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Gregory M Chen
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Journal Articles

STAT1-mediated interferon signatures associate with preclinical JAK-inhibitor sensitivity in T-cell acute lymphoblastic leukemia

Jason Xu, Jonathan H Sussman, Austin Yang, Satoshi Yoshimura, Jianzhong Hu, Changya Chen, Tiffaney L Vincent, Shovik Bandyopadhyay, Elizabeth Y Li, Tristan Lee Lim, Omar Elghawy, Adam Barsouk, Damjan Karanfilovski, Shira L Wald, Gregory M Chen, David Wei Wu, Haley Newman, Alexander Li, Yusha Sun, Chia-Hui Chen, Kathrin Maria Bernt, Brent L. Wood, Stuart Sheldon Winter, Kimberly P. Dunsmore, Elizabeth A. Raetz, Meenakshi Devidas, Stanley B Pounds, Mignon L. Loh, Stephen P Hunger, Mark Chiang, Caroline Diorio, Danika Di Giacomo, Petri Pölönen, Charles G. Mullighan, Jun J Yang, Kai Tan, David Trent Teachey
Journal: Blood
Blood blood.2025028566.
https://doi.org/10.1182/blood.2025028566
Published: 2025
Includes: Supplemental data
Journal Articles

In Vivo Persistence and Function of CAR19 T-Cell Products for Pediatric B-Cell Acute Lymphoblastic Leukemia Are Impacted By Media, Cytokine Supplementation and Metabolite Bioavailability during Ex Vivo Manufacturing

Caitlin R. Hopkins, Amanda M. DiNofia, Shannon L. Maude, Gregory M. Chen, Kwame Attah M. Boateng-Antwi, Jessica Perazzelli, Andres F. Mendez Corea, Alexander Shestov, Mercy Gohil, Yimei Li, Wei-Ting Hwang, Bakir Valentić, Shannon Christensen, Julie Jadlowsky, Regina M. Myers, Caroline Diorio, Megan M. Davis, Theresa Colligon, Gabriela Plesa, Don L. Siegel, Bruce Levine, Carl H. June, Roddy S. O'Connor, Stephan A. Grupp, Joseph A. Fraietta
Journal: Blood
Blood (2024) 144 (Supplement 1): 3473.
https://doi.org/10.1182/blood-2024-210324
Published: 2024
Journal Articles

Interferon-Activated Gene Signatures Associate with Chemotherapy Resistance and Sensitivity to JAK-Inhibition in Refractory ETP-ALL

Jason Xu, Jonathan Sussman, Austin Yang, Satoshi Yoshimura, Changya Chen, Omar Elghawy, Tiffaney Vincent, Caroline Diorio, Shovik Bandyopadyay, Jianzhong Hu, Alexander Lai Li, Gregory M. Chen, Chia-Hui Chen, Rawan Shraim, Haley Newman, Yang Ding, Elizabeth Li, Wenbao Yu, Anusha Thadi, Kyung Jin Ahn, Petri Pölönen, Abdelrahman Elsayed, David Frank, Elizabeth A. Raetz, Mignon L. Loh, Brent L. Wood, Stuart S. Winter, Kimberly P. Dunsmore, Meenakshi Devidas, Chunxu Qu, Stanley Pounds, Stephen P. Hunger, Charles G. Mullighan, Jun J. Yang, Kai Tan, David T. Teachey
Journal: Blood
Blood (2024) 144 (Supplement 1): 1464.
https://doi.org/10.1182/blood-2024-211090
Published: 2024
Journal Articles

Decade-Long Remissions of Leukemia Sustained By the Persistence of Activated CD4+ CAR T-Cells

J. Joseph Melenhorst, Gregory M Chen, Meng Wang, David L. Porter, Peng Gao, Shovik Bandyopadhyay, Iulian Pruteanu-Malinici, Christopher L Nobles, Sayantan Maji, Noelle V Frey, Saar Gill, Lifeng Tian, Irina Kulikovskaya, Megan M Davis, Joseph A Fraietta, Jennifer L Brogdon, Regina Young, David E Ambrose, Anne Chew, Bruce L Levine, Don L. Siegel, Cécile Alanio, E. John Wherry, Frederic D. Bushman, Simon F Lacey, Kai Tan, Carl H June
Journal: Blood
Blood (2021) 138 (Supplement 1): 166.
https://doi.org/10.1182/blood-2021-152664
Published: 2021