1-11 of 11
genes, apc
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Animal Models Demonstrate a Critical Role of Factor VIII in Par4- and Platelet-Mediated Pathology

Free
Michelle Castillo, BS, Quihui Yang, MD PhD, Dosia McKinney, Qizhen Shi, MD PhD, Rashmi Sood, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1057.
https://doi.org/10.1182/blood-2019-123290
Published: 2019
Journal Articles

Extravascular coagulation in hematopoietic stem and progenitor cell regulation

Free
T. Son Nguyen, Tsvee Lapidot, Wolfram Ruf
Journal: Blood
Blood (2018) 132 (2): 123–131.
https://doi.org/10.1182/blood-2017-12-768986
Published: 2018
Journal Articles

Cytoprotective activated protein C averts Nlrp3 inflammasome–induced ischemia-reperfusion injury via mTORC1 inhibition

Free
Sumra Nazir, Ihsan Gadi, Moh’d Mohanad Al-Dabet, Ahmed Elwakiel, Shrey Kohli, Sanchita Ghosh, Jayakumar Manoharan, Satish Ranjan, Fabian Bock, Ruediger C. Braun-Dullaeus, Charles T. Esmon, Tobias B. Huber, Eric Camerer, Chris Dockendorff, John H. Griffin, Berend Isermann, Khurrum Shahzad
Journal: Blood
Blood (2017) 130 (24): 2664–2677.
https://doi.org/10.1182/blood-2017-05-782102
Published: 2017
Includes: Supplemental data
Journal Articles

On PAR with aPC to target inflammasomes

Free
Steven R. Lentz
Journal: Blood
Blood (2017) 130 (24): 2579–2581.
https://doi.org/10.1182/blood-2017-09-806307
Published: 2017
Journal Articles

Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function

Free
Thati Madhusudhan, Hongjie Wang, Sanchita Ghosh, Wei Dong, Varun Kumar, Moh'd Mohanad Al-Dabet, Jayakumar Manoharan, Sumra Nazir, Ahmed Elwakiel, Fabian Bock, Shrey Kohli, Andi Marquardt, Ibrahim Sögüt, Khurrum Shahzad, Andreas J. Müller, Charles T. Esmon, Peter P. Nawroth, Jochen Reiser, Triantafyllos Chavakis, Wolfram Ruf, Berend Isermann
Journal: Blood
Blood (2017) 130 (12): 1445–1455.
https://doi.org/10.1182/blood-2017-02-767921
Published: 2017
Includes: Supplemental data
Journal Articles

Diabetic kidney disease: as easy as aPC?

Free
James D. McFadyen, Mark E. Cooper
Journal: Blood
Blood (2017) 130 (12): 1390–1391.
https://doi.org/10.1182/blood-2017-08-798314
Published: 2017
Journal Articles

Coagulation factor V mediates inhibition of tissue factor signaling by activated protein C in mice

Free
Hai Po H. Liang, Edward J. Kerschen, Sreemanti Basu, Irene Hernandez, Mark Zogg, Shuang Jia, Martin J. Hessner, Raffaella Toso, Alireza R. Rezaie, José A. Fernández, Rodney M. Camire, Wolfram Ruf, John H. Griffin, Hartmut Weiler
Journal: Blood
Blood (2015) 126 (21): 2415–2423.
https://doi.org/10.1182/blood-2015-05-644401
Published: 2015
Includes: Supplemental data
Journal Articles

Antibodies associated with heparin-induced thrombocytopenia (HIT) inhibit activated protein C generation: new insights into the prothrombotic nature of HIT

Free
M. Anna Kowalska, Sriram Krishnaswamy, Lubica Rauova, Li Zhai, Vincent Hayes, Karine Amirikian, Jeffrey D. Esko, Daniel W. Bougie, Richard H. Aster, Douglas B. Cines, Mortimer Poncz
Journal: Blood
Blood (2011) 118 (10): 2882–2888.
https://doi.org/10.1182/blood-2011-02-335208
Published: 2011
Includes: Supplemental data
Journal Articles

Niessen F, Furlan-Freguia C, Fernández JA, Mosnier LO, Castellino FJ, Weiler H, Rosen H, Griffin JH, Ruf W. Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality. Blood . 2009;113(12): 2859–2866 .

Free
Journal: Blood
Blood (2011) 117 (26): 7188.
https://doi.org/10.1182/blood-2011-05-354621
Published: 2011
Journal Articles

The protein C pathway in tissue inflammation and injury: pathogenic role and therapeutic implications

Free
Silvio Danese, Stefania Vetrano, Li Zhang, Victoria A. Poplis, Francis J. Castellino
Journal: Blood
Blood (2010) 115 (6): 1121–1130.
https://doi.org/10.1182/blood-2009-09-201616
Published: 2010
Journal Articles

Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality

Free
Frank Niessen, Christian Furlan-Freguia, José A. Fernández, Laurent O. Mosnier, Francis J. Castellino, Hartmut Weiler, Hugh Rosen, John H. Griffin, Wolfram Ruf
Journal: Blood
Blood (2009) 113 (12): 2859–2866.
https://doi.org/10.1182/blood-2008-12-192385
Published: 2009