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David H. McKenna
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Journal Articles

Impact of Autologous Hematopoietic Cell Transplant (HCT) Followed By Dendritic Cell/Myeloma Fusion Vaccine with Lenalidomide Maintenance in Increasing Multiple Myeloma (MM) Immunity (BMT CTN 1401)

David J. Chung, Nina Shah, Dina Stroopinsky, Juan WU, Lina Bisharat, Natalie S. Callander, Brent R. Logan, Kenneth C. Anderson, Thinle Chodon, Meera Mohan, Steven Devine, Yvonne A. Efebera, Nancy Geller, Peiman Hematti, Leona A. Holmberg, Alan Howard, Bryon Johnson, Hillard M Lazarus, Ehsan Malek, Philip L. McCarthy, David H. McKenna, Adam M. Mendizabal, Nikhil C. Munshi, Lynn O'Donnell, Aaron P. Rapoport, Ajay K. Nooka, Jane Reese, Robert J. Soiffer, Lynne Uhl, Giulia Cheloni, Dimitra Karagkouni, Ioannis Vlachos, James W. Young, Jacalyn Rosenblatt, Edmund K. Waller, Marcelo C Pasquini, David Avigan
Journal: Blood
Blood (2021) 138 (Supplement 1): 899.
https://doi.org/10.1182/blood-2021-149659
Published: 2021
Journal Articles

Gda-201, a Novel Metabolically Enhanced Allogeneic Natural Killer (NK) Cell Product Yields High Remission Rates in Patients with Relapsed/Refractory Non-Hodgkin Lymphoma (NHL): 2-Year Survival and Correlation with Cytokine IL7

Veronika Bachanova, Joseph E. Maakaron, Frank Cichocki, David H. McKenna, Qing Cao, Todd E. DeFor, Murali Janakiram, Rose Wangen, Zuzan Cayci, Bartosz Grzywacz, Ronit Simantov, Tracey Lodie, Jeffrey S. Miller
Journal: Blood
Blood (2021) 138 (Supplement 1): 3854.
https://doi.org/10.1182/blood-2021-149989
Published: 2021
Journal Articles

Results of a Phase 1 Trial of Gda-201, Nicotinamide-Expanded Allogeneic Natural Killer (NK) Cells in Patients with Refractory Non-Hodgkin Lymphoma (NHL) and Multiple Myeloma

Veronika Bachanova, MD PhD, Joseph Maakaron, MD, David H. McKenna, MD, Qing Cao, MS, Todd E. DeFor, MS, Fiona He, MD, Murali Janakiram, MD, Rose Wangen, Zuzan Cayci, MD, Bartosz Grzywacz, MD, Ronit Simantov, MD, Tracey Lodie, PhD, Jeffrey S. Miller, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6.
https://doi.org/10.1182/blood-2020-142419
Published: 2020
Journal Articles

Mgta-456, an Aryl Hydrocarbon Receptor (AHR) Antagonist Based Expansion of CD34+ Hematopoietic Stem Cells (HSC), Permits Selection of Better HLA Matched Cord Blood Units (CBUs) and Promotes Faster Neutrophil Recovery and Uniform Engraftment with Potentially Less Acute Graft-Vs-Host Disease (GVHD)

Heather Stefanski, MD PhD, Claudio G Brunstein, MD PhD, David H. McKenna, MD, Darin Sumstad, MLS, Jeffrey S. Miller, MD, Bruce R. Blazar, MD, Todd E. DeFor, MS, Anthony E. Boitano, PhD, Michael P. Cooke, PhD, Glen D. Raffel, MD PhD, John C. Davis, Jr., MD MPH, MS, John E. Wagner, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 804.
https://doi.org/10.1182/blood-2019-122329
Published: 2019
Journal Articles

Results of a Phase 1 Trial of Gda-201, Nicotinamide-Expanded Allogeneic Natural Killer Cells (NAM-NK) in Patients with Refractory Non-Hodgkin Lymphoma (NHL) and Multiple Myeloma (MM)

Veronika Bachanova, MD PhD, David H. McKenna, MD, Xianghua Luo, PhD, Todd E. DeFor, MS, Fiona He, MD, Murali Janakiram, MD MS, Erica D. Warlick, MD, Rose Wangen, Zuzan Cayci, MD, Bartosz Grzywacz, MD, Guy Brachya, PhD, Tony Peled, MSc, Jeffrey S. Miller, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 777.
https://doi.org/10.1182/blood-2019-130476
Published: 2019
Journal Articles

First-in-Human Clinical Trial to Determine the Safety and Potency of Inducible T Regulatory Cells after Allogeneic Hematopoietic Cell Transplantation

Margaret L. MacMillan, MD, Keli Lee Hippen, PhD, David H. McKenna, MD, Todd E. DeFor, MS, Erica D. Warlick, MD, Claudio G Brunstein, MD PhD, Jeffrey S. Miller, MD, Daniel J. Weisdorf, MD, Bruce R. Blazar, MD, John E. Wagner, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2112.
https://doi.org/10.1182/blood-2018-99-113100
Published: 2018
Journal Articles

NK Cell Homing and Persistence in Bone Marrow after Adoptive Immunotherapy Correlates with Therapy Response

Bartosz Grzywacz, MD, Elizabeth L. Courville, MD, David H. McKenna, MD, Jeffrey S. Miller, MD, Sarah Cooley, MD, Laura Moench, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4459.
https://doi.org/10.1182/blood.V130.Suppl_1.4459.4459
Published: 2017
Journal Articles

Clinical Translation of Pluripotent Cell-Derived Off-the-Shelf Natural Killer Cell Cancer Immunotherapy

Frank Cichocki, Ryan Bjordahl, PhD, Svetlana Gaidarova, Paul Rogers, Raedun Clarke, PhD, Brian Groff, Stacey Moreno, Ramzey Abujarour, PhD, Megan Robinson, Greg Bonello, PhD, Tom Lee, PhD, Weijie Lan, PhD, Betsy Rezner, BS, Stewart Abbot, Darin Sumstad, MLS, Bruce Blazar, MD, Daniel Shoemaker, PhD, Scott Wolchko, Dan Kaufman, MD, David H. McKenna, MD, Bahram Valamehr, PhD, Sarah Cooley, MD, Jeffrey S. Miller, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 656.
https://doi.org/10.1182/blood.V130.Suppl_1.656.656
Published: 2017
Journal Articles

Neurological Consequences of Cytokine Release Syndrome Following Subcutaneous Recombinant IL-15 and Haploidentical Donor Natural Killer Cell Therapy for Advanced Acute Myeloid Leukemia

Sarah Cooley, MD, Fiona He, MD BS, BA, Veronika Bachanova, MD PhD, Greg M Vercellotti, MD FACP, Todd E. DeFor, MS, Julie Curtsinger, Paul Alexander Robertson, MD, Kevin C Conlon, MD, Thomas A Waldmann, MD, David H. McKenna, MD, Bruce Blazar, MD, Daniel J. Weisdorf, MD, Jeffrey S. Miller, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2649.
https://doi.org/10.1182/blood.V130.Suppl_1.2649.2649
Published: 2017
Journal Articles

Development and Scale-up of a Novel GMP Method for Enrichment and Expansion of Terminally Differentiated Adaptive Natural Killer Cells (FATE-NK100) with Enhanced Anti-Tumor Function

Frank Cichocki, PhD, Bahram Valamehr, PhD MBA, Dhifaf Sarhan, PhD, Bin Zhang, Sarah Cooley, MD, Michael R. Verneris, MD, Bruce R. Blazar, MD, Ryan Bjordahl, PhD, Betsy Rezner, BS, Paul Rogers, PhD, Chad Green, David H McKenna, MD, Daniel Shoemaker, PhD, Scott Wolchko, MS, Jeffrey S. Miller, MD
Journal: Blood
Blood (2016) 128 (22): 1225.
https://doi.org/10.1182/blood.V128.22.1225.1225
Published: 2016
Journal Articles

Umbilical cord blood–derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

Claudio G. Brunstein, Jeffrey S. Miller, David H. McKenna, Keli L. Hippen, Todd E. DeFor, Darin Sumstad, Julie Curtsinger, Michael R. Verneris, Margaret L. MacMillan, Bruce L. Levine, James L. Riley, Carl H. June, Chap Le, Daniel J. Weisdorf, Philip B. McGlave, Bruce R. Blazar, John E. Wagner
Journal: Blood
Blood (2016) 127 (8): 1044–1051.
https://doi.org/10.1182/blood-2015-06-653667
Published: 2016
Includes: Supplemental data
Journal Articles

Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein

Clinical Trials & Observations
Veronika Bachanova, Sarah Cooley, Todd E. Defor, Michael R. Verneris, Bin Zhang, David H. McKenna, Julie Curtsinger, Angela Panoskaltsis-Mortari, Dixie Lewis, Keli Hippen, Philip McGlave, Daniel J. Weisdorf, Bruce R. Blazar, Jeffrey S. Miller
Journal: Blood
Blood (2014) 123 (25): 3855–3863.
https://doi.org/10.1182/blood-2013-10-532531
Published: 2014
Includes: Supplemental data
Journal Articles

Impact of Umbilical Cord Blood (UCB) T Regulatory Cells (Tregs) On Infection Risk Early After UCB Transplant

Claudio G Brunstein, MD, Bruce R. Blazar, MD, Jeffrey S. Miller, MD, Qing Cao, MS, Keli Hippen, PhD, David H McKenna, MD, John E. Wagner, MD
Journal: Blood
Blood (2012) 120 (21): 4188.
https://doi.org/10.1182/blood.V120.21.4188.4188
Published: 2012
Journal Articles

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

Clinical Trials & Observations
Claudio G. Brunstein, Jeffrey S. Miller, Qing Cao, David H. McKenna, Keli L. Hippen, Julie Curtsinger, Todd DeFor, Bruce L. Levine, Carl H. June, Pablo Rubinstein, Philip B. McGlave, Bruce R. Blazar, John E. Wagner
Journal: Blood
Blood (2011) 117 (3): 1061–1070.
https://doi.org/10.1182/blood-2010-07-293795
Published: 2011
Includes: Supplemental data
Journal Articles

Adoptive Transfer of Umbilical Cord Blood (UCB)-Derived Regulatory T Cells (Tregs) to Recipients of Nonmyeloablative Unrelated Double UCB Transplantation.

Claudio Brunstein, Keli L. Hippen, David H. McKenna, Qing Cao, Julie Curtsinger, Darin Sumstad, Bruce L. Levine, PhD, James L. Riley, Carl H. June, MD, Jeffrey S. Miller, Bruce R. Blazar, John E. Wagner
Journal: Blood
Blood (2009) 114 (22): 513.
https://doi.org/10.1182/blood.V114.22.513.513
Published: 2009
Journal Articles

Allogeneic Donor NK Cell Infusion and IL-2 for Patients with Refractory B-Cell Non-Hodgkin Lymphoma.

Veronika Bachanova, Linda J. Burns, MD, David H. McKenna, Julie Curtsinger, Sarah Cooley, Daniel J. Weisdorf, MD, Jeffrey S. Miller
Journal: Blood
Blood (2009) 114 (22): 3036.
https://doi.org/10.1182/blood.V114.22.3036.3036
Published: 2009
Journal Articles

Relapse risk after umbilical cord blood transplantation: enhanced graft-versus-leukemia effect in recipients of 2 units

Michael R. Verneris, Claudio G. Brunstein, Juliet Barker, Margaret L. MacMillan, Todd DeFor, David H. McKenna, Michael J. Burke, Bruce R. Blazar, Jeffrey S. Miller, Philip B. McGlave, Daniel J. Weisdorf, John E. Wagner
Journal: Blood
Blood (2009) 114 (19): 4293–4299.
https://doi.org/10.1182/blood-2009-05-220525
Published: 2009
Journal Articles

Isolation and Characterization of Umbilical Cord Blood-Derived Multipotent Stem Cells Arising from Adherent CD45+/CD34+ Cell Subset.

David H. McKenna, MD, Sheryl Adams, MT (ASCP), Eileen Emrick, MT (ASCP), Stacey Sprague, MT (ASCP), Barbara M. Tigges, PhD, Daniel P. Collins, PhD
Journal: Blood
Blood (2005) 106 (11): 1064.
https://doi.org/10.1182/blood.V106.11.1064.1064
Published: 2005