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Journal Articles

ATM germ line pathogenic variants affect outcomes in children with ataxia-telangiectasia and hematological malignancies

Clinical Trials & Observations
Sarah Elitzur, Ruth Shiloh, Jan L. C. Loeffen, Agata Pastorczak, Masatoshi Takagi, Simon Bomken, Andre Baruchel, Thomas Lehrnbecher, Sarah K. Tasian, Oussama Abla, Nira Arad-Cohen, Itziar Astigarraga, Miriam Ben-Harosh, Nicole Bodmer, Triantafyllia Brozou, Francesco Ceppi, Liliia Chugaeva, Luciano Dalla Pozza, Stephane Ducassou, Gabriele Escherich, Roula Farah, Amber Gibson, Henrik Hasle, Julieta Hoveyan, Elad Jacoby, Janez Jazbec, Stefanie Junk, Alexandra Kolenova, Jelena Lazic, Luca Lo Nigro, Nizar Mahlaoui, Lane Miller, Vassilios Papadakis, Lucie Pecheux, Marta Pillon, Ifat Sarouk, Jan Stary, Eftichia Stiakaki, Marion Strullu, Thai Hoa Tran, Marek Ussowicz, Jaime Verdu-Amoros, Anna Wakulinska, Joanna Zawitkowska, Dominique Stoppa-Lyonnet, A. Malcolm Taylor, Yosef Shiloh, Shai Izraeli, Veronique Minard-Colin, Kjeld Schmiegelow, Ronit Nirel, Andishe Attarbaschi, Arndt Borkhardt
Journal: Blood
Blood (2024) 144 (11): 1193–1205.
https://doi.org/10.1182/blood.2024024283
Published: 2024
Includes: Supplemental data
Journal Articles

Role of the DNA Repair Machinery in Childhood B-Lineage Acute Lymphoblastic Leukemia: Aberrations of NBS 1, Fancd 2, Palb 2 Genes and Expression of BRCA 1 and BRCA 2

Luca Lo Nigro, Daria La Cognata, Nellina Andriano, Emanuela Cannata, Manuela La Rosa, Marta Arrabito, Giovanna Russo
Journal: Blood
Blood (2023) 142 (Supplement 1): 2982.
https://doi.org/10.1182/blood-2023-187333
Published: 2023
Journal Articles

Characterization of the Molecular Landscape of Pediatric Acute Myeloid Leukemia: A Retrospective AIEOP AML2013/01 Study

Maddalena Benetton, Pietro Merli, Nicola Santoro, Luca Lo Nigro, Claudia Tregnago, Ambra Da Ros, Katia Polato, Veronica Zampieri, Barbara Michielotto, Samuela Francescato, Anna Leszl, Riccardo Masetti, Barbara Buldini, Alessandra Biffi, Franca Fagioli, Carmelo Rizzari, Franco Locatelli, Martina Pigazzi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1580.
https://doi.org/10.1182/blood-2023-186458
Published: 2023
Journal Articles

Final Results of the AIEOP (Associazione Italiana Ematologia/Oncologia Pediatrica) AML 2013 Prospective Randomized Trial in Childhood Acute Myeloid Leukemia (AML)

Franco Locatelli, Barbara Buldini, Martina Pigazzi, Carmelo Rizzari, Rosanna Cuccurullo, Franca Fagioli, Manuela Tumino, Luca Lo Nigro, Maria Giuseppina Cefalo, Luisa Strocchio, Marco Zecca, Marco Becilli, Andrea Pession, Nicola Santoro, Concetta Micalizzi, Riccardo Masetti, Pietro Merli
Journal: Blood
Blood (2023) 142 (Supplement 1): 728.
https://doi.org/10.1182/blood-2023-188682
Published: 2023
Journal Articles

Somatic and Germline Cohesin Genes Alterations in Pediatric Acute Lymphoblastic Leukemia

Stefano Rebellato, Claudia Saitta, Laura Rachele Bettini, Daniela Silvestri, Orietta Spinelli, Agata Pastorczak, Danielle Brandes, Ute Fischer, Arndt Borkhardt, Sabine Strehl, Luca Lo Nigro, Barbara Buldini, Julia Hauer, Franziska Auer, Lennart Kester, Roland P. Kuiper, Luciana Vinti, Franco Locatelli, Andrea Biondi, Grazia Fazio, Giovanni Cazzaniga
Journal: Blood
Blood (2023) 142 (Supplement 1): 1600.
https://doi.org/10.1182/blood-2023-189244
Published: 2023
Journal Articles

ATM Germline Pathogenic Variants Affect Treatment Outcomes in Children with Acute Lymphoblastic Leukemia/Lymphoma and Ataxia Telangiectasia

Sarah Elitzur, Ruth Shiloh, Jan Loeffen, Agata Pastorczak, Masatoshi Takagi, Simon Bomken, Andre Baruchel, Stephane Ducassou, Nizar Mahlaoui, Marion Strullu, Thomas Lehrnbecher, Kjeld Schmiegelow, Oussama Abla, Liliia Anderzhanova, Nira Arad-Cohen, Itziar Astigarraga, Miriam Ben-Harosh, Francesco Ceppi, Nicole Bodmer, Triantafyllia Brozou, Luciano Dalla-Pozza, Gabriele Escherich, Roula Farah, Amber Gibson, Henrik Hasle, Julieta Hoveyan, Elad Jacoby, Janez Jazbec, Alexandra Kolenova, Jelena Lazic, Luca Lo Nigro, Lane Miller, Vassilios Papadakis, Lucie Pecheux, Marta Pillon, Ifat Sarouk, Jan Stary, Eftichia Stiakaki, Sarah K. Tasian, Thai Hoa Tran, Marek Ussowicz, Jose Jaime Verdu-Amoros, Anna Wakulinska, Joanna Zawitkowska, Dominique Stoppa-Lyonnet, Malcolm Taylor, Yosef Shiloh, Shai Izraeli, Ronit Nirel, Veronique Minard-Colin, Andishe Attarbaschi, Arndt Borkhardt
Journal: Blood
Blood (2023) 142 (Supplement 1): 520.
https://doi.org/10.1182/blood-2023-179333
Published: 2023
Journal Articles

Ph-like and IKZF1plus Features in Children with Down Syndrome and B Cell Precursor Acute Lymphoblastic Leukemia

Chiara Palmi, Silvia Bresolin, Stefanie V. Junk, Grazia Fazio, Daniela Silvestri, Marketa Zaliova, Athanasios Oikonomou, Katerina Scharov, Martin Stanulla, Anja Moericke, Martin Zimmermann, Martin Schrappe, Barbara Buldini, Claudia Saitta, Marta Galbiati, Michela Bardini, Sanil Bhatia, Arndt Borkhardt, Luca Lo Nigro, Valentino Conter, Maria Grazia Valsecchi, Andrea Biondi, Geertruij Te Kronnie, Gunnar Cario, Giovanni Cazzaniga
Journal: Blood
Blood (2022) 140 (Supplement 1): 6367–6368.
https://doi.org/10.1182/blood-2022-169131
Published: 2022
Journal Articles

T-Cell Lymphocyte Kinetics As a Predictive Biomarker of Blinatumomab MRD Response in ALL-B Patients: A Single-Center Prospective Study

Uros Markovic, Andrea Duminuco, Nunziatina Laura Parrinello, Luca Lo Nigro, Elisa Mauro, Calogero Vetro, Marina Parisi, Cinzia Maugeri, Giuseppe Milone, Alessandra Romano, Francesco Di Raimondo, Salvatore Leotta
Journal: Blood
Blood (2022) 140 (Supplement 1): 11847–11848.
https://doi.org/10.1182/blood-2022-170177
Published: 2022
Journal Articles

Clinical Implications of Minimal Residual Disease Detection in Infants with KMT2A -Rearranged Acute Lymphoblastic Leukemia Treated on the Interfant-06 Protocol

Janine Stutterheim, MDPhD, Inge M. van der Sluis, MD PhD, Paola De Lorenzo, Julia Alten, MD, Philip Ancliff, MD, Andishe Attarbaschi, MD, Benoit Brethon, MD, Andrea Biondi, MD, Myriam Campbell, MD, Giovanni Cazzaniga, PhD, Gabriele Escherich, MD, Alina Ferster, MD, Rishi Sury Kotecha, MBBChir, PhD, Birgitte Lausen, MD, Chi Kong Li, MD, Luca Lo Nigro, PhDMD, Franco Locatelli, MD PhD, Rolf Marschalek, PhD, Martin Schrappe, MDPhD, Jan Stary, MD PhD, Ajay Vora, MD, Jan Zuna, PhD, Vincent H.J. Van Der Velden, PhD, Tomasz Szczepanski, MD PhD, Maria Grazia Valsecchi, PhD, Rob Pieters, MDPhDMSc
Journal: Blood
Blood (2020) 136 (Supplement 1): 41–42.
https://doi.org/10.1182/blood-2020-134303
Published: 2020
Journal Articles

Transcriptomic Profile Identified a Specific Signature in Children with Acute Myeloid Leukemia (AML) and Primary Induction Failure (PIF): Preliminary Data and Future Perspectives

Luca Lo Nigro, PhD MD, Vincenza Barresi, Prof, Nellina Andriano, BD, Giulio Pulvirenti, MD, Giorgia Spampinato, BD, Paola Bonaccorso, BD, Valeria Iachelli, BD, Manuela La Rosa, BD, Emanuela Cannata, MD PhD, Andrea Di Cataldo, Prof, Giovanna Russo, MD, Daniele Condorelli, Prof
Journal: Blood
Blood (2018) 132 (Supplement 1): 5280.
https://doi.org/10.1182/blood-2018-99-116093
Published: 2018
Journal Articles

Clinical Significance of Ck2 (CSNK2) and C-Myc Expression in Childhood Acute Lymphoblastic Leukemia

Paola Bonaccorso, Manuela La Rosa, Nellina Andriano, Valeria Iachelli, Emanuela Cannata, MD, Francesco Bellia, MD, Marinella Licciardello, MD PhD, Andrea Di Cataldo, MD PhD, Giovanna Russo, MD PhD, Luca Lo Nigro, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 5269.
https://doi.org/10.1182/blood.V128.22.5269.5269
Published: 2016
Journal Articles

Characterization of CD9-CXCL12-CXCR4 Expression in Biological Subtypes of Childhood ACUTE Lymphoblastic Leukemia: Preliminary Findings and Future Perspectives

Valeria Iachelli, Nellina Andriano, Paola Bonaccorso, Manuela La Rosa, Emanuela Cannata, MD, Piera Samperi, MD, Milena La Spina, MD, Andrea Di Cataldo, MD PhD, Giovanna Russo, MD PhD, Luca Lo Nigro, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 5278.
https://doi.org/10.1182/blood.V128.22.5278.5278
Published: 2016
Journal Articles

Dissecting the DNA Repair Machinery in Biological Subgroups of Childhood Acute Lymphoblastic Leukemia

Nellina Andriano, Valeria Iachelli, Paola Bonaccorso, Manuela La Rosa, Emanuela Cannata, MD, Vito Miraglia, MD, Salvatore D'Amico, MD, Andrea Di Cataldo, MD PhD, Giovanna Russo, MD PhD, Luca Lo Nigro, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 5279.
https://doi.org/10.1182/blood.V128.22.5279.5279
Published: 2016
Journal Articles

Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000

Clinical Trials & Observations
Anja Möricke, Martin Zimmermann, Maria Grazia Valsecchi, Martin Stanulla, Andrea Biondi, Georg Mann, Franco Locatelli, Giovanni Cazzaniga, Felix Niggli, Maurizio Aricò, Claus R. Bartram, Andishe Attarbaschi, Daniela Silvestri, Rita Beier, Giuseppe Basso, Richard Ratei, Andreas E. Kulozik, Luca Lo Nigro, Bernhard Kremens, Jeanette Greiner, Rosanna Parasole, Jochen Harbott, Roberta Caruso, Arend von Stackelberg, Elena Barisone, Claudia Rössig, Valentino Conter, Martin Schrappe
Journal: Blood
Blood (2016) 127 (17): 2101–2112.
https://doi.org/10.1182/blood-2015-09-670729
Published: 2016
Includes: Supplemental data
Journal Articles

Novel Strategies to Treat Children with Refractory or Relapsed Acute Myeloid Leukemia

Luca Lo Nigro, MD,PhD, Emanuela Cannata, MD, Piera Samperi, MD, Silvana Munda, BBD, Daria Bottino, MDPhD, Elena Mirabile, PhD, Andrea Di Cataldo, MDPhD, Giovanna Russo, MDPhD
Journal: Blood
Blood (2015) 126 (23): 4927.
https://doi.org/10.1182/blood.V126.23.4927.4927
Published: 2015
Journal Articles

Loss of PTEN in Pediatric T-Cell Acute Lymphoblastic Leukemia Patients: Proteomic and Molecular Characterization

Paola Bonaccorso, Cristina Bugarin, Chiara Buracchi, Grazia Fazio, Maddalena Paganin, Giuseppe Basso, Andrea Biondi, Giovanni Cazzaniga, Luca Lo Nigro, Giuseppe Gaipa
Journal: Blood
Blood (2014) 124 (21): 2408.
https://doi.org/10.1182/blood.V124.21.2408.2408
Published: 2014
Journal Articles

Role of Allogeneic Hematopoietic Stem Cell Transplantation in t(4;11) Positive Acute Lymphoblastic Leukemia (ALL): A Retrospective Multicenter Study of the Italian Association of Pediatric Hematology and Oncology (AIEOP)

Luca Lo Nigro, Marco Zecca, MD, Franca Fagioli, MD, Edoardo Lanino, Chiara Messina, Marco Rabusin, MD, Domenico Ripaldi, MD, Attilio Rovelli, MD, Arcangelo Prete, Franco Locatelli
Journal: Blood
Blood (2014) 124 (21): 1243.
https://doi.org/10.1182/blood.V124.21.1243.1243
Published: 2014
Journal Articles

CRLF2 over-Expression Is a Poor Prognostic Marker in Children with High Risk T-Cell Acute Lymphoblastic Leukemia

Chiara Palmi, Daniela Silvestri, Ilaria Bronzini, Gunnar Cario, Angela Savino, Maddalena Paganin, Barbara Buldini, Marta Galbiati, Martina U. Muckenthaler, Maurizio Arico, Elena Barisone, Fiorina Casale, Franco Locatelli, Luca Lo Nigro, Concetta Micalizzi, Rosanna Parasole, Andrea Pession, Maria Caterina Putti, Nicola Santoro, Anna Maria Testi, Ottavio Ziino, Andreas E Kulozik, Martin Zimmermann, PhD, Martin Schrappe, Giuseppe Basso, Andrea Biondi, Maria Grazia Valsecchi, Martin Stanulla, Valentino Conter, Geertruy te Kronnie, Giovanni Cazzaniga
Journal: Blood
Blood (2014) 124 (21): 1071.
https://doi.org/10.1182/blood.V124.21.1071.1071
Published: 2014
Journal Articles

FLT3-ITD As a Target for Minimal Residual Disease Monitoring in Early T-Cell Precursor (ETP) Acute Lymphoblastic Leukemia

Nellina Andriano, Barbara Buldini, Daniela Silvestri, Tiziana Villa, Franco Locatelli, Rosanna Parasole, Elena Barisone, Anna Maria Testi, Andrea Biondi, Maria Grazia Valsecchi, Valentino Conter, Giuseppe Basso, Luca Lo Nigro, Giovanni Cazzaniga
Journal: Blood
Blood (2014) 124 (21): 1073.
https://doi.org/10.1182/blood.V124.21.1073.1073
Published: 2014
Journal Articles

Outcome of Early T-Cell Precursor Acute Lymphoblastic Leukemia in AIEOP Patients Treated with the AIEOP-BFM ALL 2000 Study

Valentino Conter, Maria Grazia Valsecchi, Barbara Buldini, Rosanna Parasole, Franco Locatelli, Antonella Colombini, Maurizio Arico', Carmelo Rizzari, Maria Caterina Putti, Elena Barisone, Luca Lo Nigro, Nicola Santoro, Ottavio Ziino, Andrea Pession, Anna Maria Testi, Concetta Micalizzi, Fiorina Casale, Daniela Silvestri, Giovanni Cazzaniga, Andrea Biondi, Giuseppe Basso
Journal: Blood
Blood (2014) 124 (21): 3780.
https://doi.org/10.1182/blood.V124.21.3780.3780
Published: 2014