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Journal Articles

Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPL

Kathryn S. Potts, Tobias J. Sargeant, Caleb A. Dawson, Emma C. Josefsson, Douglas J. Hilton, Warren S. Alexander, Samir Taoudi

Blood (2015) 126 (6): 807–816.

https://doi.org/10.1182/blood-2014-12-616607

Published: 2015

Includes: Supplemental data

Journal Articles

A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo

Kathryn S. Potts, Tobias J. Sargeant, John F. Markham, Wei Shi, Christine Biben, Emma C. Josefsson, Lachlan W. Whitehead, Kelly L. Rogers, Anna Liakhovitskaia, Gordon K. Smyth, Benjamin T. Kile, Alexander Medvinsky, Warren S. Alexander, Douglas J. Hilton, Samir Taoudi

Blood (2014) 124 (17): 2725–2729.

https://doi.org/10.1182/blood-2014-02-559468

Published: 2014

Includes: Supplemental data

Journal Articles

Polycomb repressive complex 2 (PRC2) suppresses Eμ- myc lymphoma

Stanley C. W. Lee, Belinda Phipson, Craig D. Hyland, Huei San Leong, Rhys S. Allan, Aaron Lun, Douglas J. Hilton, Stephen L. Nutt, Marnie E. Blewitt, Gordon K. Smyth, Warren S. Alexander, Ian J. Majewski

Blood (2013) 122 (15): 2654–2663.

https://doi.org/10.1182/blood-2013-02-484055

Published: 2013

Includes: Supplemental data

Journal Articles

A Novel DNM2 Mutation Displaying Embryonic Lethality and Impaired Transferrin Uptake Identified in a Mouse ENU Mutagenesis Screen for Genes Perturbing Erythropoiesis

Fiona C Brown, BSc, Michael Collett, BSc, Phillip J Robinson, PhD, James C Whisstock, PhD, Douglas J. Hilton, Benjamin T. Kile, Stephen M Jane, FRACP, FRCPA, MBBS, PhD, David J. Curtis, M.D., Ph.D.

Blood (2012) 120 (21): 608.

https://doi.org/10.1182/blood.V120.21.608.608

Published: 2012

Journal Articles

Activation of the NLRP1 Inflammasome Induces the Pyroptotic Death of Hematopoietic Progenitor Cells

Seth L. Masters, Mordechay Gerlic, Donald Metcalf, Simon P. Preston, Marc Pellegrini, Joanne A. O'Donnell, Kate McArthur, Tracey M. Baldwin, Stephane Chevrier, Cameron J. Nowell, Louise H. Cengia, Katya J. Henley, Janelle E. Collinge, Daniel L. Kastner, Lionel Feigenbaum, Douglas J. Hilton, Warren S. Alexander, Ben A. Croker, Benjamin T. Kile

Blood (2012) 120 (21): 1213.

https://doi.org/10.1182/blood.V120.21.1213.1213

Published: 2012

Journal Articles

ENU Mutagenesis in the Mouse for Identification of Genes Regulating Erythropoiesis: a Mouse Mutant with An Activating Mutation of the KCl Cotransporter, KCC1 Causing Dehydrated Red Cells

David J. Curtis, MD, PhD, Fiona Brown, BSc, James Wiley, MD PhD, Shwen Ho, PhD, Douglas J. Hilton, PhD, Benjamin T. Kile, PhD, Stephen M Jane

Blood (2011) 118 (21): 684.

https://doi.org/10.1182/blood.V118.21.684.684

Published: 2011

Journal Articles

Erg is required for self-renewal of hematopoietic stem cells during stress hematopoiesis in mice

Ashley P. Ng, Stephen J. Loughran, Donald Metcalf, Craig D. Hyland, Carolyn A. de Graaf, Yifang Hu, Gordon K. Smyth, Douglas J. Hilton, Benjamin T. Kile, Warren S. Alexander

Blood (2011) 118 (9): 2454–2461.

https://doi.org/10.1182/blood-2011-03-344739

Published: 2011

Includes: Supplemental data

Journal Articles

An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation

Nhu-Y. N. Nguyen, Mhairi J. Maxwell, Lisa M. Ooms, Elizabeth M. Davies, Adrienne A. Hilton, Janelle E. Collinge, Douglas J. Hilton, Benjamin T. Kile, Christina A. Mitchell, Margaret L. Hibbs, Stephen M. Jane, David J. Curtis

Blood (2011) 117 (20): 5362–5371.

https://doi.org/10.1182/blood-2011-01-331041

Published: 2011

Includes: Supplemental data

Journal Articles

Pathways Regulating Blood Cell Production

Douglas J. Hilton, PhD

Blood (2010) 116 (21): SCI-41.

https://doi.org/10.1182/blood.V116.21.SCI-41.SCI-41

Published: 2010

Journal Articles

Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells

Ian J. Majewski, Matthew E. Ritchie, Belinda Phipson, Jason Corbin, Miha Pakusch, Anja Ebert, Meinrad Busslinger, Haruhiko Koseki, Yifang Hu, Gordon K. Smyth, Warren S. Alexander, Douglas J. Hilton, Marnie E. Blewitt

Blood (2010) 116 (5): 731–739.

https://doi.org/10.1182/blood-2009-12-260760

Published: 2010

Includes: Supplemental data

Journal Articles

Critical roles for c-Myb in lymphoid priming and early B-cell development

Kylie T. Greig, Carolyn A. de Graaf, James M. Murphy, Marina R. Carpinelli, Swee Heng Milon Pang, Jon Frampton, Benjamin T. Kile, Douglas J. Hilton, Stephen L. Nutt

Blood (2010) 115 (14): 2796–2805.

https://doi.org/10.1182/blood-2009-08-239210

Published: 2010

Includes: Supplemental data

Journal Articles

Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization

Matthew J. Christopher, Fulu Liu, Matthew J. Hilton, Fanxin Long, Daniel C. Link

Blood (2009) 114 (7): 1331–1339.

https://doi.org/10.1182/blood-2008-10-184754

Published: 2009

Includes: Supplemental data

Journal Articles

Mutational inhibition of c- Myb or p300 ameliorates treatment-induced thrombocytopenia

Douglas J. Hilton, Benjamin T. Kile, Warren S. Alexander

Blood (2009) 113 (22): 5599–5604.

https://doi.org/10.1182/blood-2008-12-195255

Published: 2009

Journal Articles

Novel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant

Gerhard Rank, Rosemary Sutton, Vikki Marshall, Rachel J. Lundie, Jacinta Caddy, Tony Romeo, Kate Fernandez, Matthew P. McCormack, Brian M. Cooke, Simon J. Foote, Brendan S. Crabb, David J. Curtis, Douglas J. Hilton, Benjamin T. Kile, Stephen M. Jane

Blood (2009) 113 (14): 3352–3362.

https://doi.org/10.1182/blood-2008-08-172841

Published: 2009

Includes: Supplemental data

Journal Articles

Hematopoietic defects in the Ts1Cje mouse model of Down syndrome

Catherine L. Carmichael, Ian J. Majewski, Warren S. Alexander, Donald Metcalf, Douglas J. Hilton, Chelsee A. Hewitt, Hamish S. Scott

Blood (2009) 113 (9): 1929–1937.

https://doi.org/10.1182/blood-2008-06-161422

Published: 2009

Includes: Supplemental data

Journal Articles

Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl −/− mice

Maria Kauppi, James M. Murphy, Carolyn A. de Graaf, Craig D. Hyland, Kylie T. Greig, Donald Metcalf, Adrienne A. Hilton, Nicos A. Nicola, Benjamin T. Kile, Douglas J. Hilton, Warren S. Alexander

Blood (2008) 112 (8): 3148–3153.

https://doi.org/10.1182/blood-2007-10-119677

Published: 2008

Journal Articles

Suppression of CXCL12 Production by Bone Marrow Osteoblasts Is a Common and Critical Pathway for Cytokine-Induced Mobilization.

Matthew J. Christopher, Matthew J. Hilton, PhD, Fanxin Long, PhD, Daniel C. Link, MD

Blood (2007) 110 (11): 220.

https://doi.org/10.1182/blood.V110.11.220.220

Published: 2007

Journal Articles

Suppressor of cytokine signaling 3 regulates CD8 T-cell proliferation by inhibition of interleukins 6 and 27

Christine Brender, Gillian M. Tannahill, Brendan J. Jenkins, Joel Fletcher, Ruth Columbus, Christiaan J. M. Saris, Matthias Ernst, Nicos A. Nicola, Douglas J. Hilton, Warren S. Alexander, Robyn Starr

Blood (2007) 110 (7): 2528–2536.

https://doi.org/10.1182/blood-2006-08-041541

Published: 2007

Journal Articles

The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo

Kristy Boyle, Paul Egan, Steven Rakar, Tracy A. Willson, Ian P. Wicks, Donald Metcalf, Douglas J. Hilton, Nicos A. Nicola, Warren S. Alexander, Andrew W. Roberts, Lorraine Robb

Blood (2007) 110 (5): 1466–1474.

https://doi.org/10.1182/blood-2007-03-079178

Published: 2007

Includes: Supplemental data

Journal Articles

Suppressor of Cytokine Signaling-3 (SOCS3) Selectively Modulates Progenitor Cell Proliferation and Differentiation Induced by G-CSF and IL-6, and the Synergy between SCF and IL-6.

Andrew W. Roberts, MBBS, PhD, Lisa Mielke, BSc, Sam Wormald, PhD, Hiu Kiu, BSc, Ben A. Croker, PhD, Douglas J. Hilton, PhD, Donald Metcalf, MD, Warren S. Alexander, PhD

Blood (2006) 108 (11): 631.

https://doi.org/10.1182/blood.V108.11.631.631

Published: 2006

NARROW

Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPL

A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo

Polycomb repressive complex 2 (PRC2) suppresses Eμ- myc lymphoma

A Novel DNM2 Mutation Displaying Embryonic Lethality and Impaired Transferrin Uptake Identified in a Mouse ENU Mutagenesis Screen for Genes Perturbing Erythropoiesis

Activation of the NLRP1 Inflammasome Induces the Pyroptotic Death of Hematopoietic Progenitor Cells

ENU Mutagenesis in the Mouse for Identification of Genes Regulating Erythropoiesis: a Mouse Mutant with An Activating Mutation of the KCl Cotransporter, KCC1 Causing Dehydrated Red Cells

Erg is required for self-renewal of hematopoietic stem cells during stress hematopoiesis in mice

An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation

Pathways Regulating Blood Cell Production

Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells

Critical roles for c-Myb in lymphoid priming and early B-cell development

Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization

Mutational inhibition of c- Myb or p300 ameliorates treatment-induced thrombocytopenia

Novel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant

Hematopoietic defects in the Ts1Cje mouse model of Down syndrome

Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl −/− mice

Suppression of CXCL12 Production by Bone Marrow Osteoblasts Is a Common and Critical Pathway for Cytokine-Induced Mobilization.

Suppressor of cytokine signaling 3 regulates CD8 T-cell proliferation by inhibition of interleukins 6 and 27

The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo

Suppressor of Cytokine Signaling-3 (SOCS3) Selectively Modulates Progenitor Cell Proliferation and Differentiation Induced by G-CSF and IL-6, and the Synergy between SCF and IL-6.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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