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Daniel J Deangelo
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Journal Articles

Asciminib plus dasatinib and prednisone for Philadelphia chromosome-positive acute leukemia

Clinical Trials & Observations
Marlise R. Luskin, Mark Alan Murakami, Julia H. Keating, Yael Flamand, Eric S Winer, Jacqueline S. Garcia, Maximilian Stahl, Richard M. Stone, Martha Wadleigh, Stella Louise Jaeckle, Ella Hagopian, David M. Weinstock, Jessica Liegel, Malgorzata McMasters, Eunice S Wang, Wendy Stock, Daniel J DeAngelo
Journal: Blood
Blood blood.2024025800.
https://doi.org/10.1182/blood.2024025800
Published: 2024
Includes: Supplemental data
Journal Articles

A Meta-Analysis Comparing the Relative Efficacy of Pediatric-Inspired Regimens Versus Hyper-CVAD for the Treatment of Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma in Adolescents, Young Adults, and Adults

Wenqing Su, Melisa Stricherz, Alison Martin, Jonathan Belsey, Eric Kemadjou, Daniel J. DeAngelo
Journal: Blood
Blood (2023) 142 (Supplement 1): 3779.
https://doi.org/10.1182/blood-2023-173750
Published: 2023
Journal Articles

Blinatumomab in Combination with Immune Checkpoint Inhibitors (ICIs) of PD-1 and CTLA-4 in Adult Patients with Relapsed/Refractory (R/R) CD19 Positive B-Cell Acute Lymphoblastic Leukemia (ALL): Results of a Phase I Study

Jonathan Allen Webster, Marlise R. Luskin, Joseph Rimando, Amanda Blackford, Amer M. Zeidan, Elad Sharon, Howard Streicher, Daniel J. DeAngelo, Leo Luznik, Ivana Gojo
Journal: Blood
Blood (2023) 142 (Supplement 1): 966.
https://doi.org/10.1182/blood-2023-191109
Published: 2023
Journal Articles

What Is the Optimal Treatment Modality in Molecularly Defined Secondary AML? a Multicenter Cohort Study

Shai Shimony, Jan Philipp Bewersdorf, Rory M. Shallis, Yiwen Liu, Eva Johanna Schaefer, Amer M. Zeidan, Aaron D. Goldberg, Eytan M. Stein, Guido Marcucci, Evan C. Chen, Jorge Ramos, R. Coleman Lindsley, Anthony Selwyn Stein, Daniel J. DeAngelo, Donna S. Neuberg, Richard M Stone, Brian J. Ball, Maximilian Stahl
Journal: Blood
Blood (2023) 142 (Supplement 1): 1478.
https://doi.org/10.1182/blood-2023-172763
Published: 2023
Journal Articles

With up to 8 Years of Therapy, Asciminib (ASC) Monotherapy Demonstrated Continued Favorable Efficacy, Safety, and Tolerability in Patients (Pts) with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase (Ph+ CML-CP) without the T315I Mutation: Final Results from the Phase 1 X2101 Study

Andreas Hochhaus, Dong-Wook Kim, Jorge Cortes, Koji Sasaki, Michael Mauro, Timothy P Hughes, Massimo Breccia, Moshe Talpaz, Hironobu Minami, Yeow Tee Goh, Daniel J. DeAngelo, Fabian Lang, Michael C. Heinrich, Valle Gomez G De Soria, Philipp le Coutre, Gessami Sanchez-Olle, Jomy Jose, Nathalie Pognan, Shruti Kapoor, Delphine Rea
Journal: Blood
Blood (2023) 142 (Supplement 1): 450.
https://doi.org/10.1182/blood-2023-187322
Published: 2023
Journal Articles

Initial Results from Summit: An Ongoing, 3-Part, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Phase 2 Clinical Study of Bezuclastinib in Adult Patients with Nonadvanced Systemic Mastocytosis (NonAdvSM)

Prithviraj Bose, Stephen T. Oh, Brian Modena, Anthony M. Hunter, Cem Akin, Mariana Castells, Michael Manning, Richard Herrscher, Frank Siebenhaar, Daniel J. DeAngelo, Tracy I. George, Benjamin Exter, Jenna Zhang, Amanda Pilla, Hina Jolin, Rachael Easton, Lindsay A.M Rein
Journal: Blood
Blood (2023) 142 (Supplement 1): 77.
https://doi.org/10.1182/blood-2023-178927
Published: 2023
Journal Articles

Tagraxofusp in Combination with Azacitidine and Venetoclax in Newly Diagnosed CD123+ Acute Myeloid Leukemia, Expansion Cohort of a Phase 1b Multicenter Trial

Andrew A. Lane, Jacqueline S. Garcia, Evangeline G. Raulston, Jada L. Garzon, Ilene Galinsky, Emilie W. Baxter, Rebecca Leonard, Daniel J. DeAngelo, Marlise R. Luskin, Christopher R. Reilly, Maximilian Stahl, Richard M Stone, Rahul Vedula, Martha Wadleigh, Eric S. Winer, Tariq Mughal, Christopher Brooks, Ira V. Gupta, Kristen E. Stevenson, Donna S. Neuberg, Siyang Ren, Marina Y. Konopleva, Anthony Stein, Naveen Pemmaraju
Journal: Blood
Blood (2023) 142 (Supplement 1): 4277.
https://doi.org/10.1182/blood-2023-180010
Published: 2023
Journal Articles

Assessment of Outcomes of Consolidation Therapy By Number of Cycles of Blinatumomab Received in Newly Diagnosed Measurable Residual Disease Negative Patients with B-Lineage Acute Lymphoblastic Leukemia: In the ECOG-ACRIN E1910 Randomized Phase III National Clinical Trials Network Trial

Selina M Luger, Zhuoxin Sun, Ryan J Mattison, Elisabeth Paietta, Kathryn G. Roberts, Yanming Zhang, Janis Racevckis, Hillard M. Lazarus, Jacob M. Rowe, Daniel A. Arber, Matthew J. Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent L. Wood, Yaqi Zhao, Gang Wu, Ti-Cheng Chang, Wenchao Zhang, Keith W Pratz, Shira N. Dinner, Noelle V. Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L Uy, Deepa Jeyakumar, Tara L Lin, Cheryl L. Willman, Daniel J. DeAngelo, Elad Sharon, Richard F. Little, Harry P. Erba, Richard M Stone, Charles G. Mullighan, Mark R. Litzow, Martin S. Tallman
Journal: Blood
Blood (2023) 142 (Supplement 1): 2877.
https://doi.org/10.1182/blood-2023-189648
Published: 2023
Journal Articles

Venous Thromboembolism in Adolescents and Young Adults with Acute Lymphoblastic Leukemia Treated on a Pediatric-Inspired Regimen

Hari S. Raman, Shai Shimony, Yannis K. Valtis, Yael Flamand, Andrew E. Place, Lewis B. Silverman, Stephen E. Sallan, Lynda M. Vrooman, Andrew M. Brunner, Donna S. Neuberg, Ilene Galinsky, Jacqueline S. Garcia, Eric S. Winer, Martha Wadleigh, Richard M Stone, Jean M. Connors, Daniel J. DeAngelo, Marlise R. Luskin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1456.
https://doi.org/10.1182/blood-2023-178353
Published: 2023
Journal Articles

Cardiovascular Risk Factors Are Common in Myeloproliferative Neoplasms and Portend Worse Survival and Thrombotic Outcomes

Joan How, Orly Leiva, Anna E. Marneth, Baransel Kamaz, Chulwoo J. Kim, Lachelle D. Weeks, Mohammed Wazir, Maximilian Stahl, Daniel J. DeAngelo, R. Coleman Lindsley, Marlise R. Luskin, Gabriela S. Hobbs
Journal: Blood
Blood (2023) 142 (Supplement 1): 4568.
https://doi.org/10.1182/blood-2023-179324
Published: 2023
Journal Articles

Mini-Hyper-CVD Plus Venetoclax for Treatment of Older Adults with Newly Diagnosed Ph-Negative B-ALL or T-ALL

Marlise R. Luskin, Shai Shimony, Julia Keating, Wendy Stock, Hanno Hock, Jacqueline S. Garcia, Maximilian Stahl, Ilene Galinksy, Rebecca Leonard, Howard Weiner, Yael Flamand, Donna S. Neuberg, Richard M Stone, Anthony G. Letai, Eric S. Winer, Marina Y. Konopleva, Nitin Jain, Daniel J. DeAngelo
Journal: Blood
Blood (2023) 142 (Supplement 1): 2875.
https://doi.org/10.1182/blood-2023-174269
Published: 2023
Journal Articles

Preliminary Safety and Efficacy of Emavusertib (CA-4948) in Acute Myeloid Leukemia Patients with FLT3 Mutation

Eric S. Winer, Amit Verma, Stefanie Groepper, Katharina S. S. Götze, Yasmin Abaza, Christoph Schliemann, Gaurav S Choudhary, Wanying Zhao, Cole Gallagher, Reinhard von Roemeling, Daniel J. DeAngelo
Journal: Blood
Blood (2023) 142 (Supplement 1): 2924.
https://doi.org/10.1182/blood-2023-190007
Published: 2023
Journal Articles

Updated Results on a Multicenter Phase II Study of a Dose Intensified Pediatric Regimen in Adults with Acute Lymphoblastic Leukemia: The 06-254 DFCI ALL Consortium Trial

Yannis K. Valtis, Yael Flamand, Shai Shimony, Andrew E. Place, Lewis B. Silverman, Lynda M. Vrooman, Andrew M. Brunner, Stephen E. Sallan, Martha Wadleigh, Jacqueline S. Garcia, Eric S. Winer, Ilene Galinsky, Julie Bergeron, Julie Asch, Matthew D. Seftel, Richard M Stone, Marlise R. Luskin, Daniel J. DeAngelo
Journal: Blood
Blood (2023) 142 (Supplement 1): 4238.
https://doi.org/10.1182/blood-2023-181014
Published: 2023
Journal Articles

A Phase 1 Study of Avapritinib in Combination with Decitabine in Patients with Systemic Mastocytosis with an Associated Hematologic Neoplasm

Andrew T. Kuykendall, Somedeb Ball, Jason Gotlib, Cecilia Y. Arana Yi, Tsewang Tashi, Raajit K. Rampal, Daniel J. DeAngelo, Virginia O. Volpe, Kristen Marie Pettit, Rami S. Komrokji, Eric Padron
Journal: Blood
Blood (2023) 142 (Supplement 1): 6441.
https://doi.org/10.1182/blood-2023-184652
Published: 2023
Journal Articles

Obecabtagene Autoleucel (obe-cel, AUTO1) for Relapsed/Refractory Adult B-cell Acute Lymphoblastic Leukemia (R/R B-ALL): Pooled Analysis of the Ongoing FELIX Phase Ib/II Study

Claire Roddie, Karamjeet S. Sandhu, Eleni Tholouli, Paul Shaughnessy, Pere Barba, Manuel Guerreiro, Michael R. Bishop, Jean A. Yared, Armin Ghobadi, Deborah Yallop, Aaron C. Logan, Amer M. Beitinjaneh, Jeremy M. Pantin, Martha Arellano, Sridhar Chaganti, Ram Malladi, Tobias Menne, Virginia Escamilla Gómez, Katharine Hodby, Krishna Gundabolu, Luke Mountjoy, Kristen M. O'Dwyer, Sameem Abedin, Hassan Alkhateeb, Bijal D. Shah, Pierre Lao-Sirieix, Gianfranco Pittari, Kapil Saxena, Yiyun Zhang, Wolfram Brugger, Martin A. Pule, Jae H. Park, Daniel J. DeAngelo, Elias Jabbour
Journal: Blood
Blood (2023) 142 (Supplement 1): 222.
https://doi.org/10.1182/blood-2023-179454
Published: 2023
Journal Articles

Intensive Induction Chemotherapy (IC) Vs Hypomethylating Agents + Venetoclax (HMA/VEN) in IDH1- or IDH2 -Mutant Newly Diagnosed Acute Myeloid Leukemia (AML) - a Multicenter Cohort Study

Jan Philipp Bewersdorf, Shai Shimony, Rory M. Shallis, Yiwen Liu, Eva Johanna Schaefer, Amer M. Zeidan, Aaron D. Goldberg, Eytan M. Stein, Guido Marcucci, R. Coleman Lindsley, Evan C. Chen, Jorge Ramos, Anthony Selwyn Stein, Daniel J. DeAngelo, Donna S. Neuberg, Richard M Stone, Brian J. Ball, Maximilian Stahl
Journal: Blood
Blood (2023) 142 (Supplement 1): 1589.
https://doi.org/10.1182/blood-2023-174283
Published: 2023
Journal Articles

Molecular Ontogeny in AML Is Both Prognostic and Predictive in Patients Treated with Hypomethylating Agents Plus Venetoclax

Shai Shimony, Jacqueline S. Garcia, Julia Keating, Evan C. Chen, Marlise R. Luskin, Maximilian Stahl, Donna S. Neuberg, Daniel J. DeAngelo, Richard M Stone, R. Coleman Lindsley
Journal: Blood
Blood (2023) 142 (Supplement 1): 977.
https://doi.org/10.1182/blood-2023-173935
Published: 2023
Journal Articles

A Phase I Study of Asciminib (ABL001) in Combination with Dasatinib and Prednisone for BCR-ABL1-Positive ALL and Blast Phase CML in Adults

Marlise R. Luskin, Mark Alan Murakami, Julia Keating, Eric S. Winer, Jacqueline S. Garcia, Maximilian Stahl, Martha Wadleigh, Yael Flamand, Donna S. Neuberg, Ilene Galinsky, Rebecca Leonard, Ella Hagopian, Chase M Weizer, Carlin McLanahan, Richard M Stone, Eunice S. Wang, Wendy Stock, Daniel J. DeAngelo
Journal: Blood
Blood (2023) 142 (Supplement 1): 965.
https://doi.org/10.1182/blood-2023-174246
Published: 2023
Journal Articles

No Increased Incidence of Bleeding in Essential Thrombocythemia Patients with Extreme Thrombocytosis

Rathnam K. Venkat, Robert A. Redd, Martin J. Aryee, Anna E. Marneth, Baransel Kamaz, Chulwoo J. Kim, Mohammed Wazir, Lachelle D. Weeks, Maximilian Stahl, Daniel J. DeAngelo, Coleman Lindsley, Marlise R. Luskin, Gabriela S. Hobbs, Joan How
Journal: Blood
Blood (2023) 142 (Supplement 1): 1839.
https://doi.org/10.1182/blood-2023-187530
Published: 2023
Journal Articles

Post Allogeneic Stem Cell Transplant Outcomes Following Response to Hypomethylating Agent Therapy in Myelodysplastic Syndromes Are Predicted By Persistent International Prognostic Scoring System-Molecular Risk

Stacey M Frumm, Haesook T. Kim, Amar H Kelkar, Vincent T. Ho, Mahasweta Gooptu, Christopher James Gibson, John Koreth, Roman M. Shapiro, Rizwan Romee, Sarah Nikiforow, Joseph H. Antin, Robert J. Soiffer, Benjamin Rolles, Shai Shimony, Jan Philipp Bewersdorf, Tariq Kewan, Abdulrahman Alhajahjeh, Marlise R. Luskin, Jacqueline S. Garcia, Evan C. Chen, Andrew A. Lane, Martha Wadleigh, Eric S. Winer, Richard M Stone, Daniel J. DeAngelo, Amer M. Zeidan, Coleman Lindsley, Corey Cutler, Maximilian Stahl
Journal: Blood
Blood (2023) 142 (Supplement 1): 3618.
https://doi.org/10.1182/blood-2023-185220
Published: 2023