ochoa-Bayona, Rachid Baz, Doris K. Hansen, Melissa Alsina, Kenneth H. Shain, Taiga Nishihori, Reginald Atkins, Frederick L. Locke
Journal: Blood
Blood (2023) 142 (Supplement 1): 1931.
https://doi.org/10.1182/blood-2023-187539
Published: 2023
Journal Articles

CAR-T Phenotype and Efficacy Is Impaired By Lymphoma-Associated CD39 + T Cells

Free
Michael D. Jain, Xiaoqing Yu, Reginald Atkins, Joel G. Turner, Jerald Noble, Meghan Menges, Kayla Reid, Salvatore Corallo, Ling Cen, Sean J. Yoder, Julieta Abraham Miranda, Samira Naderinezhad, Hien Liu, Bijal D. Shah, Julio C Chavez, Erin Dean, Johannes Fahrmann, Neeraj Y. Saini, Samir Hanash, Rebecca S. Hesterberg, Paulo C. Rodriguez, John L. Cleveland, Marco Davila, Xuefeng Wang, Frederick L. Locke
Journal: Blood
Blood (2023) 142 (Supplement 1): 3500.
https://doi.org/10.1182/blood-2023-178113
Published: 2023
Journal Articles

A Pro-Inflammatory State and Peak Cytokines Are Associated with Toxicity and Early Responses in Real-World Multiple Myeloma Patients Treated with Idecabtagene Vicleucel

Free
Doris K. Hansen, Lauren C. Peres, Julieta Abraham Miranda, Kayla Reid, Gabriel De Avila, David Huggar, Pallavi Patwardhan, Laura B. Oswald, Ariel F. Grajales-Cruz, Brandon Blue, Hien Liu, Taiga Nishihori, Kenneth Shain, Rachid Baz, Melissa Alsina, Omar Castaneda, Simran K. Tiwana, Afraim Botros, Frederick L. Locke, Ciara Louise L. Freeman
Journal: Blood
Blood (2023) 142 (Supplement 1): 1004.
https://doi.org/10.1182/blood-2023-174506
Published: 2023