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Mithat Gönen
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Journal Articles

The simple c-reactive protein (CRP) to albumin ratio (CAR) stratifies treatment response and survival following chimeric antigen receptor T-cell therapy for non-Hodgkin's lymphoma

Free
Richard Lin, Maria Bromberg, Amethyst Saldia, Allison Parascondola, Molly Hogan, Emma Pavkovic, Roni Shouval, Mika Geva, Marina Gomez-Llobell, Silvia Escribano-Serrat, Sigrun Einarsdottir, Sandeep Raj, Lia Palomba, Parastoo Dahi, Michael Scordo, Gunjan Shah, Alexander Boardman, Lorenzo Falchi, Jennifer Lue, Gilles Salles, Craig Sauter, Jae Park, Miguel-Angel Perales, Paul Hamlin, Mithat Gonen, Sergio Giralt
Journal: Blood
Blood (2025) 146 (Supplement 1): 7090.
https://doi.org/10.1182/blood-2025-7090
Published: 2025
Journal Articles

Pre-existing cognitive impairment is associated with reduced long-term survival following chimeric antigen receptor T-cell therapy for non-Hodgkin's lymphoma

Free
Richard Lin, Soo Jung Kim, Maria Bromberg, Roni Shouval, Molly Hogan, Allison Parascondola, Amethyst Saldia, Emma Pavkovic, Mika Geva, Marina Gomez-Llobell, Silvia Escribano-Serrat, Sigrun Einarsdottir, Lia Palomba, Parastoo Dahi, Michael Scordo, Gunjan Shah, Alexander Boardman, Lorenzo Falchi, Jennifer Lue, Gilles Salles, Craig Sauter, Jae Park, Miguel-Angel Perales, Paul Hamlin, Armin Shahrokni, Mithat Gonen, Sergio Giralt
Journal: Blood
Blood (2025) 146 (Supplement 1): 6296.
https://doi.org/10.1182/blood-2025-6296
Published: 2025
Journal Articles

Impact of holding therapy prior to apheresis on outcomes following CD19 CAR-T cell therapy in large B-cell lymphoma

Free
Marina Gomez-Llobell, Sarah Samorodnitsky, Silvia Escribano Serrat, Jaime Sanz, Sigrun Einarsdottir, Efrat Luttwak, Sandeep Raj, Mohammad Alhomoud, Eugene Brailovski, Kai Rejeski, Maria Isabel Sotelo, Burcin Agridag Ucpinar, Heiko Schoder, Parnian Shobeiri, Alexander Boardman, Jennifer Lue, Parastoo Dahi, Richard Lin, Michael Scordo, Lorenzo Falchi, Craig Sauter, Gunjan Shah, Lia Palomba, Gilles Salles, Jae Park, Mithat Gonen, Roni Shouval, Miguel-Angel Perales
Journal: Blood
Blood (2025) 146 (Supplement 1): 6328.
https://doi.org/10.1182/blood-2025-6328
Published: 2025
Journal Articles

Effectiveness of second-line therapies following upfront daratumumab plus bortezomib, cyclophosphamide and dexamethasone: A new benchmark

Free
Eugene Brailovski, Xia Wu, Grace Gallagher, Mithat Gonen, Andrew Staron, Abhishek Janardan, Vaishali Sanchorawala, Christopher Wanjiku, Sascha Tuchman, Amelia Piteo, Jeffrey Zonder, Alfred Chung, Victor Jimenez-Zepeda, Raymond Comenzo, Heather Landau
Journal: Blood
Blood (2025) 146 (Supplement 1): 5746.
https://doi.org/10.1182/blood-2025-5746
Published: 2025
Journal Articles

Long-term cardiovascular outcomes in patients with lymphoma who had early post-CAR-T cardiovascular events: A multi-center, international study

Free
Elan Baskir, Tobias Tix, Mohammad Alhomoud, Samantha Brown, Mithat Gonen, Sigrun Einarsdottir, Ali Abed Al Wahad, Alexander Boardman, Veit Buecklein, James Di Palma-Grisi, Zachary Epstein-Peterson, Silvia Escribano Serrat, Lorenzo Falchi, Marina Gomez-Llobell, Andre Goy, Uri Greenbaum, Manhal Habib, Jabour Halloun, Andrew Ip, Sapir Israeli, Richard Lin, Danny Luan, Jennifer Lue, Efrat Luttwak, Lia Palomba, Jae Park, Sandeep Raj, Kai Rejeski, Alfredo Rivas-Delgado, Gilles Salles, Craig Sauter, Michael Scordo, Gunjan Shah, Marion Subklewe, Sergio Giralt, Miguel-Angel Perales, Roni Shouval, Ann Jakubowski, Jennifer Liu, Ofrat Katz, Parastoo Dahi
Journal: Blood
Blood (2025) 146 (Supplement 1): 3723.
https://doi.org/10.1182/blood-2025-3723
Published: 2025
Journal Articles

Population Pharmacokinetic Model Identifies an Optimal Fludarabine Exposure for Improved Outcomes after CD19-Directed CAR T Cell Therapy for Aggressive B-NHL: Analysis from the Cell Therapy Consortium

Free
Michael Scordo, Jessica R. Flynn, Sean M. Devlin, Mithat Gonen, Allison Parascondola, Ana Alarcon Tomas, Roni Shouval, Jamie Brower, David L. Porter, Stephen J. Schuster, Veronika Bachanova, Joseph E. Maakaron, Richard T. Maziarz, Loretta J. Nastoupil, Joseph P. McGuirk, Olalekan O. Oluwole, Andrew Ip, Lori A. Leslie, Michael R. Bishop, Peter A. Riedell, Miguel-Angel Perales
Journal: Blood
Blood (2022) 140 (Supplement 1): 1588–1591.
https://doi.org/10.1182/blood-2022-164674
Published: 2022
Journal Articles

Interventions and outcomes of adult patients with B-ALL progressing after CD19 chimeric antigen receptor T-cell therapy

Free
Clinical Trials & Observations
Kitsada Wudhikarn, Jessica R. Flynn, Isabelle Rivière, Mithat Gönen, Xiuyan Wang, Brigitte Senechal, Kevin J. Curran, Mikhail Roshal, Peter G. Maslak, Mark B. Geyer, Elizabeth F. Halton, Claudia Diamonte, Marco L. Davila, Michel Sadelain, Renier J. Brentjens, Jae H. Park
Journal: Blood
Blood (2021) 138 (7): 531–543.
https://doi.org/10.1182/blood.2020009515
Published: 2021
Includes: Supplemental data
Journal Articles

Clinical Factors Associated with Improved Survival Following Allogeneic HSCT after CD19 CAR Therapy in Adult Patients with Relapsed B-ALL

Free
Jae H. Park, MD, Jessica Flynn, BS, Mithat Gonen, Yvette Bernal, MS, Claudia Diamonte, RN, Elizabeth Halton, NP-BC AOCNP, Xiuyan Wang, PhD, Isabelle Riviere, PhD, Michel Sadelain, MD PhD, Renier J. Brentjens, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1348.
https://doi.org/10.1182/blood-2019-129343
Published: 2019
Journal Articles

RNA Binding Protein Syncrip Regulates the Leukemia Stem Cell Program

Free
Ly P. Vu, PhD, Camila Prieto, Elianna Amin, PhD, Gerard Minuesa, PhD, Sagar Chhangawala, Maria J Vidal, PhD, Andrei V. Krivtsov, PhD, Tim Chou, Trevor Barlowe, BA, James Taggart, BS, Patrick Tivnan, BS, Raquel P. Deering, Mithat Gonen, PhD, Maria E Figueroa, MD, Elisabeth Paietta, PhD, Martin S. Tallman, MD, Ari Melnick, MD, Ross L. Levine, MD, Fatima Al-Shahrour, PhD, Marcus Järås, Lisa Chu, Ralph Garippa, PhD, Christopher Lengner, PhD, Scott A. Armstrong, MD PhD, Glenn Cowley, PhD, David Root, PhD, John G Doench, PhD, Leandro Cerchietti, MD, Christina Leslie, PhD, Benjamin Ebert, Michael G. Kharas, PhD
Journal: Blood
Blood (2016) 128 (22): 739.
https://doi.org/10.1182/blood.V128.22.739.739
Published: 2016
Journal Articles

Genomic and Proteomic Analysis of Primary Chemoresistance and Induction Failure in Acute Myeloid Leukemia

Free
Fiona Brown, PhD, Eric Still, Paolo Cifani, PhD, Scott Ficarro, PhD, Gayle Pouliot, MD PhD, Esther Drill, PhD, Mithat Gonen, PhD, Jie He, PhD, Sohail Balasubramanian, M.S., Shan Zhong, PhD, Dean Pavlick, Bahar Yilmazel, Andrei V. Krivtsov, PhD, Todd A. Alonzo, PhD, Soheil Meshinchi, MD PhD, Steven M. Kornblau, MD, Richard M. Stone, MD, Guido Marcucci, MD, John C. Byrd, MD, Ross L. Levine, MD, Scott A. Armstrong, MD PhD, Nathanael Gray, PhD, Jarrod Marto, PhD, Alex Kentsis, MD PhD
Journal: Blood
Blood (2015) 126 (23): 88.
https://doi.org/10.1182/blood.V126.23.88.88
Published: 2015
Journal Articles

Integrative Analysis of the Mutational Landscape of Mouse and Human AML Identifies Functionally Relevant Leukemia Disease Alleles

Free
Megan A. Hatlen, PhD, Kanika Arora, MS, Vladimir Vacic, PhD, Ewa A. Grabowska, BS, Willey Liao, BS, Bridget Riley-Gillis, PhD, Dayna M. Oschwald, BS, Lan Wang, PhD, Jacob E. Joergens, Alan H. Shih, MD PhD, Franck Rapaport, PhD, Shengqing Gu, PhD, Francesca Voza, BS, Takashi Asai, MD PhD, Benjamin Neel, MD PhD, Michael G. Kharas, PhD, Mithat Gonen, PhD, Ross L. Levine, MD, Stephen D. Nimer, MD
Journal: Blood
Blood (2015) 126 (23): 1247.
https://doi.org/10.1182/blood.V126.23.1247.1247
Published: 2015
Journal Articles

Integrated DNA/RNA Profiling for Somatic Alterations in Adult B-Cell ALL

Free
Franck Rapaport, PhD, Jay Patel, Jie He, PhD, Timothy A Brennan, MS, Michelle Nahas, PhD, Sohail Balassubramanian, MS, Geoff Otto, PhD, Doron Lipson, PhD, Phil Stephens, PhD, Vincent A. Miller, MD, Janis Racevskis, MD, Mark R Litzow, MD, Peter H. Wiernik, MD, Anthony H. Goldstone, FRCP, FRCPath, Selina Luger, MD, Marcel van den Brink, MD PhD, Agnes Viale, PhD, Jacob M. Rowe, MD, Martin S. Tallman, MD, Ari Melnick, MD, Elisabeth Paietta, PhD, Mithat Gonen, PhD, Ross L. Levine, MD
Journal: Blood
Blood (2015) 126 (23): 1422.
https://doi.org/10.1182/blood.V126.23.1422.1422
Published: 2015
Journal Articles

Safety and Efficacy of Ferumoxytol for the Treatment of Iron Deficiency Anemia in a Community Based Hematology Clinic

Free
Erin DeBolt, B.S., PharmD candidate 2016, John A Wagoner, BS candidate 2016, Mark Tharnish, PharmD, Mithat Gonen, PhD, Dron Gauchan, MD, Ryan C. Ramaekers, MD, Douglas Clark, MD, Max Norvell, PharmD, Mehmet Copur, MD
Journal: Blood
Blood (2015) 126 (23): 4553.
https://doi.org/10.1182/blood.V126.23.4553.4553
Published: 2015
Journal Articles

Msi2 Maintains the MLL Leukemia Stem Cell Regulatory Program

Free
Sun Mi Park, PhD, Mithat Gönen, PhD, Ly P. Vu, PhD, Gerard Minuesa, PhD, Patrick Tivnan, Trevor Barlowe, James Taggart, Yuheng Lu, Raquel P Deering, PhD, Nir Hacohen, PhD, Maria Figueroa, MD, Elisabeth M. Paietta, PhD, Martin S. Tallman, MD, Ari M. Melnick, MD, Ross L. Levine, MD, Christina Leslie, PhD, Christopher J Lengner, PhD, Michael G Kharas, PhD
Journal: Blood
Blood (2014) 124 (21): 836.
https://doi.org/10.1182/blood.V124.21.836.836
Published: 2014
Journal Articles

Effect of Genetic Profiling on Prediction of Therapeutic Resistance and Survival in Adult Acute Myeloid Leukemia

Free
Roland B. Walter, MD PhD MS, Megan Othus, PhD, Elisabeth M. Paietta, PhD, Janis Racevskis, PhD, Hugo F Fernandez, MD, Ju-Whei Lee, PhD, Zhuoxin Sun, PhD, Martin S. Tallman, MD, Jay P. Patel, Mithat Gönen, PhD, Omar Abdel-Wahab, MD, Ross L Levine, MD, Elihu H. Estey, MD
Journal: Blood
Blood (2014) 124 (21): 941.
https://doi.org/10.1182/blood.V124.21.941.941
Published: 2014
Journal Articles

Genomic Analysis of Serial Samples from CLL Patients Identifies Clonal Events Associated with Disease Progression

Free
Jeffrey R Gardner, BS, MBA, Michelle Nahas, PhD, Jie He, PhD, Shlomzion Aumann, Mithat Gonen, Minal Patel, Kristina M. Knapp, BS, Maria Lia Palomba, MD, Roman Yelensky, PhD, Amy L Donahue, MS, Geoff Otto, PhD, Maria Arcila, MD, Nicole Lamanna, Mark G. Frattini, MD PhD, Ahmet Dogan, MD PhD, Jae H Park, MD, Doron Lipson, PhD, Martin S. Tallman, MD, Ross L. Levine, MD, Philip J. Stephens, PhD, Marcel R. M. van den Brink, MD PhD, Mark L Heaney, MD PhD, Vincent A. Miller, MD, Andrew D. Zelenetz, MD PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2014) 124 (21): 1954.
https://doi.org/10.1182/blood.V124.21.1954.1954
Published: 2014
Journal Articles

Minimal Residual Disease Assessment By Flow Cytometry in AML Is an Independant Prognostic Factor Even after Adjusting for Cytogenetic/Molecular Abnormalities

Free
Chezi Ganzel, MD, Zhuoxin Sun, PhD, Mithat Gonen, Jay P. Patel, Omar Abdel-Wahab, MD, Hugo F Fernandez, MD, Jacob M. Rowe, MD, Martin S. Tallman, MD, Ross L. Levine, MD, Elisabeth M. Paietta, PhD
Journal: Blood
Blood (2014) 124 (21): 1016.
https://doi.org/10.1182/blood.V124.21.1016.1016
Published: 2014
Journal Articles

Pilot Study To Evaluate The Prevalence Of Actionable Oncogenic Mutations In Patients With Relapsed Refractory Multiple Myeloma

Free
Alexander Lesokhin, MD, Mithat Gonen, Kaitlyn Redling, Nikoletta Lendvai, MD PhD, Hani Hassoun, MD, Heather Landau, MD, David J Chung, MD PhD, Guenther Koehne, MD, PhD, Minal Patel, Kristina W. Brennan, BS, Kai Wang, MD PhD, Eric M Sanford, BS, Tim Brennan, PhD, Geoff A. Otto, PhD, Michelle K. Nahas, PhD, Doron Lipson, PhD, Philip J. Stephens, PhD, Roman Yelensky, PhD, Vincent A. Miller, MD, Marcel Van Den Brink, MD, PhD, Ross L. Levine, MD, Ahmet Dogan, MD, PhD, Sergio A Giralt, MD
Journal: Blood
Blood (2013) 122 (21): 755.
https://doi.org/10.1182/blood.V122.21.755.755
Published: 2013
Journal Articles

CD25 expression status improves prognostic risk classification in AML independent of established biomarkers: ECOG phase 3 trial, E1900

Free
Clinical Trials & Observations
Mithat Gönen, Zhuoxin Sun, Maria E. Figueroa, Jay P. Patel, Omar Abdel-Wahab, Janis Racevskis, Rhett P. Ketterling, Hugo Fernandez, Jacob M. Rowe, Martin S. Tallman, Ari Melnick, Ross L. Levine, Elisabeth Paietta
Journal: Blood
Blood (2012) 120 (11): 2297–2306.
https://doi.org/10.1182/blood-2012-02-414425
Published: 2012
Includes: Supplemental data
Journal Articles

Genetic analysis of patients with leukemic transformation of myeloproliferative neoplasms shows recurrent SRSF2 mutations that are associated with adverse outcome

Free
Su-Jiang Zhang, Raajit Rampal, Taghi Manshouri, Jay Patel, Nana Mensah, Andrew Kayserian, Todd Hricik, Adriana Heguy, Cyrus Hedvat, Mithat Gönen, Hagop Kantarjian, Ross L. Levine, Omar Abdel-Wahab, Srdan Verstovsek
Journal: Blood
Blood (2012) 119 (19): 4480–4485.
https://doi.org/10.1182/blood-2011-11-390252
Published: 2012
Includes: Supplemental data