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Journal Articles

Prothrombotic Antibodies Targeting the Spike Protein's Receptor-Binding Domain in Severe COVID-19

Blood blood.2024025010.

https://doi.org/10.1182/blood.2024025010

Published: 2024

Includes: Supplemental data

Journal Articles

A prospective, blinded study of a PF4-dependent assay for HIT diagnosis

Bethany Samuelson Bannow, Deepti M. Warad, Curtis G. Jones, Shannon M. Pechauer, Brian R. Curtis, Daniel W. Bougie, Ruchika Sharma, Diane E. Grill, Mary W. Redman, Parisa R. Khalighi, Rachel R. Leger, Rajiv K. Pruthi, Dong Chen, Daniel E. Sabath, Richard H. Aster, David A. Garcia, Anand Padmanabhan

Blood (2021) 137 (8): 1082–1089.

https://doi.org/10.1182/blood.2020008195

Published: 2021

Includes: Supplemental data

Journal Articles

Polyreactivity and Somatic Hypermutation Analysis Reveals the Innate B Cell Origin of Human PF4/Heparin Reactive Antibodies

Wen Zhu, MBBS,MS, Lu Zhou, Ting Zhao, Yongwei Zheng, PhD, Mei Yu, PhD, Jianhui Wei, Anand Padmanabhan, M.B.B.S., PhD, Richard H. Aster, MD, Demin Wang, PhD, Renren Wen, PhD

Blood (2020) 136 (Supplement 1): 34–35.

https://doi.org/10.1182/blood-2020-138781

Published: 2020

Journal Articles

Bioengineered iPSC-derived megakaryocytes for the detection of platelet-specific patient alloantibodies

Nanyan Zhang, Sentot Santoso, Richard H. Aster, Brian R. Curtis, Peter J. Newman

Blood (2019) 134 (22): e1–e8.

https://doi.org/10.1182/blood.2019002225

Published: 2019

Includes: Supplemental data

Journal Articles

Antibody Cloning Identifies Pathogenic and Non-Pathogenic Antibodies in Heparin-Induced Thrombocytopenia and Defines the Molecular Signatures That Differentiate the Two Types of Antibodies

Wen Zhu, Yongwei Zheng, PhD, Mei Yu, PhD, Yaling Wu, Jianhui Wei, Nicholas Schneider, Anand Padmanabhan, MD PhD, Richard H. Aster, MD, Demin Wang, PhD, Renren Wen, PhD

Blood (2019) 134 (Supplement_1): 439.

https://doi.org/10.1182/blood-2019-126097

Published: 2019

Journal Articles

Cross-Reactivity of Drug-Dependent Antibodies in Patients with Immune Thrombocytopenia Induced By Beta-Lactam Antibiotics

Matthew John Slaught, BS, Daniel W. Bougie, PhD, Richard H. Aster, MD

Blood (2019) 134 (Supplement_1): 2350.

https://doi.org/10.1182/blood-2019-131375

Published: 2019

Journal Articles

Cross-Strain Platelet Immunization in Selected Mouse Strains Recapitulates Clinical and Serologic Findings Typical of Post-Transfusion Purpura (PTP)

Daniel W. Bougie, PhD, Jessica Sutton, Richard H. Aster, MD

Blood (2019) 134 (Supplement_1): 2349.

https://doi.org/10.1182/blood-2019-126815

Published: 2019

Journal Articles

Serologic Characterization of Antibodies in Patients Experiencing Piperacillin-Induced Immune Thrombocytopenia

Mark Rasmussen, Daniel W. Bougie, PhD, Gregory H. Denomme, Richard H. Aster, MD

Blood (2019) 134 (Supplement_1): 1078.

https://doi.org/10.1182/blood-2019-130966

Published: 2019

Journal Articles

New Monoclonal Antibodies Reveal Distinct Specificities for Platelet Factor 4 Bound to Heparin Vs. Platelets: Implications for HIT Pathogenesis

Anand Padmanabhan, MD PhD, Shannon Pechauer, Curtis Jones, BS, Daniel Bougie, PhD, Richard H. Aster, MD

Blood (2019) 134 (Supplement_1): 1144.

https://doi.org/10.1182/blood-2019-127169

Published: 2019

Journal Articles

The First Case Report of Tazobactam Induced Thrombocytopenia

Minh-Tri H. Nguyen, MD, Pavneet Kaur, MD, Richard H. Aster, MD, Vidya Krishnan, MD MHS

Blood (2019) 134 (Supplement_1): 4897.

https://doi.org/10.1182/blood-2019-126227

Published: 2019

Journal Articles

Regulatory T Cells Control PF4/Heparin Antibody Production in Mice

Yongwei Zheng, Wen Zhu, Dipica Haribhai, PhD, Calvin B. Williams, PhD, Richard H. Aster, MD, Renren Wen, PhD, Demin Wang, PhD

Blood (2018) 132 (Supplement 1): 2542.

https://doi.org/10.1182/blood-2018-99-113049

Published: 2018

Journal Articles

Use of Intravenous Immunoglobulin G in HIT: Impact on Thrombosis and Mortality in a Population-Based Study

Binod Dhakal, MBBS, Rein Lisa, Aniko Szabo, PhD, Richard H. Aster, MD, Anand Padmanabhan, MD PhD

Blood (2018) 132 (Supplement 1): 2512.

https://doi.org/10.1182/blood-2018-99-117190

Published: 2018

Journal Articles

The Platelet Factor-4 (PF4)-Dependent p-Selectin Expression Assay (PEA) Is Highly Accurate for the Detection of Pathogenic HIT Antibodies: Results of a 440-Sample Prospective Blinded Study

Deepti M. Warad, MD, Bethany T Samuelson Bannow, MD, Curtis Jones, BS, Shannon Pechauer, Brian R. Curtis, PhD, Daniel W. Bougie, PhD, Parisa R Khalighi, BS, Diane E. Grill, MS, Rachel Leger, BAE, Ruchika Sharma, MD, Dong Chen, MD PhD, Richard H. Aster, MD, David A. Garcia, MD, Anand Padmanabhan, MD PhD

Blood (2018) 132 (Supplement 1): 416.

https://doi.org/10.1182/blood-2018-99-112475

Published: 2018

Journal Articles

Patients treated with oxaliplatin are at risk for thrombocytopenia caused by multiple drug-dependent antibodies

Brian R. Curtis, Yen-Michael S. Hsu, Nikolai Podoltsev, Jill Lacy, Susanna Curtis, Michael S. Samuel, Kristin Zutavern, Robert A. DeSimone, Daniel W. Bougie, Richard H. Aster

Blood (2018) 131 (13): 1486–1489.

https://doi.org/10.1182/blood-2017-10-812461

Published: 2018

Includes: Supplemental data

Journal Articles

Normal plasma IgG inhibits HIT antibody–mediated platelet activation: implications for therapeutic plasma exchange

Curtis G. Jones, Shannon M. Pechauer, Brian R. Curtis, Daniel W. Bougie, Richard H. Aster, Anand Padmanabhan

Blood (2018) 131 (6): 703–706.

https://doi.org/10.1182/blood-2017-08-803031

Published: 2018

Includes: Supplemental data

Journal Articles

Immunoglobulin G in Normal Plasma Inhibits HIT Antibody-Mediated Platelet Activation: Implications for Therapeutic Plasma Exchange Treatment in HIT

Curtis Jones, BS, Shannon Pechauer, Brian R. Curtis, PhDMT(ASCP), Daniel W. Bougie, PhD, Richard H. Aster, MD, Anand Padmanabhan, MD PhD

Blood (2017) 130 (Supplement 1): 2402.

https://doi.org/10.1182/blood.V130.Suppl_1.2402.2402

Published: 2017

Journal Articles

Drug-Induced Immune Thrombocytopenia (DITP) Caused By Multiple Drug-Dependent Platelet-Reactive Antibodies (DDAbs) in Patients Undergoing Oxaliplatin-Containing Combination Chemotherapy for Metastatic Colon Cancer

Brian R. Curtis, PhDMT(ASCP), Yen-Michael S. Hsu, MD PhD, Nikolai A. Podoltsev, MD PhD, Jill Lacy, MD, Susanna A Curtis, MD, Robert Andrew Desimone, MD, Michael Samuel, MD, Kristin Zutavern, BS, Daniel Bougie, PhD, Richard H. Aster, MD

Blood (2017) 130 (Supplement 1): 3625.

https://doi.org/10.1182/blood.V130.Suppl_1.3625.3625

Published: 2017

Journal Articles

A New Assay for Platelet-Activating HIT Antibodies, the PEA, Is Specific, Reproducible and Relatively Independent of the Choice of Platelet Donor

Shannon Pechauer, Curtis Jones, BS, Daniel W. Bougie, PhD, Brian R. Curtis, PhDMT(ASCP), Richard H. Aster, MD, Anand Padmanabhan, MD PhD

Blood (2017) 130 (Supplement 1): 458.

https://doi.org/10.1182/blood.V130.Suppl_1.458.458

Published: 2017

Journal Articles

Autoimmune Thrombocytopenia in Mice Immunized with Allogeneic Platelets: A Model for Post-Transfusion Purpura (PTP)?

Daniel W. Bougie, PhD, Jessica Sutton, Richard H. Aster, MD

Blood (2016) 128 (22): 168.

https://doi.org/10.1182/blood.V128.22.168.168

Published: 2016

Journal Articles

A Novel PF4-Dependent P-Selectin Expression Assay (PEA) Facilitates Early Detection of Pathogenic HIT Antibodies: Implications for Diagnosis and Treatment of HIT

Anand Padmanabhan, MBBS, MA, PhD, Curtis G Jones, Shannon M Pechauer, Brian R Curtis, PhD D(ABMLI) MT(ASCP)SBB, Daniel W. Bougie, PhD, Mia J Sullivan, Mehraboon S. Irani, MBBChir, Binod Dhakal, MDMS, Lisa M. Baumann Kreuziger, MD MS, Brenda M. Pierce, MD, Richard H. Aster, MD

Blood (2016) 128 (22): 2599.

https://doi.org/10.1182/blood.V128.22.2599.2599

Published: 2016

NARROW

Prothrombotic Antibodies Targeting the Spike Protein's Receptor-Binding Domain in Severe COVID-19

A prospective, blinded study of a PF4-dependent assay for HIT diagnosis

Polyreactivity and Somatic Hypermutation Analysis Reveals the Innate B Cell Origin of Human PF4/Heparin Reactive Antibodies

Bioengineered iPSC-derived megakaryocytes for the detection of platelet-specific patient alloantibodies

Antibody Cloning Identifies Pathogenic and Non-Pathogenic Antibodies in Heparin-Induced Thrombocytopenia and Defines the Molecular Signatures That Differentiate the Two Types of Antibodies

Cross-Reactivity of Drug-Dependent Antibodies in Patients with Immune Thrombocytopenia Induced By Beta-Lactam Antibiotics

Cross-Strain Platelet Immunization in Selected Mouse Strains Recapitulates Clinical and Serologic Findings Typical of Post-Transfusion Purpura (PTP)

Serologic Characterization of Antibodies in Patients Experiencing Piperacillin-Induced Immune Thrombocytopenia

New Monoclonal Antibodies Reveal Distinct Specificities for Platelet Factor 4 Bound to Heparin Vs. Platelets: Implications for HIT Pathogenesis

The First Case Report of Tazobactam Induced Thrombocytopenia

Regulatory T Cells Control PF4/Heparin Antibody Production in Mice

Use of Intravenous Immunoglobulin G in HIT: Impact on Thrombosis and Mortality in a Population-Based Study

The Platelet Factor-4 (PF4)-Dependent p-Selectin Expression Assay (PEA) Is Highly Accurate for the Detection of Pathogenic HIT Antibodies: Results of a 440-Sample Prospective Blinded Study

Patients treated with oxaliplatin are at risk for thrombocytopenia caused by multiple drug-dependent antibodies

Normal plasma IgG inhibits HIT antibody–mediated platelet activation: implications for therapeutic plasma exchange

Immunoglobulin G in Normal Plasma Inhibits HIT Antibody-Mediated Platelet Activation: Implications for Therapeutic Plasma Exchange Treatment in HIT

Drug-Induced Immune Thrombocytopenia (DITP) Caused By Multiple Drug-Dependent Platelet-Reactive Antibodies (DDAbs) in Patients Undergoing Oxaliplatin-Containing Combination Chemotherapy for Metastatic Colon Cancer

A New Assay for Platelet-Activating HIT Antibodies, the PEA, Is Specific, Reproducible and Relatively Independent of the Choice of Platelet Donor

Autoimmune Thrombocytopenia in Mice Immunized with Allogeneic Platelets: A Model for Post-Transfusion Purpura (PTP)?

A Novel PF4-Dependent P-Selectin Expression Assay (PEA) Facilitates Early Detection of Pathogenic HIT Antibodies: Implications for Diagnosis and Treatment of HIT

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American Society of Hematology

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ASH Publications

American Society of Hematology

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