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Journal Articles

Protective Role of Oxaliplatin Among Platinum-Based Therapies in the Development of Therapy-Related Myeloid Neoplasms

Jeremy S Connors, Linda Zhang, Koji Sasaki, Courtney D. DiNardo, Nicholas J. Short, Naval Daver, Gautam Borthakur, Tapan M. Kadia, Hagop Kantarjian, Elias Jabbour, Margaret A Goodell, Guillermo Garcia-Manero, Koichi Takahashi

Blood (2023) 142 (Supplement 1): 4220.

https://doi.org/10.1182/blood-2023-190672

Published: 2023

Journal Articles

Clonal Hematopoiesis in Mice Is Common with Age and Accelerated By Microbial Exposure

Chiraag D. Kapadia, Matthew Yousefzadeh, Emily Mitchell, Duy Le, Nicholas Williams, Marcus A. Florez, Katherine Y. King, Laura Niedernhofer, Jyoti Nangalia, Margaret A. Goodell

Blood (2022) 140 (Supplement 1): 5741–5742.

https://doi.org/10.1182/blood-2022-168231

Published: 2022

Journal Articles

Combination of the Kdm-Family Inhibitor, Jib-04, Improves Response to Acute Myeloid Leukemia Cells to Venetoclax

Katharina Wohlan, Dandan Fan, Anna Guzman, Jianzhong Su, Margaret A. Goodell, Rachel E. Rau

Blood (2022) 140 (Supplement 1): 5953–5954.

https://doi.org/10.1182/blood-2022-160199

Published: 2022

Journal Articles

Nuclear Phase Separation Directs HOX Expression in Acute Myeloid Leukemia

Gandhar Datar, Archish Anand, Marwa Sadek, Christina Dollinger, English Laserna, Lorenzo Brunetti, Nidhi Sahni, Joshua Riback, Margaret A. Goodell

Blood (2022) 140 (Supplement 1): 724–725.

https://doi.org/10.1182/blood-2022-168430

Published: 2022

Journal Articles

Clonal Competition: Cisplatin Treatment Drives Dominance of TP53- over Tet2-Mutant Stem Cell Clones

Blood (2022) 140 (Supplement 1): 8590–8591.

https://doi.org/10.1182/blood-2022-164858

Published: 2022

Journal Articles

Genome-Wide CRISPR Screen Reveals Dependency of PPM1D- mutant Cells on DNA Repair

Linda Zhang, Joanne I. Hsu, Etienne D. Braekeleer, Hidetaka Uryu, Elsa Callen-Moreu, Andre Nussenzweig, Koichi Takahashi, George S Vassiliou, Margaret A. Goodell

Blood (2022) 140 (Supplement 1): 1994–1995.

https://doi.org/10.1182/blood-2022-166910

Published: 2022

Journal Articles

Cohesin Gene Haploinsufficiency Does Not Prevent Development of Inv(16) Acute Myeloid Leukemia

Shannon E. Conneely, Jason H. Rogers, Rogelio Aguilar, Kristen J Kurtz, Paul P. Liu, Margaret A. Goodell, Debananda Pati, Rachel E. Rau

Blood (2022) 140 (Supplement 1): 5868–5869.

https://doi.org/10.1182/blood-2022-165368

Published: 2022

Journal Articles

Clonal hematopoiesis: mechanisms driving dominance of stem cell clones

Grant A. Challen, Margaret A. Goodell

Blood (2020) 136 (14): 1590–1598.

https://doi.org/10.1182/blood.2020006510

Published: 2020

Journal Articles

Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis

Xiaotian Zhang, Xinyu Wang, Xue Qing David Wang, Jianzhong Su, Nagireddy Putluri, Ting Zhou, Ying Qu, Mira Jeong, Anna Guzman, Carina Rosas, Yun Huang, Arun Sreekumar, Wei Li, Margaret A. Goodell

Blood (2020) 135 (11): 845–856.

https://doi.org/10.1182/blood.2019003330

Published: 2020

Includes: Supplemental data

Journal Articles

Single-cell technology meets hematology: introduction to a review series

Margaret A. Goodell, David M. Bodine

Blood (2019) 133 (13): 1387–1388.

https://doi.org/10.1182/blood-2019-01-887224

Published: 2019

Journal Articles

Antibiotics Treatment Ameliorates TET2 Loss of Function Associated Hematological Malignancies

Hongxiang Zeng, PhD, Hailan He, MS, Jia Li, PhD, Wei Han, MS, Anna Guzman, Deqiang Sun, PhD, Katherine Y. King, MD PhD, Margaret A. Goodell, PhD, Yun Huang, PhD

Blood (2018) 132 (Supplement 1): 2610.

https://doi.org/10.1182/blood-2018-99-116424

Published: 2018

Journal Articles

Polycomb Group Proteins Recruit TET1 to Remove Aberrant DNA Methylation in Murine Embryonic Stem Cells

Yong Lei, PhD, Margaret A. Goodell, PhD

Blood (2018) 132 (Supplement 1): 2571.

https://doi.org/10.1182/blood-2018-99-116841

Published: 2018

Journal Articles

The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL

Etienne De Braekeleer, PhD MSc, Joanne Hsu, BS, Celine Hervieu, MSc, Konstantinos Tzelepis, PhD, Stefano Indraccolo, MD, Alan J. Warren, PhD FRCP, FRCPath, Irmela Jeremias, MD PhD, David Fernandez Antoran, PhD, Phil H Jones, PhD, Margaret A. Goodell, PhD, George S. Vassiliou

Blood (2018) 132 (Supplement 1): 2615.

https://doi.org/10.1182/blood-2018-99-118827

Published: 2018

Journal Articles

Large DNA Methylation Canyons Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity

Mira Jeong, PhD, Xiangfan Huang, Xiaotian Zhang, PhDBS, Jianzhong Su, Muhammad S Shamim, Ivan D Bochkov, Jaime M. Reyes, BS, Haiyoung Jung, Emily Beth Heikamp, MD PhD MSc, Aviva P Aiden, Wei Li, Erez Lieberman Aiden, Margaret A. Goodell, PhD

Blood (2018) 132 (Supplement 1): 534.

https://doi.org/10.1182/blood-2018-99-119485

Published: 2018

Journal Articles

Nearly a Third of Clonal Hematopoiesis-Associated DNMT3A Mutations Reduce Protein Stability and May be Associated with Poorer Prognosis

Yung-Hsin Huang, Ayala Tovy, PhD, Venkatasubramaniam Sundaramurthy, Jianzhong Su, Joanne Hsu, BS, Lian He, Anna Guzman, Yubin Zhou, Alexander Meissner, PhD, Wei Li, Margaret A. Goodell, PhD

Blood (2018) 132 (Supplement 1): 1315.

https://doi.org/10.1182/blood-2018-99-115275

Published: 2018

Journal Articles

Precise Modeling of IKZF1 Alterations in Human B-Cell Acute Lymphoblastic Leukemia Cell Lines Reveals Distinct Chemosensitivity, Homing, and Engraftment Properties

Jason H. Rogers, MS, Rohit Gupta, BS, Jaime M. Reyes, BS, Lorenzo Brunetti, MD PhD, Michael C. Gundry, BS, Tidie Song, Cade Johnson, Carlo D. D. Cristobal, BS, Margaret A. Goodell, PhD, Rachel E. Rau, MD

Blood (2018) 132 (Supplement 1): 549.

https://doi.org/10.1182/blood-2018-99-113056

Published: 2018

Journal Articles

DNA Epigenome Editing Using Crispr-Cas Suntag-Directed DNMT3A

Yung-Hsin Huang, BS, Su Jianzhong, PhD, Yong Lei, PhD, Michael C Gundry, BS, Xiaotian Zhang, BS, Mira Jeong, PhD, Wei Li, PhD, Margaret A Goodell, PhD

Blood (2016) 128 (22): 2707.

https://doi.org/10.1182/blood.V128.22.2707.2707

Published: 2016

Journal Articles

CRLF2 Overexpression Demonstrates Enhanced Leukemogenicity in Down Syndrome Hematopoietic Cells

Jacob J. Junco, PhD BS, Shan Liang, BS, Vishal Gokani, B.S., Vincent Ulysses Gant, PhD BS, Jaime Munoz, B.S., Allison Mayle, PhD, Chun Shik Park, PhD, H. Daniel Lacorazza, PhD, Margaret A Goodell, PhD, Karen R. Rabin, MD PhD

Blood (2016) 128 (22): 2708.

https://doi.org/10.1182/blood.V128.22.2708.2708

Published: 2016

Journal Articles

Crispr Engineering in CD34+ Progenitors Reveals Cis-Acting Regulatory Regions Mediating 3D Interactions and Stem Cell Fate Decisions

Mira Jeong, PhD, Yong Lei, PhD, Ivan Bochkov, Muhammad S Shamim, B.S., Anna G Guzman, Su-Chen Huang, M.S., Olga Dudchenko, PhD, Ido Machol, Michael C Gundry, BS, Huthayfa Mujahed, MS.c, Soren Lehmann, Erez S Lieberman, PhD, Margaret A Goodell, PhD

Blood (2016) 128 (22): 1466.

https://doi.org/10.1182/blood.V128.22.1466.1466

Published: 2016

Journal Articles

DOT1L as a therapeutic target for the treatment of DNMT3A -mutant acute myeloid leukemia

Rachel E. Rau, Benjamin A. Rodriguez, Min Luo, Mira Jeong, Allison Rosen, Jason H. Rogers, Carly T. Campbell, Scott R. Daigle, Lishing Deng, Yongcheng Song, Steve Sweet, Timothy Chevassut, Michael Andreeff, Steven M. Kornblau, Wei Li, Margaret A. Goodell

Blood (2016) 128 (7): 971–981.

https://doi.org/10.1182/blood-2015-11-684225

Published: 2016

Includes: Supplemental data

NARROW

Protective Role of Oxaliplatin Among Platinum-Based Therapies in the Development of Therapy-Related Myeloid Neoplasms

Clonal Hematopoiesis in Mice Is Common with Age and Accelerated By Microbial Exposure

Combination of the Kdm-Family Inhibitor, Jib-04, Improves Response to Acute Myeloid Leukemia Cells to Venetoclax

Nuclear Phase Separation Directs HOX Expression in Acute Myeloid Leukemia

Clonal Competition: Cisplatin Treatment Drives Dominance of TP53- over Tet2-Mutant Stem Cell Clones

Genome-Wide CRISPR Screen Reveals Dependency of PPM1D- mutant Cells on DNA Repair

Cohesin Gene Haploinsufficiency Does Not Prevent Development of Inv(16) Acute Myeloid Leukemia

Clonal hematopoiesis: mechanisms driving dominance of stem cell clones

Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis

Single-cell technology meets hematology: introduction to a review series

Antibiotics Treatment Ameliorates TET2 Loss of Function Associated Hematological Malignancies

Polycomb Group Proteins Recruit TET1 to Remove Aberrant DNA Methylation in Murine Embryonic Stem Cells

The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL

Large DNA Methylation Canyons Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity

Nearly a Third of Clonal Hematopoiesis-Associated DNMT3A Mutations Reduce Protein Stability and May be Associated with Poorer Prognosis

Precise Modeling of IKZF1 Alterations in Human B-Cell Acute Lymphoblastic Leukemia Cell Lines Reveals Distinct Chemosensitivity, Homing, and Engraftment Properties

DNA Epigenome Editing Using Crispr-Cas Suntag-Directed DNMT3A

CRLF2 Overexpression Demonstrates Enhanced Leukemogenicity in Down Syndrome Hematopoietic Cells

Crispr Engineering in CD34+ Progenitors Reveals Cis-Acting Regulatory Regions Mediating 3D Interactions and Stem Cell Fate Decisions

DOT1L as a therapeutic target for the treatment of DNMT3A -mutant acute myeloid leukemia

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American Society of Hematology

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American Society of Hematology

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