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Brent H Koehn
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Journal Articles

Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD

Available to Purchase
Michael C. Zaiken, Sujeong Jin, Cameron S. McDonald-Hyman, Christina R. Hartigan, Peter T. Sage, Keli L. Hippen, Brent H. Koehn, Angela Panoskaltsis-Mortari, Megan J. Riddle, Cindy R. Eide, Jakub Tolar, Geoffrey R. Hill, Leo Luznik, Corey S. Cutler, Jerome R. Ritz, Leslie S. Kean, Ageliki Tsagaratou, Anjana Rao, Bruce R. Blazar
Journal: Blood
Blood (2025) 145 (24): 2813–2827.
https://doi.org/10.1182/blood.2024025036
Published: 2025
Includes: Supplemental data
Journal Articles

Targeting cell-surface VISTA expression on allospecific naïve T cells promotes tolerance

Available to Purchase
Brent H. Koehn, Elizabeth C. Nowak, Sladjana Skopelja-Gardner, Asim Saha, Michael C. Zaiken, Jeremy Allred, Yiyung Peng, Wilson L. Davis, III, Isabelle Le Mercier, Nicholas Schwertner, Michael J. Molloy, Jay Rothstein, Catherine Carriere, Megan J. Riddle, Cindy R. Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, Kyle D. Smith, Keli L. Hippen, Tae Kon Kim, Randolph J. Noelle, Bruce R. Blazar
Journal: Blood
Blood (2025) 145 (15): 1687–1700.
https://doi.org/10.1182/blood.2024025884
Published: 2025
Includes: Supplemental data
Journal Articles

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

Free
Brent H. Koehn, Asim Saha, Cameron McDonald-Hyman, Michael Loschi, Govindarajan Thangavelu, Lie Ma, Michael Zaiken, Josh Dysthe, Walker Krepps, Jamie Panthera, Keli Hippen, Stephen C. Jameson, Jeffrey S. Miller, Matthew A. Cooper, Christopher J. Farady, Takao Iwawaki, Jenny P.-Y. Ting, Jonathan S. Serody, William J. Murphy, Geoffrey R. Hill, Peter J. Murray, Vincenzo Bronte, David H. Munn, Robert Zeiser, Bruce R. Blazar
Journal: Blood
Blood (2019) 134 (19): 1670–1682.
https://doi.org/10.1182/blood.2019001950
Published: 2019
Journal Articles

Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD

Free
Benjamin M. Matta, Dawn K. Reichenbach, Xiaoli Zhang, Lisa Mathews, Brent H. Koehn, Gaelen K. Dwyer, Jeremy M. Lott, Franziska M. Uhl, Dietmar Pfeifer, Colby J. Feser, Michelle J. Smith, Quan Liu, Robert Zeiser, Bruce R. Blazar, Hēth R. Turnquist
Journal: Blood
Blood (2016) 128 (3): 427–439.
https://doi.org/10.1182/blood-2015-12-684142
Published: 2016
Includes: Supplemental data
Journal Articles

Protein Kinase C-Theta Interacts with mTORC2 and Vimentin to Limit Regulatory T-Cell Function

Free
Cameron McDonald-Hyman, BA, Govindarajan Thangavelu, PhD, James Muller, Guoan Zhang, PhD, Sudha Kumari, PhD, Asim Saha, PhD, Brent H. Koehn, PhD, Jason S. Mitchell, PhD, Brian T Fife, PhD, Jonathan S. Serody, MD, Mark J. Osborn, PhD, Keli L. Hippen, PhD, Ameeta Kelekar, PhD, David H. Munn, MD, Amnon Altman, PhD, Thomas A. Neubert, PhD, Michael L. Dustin, PhD, Bruce R. Blazar, MD
Journal: Blood
Blood (2015) 126 (23): 849.
https://doi.org/10.1182/blood.V126.23.849.849
Published: 2015
Journal Articles

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells

Free
Brent H. Koehn, Petya Apostolova, Jessica M. Haverkamp, Jeffrey S. Miller, Valarie McCullar, Jakub Tolar, David H. Munn, William J. Murphy, Willie June Brickey, Jonathan S. Serody, Dmitry I. Gabrilovich, Vincenzo Bronte, Peter J. Murray, Jenny P.-Y. Ting, Robert Zeiser, Bruce R. Blazar
Journal: Blood
Blood (2015) 126 (13): 1621–1628.
https://doi.org/10.1182/blood-2015-03-634691
Published: 2015
Includes: Supplemental data
Journal Articles

The IL-33/ST2 axis augments effector T-cell responses during acute GVHD

Free
Dawn K. Reichenbach, Vincent Schwarze, Benjamin M. Matta, Victor Tkachev, Elisabeth Lieberknecht, Quan Liu, Brent H. Koehn, Dietmar Pfeifer, Patricia A. Taylor, Gabriele Prinz, Heide Dierbach, Natalie Stickel, Yvonne Beck, Max Warncke, Tobias Junt, Annette Schmitt-Graeff, Susumu Nakae, Marie Follo, Tobias Wertheimer, Lukas Schwab, Jason Devlin, Simon C. Watkins, Justus Duyster, James L. M. Ferrara, Heth R. Turnquist, Robert Zeiser, Bruce R. Blazar
Journal: Blood
Blood (2015) 125 (20): 3183–3192.
https://doi.org/10.1182/blood-2014-10-606830
Published: 2015
Includes: Supplemental data
Journal Articles

Regulation of Immune Responses during Acute GvHD Via the IL-33/ST2 Axis

Free
Dawn K Reichenbach, PhD, Vincent Schwarze, Benjamin M Matta, PhD, Victor Tkachev, Elizabeth Lieberknecht, Quan Liu, MD PhD, Brent H Koehn, PhD, Dietmar Pfeifer, PhD, Patricia A Taylor, DVM, Gabriele Prinz, Heide Dierbach, Natalie Stickel, MS, Yvonne Beck, Max Warncke, Tobias Junt, Annette Schmitt-Graeff, MD, Susumu Nakae, Marie Follo, PhD, Tobias Wertheimer, Lukas Schwab, Jason Devlin, Simon C Watkins, PhD, Justus Duyster, James L.M. Ferrara, MD, D.Sc., Heth R. Turnquist, PhD, Robert Zeiser, Bruce R. Blazar, MD
Journal: Blood
Blood (2014) 124 (21): 844.
https://doi.org/10.1182/blood.V124.21.844.844
Published: 2014
Journal Articles

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality

Free
Asim Saha, Kazutoshi Aoyama, Patricia A. Taylor, Brent H. Koehn, Rachelle G. Veenstra, Angela Panoskaltsis-Mortari, David H. Munn, William J. Murphy, Miyuki Azuma, Hideo Yagita, Brian T. Fife, Mohammed H. Sayegh, Nader Najafian, Gerard Socie, Rafi Ahmed, Gordon J. Freeman, Arlene H. Sharpe, Bruce R. Blazar
Journal: Blood
Blood (2013) 122 (17): 3062–3073.
https://doi.org/10.1182/blood-2013-05-500801
Published: 2013
Includes: Supplemental data
Journal Articles

Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1–dependent mechanism that is up-regulated by interleukin-13

Free
Steven L. Highfill, Paulo C. Rodriguez, Qing Zhou, Christine A. Goetz, Brent H. Koehn, Rachelle Veenstra, Patricia A. Taylor, Angela Panoskaltsis-Mortari, Jonathan S. Serody, David H. Munn, Jakub Tolar, Augusto C. Ochoa, Bruce R. Blazar
Journal: Blood
Blood (2010) 116 (25): 5738–5747.
https://doi.org/10.1182/blood-2010-06-287839
Published: 2010
Includes: Supplemental data