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Phase 1 study of the selective BTK inhibitor zanubrutinib in B-cell malignancies and safety and efficacy evaluation in CLL
Tisagenlecleucel CAR T-cell therapy in secondary CNS lymphoma
Posttransplant cyclophosphamide vs antithymocyte globulin in HLA-mismatched unrelated donor transplantation
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Table of Contents
BLOOD COMMENTARIES
CLINICAL TRIALS AND OBSERVATIONS
Phase 1 study of the selective BTK inhibitor zanubrutinib in B-cell malignancies and safety and efficacy evaluation in CLL
Clinical Trials & Observations
Constantine S. Tam,Judith Trotman,Stephen Opat,Jan A. Burger,Gavin Cull,David Gottlieb,Rosemary Harrup,Patrick B. Johnston,Paula Marlton,Javier Munoz,John F. Seymour,David Simpson,Alessandra Tedeschi,Rebecca Elstrom,Yiling Yu,Zhiyu Tang,Lynn Han,Jane Huang,William Novotny,Lai Wang,Andrew W. Roberts
IMMUNOBIOLOGY AND IMMUNOTHERAPY
Tisagenlecleucel CAR T-cell therapy in secondary CNS lymphoma
Clinical Trials & Observations
Brief Report
Matthew J. Frigault,Jorg Dietrich,Maria Martinez-Lage,Mark Leick,Bryan D. Choi,Zachariah DeFilipp,Yi-Bin Chen,Jeremy Abramson,Jennifer Crombie,Philippe Armand,Lakshmi Nayak,Chris Panzini,Lauren S. Riley,Kathleen Gallagher,Marcela V. Maus
There is a Blood Commentary on this article in this issue.
MYELOID NEOPLASIA
Genomic landscape of neutrophilic leukemias of ambiguous diagnosis
Haijiao Zhang,Beth Wilmot,Daniel Bottomly,Kim-Hien T. Dao,Emily Stevens,Christopher A. Eide,Vishesh Khanna,Angela Rofelty,Samantha Savage,Anna Reister Schultz,Nicola Long,Libbey White,Amy Carlos,Rachel Henson,Chenwei Lin,Robert Searles,Robert H. Collins,Daniel J. DeAngelo,Michael W. Deininger,Tamara Dunn,Than Hein,Marlise R. Luskin,Bruno C. Medeiros,Stephen T. Oh,Daniel A. Pollyea,David P. Steensma,Richard M. Stone,Brian J. Druker,Shannon K. McWeeney,Julia E. Maxson,Jason R. Gotlib,Jeffrey W. Tyner
There is a Blood Commentary on this article in this issue.
THROMBOSIS AND HEMOSTASIS
Genetic determinants of VWF clearance and FVIII binding modify FVIII pharmacokinetics in pediatric hemophilia A patients
Laura L. Swystun,Kenichi Ogiwara,Orla Rawley,Christine Brown,Ilinca Georgescu,Wilma Hopman,Veerle Labarque,Christoph Male,Katharina Thom,Victor S. Blanchette,Manuel D. Carcao,David Lillicrap
TRANSPLANTATION
Posttransplant cyclophosphamide vs antithymocyte globulin in HLA-mismatched unrelated donor transplantation
Clinical Trials & Observations
Giorgia Battipaglia,Myriam Labopin,Nicolaus Kröger,Antonin Vitek,Boris Afanasyev,Inken Hilgendorf,Johannes Schetelig,Arnold Ganser,Didier Blaise,Maija Itälä-Remes,Jakob R. Passweg,Francesca Bonifazi,Jurgen Finke,Annalisa Ruggeri,Arnon Nagler,Mohamad Mohty
LETTER TO BLOOD
Natural history and cell of origin of TCF3-ZNF384 and PTPN11 mutations in monozygotic twins with concordant BCP-ALL
Clara Bueno,J. Ramón Tejedor,Rachael Bashford-Rogers,Laura González-Silva,Rafael Valdés-Mas,Antonio Agraz-Doblás,Rafael Díaz de la Guardia,Jordi Ribera,Lurdes Zamora,Chrystele Bilhou-Nabera,Nassera Abermil,Hélène Guermouche,Elodie Gouache,Guy Leverger,Mario F. Fraga,Agustín F. Fernández,Paola Ballerini,Ignacio Varela,Pablo Menendez
BLOOD WORK
ERRATUM
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Cover Image
Cover Image
B-cell receptor sequencing network for a monozygotic twin with concordant B-cell precursor acute lymphoblastic leukemia to track the clonal origin of the leukemia. See the article by Bueno et al on page 900.
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