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Issue Archive

Volume 9, Issue 6
March 25 2025
Blood Advances Cover Image for Volume 9, Issue 6

Table of Contents

INSIDE BLOOD ADVANCES

VWF-ADAMTS13 imbalance bridges infection to stroke
Jing-fei Dong,Cha Han
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Predicting risk in Hodgkin lymphoma for research and clinical practice
Ruohui Chen,Leo I. Gordon
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Targeting SDOH inequities in hematologic malignancies
Joanna M. Robles,Kimberly Montez
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Elderberry wine and promyelocytic leukemia
Clinical Trials & Observations
Steven D. Gore
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ADVANCES SNAPSHOT

Imetelstat: drugging telomerase in transfusion-dependent low- and intermediate-1–risk MDS
Clinical Trials & Observations
Joseph Cannova,Rafael Madero-Marroquin,Olatoyosi Odenike
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CLINICAL GUIDELINES

American Society of Hematology living guidelines on use of anticoagulation for thromboprophylaxis for patients with COVID-19: executive summary
Deborah M. Siegal,Eric K. Tseng,Holger J. Schünemann,Pantep Angchaisuksiri,Adam Cuker,Kathryn Dane,Maria T. DeSancho,David Diuguid,Daniel O. Griffin,Frederikus A. Klok,Alfred Ian Lee,Ignacio Neumann,Ashok Pai,Marc Righini,Kristen M. Sanfilippo,Deirdra R. Terrell,Elie A. Akl,Reyad Al Jabiri,Yazan Al Jabiri,Angela M. Barbara,Antonio Bognanni,Imad Bou Akl,Mary Boulos,Romina Brignardello-Petersen,Matthew Chan,Rana Charide,Luis E. Colunga-Lozano,Karin Dearness,Andrea J. Darzi,Heba Hussein,Samer G. Karam,Philipp Kolb,Razan Mansour,Gian Paolo Morgano,Rami Z. Morsi,Giovanna Muti-Schünemann,Menatalla K. Nadim,Atefeh Noori,Binu A. Philip,Thomas Piggott,Yuan Qiu,Yetiani Roldan Benitez,Finn Schünemann,Adrienne Stevens,Karla Solo,Wojtek Wiercioch,Reem A. Mustafa,Robby Nieuwlaat
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REVIEW ARTICLES

Peripheral T-cell lymphoma-NOS in children and adolescents: a review from the Children’s Oncology Group NHL Committee
Kaitlin J. Devine,Lindsay Schwartz,Nader Kim El-Mallawany
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Clinical use of measurable residual disease in adult ALL: recommendations from a panel of US experts
Nicholas J. Short,Ibrahim Aldoss,Daniel J. DeAngelo,Marina Konopleva,Jessica Leonard,Aaron C. Logan,Jae Park,Bijal Shah,Wendy Stock,Elias Jabbour
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CLINICAL TRIALS AND OBSERVATIONS

High pulmonary hypertension risk by echocardiogram shortens survival in polycythemia vera
Clinical Trials & Observations
Alexander J. Gazda,Di Pan,Katie Erdos,Ghaith Abu-Zeinah,Alexandra Racanelli,Evelyn M. Horn,Joseph M. Scandura
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Supplemental data
Validation of the revised 2022 European LeukemiaNet risk stratification in adult patients with acute myeloid leukemia
Clinical Trials & Observations
Leo Ruhnke,Marius Bill,Sven Zukunft,Jan-Niklas Eckardt,Silvia Schäfer,Sebastian Stasik,Maher Hanoun,Thomas Schroeder,Lars Fransecky,Björn Steffen,Stefan W. Krause,Sebastian Scholl,Andreas Hochhaus,Tim Sauer,Sabrina Kraus,Kerstin Schäfer-Eckart,Martin Kaufmann,Edgar Jost,Tim Brümmendorf,Christoph Schliemann,Jan-Henrik Mikesch,Utz Krug,Mathias Hänel,Anke Morgner,Markus Schaich,Andreas Neubauer,Roland Repp,Dirk Niemann,Ruth Seggewiss-Bernhardt,Achim Meinhardt,Johannes Kullmer,Ulrich Kaiser,Wolfgang Blau,Alexander Kiani,Götz Ulrich Grigoleit,Aristoteles Giagounidis,Alexander A. Wurm,Heidi Altmann,Jan Moritz Middeke,Johannes Schetelig,Carsten Müller-Tidow,Friedrich Stölzel,Claudia D. Baldus,Uwe Platzbecker,Hubert Serve,Martin Bornhäuser,Christian Thiede,Christoph Röllig
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HEALTH SERVICES AND OUTCOMES

Socioeconomic, racial-ethnic, household, and infrastructural disparities of hematologic cancer outcomes in the United States
David J. Fei-Zhang,Erik Wu,Alexander V. Stanisic,Lifang Hou,Leonidas C. Platanias,Stephen M. Ansell,Marquita W. Lewis-Thames,Sherif M. Badawy,Jonas Paludo
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LYMPHOID NEOPLASIA

Subclonal TP53 and KRAS variants combined with poor treatment response identify ultrahigh-risk pediatric patients with T-ALL
Tamara Kempter,Paulina Richter-Pechańska,Katarzyna Michel,Tobias Rausch,Büşra Erarslan-Uysal,Cornelia Eckert,Martin Zimmermann,Martin Stanulla,Martin Schrappe,Gunnar Cario,Stefan Köhrer,Andishe Attarbaschi,Jan O. Korbel,Joachim B. Kunz,Andreas E. Kulozik
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Pediatric relapsed/refractory ALK-positive anaplastic large cell lymphoma treatment and outcomes in the targeted-drug era
Lianna J. Marks,Victor Ritter,Jennifer E. Agrusa,Kala Y. Kamdar,Julie Rivers,Rebecca Gardner,Matthew J. Ehrhardt,Kaitlin J. Devine,Charles A. Phillips,Anne Reilly,Keith August,Joanna Weinstein,Prakash Satwani,Christopher J. Forlenza,Christine Moore Smith,Chelsee Greer,Zeinab Afify,Carol H. Lin,Jennifer A. Belsky,Hilda Ding,David Hoogstra,Keri Toner,Michael P. Link,Liora M. Schultz,Eric J. Lowe,Catherine Aftandilian
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Nivolumab and rituximab in treatment-naïve follicular lymphoma: the phase 2 1st FLOR study
Allison Barraclough,Sze Ting Lee,Melinda Burgess,Leonid Churilov,Geoff Chong,Denise Lee,Michael Gilbertson,Tineke Fancourt,Kate Manos,David S. Ritchie,Rachel M. Koldej,Andrew M. Scott,Colm Keane,Eliza A. Hawkes
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MYELOID NEOPLASIA

Relationship between additional mutations at diagnosis and treatment response in patients with essential thrombocythemia
Carole Mosnier,Sarah Bellal,Laurane Cottin,Françoise Boyer,Sandrine Lemoine,Amélie Bachelot,Joris Argentin,Bertille Pawlicki,Marie-Christine Copin,Rébecca Jouanneau-Courville,Anaïs Malinge,Jérémie Riou,Mathilde Hunault-Berger,Valérie Ugo,Corentin Orvain,Damien Luque Paz
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Supplemental data
Double mutant DNMT3A AML: a unique subtype experiencing increased DNA damage and poor prognosis
Emma L. Boertjes,Sanne Massaar,Annelieke Zeilemaker,Jolinda Konijnenburg,Melissa Rijken,François G. Kavelaars,Tim Grob,Jurjen Versluis,Bob Löwenberg,Peter J. M. Valk,Mathijs A. Sanders
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Anxiety and depression in patients with histiocytic neoplasms and their associated clinical features
Anne S. Reiner,Yesne Alici,Denise D. Correa,Dana Bossert,Allison M. Sigler,Deanna Fournier,Kathleen Brewer,Gaurav Goyal,Thomas M. Atkinson,Priya Marathe,Jun J. Mao,Katherine S. Panageas,Eli L. Diamond
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Supplemental data
ALLG APML5: bioavailability and safety of oral arsenic trioxide assessed during consolidation therapy for APL
Clinical Trials & Observations
Harry J. Iland,John Reynolds,Alan V. Boddy,Hayley B. Schultz,Liane Khoo,Shaun Fleming,Steven W. Lane,Nicholas Weber,Robin Gasiorowski,Tasman Armytage,Rosemary Harrup,Anne-Marie Watson,Peter Tan,Robin Filshie,Fiona Kwok,William Stevenson,Sam Yuen,Ashley P. Ng,Leesa Rowley,Paula Marlton,Andrew H. Wei,on behalf of the Australasian Leukaemia and Lymphoma Group
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PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

Characterization of the phenotypic consequences of the Duffy-null genotype
Clinical Trials & Observations
Micah R. Hysong,Megan M. Shuey,Jennifer E. Huffman,Paul Auer,Alexander Reiner,Laura M. Raffield
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PLASMA CELL DISORDERS

Health care systems as determinants of outcomes in multiple myeloma: final results from the Latin American MYLACRE study
Clinical Trials & Observations
Vania Hungria,Rafael Gaiolla,Kenny Galvez,Guillermina Remaggi,Natalia Schutz,Rosane Bittencourt,Angelo Maiolino,Guillermo Quintero-Vega,Maria Silvana Cugliari,Walter Moises Tobias Braga,Carolina Colaco Villarim,Edvan Crusoe,Alicia Ines Enrico,Gaston Caiero,Jandey Bigonha,Fernanda Lemos Moura,Jair Figueroa,Claudia Lucia Sossa Melo,Milton Lombana,Huiling Pei,Mariana Fernandez,Jaqueline Saes,Damila Cristina Trufelli
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RED CELLS, IRON, AND ERYTHROPOIESIS

Transcriptomic atlas reveals organ-specific disease tolerance in sickle cell mice
Anne Grunenwald,Julie Peliconi,Julien Lavergne,Margot Revel,Elodie Voilin,Tania Robe-Rybkine,Gilles Crambert,Jordan D. Dimitrov,Olivier Blanc-Brude,Lubka T. Roumenina
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THROMBOSIS AND HEMOSTASIS

Cost-effectiveness of Voncento prophylaxis vs on-demand treatment in von Willebrand disease in the United Kingdom
Michele Wilson,Giancarlo Castaman,Will Thomas,Carolyn Millar,Ginés Escolar,Wolfgang Miesbach,Cheryl McDade,Radovan Tomic,Songkai Yan
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Imbalanced VWF-ADAMTS13 axis contributes to the detrimental impact of a preceding respiratory tract infection on stroke
Rakesh B. Patel,Abhishek B. Jha,Aditi Jain,Abhishek K. Verma,Saurabh Saini,Joshua Muia,Prajwal Gurung,Stanley Perlman,Ivan Budnik,Anil K. Chauhan
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Supplemental data
VWF-ADAMTS13 imbalance bridges infection to stroke
Jing-fei Dong,Cha Han
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RESEARCH LETTERS

Combination therapies of porcupine inhibition with ruxolitinib, ibrutinib, or belumosudil in murine sclerodermatous GVHD
Xuezhi Hong,Yanhua Xiao,Liyan Xu,Lichong Shen,Ranjana Neelagar,Veda Devakumar,Thuong Trinh-Minh,Minrui Liang,Aleix Rius Rigau,Yun Zhang,Yi-Nan Li,Clara Dees,Andrea-Hermina Györfi,Daniel Wolff,Wolfgang Herr,Georg Schett,Jörg H. W. Distler,Alexandru-Emil Matei
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Differential effects of C5 inhibition, C3 inhibition, and alternative pathway inhibition on bacterial killing in vitro
Mendy ter Avest,Zenno de Boer,Saskia M. C. Langemeijer,Nicole C. A. J. van de Kar,Marien I. de Jonge,Rob ter Heine,Jeroen D. Langereis
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Supplemental data
G3BP1::CSF1R: a new and actionable gene fusion in acute megakaryoblastic leukemia
Xi Luo,Chi-Keung Cheng,Hoi-Yun Chan,Kam-Tong Leung,Chi-Kong Li,Nellie Yuk-Fei Chung,Herbert Augustus Pitts,Ke Tian,Yuet-Fong Kam,Margaret H.L. Ng
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Supplemental data
The A-HIPI prediction model in advanced-stage Hodgkin lymphoma: identification of risk groups and creation of an online tool
Clinical Trials & Observations
Matthew J. Maurer,Susan K. Parsons,Jenica N. Upshaw,Angie Mae Rodday,Raphael Mwangi,Sára Rossetti,Jonathan W. Friedberg,Andrea Gallamini,Massimo Federico,Eliza Hawkes,David Hodgson,Peter Johnson,Brian K. Link,Eric Mou,Kerry J. Savage,Pier Luigi Zinzani,Andrew M. Evens
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Predicting risk in Hodgkin lymphoma for research and clinical practice
Ruohui Chen,Leo I. Gordon
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Characteristics of infections after BCMA-directed CAR T-cell therapy for multiple myeloma: a real-world analysis
Tim Richardson,Daniel Schütte,Guido Kobbe,Ben-Niklas Baermann,Tobias A. W. Holderried,Friederike Schmitz,Martina Crysandt,Michael Hallek,Christoph Scheid,Udo Holtick,Oliver A. Cornely,Jannik Stemler,Sibylle C. Mellinghoff
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  • Cover Image

    Cover Image

    issue cover

    Schematic overview of the DNA (de)methylation cascade in humans, including de novo methylation by DNMT3A, spontaneous deamination of 5-methylcytosine, and base excision repair of G-T mismatches by methyl-CpG binding domain 4 and DNMT3A- thymine DNA glycosylase complexes. See the article by Boertjes et al.

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